Cytokines and schizophrenia: microglia hypothesis of schizophrenia

Cytokines sing the blues: inflammation and the pathogenesis of depression

Raison, C. L., Capuron, L., & Miller, A. H. (2006) · Trends in Immunology · doi:10.1016/j.it.2005.11.006 · Cited by 3,009 · see citing works

Inflammatory Blockade Restores Adult Hippocampal Neurogenesis

Monje, M. L., Toda, H., & Palmer, T. D. (2003) · Science · doi:10.1126/science.1088417 · Cited by 2,426 · see citing works

Inflammation is detrimental for neurogenesis in adult brain

Ekdahl, C. T., Claasen, J.-H., Bonde, S., Kokaia, Z., & Lindvall, O. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2234031100 · Cited by 1,559 · see citing works

Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism

Block, M. L., & Hong, J.-S. (2005) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2005.06.004 · Cited by 1,557 · see citing works

Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial

Tyring, S., Gottlieb, A., Papp, K., Gordon, K., Leonardi, C., Wang, A., Lalla, D., Woolley, M., Jahreis, A., Zitnik, R., et al. (2006) · The Lancet · doi:10.1016/s0140-6736(05)67763-x · Cited by 1,069 · see citing works

White Matter Changes in Schizophrenia: Evidence for Myelin-Related Dysfunction

Davis, K. L., Stewart, D. G., Friedman, J. I., Buchsbaum, M., Harvey, P. D., Hof, P. R., Buxbaum, J., & Haroutunian, V. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.5.443 · Cited by 793 · see citing works

Neural stem cell proliferation is decreased in schizophrenia, but not in depression

Reif, A., Fritzen, S., Finger, M., Strobel, A., Lauer, M., Schmitt, A., & Lesch, K.-P. (2006) · Molecular Psychiatry · doi:10.1038/sj.mp.4001791 · Cited by 630 · see citing works

Evidence for activation of microglia in patients with psychiatric illnesses

Bayer, T. A., Buslei, R., Havas, L., & Falkai, P. (1999) · Neuroscience Letters · doi:10.1016/s0304-3940(99)00545-5 · Cited by 323 · see citing works

Minocycline as Adjunctive Therapy for Schizophrenia: An Open-Label Study

Miyaoka, T., Yasukawa, R., Yasuda, H., Hayashida, M., Inagaki, T., & Horiguchi, J. (2008) · Clinical Neuropharmacology · doi:10.1097/wnf.0b013e3181593d45 · Cited by 146 · see citing works

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

Schafer, D. P., Lehrman, E. K., Kautzman, A. G., Koyama, R., Mardinly, A. R., Yamasaki, R., Ransohoff, R. M., Greenberg, M. E., Barres, B. A., & Stevens, B. (2012) · Neuron · doi:10.1016/j.neuron.2012.03.026 · Cited by 4,089 · see citing works

Meta-Analysis of Cytokine Alterations in Schizophrenia: Clinical Status and Antipsychotic Effects

Miller, B. J., Buckley, P., Seabolt, W., Mellor, A., & Kirkpatrick, B. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.04.013 · Cited by 1,742 · see citing works

The Complement System: An Unexpected Role in Synaptic Pruning During Development and Disease

Stephan, A. H., Barres, B. A., & Stevens, B. (2012) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-061010-113810 · Cited by 1,113 · see citing works

The role of inflammation and microglial activation in the pathophysiology of psychiatric disorders

Réus, G. Z., Fries, G. R., Stertz, L., Badawy, M., Passos, I. C., Barichello, T., Kapczinski, F., & Quevedo, J. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.05.018 · Cited by 594 · see citing works

The “quad‐partite” synapse: Microglia‐synapse interactions in the developing and mature CNS

Schafer, D. P., Lehrman, E. K., & Stevens, B. (2013) · Glia · doi:10.1002/glia.22389 · Cited by 570 · see citing works

Cytokine function in medication-naive first episode psychosis: A systematic review and meta-analysis

Upthegrove, R., Manzanares-Teson, N., & Barnes, N. M. (2014) · Schizophrenia Research · doi:10.1016/j.schres.2014.03.005 · Cited by 501 · see citing works

Meta-analysis of oxidative stress in schizophrenia.

Flatow, J., Buckley, P., & Miller, B. J. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.03.018 · Cited by 491 · see citing works

Microglia Function in Central Nervous System Development and Plasticity

Schafer, D. P., & Stevens, B. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a020545 · Cited by 353 · see citing works

<i>Hikikomori</i>  : Multidimensional understanding, assessment, and future international perspectives

Kato, T. A., Kanba, S., & Teo, A. R. (2019) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.12895 · Cited by 335 · see citing works

The methodology of TSPO imaging with positron emission tomography

Turkheimer, F. E., Rizzo, G., Bloomfield, P. S., Howes, O., Zanotti-Fregonara, P., Bertoldo, A., & Veronese, M. (2015) · Biochemical Society Transactions · doi:10.1042/bst20150058 · Cited by 238 · see citing works

Novel roles for immune molecules in neural development: implications for neurodevelopmental disorders

Garay, P. (2010) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2010.00136 · Cited by 217 · see citing works

Nanoscale Surveillance of the Brain by Microglia via cAMP-Regulated Filopodia

Bernier, L.-P., Bohlen, C. J., York, E. M., Choi, H. B., Kamyabi, A., Dissing-Olesen, L., Hefendehl, J. K., Collins, H. Y., Stevens, B., Barres, B. A., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.05.010 · Cited by 211 · see citing works

Functional diversity of microglia – how heterogeneous are they to begin with?

Hanisch, U.-K. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00065 · Cited by 195 · see citing works

Suicide and Microglia: Recent Findings and Future Perspectives Based on Human Studies

Suzuki, H., Ohgidani, M., Kuwano, N., Chrétien, F., Lorin de la Grandmaison, G., Onaya, M., Tominaga, I., Setoyama, D., Kang, D., Mimura, M., et al. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00031 · Cited by 198 · see citing works

Extensive white matter abnormalities in patients with first-episode schizophrenia: a diffusion tensor imaging (DTI) study

Lee, S.-H., Kubicki, M., Asami, T., Seidman, L. J., Goldstein, J. M., Mesholam-Gately, R. I., McCarley, R. W., & Shenton, M. E. (2013) · Schizophrenia Research · doi:10.1016/j.schres.2012.11.029 · Cited by 176 · see citing works

Maternal immune activation in neurodevelopmental disorders

Solek, C. M., Farooqi, N., Verly, M., Lim, T. K., & Ruthazer, E. S. (2018) · Developmental Dynamics · doi:10.1002/dvdy.24612 · Cited by 168 · see citing works

Acute variations of cytokine levels after antipsychotic treatment in drug-naïve subjects with a first-episode psychosis: A meta-analysis

Capuzzi, E., Bartoli, F., Crocamo, C., Clerici, M., & Carrà, G. (2017) · Neuroscience &amp; Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.03.003 · Cited by 139 · see citing works

Redox Dysregulation in the Pathophysiology of Schizophrenia and Bipolar Disorder: Insights from Animal Models

Kulak, A., Steullet, P., Cabungcal, J.-H., Werge, T., Ingason, A., Cuenod, M., & Do, K. Q. (2013) · Antioxidants &amp; Redox Signaling · doi:10.1089/ars.2012.4858 · Cited by 124 · see citing works

Reduced white matter integrity and cognitive deficit in never-medicated chronic schizophrenia: A diffusion tensor study using TBSS

Liu, X., Lai, Y., Wang, X., Hao, C., Chen, L., Zhou, Z., Yu, X., & Hong, N. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.05.061 · Cited by 101 · see citing works

Perineuronal nets and schizophrenia: The importance of neuronal coatings

Bitanihirwe, B. K. Y., & Woo, T.-U. W. (2014) · Neuroscience &amp; Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.03.018 · Cited by 95 · see citing works

Tryptophan-kynurenine and lipid related metabolites as blood biomarkers for first-episode drug-naïve patients with major depressive disorder: An exploratory pilot case-control study

Kuwano, N., Kato, T. A., Setoyama, D., Sato-Kasai, M., Shimokawa, N., Hayakawa, K., Ohgidani, M., Sagata, N., Kubo, H., Kishimoto, J., et al. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.01.014 · Cited by 69 · see citing works

<i>Fosb</i>gene products contribute to excitotoxic microglial activation by regulating the expression of complement C5a receptors in microglia: <i>Fosb</i>Regulates Expression of C5a Receptors

Nomaru, H., Sakumi, K., Katogi, A., Ohnishi, Y. N., Kajitani, K., Tsuchimoto, D., Nestler, E. J., & Nakabeppu, Y. (2014) · Glia · doi:10.1002/glia.22680 · Cited by 68 · see citing works

Comparison of the anti-inflammatory effect of aripiprazole and risperidone in 75 drug-naïve first episode psychosis individuals: A 3 months randomized study

Juncal-Ruiz, M., Riesco-Dávila, L., Ortiz-García de la Foz, V., Martínez-Garcia, O., Ramírez-Bonilla, M., Ocejo-Viñals, J. G., Leza, J. C., López-Hoyos, M., & Crespo-Facorro, B. (2018) · Schizophrenia Research · doi:10.1016/j.schres.2018.06.039 · Cited by 55 · see citing works

Exercise prevents downregulation of hippocampal presynaptic proteins following olanzapine-elicited metabolic dysregulation in rats: distinct roles of inhibitory and excitatory terminals.

Ramos-Miguel, A., Honer, W. G., Boyda, H. N., Sawada, K., Beasley, C. L., Procyshyn, R. M., & Barr, A. M. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.06.022 · Cited by 18 · see citing works

Review of Standard Laboratory Blood Parameters in Patients with Schizophrenia and Bipolar Disorder

Serdarevic, A., Ristic, L., Sulejmanpasic, G., Tahirovic, A., Valjevac, A., & Lazovic, E. (2020) · Medical Archives · doi:10.5455/medarh.2020.74.374-380 · Cited by 12 · see citing works