Cited by 385Infection Control and VentilationInhalation and Respiratory Drug DeliveryFluid Dynamics and Heat Transfer

Characterizations of particle size distribution of the droplets exhaled by sneeze

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Han, Z. Y., Weng, W. G., Huang, Q. Y.·2013·Journal of The Royal Society Interface

Abstract

This work focuses on the size distribution of sneeze droplets exhaled immediately at mouth. Twenty healthy subjects participated in the experiment and 44 sneezes were measured by using a laser particle size analyser. Two types of distributions are observed: unimodal and bimodal. For each sneeze, the droplets exhaled at different time in the sneeze duration have the same distribution characteristics with good time stability. The volume-based size distributions of sneeze droplets can be represented by a lognormal distribution function, and the relationship between the distribution parameters and the physiological characteristics of the subjects are studied by using linear regression analysis. The geometric mean of the droplet size of all the subjects is 360.1 µm for unimodal distribution and 74.4 µm for bimodal distribution with geometric standard deviations of 1.5 and 1.7, respectively. For the two peaks of the bimodal distribution, the geometric mean (the geometric standard deviation) is 386.2 µm (1.8) for peak 1 and 72.0 µm (1.5) for peak 2. The influences of the measurement method, the limitations of the instrument, the evaporation effects of the droplets, the differences of biological dynamic mechanism and characteristics between sneeze and other respiratory activities are also discussed.

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  1. WHO. 2004 The world health report, pp. 121-123. Geneva, Switzerland: World Health Organization.

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Authors
Han, Z. Y., Weng, W. G., & Huang, Q. Y.
Affiliations
Tsinghua University (CN)
Venue
Journal of The Royal Society Interface
Published
2013-11-06
Volume
10
Issue
88
Pages
20130560-20130560
ISSN
  • 1742-5662 (ISSN-L)
  • 1742-5689
OpenAlex
W2103114930
Cited by
383
References
56
Citations by year
2026: 15 · 2025: 20 · 2024: 27 · 2023: 54 · 2022: 67 · 2021: 97 · 2020: 92 · 2019: 7 · 2018: 1 · 2016: 1 · 2015: 1 · 2014: 1
FWCI
0.81
Type
journal article
Language
en
Open access
Locations
  • Journal of The Royal Society Interface (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Natural Science Foundation of China (51076073, 91024018)
  • Tsinghua University
Topics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Infection Control and Ventilation
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Inhalation and Respiratory Drug Delivery
  • Physical Sciences › Engineering › Computational Mechanics › Fluid Dynamics and Heat Transfer
Keywords
sneezing, droplet size distribution, respiratory droplets, lognormal distribution, bimodal distribution, exhaled particles, droplet evaporation, respiratory physiology, airborne transmission
MeSH terms
Adolescent, Adult, Aerosols, Female, Humans, Male, Models, Biological, Particle Size, Sneezing

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