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Cited by 1,184

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Review: Ultraviolet radiation and skin cancer

Narayanan, Deevya L., Saladi, Rao N., Fox, Joshua L.·2010·International Journal of Dermatology

Abstract

Skin cancer is the most common type of cancer in fair‐skinned populations in many parts of the world. The incidence, morbidity and mortality rates of skin cancers are increasing and, therefore, pose a significant public health concern. Ultraviolet radiation (UVR) is the major etiologic agent in the development of skin cancers. UVR causes DNA damage and genetic mutations, which subsequently lead to skin cancer. A clearer understanding of UVR is crucial in the prevention of skin cancer. This article reviews UVR, its damaging effects on the skin and its relationship to UV immunosuppression and skin cancer. Several factors influence the amount of UVR reaching the earth’s surface, including ozone depletion, UV light elevation, latitude, altitude, and weather conditions. The current treatment modalities utilizing UVR (i.e. phototherapy) can also predispose to skin cancers. Unnecessary exposure to the sun and artificial UVR (tanning lamps) are important personal attributable risks. This article aims to provide a comprehensive overview of skin cancer with an emphasis on carefully evaluated statistics, the epidemiology of UVR‐induced skin cancers, incidence rates, risk factors, and preventative behaviors & strategies, including personal behavioral modifications and public educational initiatives.

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Crossref · 10.1111/j.1365-4632.2010.04474.x

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Metadata

Authors
Narayanan, D. L., Saladi, R. N., & Fox, J. L.
Venue
International Journal of Dermatology
Publisher
Wiley
Published
2010-08-30
Volume
49
Issue
9
Pages
978-986
ISSN
  • 0011-9059 (ISSN-L)
  • 1365-4632
OpenAlex
W1540044642
Cited by
1,184
References
5
FWCI
39.91
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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