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Long-term effects of early environment on the brain: Lesson from rodent models

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Estrogen in Prefrontal Cortex Blocks Stress-induced Cognitive Impairments in Female Rats

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Neonatal repetitive maternal separation causes long-lasting alterations in various neurotrophic factor expression in the cerebral cortex of rats

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Breed, age, and social environment are associated with personality traits in dogs

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Consequences of early adverse rearing experience(EARE) on development: insights from non-human primate studies.

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Early weaning increases anxiety via brain-derived neurotrophic factor signaling in the mouse prefrontal cortex

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Unstable Maternal Environment Affects Stress Response in Adult Mice in a Genotype-Dependent Manner

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The effect of early life experience, environment, and genetic factors on spontaneous home-cage aggression-related wounding in male C57BL/6 mice

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Partner Loss in Monogamous Rodents: Modulation of Pain and Emotional Behavior in Male Prairie Voles

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Potential Neurodevelopmental Effects of Pediatric Intensive Care Sedation and Analgesia: Repetitive Benzodiazepine and Opioid Exposure Alters Expression of Glial and Synaptic Proteins in Juvenile Rats

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Early Life Stress and the Onset of Obesity: Proof of MicroRNAs’ Involvement Through Modulation of Serotonin and Dopamine Systems’ Homeostasis

Tavares, G. A., Torres, A., & de Souza, J. A. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00925 · Cited by 28 · see citing works

Effects of Early Maternal Separation on Subsequent Reproductive and Behavioral Outcomes in Male Rats

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Early weaning is associated with higher neuropeptide Y (NPY) and lower cocaine- and amphetamine-regulated transcript (CART) expressions in the paraventricular nucleus (PVN) in adulthood

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Prenatal tactile stimulation attenuates drug-induced behavioral sensitization, modifies behavior, and alters brain architecture

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Combined early life stressors: prenatal nicotine and maternal deprivation interact to influence behavioral phenotypes in rats

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Peripheral and central alterations affecting spinal nociceptive processing and pain at adulthood in rats exposed to neonatal maternal deprivation

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Early postnatal repeated maternal deprivation causes a transient increase in OMpg and BDNF in rat cerebellum suggesting precocious myelination

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A dissociation between renewal and contextual fear conditioning in juvenile rats

Park, C. H. J., Ganella, D. E., & Kim, J. H. (2017) · Developmental Psychobiology · doi:10.1002/dev.21516 · Cited by 25 · see citing works

Hyperlocomotor activity and stress vulnerability during adulthood induced by social isolation after early weaning are prevented by voluntary running exercise before normal weaning period

Ishikawa, J., Ogawa, Y., Owada, Y., & Ishikawa, A. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.02.007 · Cited by 24 · see citing works

Neonatal overfeeding by small‐litter rearing sensitises hippocampal microglial responses to immune challenge: Reversal with neonatal repeated injections of saline or minocycline

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Early-Life Neglect Alters Emotional and Cognitive Behavior in a Sex-Dependent Manner and Reduces Glutamatergic Neuronal Excitability in the Prefrontal Cortex

Sun, X., Zhang, Y., Li, X., Liu, X., & Qin, C. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.572224 · Cited by 22 · see citing works

Regulation of corticosterone function during early weaning and effects on gastric cell proliferation

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Maternal separation in mice leads to anxiety-like/aggressive behavior and increases immunoreactivity for glutamic acid decarboxylase and parvalbumin in the adolescence ventral hippocampus

Kim, E.-G., Chang, W., Shin, S., Adhikari, A. S., Seol, G. H., Song, D., & Min, S. S. (2022) · Korean Journal of Physiology and Pharmacology · doi:10.4196/kjpp.2023.27.1.113 · Cited by 21 · see citing works

Ablation of proliferating neural stem cells during early life is sufficient to reduce adult hippocampal neurogenesis

Youssef, M., Krish, V. S., Kirshenbaum, G. S., Atsak, P., Lass, T. J., Lieberman, S. R., Leonardo, E. D., & Dranovsky, A. (2018) · Hippocampus · doi:10.1002/hipo.22962 · Cited by 21 · see citing works

Postnatal steroid therapy is associated with autism spectrum disorder in children and adolescents of very low birth weight infants

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Scientific and Regulatory Policy Committee Review

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Early Life Stress: Consequences for the Development of the Brain

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Early weaning leads to disruption of homeostatic and hedonic eating behaviors and modulates serotonin (5HT) and dopamine (DA) systems in male adult rats

Tavares, G. A., Almeida, L. C. D. A., de Souza, J. A., de Farias, V. V., de Souza, F. L., Silva, S. C. D. A., Lagranha, C. J., Kaeffer, B., & de Souza, S. L. (2020) · Behavioural Brain Research · doi:10.1016/j.bbr.2020.112531 · Cited by 18 · see citing works

Artificially reared mice exhibit anxiety-like behavior in adulthood

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Epigenetik–Revolution der Entwicklungspsychopathologie?

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Terpenoid Backbone Biosynthesis among Pig Hippocampal Pathways Impacted by Stressors

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Low level postnatal methylmercury exposure in vivo alters developmental forms of short-term synaptic plasticity in the visual cortex of rat

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Maternal and offspring methylenetetrahydrofolate‐reductase genotypes interact in a mouse model to induce autism spectrum disorder‐like behavior

Sadigurschi, N., & Golan, H. M. (2018) · Genes Brain & Behavior · doi:10.1111/gbb.12547 · Cited by 16 · see citing works

A novel neurobehavioral framework of the effects of positive early postnatal experience on incentive and consummatory reward sensitivity

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Stress Neurobiology and Developmental Psychopathology

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Perceptual learning deficits mediated by somatostatin releasing inhibitory interneurons of olfactory bulb in an early life stress mouse model

Pardasani, M., Ramakrishnan, A. M., Mahajan, S., Kantroo, M., McGowan, E., Das, S., Srikanth, P., Pandey, S., & Abraham, N. M. (2023) · Molecular Psychiatry · doi:10.1038/s41380-023-02244-3 · Cited by 15 · see citing works

Maternal deprivation alters nociceptive response in a gender‐dependent manner in rats

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Lactobacillus reuteri effects on maternal separation stress in newborn mice

Park, E. S., Freeborn, J., Venna, V. R., Roos, S., Rhoads, J. M., & Liu, Y. (2021) · Pediatric Research · doi:10.1038/s41390-021-01374-0 · Cited by 15 · see citing works

Early postnatal maternal separation causes alterations in the expression of β3-adrenergic receptor in rat adipose tissue suggesting long-term influence on obesity

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Early weaning by maternal prolactin inhibition leads to higher neuropeptide Y and astrogliosis in the hypothalamus of the adult rat offspring

Younes-Rapozo, V., de Moura, E. G., Manhães, A. C., Peixoto‐Silva, N., OLIVEIRA, E. B. D., & Lisboa, P. C. (2015) · British Journal Of Nutrition · doi:10.1017/s0007114514003882 · Cited by 13 · see citing works

Comparison of behavioral characteristics of dogs in the United States and Japan

Nagasawa, M., KANBAYASHI, S., Mogi, K., Serpell, J. A., & Kikusui, T. (2015) · Journal of Veterinary Medical Science · doi:10.1292/jvms.15-0253 · Cited by 13 · see citing works

Basal cortisol concentrations related to maternal behavior during puppy development predict post-growth resilience in dogs

Nagasawa, M., Shibata, Y., Yonezawa, A., Takahashi, T., Kanai, M., Ohtsuka, H., Suenaga, Y., Yabana, Y., Mogi, K., & Kikusui, T. (2021) · Hormones and Behavior · doi:10.1016/j.yhbeh.2021.105055 · Cited by 13 · see citing works

Early weaning impairs a social contagion of pain‐related stretching behavior in mice

Kikusui, T., Ishio, Y., Nagasawa, M., Mogil, J. S., & Mogi, K. (2016) · Developmental Psychobiology · doi:10.1002/dev.21443 · Cited by 12 · see citing works

Post-weaning living with parents during juvenile period alters locomotor activity, social and parental behaviors in mandarin voles

Wu, R., Song, Z., Tai, F., Wang, L., Kong, L., & Wang, J. (2013) · Behavioural Processes · doi:10.1016/j.beproc.2013.05.008 · Cited by 12 · see citing works

Context fear learning and renewal of extinguished fear are dissociated in juvenile female rats

Park, C. H. J., Ganella, D. E., & Kim, J. H. (2019) · Developmental Psychobiology · doi:10.1002/dev.21888 · Cited by 12 · see citing works

Mother recognition and preference after neonatal amygdala lesions in rhesus macaques (Macaca mulatta) raised in a semi‐naturalistic environment

Goursaud, A.-P. S., Wallen, K., & Bachevalier, J. (2014) · Developmental Psychobiology · doi:10.1002/dev.21233 · Cited by 11 · see citing works

Differential Effects of Short- and Long-Term Early Maternal Separation on Subsequent Maternal Behavior in Rats

Bodensteiner, K. J., Ghiraldi, L. L., & Miner, S. S. (2012) · The Journal of General Psychology · doi:10.1080/00221309.2012.661377 · Cited by 11 · see citing works

Breast-Feeding in Infancy and Major Depression in Adulthood: A Retrospective Analysis

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Early weaning influences short-term synaptic plasticity in the medial prefrontal–anterior basolateral amygdala pathway

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Maternal Deprivation and Sex Alter Central Levels of Neurotrophins and Inflammatory Cytokines in Rats Exposed to Palatable Food in Adolescence

Ströher, R., de Oliveira, C., Stein, D. J., de Macedo, I. C., Goularte, J. F., da Silva, L. S., Regner, G. G., Medeiros, H. R., Caumo, W., & Torres, I. L. D. S. (2020) · Neuroscience · doi:10.1016/j.neuroscience.2019.12.027 · Cited by 10 · see citing works

Emotionality-Related Consequences of Early Weaning in Mice and Rats

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Maternal deprivation by early weaning increases corticosterone and decreases hippocampal BDNF and neurogenesis in mice

Kikusui, T. (2009) · Frontiers in Behavioral Neuroscience · doi:10.3389/conf.neuro.08.2009.09.191 · Cited by 2 · see citing works

Early weaning augments neuroendocrine stress responses in mice

Kikusui, T., Nakamura, K., Kakuma, Y., & Mori, Y. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.08.007 · Cited by 82 · see citing works

A review of the behavioral and neurochemical consequences of early weaning in rodents

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Early weaning induces anxiety and aggression in adult mice

Kikusui, T., Takeuchi, Y., & Mori, Y. (2004) · Physiology & Behavior · doi:10.1016/j.physbeh.2003.12.016 · Cited by 103 · see citing works