Increased selectivity of clinical peripheral nerve interfaces
Abstract
Selective, spiral peripheral nerve interfaces have been implemented in several clinical applications. Modeling results and intraoperative validation studies of the Flat Interface Nerve Electrode (FINE) demonstrate that with single channel, monopolar stimulation the FINE can increase the selectivity of neural stimulation. We hypothesize the stimulation selectivity can be further improved and potentially equal to intrafascicular stimulation by more sophisticated stimulation fields and interfascicular placement of electrodes with directed stimulation surfaces. We have developed an accurate linear approximation to the double cable model that is fast enough to implement non-gradient descent optimization techniques. Simulations suggest that anodal surround field shaping and directed interfascicular stimulation can increase the stimulation selectivity without placing electrodes inside the fascicles.
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Modeling studies have predicted that this effect could be avoided by implanting directional contacts adjacent to the fascicles.
“Modeling studies have predicted that this effect could be avoided by implanting directional contacts adjacent to the fascicles [55].”
From Directed stimulation with interfascicular interfaces for peripheral nerve stimulation (2021) · cites this paper as [55]
Cites
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“activate [ 22 ]. This would significantly decrease the”
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A review for the peripheral nerve interface designer
Larson, C. E., & Meng, E. (2020) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2019.108523 · Cited by 133 · see citing works
Directed stimulation with interfascicular interfaces for peripheral nerve stimulation
Koppaka, S., Hess-Dunning, A., & Tyler, D. J. (2021) · Journal of Neural Engineering · doi:10.1088/1741-2552/ac33e8 · Cited by 7 · see citing works
Self-citation
- Authors
- Tyler, D. J., Peterson, E. J., Brill, N., & White, K.
- Affiliations
- Case Western Reserve University (US)
- Venue
- 2011 5th International IEEE/EMBS Conference on Neural Engineering
- Publisher
- IEEE
- Published
- 2011-04
- Pages
- 257-260
- ISSN
- 1948-3554 (ISSN-L)
- OpenAlex
- W2149161039
- Cited by
- 10
- References
- 23
- Citations by year
- 2024: 2 · 2023: 1 · 2022: 1 · 2021: 1 · 2019: 2 · 2018: 1 · 2014: 1 · 2013: 1
- FWCI
- 1.81
- Type
- conference paper
- Language
- en
- Open access
- closed
- Locations
- International IEEE/EMBS Conference on Neural Engineering (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Life Sciences › Neuroscience › Neurology › Vagus Nerve Stimulation Research
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
- Keywords
- peripheral nerve interfaces, stimulation selectivity, neurostimulation
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