Long‐term colonic hypersensitivity in adult rats induced by neonatal unpredictable vs predictable shock

Tyler, K.; Moriceau, S.; Sullivan, R. M.; Greenwood‐van Meerveld, B.

doi:10.1111/j.1365-2982.2007.00955.x

Cited by 63Gastrointestinal motility and disordersInfant Health and DevelopmentPsychosomatic Disorders and Their Treatments

Long‐term colonic hypersensitivity in adult rats induced by neonatal unpredictable vs predictable shock

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Tyler, K., Moriceau, S., Sullivan, R. M., Greenwood‐van Meerveld, B.·2007·Neurogastroenterology & Motility

DOI 10.1111/j.1365-2982.2007.00955.xPMC PMC1964755

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Abstract

Our goal was to examine the relationship between early life trauma and the development of visceral hypersensitivity in later life in irritable bowel syndrome (IBS). Rat pups underwent neonatal conditioning: (i) paired odour-shock, where odour is a predictable shock signal, (ii) unpaired odour-shock, where odour is an unpredictable shock signal or (iii) control odour-only with odour presentations and handling without shock. At maturity, colorectal sensitivity was measured as a visceromotor behavioural response. In adulthood, colorectal distension (CRD) induced a pressure-dependent increase in the number of abdominal muscle contractions all three experimental groups. However, compared to animals that had received control odour-only presentations in infancy, there was an attenuated response to CRD in animals previously exposed to neonatal predictable shock pups and an exaggerated response in the animals previously exposed to neonatal unpredictable shock. Adult responses to CRD were altered by infant experience with shock trauma. However, depending on the context of that early life trauma, there are major differences between the long-term effects of that early life trauma on colonic sensitivity compared to controls. These results strengthen the link between early life trauma and adult IBS, and suggest that unpredictable trauma is a critical factor for later life disorders.

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The effects of rough handling and paired odor-shock are not produced when a pup experiences shock without the mother.
“Importantly, these effects are not produced when a pup experiences shock without the mother (Sarro et al., 2014a, Tyler et al., 2007).”
From Early life adversity during the infant sensitive period for attachment: Programming of behavioral neurobiology of threat processing and social behavior (2017) · cites this paper as Tyler et al., 2007

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Minds, brains, and programs
Searle, J. R. (1980) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00005756 · Cited by 6,954 · see citing works
Descending control of pain
Millan, M. J. (2002) · Progress in Neurobiology · doi:10.1016/s0301-0082(02)00009-6 · Cited by 3,035 · see citing works
Pituitary-adrenal and autonomic responses to stress in women after sexual and physical abuse in childhood
Heim, C. (2000) · JAMA · doi:10.1001/jama.284.5.592 · Cited by 1,968 · see citing works
The neurobiological consequences of early stress and childhood maltreatment
Teicher, M. H., Andersen, S. L., Polcari, A., Anderson, C. M., Navalta, C. P., & Kim, D. M. (2003) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(03)00007-1 · Cited by 1,465 · see citing works
Maternal care during infancy regulates the development of neural systems mediating the expression of fearfulness in the rat
Caldji, C., Tannenbaum, B., Sharma, S., Francis, D., Plotsky, P. M., & Meaney, M. J. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.9.5335 · Cited by 1,437 · see citing works
AGA technical review on irritable bowel syndrome.
Drossman, D. A., Camilleri, M., Mayer, E. A., & Whitehead, W. E. (2002) · Gastroenterology · doi:10.1053/gast.2002.37095 · Cited by 1,384 · see citing works
Early adverse experience as a developmental risk factor for later psychopathology: Evidence from rodent and primate models
SÁNCHEZ, M. M., LADD, C. O., & PLOTSKY, P. M. (2001) · Development and Psychopathology · doi:10.1017/s0954579401003029 · Cited by 1,003 · see citing works
Altered rectal perception is a biological marker of patients with irritable bowel syndrome
Mertz, H., Naliboff, B. D., Munakata, J., Niazi, N., & Mayer, E. A. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90267-8 · Cited by 976 · see citing works
Basic and clinical aspects of visceral hyperalgesia
Mayer, E. A., & Gebhart, G. F. (1994) · Gastroenterology · doi:10.1016/0016-5085(94)90086-8 · Cited by 920 · see citing works
Sexual and physical abuse in women with functional or organic gastrointestinal disorders
Drossman, D. A., Leserman, J., Nachman, G., Li, Z., Gluck, H., Toomey, T. C., & Mitchell, C. M. (1990) · Annals of Internal Medicine · doi:10.7326/0003-4819-113-11-828 · Cited by 898 · see citing works
Handbook of developmental cognitive neuroscience
O’Connor, T. G. (2002) · Attachment & Human Development · Cited by 873 · see citing works
Pain from distension of the pelvic colon by inflating a balloon in the irritable colon syndrome
Ritchie, J. (1973) · Gut · doi:10.1136/gut.14.2.125 · Cited by 832 · see citing works
Colorectal distension as a noxious visceral stimulus: physiologic and pharmacologic characterization of pseudaffective reflexes in the rat
Ness, T. J., & Gebhart, G. F. (1988) · Brain Research · doi:10.1016/0006-8993(88)91555-7 · Cited by 658 · see citing works
Persistent elevations of cerebrospinal fluid concentrations of corticotropin-releasing factor in adult nonhuman primates exposed to early-life stressors: implications for the pathophysiology of mood and anxiety disorders.
Coplan, J. D., Andrews, M. W., Rosenblum, L. A., Owens, M. J., Friedman, S., Gorman, J. M., & Nemeroff, C. B. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.4.1619 · Cited by 649 · see citing works
The Effects of Early Rearing Environment on the Development of GABAA and Central Benzodiazepine Receptor Levels and Novelty-Induced Fearfulness in the Rat
Caldji, C. (2000) · Neuropsychopharmacology · doi:10.1016/s0893-133x(99)00110-4 · Cited by 606 · see citing works
Tolerance for Rectosigmoid Distention in Irritable Bowel Syndrome
Whitehead, W. E., Holtkötter, B., Enck, P., Hoelzl, R., Holmes, K. D., Anthony, J. C., Shabsin, H. S., & Schuster, M. M. (1990) · Gastroenterology · doi:10.1016/0016-5085(90)90332-u · Cited by 592 · see citing works
The Affectional Systems
Harlow, H. F., & Harlow, M. K. (1965) · Elsevier eBooks · doi:10.1016/b978-1-4832-2821-1.50008-2 · Cited by 564 · see citing works
Importance of studying the contributions of early adverse experience to neurobiological findings in depression
Heim, C., Plotsky, P. M., & Nemeroff, C. B. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300397 · Cited by 514 · see citing works
The Battered Child
Helfer, R. E., & Kempe, C. H. (1974) · Medical Entomology and Zoology · Cited by 496 · see citing works
Neonatal maternal separation alters stress-induced responses to viscerosomatic nociceptive stimuli in rat
Coutinho, S. V., Plotsky, P. M., Sablad, M., Miller, J. C., Zhou, H., Bayati, A. I., McRoberts, J. A., & Mayer, E. A. (2002) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00240.2001 · Cited by 456 · see citing works
V. Stress and irritable bowel syndrome
Mayer, E. A., Naliboff, B. D., Chang, L., & Coutinho, S. V. (2001) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.2001.280.4.g519 · Cited by 413 · see citing works
Maternal presence serves as a switch between learning fear and attraction in infancy
Moriceau, S., & Sullivan, R. M. (2006) · Nature Neuroscience · doi:10.1038/nn1733 · Cited by 386 · see citing works
Self-citation
Somatic Effects of Predictable and Unpredictable Shock
Weiss, J. M. (1970) · Psychosomatic Medicine · doi:10.1097/00006842-197007000-00008 · Cited by 357 · see citing works
Gastrointestinal tract symptoms and self-reported abuse: A population-based study
Talley, N. J., Fett, S. L., ZINSMEISTER, A. R., & Melton, L. J. (1994) · Gastroenterology · doi:10.1016/0016-5085(94)90228-3 · Cited by 355 · see citing works
Corticosterone delivery to the amygdala increases corticotropin-releasing factor mRNA in the central amygdaloid nucleus and anxiety-like behavior
Shepard, J. D., Barron, K. W., & Myers, D. A. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02019-9 · Cited by 321 · see citing works
Pavlovian conditioning of rat mucosal mast cells to secrete rat mast cell protease II
MacQueen, G., Marshall, J., Perdue, M., Siegel, S., & Bienenstock, J. (1989) · Science · doi:10.1126/science.2911721 · Cited by 318 · see citing works
Maternal Deprivation Effect on the Infant’s Neural Stress Markers Is Reversed by Tactile Stimulation and Feeding But Not by Suppressing Corticosterone
van Oers, H. J. J., de Kloet, E. R., Whelan, T., & Levine, S. D. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-23-10171.1998 · Cited by 284 · see citing works
Toward a general theory of infantile attachment: a comparative review of aspects of the social bond
Rajecki, D. W., Lamb, M. E., & Obmascher, P. (1978) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00075816 · Cited by 266 · see citing works
Evidence for exacerbation of irritable bowel syndrome during menses
Whitehead, W. E., Cheskin, L. J., Heller, B. R., Robinson, J. C., Crowell, M. D., Benjamin, C., & Schuster, M. M. (1990) · Gastroenterology · doi:10.1016/0016-5085(90)91079-l · Cited by 262 · see citing works
Neonatal maternal separation predisposes adult rats to colonic barrier dysfunction in response to mild stress
Söderholm, J. D., Yates, D. A., Gareau, M. G., Yang, P.-C., MacQueen, G., & Perdue, M. H. (2002) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00314.2002 · Cited by 243 · see citing works
Neonatal maternal deprivation triggers long term alterations in colonic epithelial barrier and mucosal immunity in rats
Barreau, F., Ferrier, L., Fioramonti, J., & Bueno, L. P. (2004) · Gut · doi:10.1136/gut.2003.024174 · Cited by 240 · see citing works
Dual Circuitry for Odor-Shock Conditioning during Infancy: Corticosterone Switches between Fear and Attraction via Amygdala
Moriceau, S., Wilson, D. A., Levine, S. D., & Sullivan, R. M. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.0499-06.2006 · Cited by 240 · see citing works
Self-citation
Altered pain perception and psychosocial features among women with gastrointestinal disorders and history of abuse: A preliminary model
Scarinci, I. C., McDonald-Haile, J., Bradley, L. A., & Richter, J. E. (1994) · The American Journal of Medicine · doi:10.1016/0002-9343(94)90020-5 · Cited by 230 · see citing works
The Effects of Early Shock and Handling on Later Avoidance Learning1
Levine, S., Chevalier, J. A., & Korchin, S. J. (1956) · Journal of Personality · doi:10.1111/j.1467-6494.1956.tb01283.x · Cited by 206 · see citing works
Physiological correlates of childhood abuse: chronic hyperarousal in PTSD, depression, and irritable bowel syndrome
Kendall-Tackett, K. A. (2000) · Child Abuse & Neglect · doi:10.1016/s0145-2134(00)00136-8 · Cited by 192 · see citing works
Corticotropin‐Releasing Factor and the Brain‐Gut Motor Response to Stress
Taché, Y., Martı́nez, V., Million, M., & Rivier, J. (1999) · Canadian Journal of Gastroenterology and Hepatology · doi:10.1155/1999/375916 · Cited by 177 · see citing works
Early life stress impairs fear conditioning in adult male and female rats
Kosten, T. A., Lee, H. J., & Kim, J. J. (2006) · Brain Research · doi:10.1016/j.brainres.2006.03.009 · Cited by 170 · see citing works
Do psychosocial factors define symptom severity and patient status in irritable bowel syndrome?
Drossman, D. A. (1999) · The American Journal of Medicine · doi:10.1016/s0002-9343(99)00081-9 · Cited by 168 · see citing works
Brain Circuits Involved in Corticotropin‐Releasing Factor‐Norepinephrine Interactions during Stress
DUNN, A. J., SWIERGIEL, A. H., & PALAMARCHOUK, V (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1296.003 · Cited by 155 · see citing works
Self-reported abuse and gastrointestinal disease in outpatients: association with irritable bowel-type symptoms.
Talley, N. J., Fett, S. L., & Zinsmeister, A. R. (1995) · PubMed · Cited by 152 · see citing works
Diagnosis of irritable bowel syndrome
Olden, K. W. (2002) · Gastroenterology · doi:10.1053/gast.2002.33741 · Cited by 152 · see citing works
Recollection of Childhood Events in Adults with Irritable Bowel Syndrome
Lowman, B., Drossman, D. A., Cramer, E. M., & McKee, D. C. (1987) · Journal of Clinical Gastroenterology · doi:10.1097/00004836-198706000-00017 · Cited by 146 · see citing works
Pathways involved in gut mucosal barrier dysfunction induced in adult rats by maternal deprivation: corticotrophin‐releasing factor and nerve growth factor interplay
Barreau, F., Cartier, C., Leveque, M., Ferrier, L., Moriez, R., Laroute, V., Rosztoczy, A. I., Fioramonti, J., & Bueno, L. P. (2007) · The Journal of Physiology · doi:10.1113/jphysiol.2006.120907 · Cited by 144 · see citing works
Corticotropin releasing factor mRNA expression in the hypothalamic paraventricular nucleus and the central nucleus of the amygdala is modulated by repeated acute stress in the immature rat
Hatalski, C. G., Guirguis, C., & Baram, T. Z. (1998) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.1998.00246.x · Cited by 132 · see citing works
The effects of prenatal exposure to predictable or unpredictable stress on early development in the rat
Freide, E., & Weinstock, M. (1984) · Developmental Psychobiology · doi:10.1002/dev.420170607 · Cited by 131 · see citing works
Calcitonin gene-related peptide in viscerosensitive response to colorectal distension in rats
Plourde, V., St‐Pierre, S., & Quirion, R. (1997) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.1997.273.1.g191 · Cited by 129 · see citing works
Stereotaxic delivery of corticosterone to the amygdala modulates colonic sensitivity in rats
Meerveld, B. G., Gibson, M. S., Gunter, W., Shepard, J. D., Foreman, R. D., & Myers, D. A. (2001) · Brain Research · doi:10.1016/s0006-8993(00)03305-9 · Cited by 125 · see citing works
Toward a Neurobiology of Attachment
Insel, T. R. (2000) · Review of General Psychology · doi:10.1037/1089-2680.4.2.176 · Cited by 122 · see citing works
Evidence for visceral hypersensitivity in high-anxiety rats
Gunter, W., Shepard, J. D., Foreman, R. D., Myers, D. A., & Beverley (2000) · Physiology & Behavior · doi:10.1016/s0031-9384(99)00254-1 · Cited by 121 · see citing works
Persistent central nervous system effects of an adverse early environment: Clinical and preclinical studies
Gutman, D. A., & Nemeroff, C. B. (2003) · Physiology & Behavior · doi:10.1016/s0031-9384(03)00166-5 · Cited by 115 · see citing works
Abuse, Dissociation, and Somatization in Irritable Bowel Syndrome: Towards an Explanatory Model
Salmon, P., Skaife, K., & Rhodes, J. M. (2003) · Journal of Behavioral Medicine · doi:10.1023/a:1021718304633 · Cited by 107 · see citing works
Commentary: Is maternal stimulation the mediator of the handling effect in infancy?
Denenberg, V. H. (1999) · Developmental Psychobiology · doi:10.1002/(sici)1098-2302(199901)34:1 · Cited by 107 · see citing works
Corticotropin-releasing factor receptor 1 mediates acute and delayed stress-induced visceral hyperalgesia in maternally separated Long-Evans rats
Schwetz, I., McRoberts, J. A., Coutinho, S. V., Bradesi, S., Gale, G. D., Fanselow, M. S., Million, M., Ohning, G., Taché, Y., Plotsky, P. M., et al. (2005) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00498.2004 · Cited by 106 · see citing works
Early Experience Modifies the Postnatal Assembly of Autonomic Emotional Motor Circuits in Rats
Card, J. P., Levitt, P. R., Gluhovsky, M. Y., & Rinaman, L. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.2345-05.2005 · Cited by 97 · see citing works
Influence of sex and experimental protocol on the effect of maternal deprivation on rectal sensitivity to distension in the adult rat
Rosztoczy, A. I., Fioramonti, J., Jármay, K., Barreau, F., Wittmann, T., & Bueno, L. P. (2003) · Neurogastroenterology & Motility · doi:10.1046/j.1350-1925.2003.00451.x · Cited by 91 · see citing works
Chronic fear and ulcers in rats as a function of the unpredictability of safety.
Seligman, M. E., & Meyer, B. (1970) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0030219 · Cited by 90 · see citing works
Psychosocial aspects of assessment and treatment of irritable bowel syndrome in adults and recurrent abdominal pain in children.
Blanchard, E. B., & Scharff, L. (2002) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.70.3.725 · Cited by 88 · see citing works
Corticosterone Influences on Mammalian Neonatal Sensitive-Period Learning.
Moriceau, S., & Sullivan, R. M. (2004) · Behavioral Neuroscience · doi:10.1037/0735-7044.118.2.274 · Cited by 87 · see citing works
Self-citation
Modification of Social Memory, Hypothalamic-Pituitary-Adrenal Axis, and Brain Asymmetry by Neonatal Novelty Exposure
Tang, A. C., Reeb, B. C., Romeo, R. D., & McEwen, B. S. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-23-08254.2003 · Cited by 78 · see citing works
Emotional Stress and Characteristics of Brain Noradrenaline Release in the Rat.
Tanaka, M. (1999) · Industrial Health · doi:10.2486/indhealth.37.143 · Cited by 71 · see citing works
Corticosterone implants to the amygdala and type 1 CRH receptor regulation: Effects on behavior and colonic sensitivity
Myers, D. A., Gibson, M. S., Schulkin, J. A., & van-Meerveld, B. G. (2005) · Behavioural Brain Research · doi:10.1016/j.bbr.2005.03.001 · Cited by 69 · see citing works
Psychosocial aspects of assessment and treatment of irritable bowel syndrome in adults and recurrent abdominal pain in children.
Blanchard, E. B., & Scharff, L. (2002) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.70.3.725 · Cited by 60 · see citing works
Early Maternal Separation Increases Gastric Ulcer Risk in Rats by Producing a Latent Thermoregulatory Disturbance
Ackerman, S. H., Hofer, M. A., & Weiner, H. (1978) · Science · doi:10.1126/science.566471 · Cited by 59 · see citing works
Activation of peripheral 5‐HT4receptors attenuates colonic sensitivity to intraluminal distension
Meerveld, B. G., Venkova, K. M., Hicks, G. A., Dennis, E., & Crowell, M. D. (2005) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2005.00723.x · Cited by 59 · see citing works
Pavlovian conditioning of nasal tryptase release in human subjects with allergic rhinitis
Gauci, M., Husband, A. J., Saxarra, H., & King, M. G. (1994) · Physiology & Behavior · doi:10.1016/0031-9384(94)90066-3 · Cited by 59 · see citing works
Stressor predictability and rat brain noradrenaline metabolism
Tsuda, A., Ida, Y., Satoh, H., Tsujimaru, S., & Tanaka, M. (1989) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(89)90198-6 · Cited by 57 · see citing works
Stress, Inflammation and the Irritable Bowel Syndrome
Collins, S. M., Barbara, G., & Vallance, B. A. (1999) · Canadian Journal of Gastroenterology and Hepatology · doi:10.1155/1999/916075 · Cited by 55 · see citing works
The role of psychosocial factors in irritable bowel syndrome
Gaynes, B. N., & Drossman, D. A. (1999) · Best Practice & Research Clinical Gastroenterology · doi:10.1053/bega.1999.0038 · Cited by 48 · see citing works
The effects of postnatal maternal separation on stress responsivity and experimentally induced colitis in adult rats
Milde, A. M., Enger, Ø., & Murison, R. C. C. (2004) · Physiology & Behavior · doi:10.1016/j.physbeh.2004.01.002 · Cited by 46 · see citing works
Passive avoidance learning in the young rat
Blozovski, D., & Cudennec, A. (1980) · Developmental Psychobiology · doi:10.1002/dev.420130510 · Cited by 46 · see citing works
Inhibitory learning and memory in newborn rats
Mysliveček, J. (1997) · Progress in Neurobiology · doi:10.1016/s0301-0082(97)00036-1 · Cited by 42 · see citing works
Corticosterone Acts Directly at the Amygdala to Alter Spinal Neuronal Activity in Response to Colorectal Distension
Qin, C., Meerveld, B. G., Myers, D. A., & Foreman, R. D. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00834.2002 · Cited by 41 · see citing works
Response heterogeneity of 5-HT3 receptor antagonists in a rat visceral hypersensitivity model
Langlois, A., Pascaud, X., Junien, J., Dahl, S. G., & Rivière, P. J.-M. (1996) · European Journal of Pharmacology · doi:10.1016/s0014-2999(96)00857-6 · Cited by 36 · see citing works
Social factors affecting emotionality and resistance to disease in animals: III. Early weaning and susceptibility to gastric ulcers in the rat. A control for nutritional factors.
Ader, R. (1962) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0041164 · Cited by 32 · see citing works
5‐HT2B receptors do not modulate sensitivity to colonic distension in rats with acute colorectal hypersensitivity
Meerveld, B. G., Campbell-Dittmeyer, K. M., Johnson, A. C., et al. (2006) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2006.00767.x · Cited by 13 · see citing works

Flagged first, then by citations

Research works printed but not linked: 2

[56]Salzen EA. Imprinting and environmental learning. In: Aronson LR, Tobach E, Lehrman DS, Rosensblatt J, editors. Development and Evolution of Behavior. W.H. Freeman; San Francisco: 1970. Chapter in book. [Google Scholar]
[58]Maestripieri D, Tomaszycki M, Carroll KA. Consistency and change in the behavior of rhesus macaque abusive mothers with successive infants. Dev Psychobiol. 1999;34:29–35. [PubMed] [Google Scholar]

Sorted by citations

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O'Mahony, S. M., Marchesi, J. R., Scully, P., Codling, C., Ceolho, A.-M., Quigley, E. M. M., Cryan, J. F., & Dinan, T. G. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.06.026 · Cited by 1,069 · see citing works
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Authors: Tyler, K., Moriceau, S., Sullivan, R. M., & Greenwood‐van Meerveld, B.
Affiliations: Oklahoma City VA Medical Center (US)
University of Oklahoma (US)
ORCID: Moriceau, S.
Sullivan, R. M.
Venue: Neurogastroenterology & Motility
Publisher: Wiley
Published: 2007-07-18
Volume: 19
Issue: 9
Pages: 761-768
ISSN: 1350-1925 (ISSN-L)
1365-2982
DOI: 10.1111/j.1365-2982.2007.00955.x
PMC: PMC1964755
OpenAlex: W2021380158
Cited by: 63
References: 75
Citations by year: 2026: 1 · 2024: 1 · 2023: 2 · 2021: 2 · 2020: 1 · 2019: 3 · 2018: 3 · 2017: 2 · 2016: 9 · 2015: 3 · 2014: 5 · 2013: 8 · 2012: 5
FWCI: 4.82
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Neurogastroenterology & Motility (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health
Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD33402, R01HD033402)
Topics: Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Health Sciences › Health Professions › Pharmacy › Infant Health and Development
Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
Keywords: irritable bowel syndrome, early trauma, visceral hypersensitivity, colorectal distension, visceromotor response, abdominal muscle contraction
MeSH terms: Animals, Animals, Newborn, Conditioning, Classical, Fear, Female, Hyperalgesia, Male, Manometry, Odorants, Stress, Psychological, Time Factors, Irritable Bowel Syndrome, Rats

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Long‐term colonic hypersensitivity in adult rats induced by neonatal unpredictable vs predictable shock

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