Continuous glucose monitoring: A review of the evidence in type 1 and 2 diabetes mellitus
Abstract
Context and Aim: Continuous glucose monitoring (CGM) is becoming widely accepted as an adjunct to diabetes management. Compared to standard care, CGM can provide detailed information about glycaemic variability in an internationally standardised ambulatory glucose profile, enabling more informed user and clinician decision making. We aimed to review the evidence, user experience and cost‐effectiveness of CGM. Methods: A literature search was conducted by combining subject headings ‘CGM’ and ‘flash glucose monitoring’, with key words ‘type 1 diabetes’ and ‘type 2 diabetes’, limited to ‘1999 to current’. Further evidence was obtained from relevant references of retrieved articles. Results: There is a strong evidence for CGM use in people with type 1 diabetes, with benefits of reduced glycated haemoglobin and hypoglycaemia, and increased time in range. While the evidence for CGM use in type 2 diabetes is less robust, similar benefits have been demonstrated. CGM can improve diabetes‐related satisfaction in people with diabetes (PWD) and parents of children with diabetes, as well as the clinician experience. However, CGM does have limitations including cost, accuracy and perceived inconvenience. Cost‐effectiveness analyses have indicated that CGM is a cost‐effective adjunct to type 1 diabetes management that is associated with reduced diabetes‐related complications and hospitalisation. Conclusions: Continuous glucose monitoring is revolutionising diabetes management. It is a cost‐effective adjunct to diabetes management that has the potential to improve glycaemic outcomes and quality of life in PWD, especially type 1 diabetes.
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CGM systems have progressed from retrospective professional devices to sophisticated real-time monitors and automated closed-loop systems that integrate with insulin delivery.
“These systems have progressed from retrospective professional devices to sophisticated real-time monitors and automated closed-loop systems that integrate with insulin delivery [39].”
From Effectiveness of continuous glucose monitoring systems on glycemic control in adults with type 1 diabetes: A systematic review and meta-analysis (2025) · cites this paper as [39]
Mixed results have been reported on the use of CGM systems by people with type 2 diabetes mellitus.
“However, while the use of CGM systems has been shown to (further) improve therapy for people with T1DM [12, 13], mixed results have been reported on the use of CGM systems by people with T2DM [14, 15].”
From Self-Monitoring of Blood Glucose as an Integral Part in the Management of People with Type 2 Diabetes Mellitus (2022) · cites this paper as [15]
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- Authors
- Lin, R., Brown, F., James, S., Jones, J., & Ekinci, E.
- Affiliations
- Austin Hospital (AU)
- Melbourne Diabetes Education and Support Heidelberg Heights Vic. Australia
- University of the Sunshine Coast (AU)
- The University of Melbourne (AU)
- Corresponding author
- Ekinci, Elif
- Venue
- Diabetic Medicine
- Publisher
- Wiley
- Published
- 2021-03-06
- Volume
- 38
- Issue
- 5
- Pages
- e14528-e14528
- ISSN
- 0742-3071 (ISSN-L)
- 1464-5491
- OpenAlex
- W3121399117
- Cited by
- 197
- References
- 40
- Citations by year
- 2026: 36 · 2025: 52 · 2024: 40 · 2023: 42 · 2022: 20 · 2021: 7
- FWCI
- 4.18
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Diabetic Medicine (publishedVersion)
- PubMed (publishedVersion)
- Minerva Access (University of Melbourne) (submittedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Keywords
- continuous glucose monitoring, flash glucose monitoring, type 1 diabetes, type 2 diabetes, glycemic variability, HbA1c, hypoglycemia, time in range, cost-effectiveness, user experience, diabetes management, quality of life
- MeSH terms
- Glycemic Control, Blood Glucose, Cost-Benefit Analysis, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Glycated Hemoglobin, Hospitalization, Humans, Quality of Life, Blood Glucose Self-Monitoring, Patient Satisfaction, Diabetes Complications, History, 20th Century, History, 21st Century
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