The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Bacterial strategies of resistance to antimicrobial peptides
Open accessAbstract
Antimicrobial peptides (AMPs) are a key component of the host's innate immune system, targeting invasive and colonizing bacteria. For successful survival and colonization of the host, bacteria have a series of mechanisms to interfere with AMP activity, and AMP resistance is intimately connected with the virulence potential of bacterial pathogens. In particular, because AMPs are considered as potential novel antimicrobial drugs, it is vital to understand bacterial AMP resistance mechanisms. This review gives a comparative overview of Gram-positive and Gram-negative bacterial strategies of resistance to various AMPs, such as repulsion or sequestration by bacterial surface structures, alteration of membrane charge or fluidity, degradation and removal by efflux pumps. This article is part of the themed issue ‘Evolutionary ecology of arthropod antimicrobial peptides’.
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Cites
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Cited by
Antimicrobial host defence peptides: functions and clinical potential
Mookherjee, N., Anderson, M. A., Haagsman, H. P., & Davidson, D. J. (2020) · Nature Reviews Drug Discovery · doi:10.1038/s41573-019-0058-8 · Cited by 1,502
Antimicrobial peptides: Application informed by evolution
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Role of Metabolic Endotoxemia in Systemic Inflammation and Potential Interventions
Mohammad, S., & Thiemermann, C. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2020.594150 · Cited by 585
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Antimicrobial Peptides and Their Therapeutic Potential for Bacterial Skin Infections and Wounds
Pfalzgraff, A., Brandenburg, K., & Weindl, G. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00281 · Cited by 481
Metadata
- Authors
- Joo, H.-S., Fu, C.-I., & Otto, M.
- Venue
- Philosophical Transactions of the Royal Society B: Biological Sciences
- Publisher
- The Royal Society
- Published
- 2016-05-26
- Volume
- 371
- Issue
- 1695
- Pages
- 20150292
- ISSN
- 0962-8436 (ISSN-L)
- 1471-2970
- OpenAlex
- W2345912746
- Cited by
- 360
- References
- 9
- FWCI
- 22.91
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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