B-Group vitamin production by lactic acid bacteria - current knowledge and potential applications: Vitamin production by LAB
Open accessAbstract
Although most vitamins are present in a variety of foods, human vitamin deficiencies still occur in many countries, mainly because of malnutrition not only as a result of insufficient food intake but also because of unbalanced diets. Even though most lactic acid bacteria (LAB) are auxotrophic for several vitamins, it is now known that certain strains have the capability to synthesize water-soluble vitamins such as those included in the B-group (folates, riboflavin and vitamin B(12) amongst others). This review article will show the current knowledge of vitamin biosynthesis by LAB and show how the proper selection of starter cultures and probiotic strains could be useful in preventing clinical and subclinical vitamin deficiencies. Here, several examples will be presented where vitamin-producing LAB led to the elaboration of novel fermented foods with increased and bioavailable vitamins. In addition, the use of genetic engineering strategies to increase vitamin production or to create novel vitamin-producing strains will also be discussed. This review will show that the use of vitamin-producing LAB could be a cost-effective alternative to current vitamin fortification programmes and be useful in the elaboration of novel vitamin-enriched products.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Escherichia coli and Salmonella :cellular and molecular biology
Neidhardt, F. C. (1996) · ASM Press eBooks · Cited by 8,230 · see citing works
Complete genome sequence of <i>Lactobacillus plantarum</i> WCFS1
Kleerebezem, M., Boekhorst, J., van Kranenburg, R., Molenaar, D., Kuipers, O. P., Leer, R., Tarchini, R., Peters, S. A., Sandbrink, H. M., Fiers, M. W. E. J., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0337704100 · Cited by 1,472 · see citing works
Harrison's Principles of Internal Medicine
Massarelli, J. J. (1984) · JAMA · doi:10.1001/jama.1984.03340300091039 · Cited by 1,132 · see citing works
Probiotics: an overview of beneficial effects
Ouwehand, A. C., Salminen, S., & Isolauri, E. (2002) · Antonie van Leeuwenhoek · doi:10.1023/a:1020620607611 · Cited by 1,045 · see citing works
Microbial production of vitamin B 12
J.-H. Martens, H. B. (2002) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-001-0902-7 · Cited by 732 · see citing works
Folate Production by Probiotic Bacteria
Rossi, M., Amaretti, A., & Raimondi, S. (2011) · Nutrients · doi:10.3390/nu3010118 · Cited by 653 · see citing works
COBALAMIN (COENZYME B 12 ): Synthesis and Biological Significance
Roth, J., Lawrence, J., & Bobik, T. (1996) · Annual Review of Microbiology · doi:10.1146/annurev.micro.50.1.137 · Cited by 566 · see citing works
Microbes from raw milk for fermented dairy products
Wouters, J. T. M., Ayad, E. H. E., Hugenholtz, J., & Smit, G. (2002) · International Dairy Journal · doi:10.1016/s0958-6946(01)00151-0 · Cited by 561 · see citing works
Encyclopaedia of food science, food technology, and nutrition
(1993) · Choice Reviews Online · doi:10.5860/choice.31-1853 · Cited by 515 · see citing works
Folic acid to reduce neonatal mortality from neural tube disorders
Blencowe, H. K., Cousens, S. N., Modell, B., & Lawn, J. E. (2010) · International Journal of Epidemiology · doi:10.1093/ije/dyq028 · Cited by 507 · see citing works
The biosynthesis of adenosylcobalamin (vitamin B12)
Warren, M. J., Raux, E., Schubert, H., & Escalante‐Semerena, J. C. (2002) · Natural Product Reports · doi:10.1039/b108967f · Cited by 484 · see citing works
Comparative Genomics of the Vitamin B12 Metabolism and Regulation in Prokaryotes
Rodionov, D. A., Vitreschak, A. G., Mironov, A. A., & Gelfand, M. S. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m305837200 · Cited by 472 · see citing works
Epidemiologic Studies of Folate and Colorectal Neoplasia: a Review
Giovannucci, E. L. (2002) · Journal of Nutrition · doi:10.1093/jn/132.8.2350s · Cited by 451 · see citing works
The potential of probiotics: a review.
Soccol, C. R., Vandenberghe, L. P. D. S., Spier, M. R., Medeiros, A. B. P., Yamaguishi, C. T., Lindner, J. D. D., Pandey, A., & Thomaz‐Soccol, V. (2010) · University of Zagreb University Computing Centre (SRCE) · Cited by 449 · see citing works
van de Guchte, M., Penaud, S., Grimaldi, C., Barbe, V., Bryson, K., Nicolas, P., Robert, C., Oztas, S., Mangenot, S., Couloux, A., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0603024103 · Cited by 417 · see citing works
Folate Production by Bifidobacteria as a Potential Probiotic Property
Pompei, A., Cordisco, L., Amaretti, A., Zanoni, S., Matteuzzi, D., & Rossi, M. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.01763-06 · Cited by 356 · see citing works
Biosynthesis of Vitamin B2 (Riboflavin)
Bacher, A., Eberhardt, S., Fischer, M. J., Kis, K., & Richter, G. (2000) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.20.1.153 · Cited by 316 · see citing works
Synthesis and utilisation of folate by yoghurt starter cultures and probiotic bacteria
Crittenden, R. G., Martinez, N. R., & PLAYNE, M. J. (2003) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(02)00170-8 · Cited by 270 · see citing works
Metabolic engineering of Agrobacterium sp. strain ATCC 31749 for production of an α-Gal epitope
Ruffing, A. M., & Chen, R. R. (2010) · Microbial Cell Factories · doi:10.1186/1475-2859-9-1 · Cited by 248 · see citing works
Effects of Cultivation Conditions on Folate Production by Lactic Acid Bacteria
Sybesma, W., Starrenburg, M. J. C., Tijsseling, L., Hoefnagel, M. H. N., & Hugenholtz, J. (2003) · Applied and Environmental Microbiology · doi:10.1128/aem.69.8.4542-4548.2003 · Cited by 247 · see citing works
Multireplicon genome architecture of Lactobacillus salivarius
Claesson, M. J., Li, Y., Leahy, S. C., Canchaya, C. A., van Pijkeren, J. P., Cerdeño-Tárraga, A. M., Parkhill, J., Flynn, S., O’Sullivan, G. C., Collins, J. K., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0511060103 · Cited by 226 · see citing works
Lactobacillus reuteri CRL1098 Produces Cobalamin
Taranto, M. P., Vera, J. L., Hugenholtz, J., de Valdez, G. F., & Sesma, F. J. M. (2003) · Journal of Bacteriology · doi:10.1128/jb.185.18.5643-5647.2003 · Cited by 221 · see citing works
Self-citationBurgess, C. M., Motherway, M. O., Sybesma, W., Hugenholtz, J., & van Sinderen, D. (2004) · Applied and Environmental Microbiology · doi:10.1128/aem.70.10.5769-5777.2004 · Cited by 219 · see citing works
Biosynthesis of cobalamin (vitamin B12): a bacterial conundrum
Raux, E., Schubert, H., & Warren, M. J. (2000) · Cellular and Molecular Life Sciences · doi:10.1007/pl00000670 · Cited by 211 · see citing works
Genetic engineering of Bacillus subtilis for the commercial production of riboflavin
Perkins, J. B., Sloma, A., HERMANN, T. E., Theriault, K., Zachgo, E. A., Erdenberger, T., Hannett, N. M., Chatterjee, N. P., Williams, V., II, Rufo, G. A., et al. (1999) · Journal of Industrial Microbiology & Biotechnology · doi:10.1038/sj.jim.2900587 · Cited by 201 · see citing works
Increased Production of Folate by Metabolic Engineering of Lactococcus lactis
Sybesma, W., Starrenburg, M. J. C., Kleerebezem, M., Mierau, I., de Vos, W. M., & Hugenholtz, J. (2003) · Applied and Environmental Microbiology · doi:10.1128/aem.69.6.3069-3076.2003 · Cited by 200 · see citing works
Changes in some components of soymilk during fermentation with bifidobacteria
Hou, J.-W., Yu, R., & Chou, C. (2000) · Food Research International · doi:10.1016/s0963-9969(00)00061-2 · Cited by 184 · see citing works
Nutraceutical production with food-grade microorganisms
Hugenholtz, J., & Smid, E. J. (2002) · Current Opinion in Biotechnology · doi:10.1016/s0958-1669(02)00367-1 · Cited by 168 · see citing works
Lamers, Y., Prinz‐Langenohl, R., Brämswig, S., et al. (2006) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/84.1.156 · Cited by 168 · see citing works
Folate levels in cultures of lactic acid bacteria
Lin, M., & Young, C.-M. (2000) · International Dairy Journal · doi:10.1016/s0958-6946(00)00056-x · Cited by 165 · see citing works
Bacterial vitamin B2, B11 and B12 overproduction: An overview
Burgess, C. M., Smid, E. J., & van Sinderen, D. (2009) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2009.04.012 · Cited by 164 · see citing works
Nutritional and Healthful Aspects of Cultured and Culture-Containing Dairy Foods
SHAHANI, K. M., & Chandan, R. C. (1979) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(79)83481-5 · Cited by 164 · see citing works
Plants need their vitamins too
Smith, A. G., Croft, M. T., Moulin, M., & Webb, M. E. (2007) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2007.04.009 · Cited by 162 · see citing works
How Nature Builds the Pigments of Life: the Conquest of Vitamin B 12
Battersby, A. R. (1994) · Science · doi:10.1126/science.8202709 · Cited by 161 · see citing works
Effects of yeasts and bacteria on the levels of folates in rye sourdoughs
Kariluoto, S., Aittamaa, M., Korhola, M., Salovaara, H. O., Vahteristo, L. T., & Piironen, V. I. (2005) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2005.06.013 · Cited by 159 · see citing works
Production of Menaquinones by Lactic Acid Bacteria
Morishita, T., Tamura, N., Makino, T., & Kudo, S. (1999) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(99)75424-x · Cited by 157 · see citing works
Biotechnological Production of Vitamin B2-Enriched Bread and Pasta
Capozzi, V., Menga, V., Digesù, A. M., Vita, P. D., van Sinderen, D., Cattivelli, L., Fares, C., & Spano, G. (2011) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf201519h · Cited by 146 · see citing works
A general method for selection of riboflavin-overproducing food grade micro-organisms
Burgess, C. M., Smid, E. J., Rutten, G., & van Sinderen, D. (2006) · Microbial Cell Factories · doi:10.1186/1475-2859-5-24 · Cited by 141 · see citing works
Multivitamin production in Lactococcus lactis using metabolic engineering
Sybesma, W. (2003) · Metabolic Engineering · doi:10.1016/j.ymben.2003.11.002 · Cited by 136 · see citing works
High-Level Folate Production in Fermented Foods by the B 12 Producer Lactobacillus reuteri JCM1112
dos Santos, F. B., Wegkamp, A., de Vos, W. M., Smid, E. J., & Hugenholtz, J. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.02719-07 · Cited by 134 · see citing works
Folic acid — vitamin and panacea or genetic time bomb?
Lucock, M. D., & Yates, Z. R. (2005) · Nature Reviews Genetics · doi:10.1038/nrg1558 · Cited by 132 · see citing works
Wegkamp, A., van Oorschot, W., de Vos, W. M., & Smid, E. J. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.02174-06 · Cited by 128 · see citing works
Conversion of Cobinamide into Adenosylcobamide in Bacteria and Archaea
Escalante‐Semerena, J. C. (2007) · Journal of Bacteriology · doi:10.1128/jb.00503-07 · Cited by 126 · see citing works
Martı́n, R., Olivares, M. M., Marín, M. L., Xaus, J., Fernández, L., & Rodríguez, J. M. (2005) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2005.03.007 · Cited by 113 · see citing works
The complete coenzyme B12 biosynthesis gene cluster of Lactobacillus reuteri CRL1098
dos Santos, F. B., Vera, J. L., van der Heijden, R. T. J. M., de Valdez, G. F., de Vos, W. M., Sesma, F. J. M., & Hugenholtz, J. (2008) · Microbiology · doi:10.1099/mic.0.2007/011569-0 · Cited by 113 · see citing works
Self-citationThe North/South Ireland Food Consumption Survey: mineral intakes in 18–64-year-old adults
Hannon, E. M., Kiely, M. E., Harrington, K., Robson, P. J., Strain, J., & Flynn, A. (2001) · Public Health Nutrition · doi:10.1079/phn2001189 · Cited by 105 · see citing works
Champagne, C. P., Tompkins, T. A., Buckley, N. D., & Green-Johnson, J. M. (2010) · Food Microbiology · doi:10.1016/j.fm.2010.06.003 · Cited by 104 · see citing works
Glatzle, D., Wf, K., Christeller, S., et al. (1970) · PubMed · Cited by 96 · see citing works
Production of Vitamin B12 in Genetically Engineered Propionibacterium freudenreichii
Piao, Y., Yamashita, M., Kawaraichi, N., Asegawa, R., Ono, H., & Murooka, Y. (2004) · Journal of Bioscience and Bioengineering · doi:10.1016/s1389-1723(04)00261-0 · Cited by 94 · see citing works
Effect of Fermentation on B-Vitamin Content of Milk in Sweden
Alm, L. (1982) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(82)82199-1 · Cited by 92 · see citing works
Pseudovitamin is the corrinoid produced by Lactobacillus reuteri CRL1098 under anaerobic conditions
dos Santos, F. B., Vera, J. L., Lamosa, P., de Valdez, G. F., de Vos, W. M., Santos, H., Sesma, F. J. M., & Hugenholtz, J. (2007) · FEBS Letters · doi:10.1016/j.febslet.2007.09.012 · Cited by 92 · see citing works
Self-citationThe North/South Ireland Food Consumption Survey: vitamin intakes in 18–64-year-old adults
O'Brien, M., Kiely, M. E., Harrington, K., Robson, P. J., Strain, J., & Flynn, A. (2001) · Public Health Nutrition · doi:10.1079/phn2001188 · Cited by 87 · see citing works
Wu, Q., Chen, T., Gan, Y., et al. (2007) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-007-1049-y · Cited by 84 · see citing works
Asrar, F. M., & O’Connor, D. L. (2005) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2005.02.006 · Cited by 82 · see citing works
Keuth, S., & Bisping, B. (1993) · Journal of Applied Bacteriology · doi:10.1111/j.1365-2672.1993.tb02798.x · Cited by 81 · see citing works
Blanck, H. M., Bowman, B. A., Serdula, M. K., Khan, L. K., Kohn, W. G., & Woodruff, B. A. (2002) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/76.2.430 · Cited by 73 · see citing works
LeBlanc, J. G., Rutten, G., Bruinenberg, P. M., Sesma, F. J. M., de Giori, G. S., & Smid, E. J. (2006) · Nutrition · doi:10.1016/j.nut.2006.01.002 · Cited by 72 · see citing works
Self-citationFabian, E., Majchrzak, D., Dieminger, B., Meyer, E., & Elmadfa, I. (2008) · Annals of Nutrition and Metabolism · doi:10.1159/000114408 · Cited by 70 · see citing works
Discovering Nature's Diverse Pathways to Vitamin B12: A 35-Year Odyssey
Scott, A. I. (2003) · The Journal of Organic Chemistry · doi:10.1021/jo020728t · Cited by 70 · see citing works
Production of riboflavin by metabolically engineered Corynebacterium ammoniagenes
Koizumi, S., Yonetani, Y., Maruyama, A., & Teshiba, S. (2000) · Applied Microbiology and Biotechnology · doi:10.1007/s002539900295 · Cited by 68 · see citing works
Transformation of Folate-Consuming Lactobacillus gasseri into a Folate Producer
Wegkamp, A., Starrenburg, M. J. C., de Vos, W. M., Hugenholtz, J., & Sybesma, W. (2004) · Applied and Environmental Microbiology · doi:10.1128/aem.70.5.3146-3148.2004 · Cited by 64 · see citing works
Kneifel, W., Kaufmann, M., Fleischer, A., & Ulberth, F. (1992) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(92)78080-1 · Cited by 56 · see citing works
Folate and Cancer Prevention—Where to Next? Counterpoint
Ulrich, C. M. (2008) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-07-2952 · Cited by 56 · see citing works
Folates in fermented vegetables—a pilot study
Jägerstad, M., Jastrebova, J. A., & Svensson, U. (2004) · LWT · doi:10.1016/j.lwt.2003.11.008 · Cited by 54 · see citing works
Meta‐analysis: folic acid in the chemoprevention of colorectal adenomas and colorectal cancer
Carroll, C., Cooper, K. L., Papaioannou, D. E., Hind, D., Tappenden, P., Pilgrim, H., & Booth, A. (2010) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2010.04238.x · Cited by 49 · see citing works
LeBlanc, J. G., Burgess, C. M., Sesma, F. J. M., de Giori, G. S., & van Sinderen, D. (2005) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(05)73027-7 · Cited by 47 · see citing works
Self-citationB‐Group Vitamins Production by Probiotic Lactic Acid Bacteria
LeBlanc, J. G., Laiño, J., del Valle, M. J., de Giori, G. S., Sesma, F. J. M., & Taranto, M. P. (2015) · doi:10.1002/9781118868386.ch17 · Cited by 46 · see citing works
Self-citationLactobacillus reuteriCRL 1098 prevents side effects produced by a nutritional vitamin B12deficiency
Molina, V. C., Medici, M., Taranto, M. P., & de Valdez, G. F. (2009) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2008.04014.x · Cited by 46 · see citing works
Self-citationGlobal transcriptional response of Lactobacillus reuteri to the sourdough environment
Hüfner, E., Britton, R. A., Roos, S., Jonsson, H., & Hertel, C. (2008) · Systematic and Applied Microbiology · doi:10.1016/j.syapm.2008.06.005 · Cited by 45 · see citing works
Fine-Tuning Our Knowledge of the Anaerobic Route to Cobalamin (Vitamin B 12 )
Roessner, C. A., & Scott, A. I. (2006) · Journal of Bacteriology · doi:10.1128/jb.00918-06 · Cited by 45 · see citing works
Lactococcus lactisis capable of improving the riboflavin status in deficient rats
LeBlanc, J. G., Burgess, C. M., Sesma, F. J. M., et al. (2005) · British Journal Of Nutrition · doi:10.1079/bjn20051473 · Cited by 44 · see citing works
Self-citationbiosynthesis of folates by lactic acid bacteria and propionibacteria in fermented milk
Holasova, M., Fiedlerová, V., Roubal, P., et al. (2004) · Czech Journal of Food Sciences · doi:10.17221/3421-cjfs · Cited by 43 · see citing works
Supplementation with engineered Lactococcus lactis improves the folate status in deficient rats
LeBlanc, J. G., Sybesma, W., Starrenburg, M. J. C., Sesma, F. J. M., de Vos, W. M., de Giori, G. S., & Hugenholtz, J. (2009) · Nutrition · doi:10.1016/j.nut.2009.06.023 · Cited by 42 · see citing works
Self-citationB‐Vitamin Content of Natural Lactic Acid Fermented Cornmeal
Murdock, F. A., & FIELDS, M. L. (1984) · Journal of Food Science · doi:10.1111/j.1365-2621.1984.tb12425.x · Cited by 38 · see citing works
Fermented Milks Fortified with B-group Vitamins: Vitamin Stability and Effect on Resulting Products
Papastoyiannidis, G., Polychroniadou, A., Michaelidou, A.-M., & Alichanidis, E. (2006) · Food Science and Technology International · doi:10.1177/1082013206073274 · Cited by 37 · see citing works
Progress in the field of probiotics: year 2011
Deshpande, G. C., Rao, S., & Patole, S. (2010) · Current Opinion in Gastroenterology · doi:10.1097/mog.0b013e328341373e · Cited by 36 · see citing works
Keck, B., Munder, M., & Renz, P. (1998) · Archives of Microbiology · doi:10.1007/s002030050679 · Cited by 34 · see citing works
Piao, Y., Kiatpapan, P., Yamashita, M., et al. (2004) · Applied and Environmental Microbiology · doi:10.1128/aem.70.12.7561-7566.2004 · Cited by 32 · see citing works
Jayashree, S., Jayaraman, K., & Gurumurthy, K. (2010) · Recent Research in Science and Technology · Cited by 31 · see citing works
Physiological responses to folate overproduction in Lactobacillus plantarum WCFS1
Wegkamp, A., Mars, A. E., Faijes, M., Douwe Molenaar, B., de Vos, R. C. H., Klaus, S. M., Hanson, A. D., de Vos, W. M., & Smid, E. J. (2010) · Microbial Cell Factories · doi:10.1186/1475-2859-9-100 · Cited by 25 · see citing works
Molina, V., Medici, M., Taranto, M. P., et al. (2008) · Archives of Animal Nutrition · doi:10.1080/17450390801892567 · Cited by 24 · see citing works
Self-citationInfluence of a Probiotic Yoghurt on the Status of Vitamins B1, B2 and B6 in the Healthy Adult Human
Elmadfa, I., Heinzle, C., Majchrzak, D., et al. (2001) · Annals of Nutrition and Metabolism · doi:10.1159/000046700 · Cited by 24 · see citing works
LeBlanc, J. G., van Sinderen, D., Hugenholtz, J., Piard, J.-C., Sesma, F. J. M., & de Giori, G. S. (2010) · Current Microbiology · doi:10.1007/s00284-010-9657-7 · Cited by 23 · see citing works
Self-citationB‐Group Vitamins Production by Probiotic Lactic Acid Bacteria
LeBlanc, J. G., Taranto, M. P., Molina, V., & Sesma, F. J. M. (2010) · doi:10.1002/9780813820866.ch12 · Cited by 19 · see citing works
Self-citationPerkins, J. B., & Pero, J. G. (2014) · ASM Press eBooks · doi:10.1128/9781555817992.ch20 · Cited by 19 · see citing works
Finding the final pieces of the vitamin B 12 biosynthetic jigsaw
Warren, M. J. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601030103 · Cited by 18 · see citing works
Trends in U.S. Per Capita Consumption of Dairy Products, 1970-2012
Bentley, J., & Bentley, J. (2014) · RePEc: Research Papers in Economics · doi:10.22004/ag.econ.210933 · Cited by 15 · see citing works
Metabolic engineering of folate production in lactic acid bacteria
Sybesma, W. (2003) · doi:10.18174/121456 · Cited by 13 · see citing works
Vitamin B12Biosynthesis inPseudomonas denitrificans
Thibaut, D., Blanche, F., Cameron, B., Crouzet, J., Debüssche, L., Rémy, E., & Vuilhorgne, M. (1998) · Wiley eBooks · doi:10.1002/9783527612192.ch03 · Cited by 12 · see citing works
Duan, Y., Chen, T., Chen, X., et al. (2010) · Chinese Journal of Chemical Engineering · doi:10.1016/s1004-9541(08)60333-x · Cited by 12 · see citing works
Flagged first, then by citations
Research works printed but not linked: 7
- Neidhardt, F.C., Curtiss, R. III, Ingraham, J.L.L., Lin, E.C.C., Low, K.B., Magasanik, B., Reznikoff, W.S., Riley, M., Schaechter, M. and Umbarger, H.E. pp. 657-664. Washington, DC, USA: ASM Press.
- Macrae, R., Robinson, R.K. and Sadler, M.J. pp. 1936-1944. London, UK: Aca- demic Press.
- Beck, W.S. (2001) Cobalamin (Vitamin B 12 ). In Handbook of Vitamins, 3rd edn ed Rucker, R., Sutie, J., McCormick, D.B. and Machlin, L.J. pp. 463-512. New York: Marcell Dekker.
- Institute of Medicine ed. (1998) Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B 6 , Folate, Vitamin B 12 , Panthothenic Acid, Biotin, and Choline. Washington, DC, USA: National Academies Press.
- Lain ˜o, J., Savoy de Giori, G. and LeBlanc, J.G. (2011) Folate production by lactic acid bacteria. In Bioactive Foods and Supplements in Health Promotion -Liver and Gastrointesti- nal Disease ed. Watson, R. Oxford, UK: Elsevier.
- LeBlanc, J.G., Savoy de Giori, G., Smid, E.J., Hugenholtz, J. and Sesma, F. (2007) Folate production by lactic acid bac- teria and other food-grade microorganisms. In Communi- cating Current Research and Educational Topics and Trends in Applied Microbiology ed. Me ´ndez-Vilas, A. pp. 329-339. Badajoz, Spain: Formatex Research Center.
- Thibaut, D., Blanche, F., Cameron, B., Crouzet, J., Debussche, L., Remy, E. and Vuilhorgne, M. (1998) Vitamin B 12 bio- synthesis in Pseudomonas denitrificans. In Vitamin B 12 and B 12 -Proteins eds Kra ¨utler, B., Arigoni, D. and Golding, B.T. pp. 63-79. Weinheim, Germany: Wiley ⁄ VCH.
Cited by
Sorted by citations
Bacteria as vitamin suppliers to their host: A gut microbiota perspective
LeBlanc, J. G., Milani, C., de Giori, G. S., Sesma, F., van Sinderen, D., & Ventura, M. (2013) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2012.08.005 · Cited by 1,613 · see citing works
Self-citationThe gut microbiota at the intersection of diet and human health
Gentile, C. L., & Weir, T. L. (2018) · Science · doi:10.1126/science.aau5812 · Cited by 1,049 · see citing works
Health benefits of fermented foods
Şanlier, N., Gökcen, B. B., & Sezgin, A. C. (2019) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2017.1383355 · Cited by 789 · see citing works
Fermented Foods as a Dietary Source of Live Organisms
Rezac, S., Kok, C. R., Heermann, M., & Hutkins, R. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01785 · Cited by 540 · see citing works
Microbial imbalance in inflammatory bowel disease patients at different taxonomic levels
Alam, M. T., Amos, G. C. A., Murphy, A. R. J., Murch, S., Wellington, E. M. H., & Arasaradnam, R. P. (2020) · Gut Pathogens · doi:10.1186/s13099-019-0341-6 · Cited by 380 · see citing works
Linares, D. M., Gómez, C., Renes, E., Fresno, J. M., Tornadijo, M. E., Ross, R. P., & Stanton, C. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.00846 · Cited by 335 · see citing works
The food-gut axis: lactic acid bacteria and their link to food, the gut microbiome and human health
De Filippis, F., Pasolli, E., & Ercolini, D. (2020) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuaa015 · Cited by 303 · see citing works
Lactic Acid Bacteria Producing B-Group Vitamins: A Great Potential for Functional Cereals Products
Capozzi, V., Russo, P., Dueñas, M. T., López, P., & Spano, G. (2012) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-012-4440-2 · Cited by 290 · see citing works
Sanders, M. E., Merenstein, D., Merrifield, C. A., & Hutkins, R. (2018) · Nutrition Bulletin · doi:10.1111/nbu.12334 · Cited by 278 · see citing works
Ferrario, C., Taverniti, V., Milani, C., Fiore, W., Laureati, M., De Noni, I., Stuknyte, M., Chouaia, B., Riso, P., & Guglielmetti, S. (2014) · The Journal of Nutrition · doi:10.3945/jn.114.197723 · Cited by 228 · see citing works
Presti, I., D’Orazio, G., Labra, M., La Ferla, B., Mezzasalma, V., Bizzaro, G., Giardina, S., Michelotti, A., Tursi, F., Vassallo, M., et al. (2015) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-015-6482-8 · Cited by 118 · see citing works
Technological properties of lactic acid bacteria isolated from raw cereal material
Salvucci, E., LeBlanc, J. G., & Pérez, G. (2016) · LWT · doi:10.1016/j.lwt.2016.02.043 · Cited by 92 · see citing works
De Giani, A., Bovio, F., Forcella, M., Fusi, P., Sello, G., & Di Gennaro, P. (2019) · AMB Express · doi:10.1186/s13568-019-0813-6 · Cited by 88 · see citing works
Synbiotic in the management of infantile colic: a randomised controlled trial
Kianifar, H., Ahanchian, H., Grover, Z., Jafari, S., Noorbakhsh, Z., Khakshour, A., Sedaghat, M., & Kiani, M. (2014) · Journal of Paediatrics and Child Health · doi:10.1111/jpc.12640 · Cited by 77 · see citing works
Comparative Genomics-Based Probiotic Relevance of Limosilactobacillus fermentum KUB-D18
Phujumpa, P., Muangham, S., Jatuponwiphat, T., Koffas, M., Nakphaichit, M., & Vongsangnak, W. (2022) · Gene · doi:10.1016/j.gene.2022.146747 · Cited by 18 · see citing works
- Authors
- LeBlanc, J. G., Laiño, J. E., del Valle, M. J., Vannini, V., van Sinderen, D., Taranto, M. P., de Valdez, G. F., de Giori, G. S., & Sesma, F.
- Affiliations
- Consejo Nacional de Investigaciones Científicas y Técnicas (AR)
- Venue
- Journal of Applied Microbiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2011-10-10
- Volume
- 111
- Issue
- 6
- Pages
- 1297-1309
- ISSN
- 1364-5072 (ISSN-L)
- OpenAlex
- W1556017534
- Cited by
- 529
- References
- 90
- Citations by year
- 2026: 34 · 2025: 52 · 2024: 57 · 2023: 47 · 2022: 52 · 2021: 44 · 2020: 48 · 2019: 41 · 2018: 43 · 2017: 32 · 2016: 24 · 2015: 22 · 2014: 11 · 2013: 12 · 2012: 9
- FWCI
- 1.43
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Applied Microbiology (publishedVersion)
- PubMed (publishedVersion)
- CONICET Digital (CONICET) (submittedVersion, cc-by-nc-sa)
- Funders
- Science Foundation Ireland (07/CE/B1368)
- Consejo Nacional de Investigaciones Científicas y Técnicas
- Agencia Nacional de Promoción Científica y Tecnológica (CONICET)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Medicine › Rheumatology › Folate and B Vitamins Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
- Keywords
- B vitamins, lactic acid bacteria, vitamin biosynthesis, folic acid, riboflavin, vitamin B12, vitamin deficiency, probiotics, starter cultures, fermented foods, vitamin bioavailability, vitamin fortification, malnutrition
- MeSH terms
- Avitaminosis, Folic Acid, Food, Fortified, Humans, Lactobacillaceae, Riboflavin, Vitamin B Complex, Vitamin B 12, Dietary Supplements, Probiotics
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
