Selective behavioral and neurochemical effects of cholinergic lesions produced by intrabasalis infusions of 192 IgG-saporin on attentional performance in a five-choice serial reaction time task
Open accessAbstract
The effects of the cholinergic immunotoxin 192 IgG-saporin (SAP) (0.0, 0.15, or 0.45 microg/microl; 0.5 microl/hemisphere) infused into the area of the nucleus basalis magnocellularis (NBM) of rats were tested in a five-choice serial reaction time task (5CSRTT) designed to assess visual attention. The effects of this manipulation on acetylcholine efflux in the medial frontal cortex were determined using in vivo microdialysis during the 5CSRTT. Rats with extensive lesions of the NBM (SAP HIGH) showed an array of behavioral deficits in the 5CSRTT hypothesized to represent deficits in central executive function that were associated with severe deficits in accuracy. Lengthening the stimulus duration ameliorated these deficits. Rats with restricted lesions of the NBM (SAP LOW) showed impairments over time on task when tested under standard conditions that were exacerbated by increases in the event rate. The number of choline acetyltransferase-immunoreactive cells in the area of the NBM but not the vertical limb of the diagonal band correlated significantly with accuracy in the task. SAP HIGH rats had significantly lower levels of cortical acetylcholine (ACh) efflux relative to SHAM both before and during the 5CSRTT. SAP LOW rats showed significantly higher levels of cortical ACh efflux before but not during the 5CSRTT. Cortical ACh efflux increased in all rats with the onset of the attentional task. These data provide the first direct evidence for a relationship between selective damage in the basal forebrain with decreased cortical ACh efflux and impaired attentional function.
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In rodents, lesions of cholinergic inputs to the cortex impair tests of sustained attention, particularly across sensory modalities.
“In rodents, lesions of cholinergic inputs to the cortex impair tests of sustained attention, particularly across sensory modalities (McGaughy et al., 2002; McGaughy et al., 1996; Turchi and Sarter, 1997).”
From Acetylcholine as a Neuromodulator: Cholinergic Signaling Shapes Nervous System Function and Behavior (2012) · cites this paper as McGaughy et al., 2002
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Cites
The rat brain in stereotaxic coordinates
Palkovits, M. (1983) · Neuropeptides · doi:10.1016/0143-4179(83)90049-5 · Cited by 28,959 · see citing works
The Rat Brain in Stereotaxic Coordinates
Paxinos, G., & Watson, C. (1983) · Elsevier eBooks · doi:10.1016/c2009-0-63235-9 · Cited by 28,585 · see citing works
AChE-stained horizontal sections of the rat brain in stereotaxic coordinates
Paxinos, G., WATSON, C. R. R., & Emson, P. C. (1980) · Journal of Neuroscience Methods · doi:10.1016/0165-0270(80)90021-7 · Cited by 4,501 · see citing works
Central cholinergic pathways in the rat: An overview based on an alternative nomenclature (Ch1–Ch6)
Mesulam, M. M., Mufson, E. J., Wainer, B. H., & Levey, A. I. (1983) · Neuroscience · doi:10.1016/0306-4522(83)90108-2 · Cited by 2,329 · see citing works
Mesulam, M. ‐., Mufson, E. J., Levey, A. I., & Wainer, B. H. (1983) · Journal of Comparative Neurology · doi:10.1002/cne.902140206 · Cited by 1,962 · see citing works
CENTRAL CHOLINERGIC SYSTEMS AND COGNITION
Everitt, B. J., & Robbins, T. W. (1997) · Annual Review of Psychology · doi:10.1146/annurev.psych.48.1.649 · Cited by 1,348 · see citing works
Self-citationCoull, J. T. (1998) · Progress in Neurobiology · doi:10.1016/s0301-0082(98)00011-2 · Cited by 882 · see citing works
Carli, M., Robbins, T. W., Evenden, J. L., & Everitt, B. J. (1983) · Behavioural Brain Research · doi:10.1016/0166-4328(83)90138-9 · Cited by 736 · see citing works
Self-citationLocus coeruleus neurons in monkey are selectively activated by attended cues in a vigilance task
Aston-Jones, G., Rajkowski, J., Kubiak, P., & Alexinsky, T. (1994) · The Journal of Neuroscience · doi:10.1523/jneurosci.14-07-04467.1994 · Cited by 637 · see citing works
Hamani, C., Aziz, T. Z., Bloem, B. R., Brown, P., Chabardès, S., Coyne, T. J., Foote, K. D., García‐Rill, E., Hirsch, É. C., Lozano, A. M., et al. (2016) · Stereotactic and Functional Neurosurgery · doi:10.1159/000449010 · Cited by 571 · see citing works
Muir, J. L., Everitt, B. J., & Robbins, T. W. (1996) · Cerebral Cortex · doi:10.1093/cercor/6.3.470 · Cited by 503 · see citing works
Self-citationVoytko, M. L., Olton, D. S., Richardson, R., Gorman, L. K., Tobin, J., & Price, D. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-01-00167.1994 · Cited by 482 · see citing works
McGaughy, J., Kaiser, T., & Sarter, M. (1996) · Behavioral Neuroscience · doi:10.1037/0735-7044.110.2.247 · Cited by 435 · cited 4× · see citing works
“, 1995), divided (Turchi and Sarter, 1997), or sustained (McGaughy et al., 1996) attention in rats.”
BackgroundMethodInfluentialSelf-citationMcGaughy, J. A., Kaiser, T. E., & Sarter, M. F. (1996) · Behavioral Neuroscience · doi:10.1037//0735-7044.110.2.247 · Cited by 435 · see citing works
Self-citationMuir, J. L., Everitt, B. J., & Robbins, T. W. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-04-02313.1994 · Cited by 421 · see citing works
Self-citationThe cerebral cortex of the rat
(1991) · Comparative Biochemistry and Physiology Part A Physiology · doi:10.1016/0300-9629(91)90172-9 · Cited by 416 · see citing works
Locus coeruleus and regulation of behavioral flexibility and attention
(2000) · Progress in Brain Research · doi:10.1016/s0079-6123(00)26013-5 · Cited by 400 · see citing works
McGaughy, J. A., & Sarter, M. F. (1995) · Psychopharmacology · doi:10.1007/bf02246109 · Cited by 348 · see citing works
Self-citationBaxter, M. G., Bucci, D. J., Gorman, L. K., Wiley, R. G., & Gallagher, M. (2013) · Behavioral Neuroscience · doi:10.1037/a0033939 · Cited by 331 · see citing works
Torres, E. M., Perry, T., Blokland, A., Wilkinson, L. S., Wiley, R. G., Lappi, D. A., & Dunnett, S. B. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90010-8 · Cited by 329 · see citing works
Robbins, T. W., Everitt, B. J., Marston, H. M., Wilkinson, J., Jones, G. H., & Page, K. J. (1989) · Behavioural Brain Research · doi:10.1016/s0166-4328(89)80143-3 · Cited by 321 · see citing works
Self-citationDalley, J. W., McGaughy, J., O'Connell, M. T., Cardinal, R. N., Levita, L., & Robbins, T. W. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-13-04908.2001 · Cited by 277 · see citing works
Self-citationEffect sizes and p values: What should be reported and what should be replicated?
Greenwald, A. G., Gonzalez, R., Harris, R., & Guthrie, D. (1996) · Psychophysiology · doi:10.1111/j.1469-8986.1996.tb02121.x · Cited by 273 · see citing works
Bilateral Lesions of the Subthalamic Nucleus Induce Multiple Deficits in an Attentional Task in Rats
Baunez, C., & Robbins, T. W. (1997) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1997.tb01376.x · Cited by 269 · see citing works
Self-citationIncreases in cortical acetylcholine release during sustained attention performance in rats
Himmelheber, A. M., Sarter, M., & Bruno, J. P. (2000) · Cognitive Brain Research · doi:10.1016/s0926-6410(00)00012-4 · Cited by 261 · see citing works
Chiba, A., Bucci, D., Holland, P., & Gallagher, M. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-11-07315.1995 · Cited by 257 · see citing works
Arousal systems and attention.
Robbins, T. W., & Everitt, B. J. (1995) · Cited by 257 · see citing works
Self-citationBaxter, M. G., Bucci, D. J., Gorman, L. K., Wiley, R. G., & Gallagher, M. (1995) · Behavioral Neuroscience · doi:10.1037/0735-7044.109.4.714 · Cited by 248 · see citing works
Gill, T. M., Sarter, M., & Givens, B. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-12-04745.2000 · Cited by 228 · see citing works
Passetti, F., Dalley, J. W., O’Connell, M. T., Everitt, B. J., & Robbins, T. W. (2000) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2000.00183.x · Cited by 223 · see citing works
Self-citationVigilance: Taxonomy And Utility
Parasuraman, R., Warm, J. S., & Dember, W. N. (1987) · Recent research in psychology · doi:10.1007/978-1-4612-4756-2_2 · Cited by 222 · see citing works
Everitt, B. J., Robbins, T. W., & Muir, J. L. (1995) · Psychopharmacology · doi:10.1007/bf02245253 · Cited by 214 · see citing works
Self-citationMetherate, R., & Ashe, J. H. (1993) · Synapse · doi:10.1002/syn.890140206 · Cited by 203 · see citing works
Turchi, J. N., & Sarter, M. F. (1997) · Cognitive Brain Research · doi:10.1016/s0926-6410(97)00027-x · Cited by 165 · see citing works
Metherate, R., & Weinberger, N. M. (1990) · Synapse · doi:10.1002/syn.890060204 · Cited by 164 · see citing works
Cognitive functions of the basal forebrain cholinergic system in monkeys: memory or attention?
Voytko, M. L. (1996) · Behavioural Brain Research · doi:10.1016/0166-4328(95)00143-3 · Cited by 160 · see citing works
The role of basal forebrain neurons in tonic and phasic activation of the cerebral cortex
Détári, L., Rasmusson, D. D., & Semba, K. (1999) · Progress in Neurobiology · doi:10.1016/s0301-0082(98)00084-7 · Cited by 151 · see citing works
192 IgG-saporin : I. Specific Lethality for Cholinergic Neurons in the Basal Forebrain of the Rat
Book, A. A., Wiley, R. G., & Schweitzer, J. B. (1994) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199401000-00012 · Cited by 105 · see citing works
Wrenn, C. C., Lappi, D. A., & Wiley, R. G. (1999) · Brain Research · doi:10.1016/s0006-8993(99)02099-5 · Cited by 94 · see citing works
Skill development in vigilance: Effects of event rate and age.
Parasuraman, R., & Giambra, L. M. (1991) · Psychology and Aging · doi:10.1037//0882-7974.6.2.155 · Cited by 94 · see citing works
Mandel, R. J., Gage, F. H., & Thal, L. J. (1989) · Behavioural Brain Research · doi:10.1016/0166-4328(89)90004-1 · Cited by 91 · see citing works
Skill development in vigilance: Effects of event rate and age.
Parasuraman, R., & Giambra, L. M. (1991) · Psychology and Aging · doi:10.1037/0882-7974.6.2.155 · Cited by 87 · see citing works
Waite, J. J., Wardlow, M. L., & Power, A. E. (1999) · Neurobiology of Learning and Memory · doi:10.1006/nlme.1998.3884 · Cited by 78 · see citing works
Perry, T., Hodges, H. M., & Gray, J. A. (2001) · Brain Research Bulletin · doi:10.1016/s0361-9230(00)00413-5 · Cited by 61 · see citing works
The Effects of Selective Cholinergic Basal Forebrain Lesions and Aging upon Expectancy in the Rat
Stoehr, J. D., Mobley, S. L., Roice, D., et al. (1997) · Neurobiology of Learning and Memory · doi:10.1006/nlme.1997.3768 · Cited by 57 · see citing works
Muir, J. L., Bussey, T. J., Everitt, B. J., & Robbins, T. W. (1996) · Behavioural Brain Research · doi:10.1016/s0166-4328(97)81106-0 · Cited by 50 · see citing works
Self-citationBunsey, M. D., & Strupp, B. J. (1995) · Behavioral Neuroscience · doi:10.1037//0735-7044.109.5.903 · Cited by 48 · see citing works
Tonic and phasic influence of basal forebrain unit activity on the cortical EEG
Détári, L. (2000) · Behavioural Brain Research · doi:10.1016/s0166-4328(00)00256-4 · Cited by 48 · see citing works
Miner, L. A. H., Ostrander, M. M., & Sarter, M. F. (1997) · Journal of Psychopharmacology · doi:10.1177/026988119701100210 · Cited by 47 · see citing works
Lack of effects of lesions of the dorsal noradrenergic bundle on behavioral vigilance.
McGaughy, J. A., Sandstrom, M. I., Ruland, S., et al. (1997) · Behavioral Neuroscience · doi:10.1037/0735-7044.111.3.646 · Cited by 38 · see citing works
Self-citationBunsey, M. D., & Strupp, B. J. (1995) · Behavioral Neuroscience · doi:10.1037/0735-7044.109.5.903 · Cited by 38 · see citing works
Fadel, J. R., Moore, H. M., Sarter, M. F., & Bruno, J. P. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-20-06592.1996 · Cited by 35 · see citing works
Dalley, J. W., Parker, C. A., Wülfert, E., et al. (1998) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0702091 · Cited by 16 · see citing works
Self-citationLack of effects of lesions of the dorsal noradrenergic bundle on behavioral vigilance.
McGaughy, J. A., Sandstrom, M. I., Ruland, S., et al. (1997) · Behavioral Neuroscience · doi:10.1037//0735-7044.111.3.646 · Cited by 3 · see citing works
Self-citation
Flagged first, then by citations
Research works printed but not linked: 1
- Zar JH (1974) Biostatistical analyses. Englewood Cliffs, NJ: Prentice Hall.
Cited by
Sorted by citations
Acetylcholine as a Neuromodulator: Cholinergic Signaling Shapes Nervous System Function and Behavior
Picciotto, M. R., Higley, M. J., & Mineur, Y. S. (2012) · Neuron · doi:10.1016/j.neuron.2012.08.036 · Cited by 1,404 · see citing works
Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates
Dalley, J. W., Cardinal, R. N., & Robbins, T. W. (2004) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2004.09.006 · Cited by 1,329 · see citing works
Self-citationSarter, M., Hasselmo, M. E., Bruno, J. P., & Givens, B. (2005) · Brain Research Reviews · doi:10.1016/j.brainresrev.2004.08.006 · Cited by 667 · see citing works
Prefrontal Acetylcholine Release Controls Cue Detection on Multiple Timescales
Parikh, V., Kozak, R., Martinez, V., & Sarter, M. (2007) · Neuron · doi:10.1016/j.neuron.2007.08.025 · Cited by 623 · see citing works
More attention must be paid: The neurobiology of attentional effort
Sarter, M., Gehring, W. J., & Kozak, R. (2006) · Brain Research Reviews · doi:10.1016/j.brainresrev.2005.11.002 · Cited by 552 · see citing works
Hasselmo, M. E., & McGaughy, J. (2004) · Progress in Brain Research · doi:10.1016/s0079-6123(03)45015-2 · Cited by 525 · see citing works
Self-citationChudasama, Y., & Robbins, T. W. (2006) · Biological Psychology · doi:10.1016/j.biopsycho.2006.01.005 · Cited by 484 · see citing works
Self-citationNeurobehavioral mechanisms of impulsivity: fronto-striatal systems and functional neurochemistry
Dalley, J. W., Mar, A. C., Economidou, D., & Robbins, T. W. (2008) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2007.12.021 · Cited by 467 · see citing works
Acetylcholine contributes through muscarinic receptors to attentional modulation in V1
Herrero, J. L., Roberts, M. J., Delicato, L. S., Gieselmann, M. A., Dayan, P., & Thiele, A. (2008) · Nature · doi:10.1038/nature07141 · Cited by 459 · see citing works
Central Cholinergic Neurons Are Rapidly Recruited by Reinforcement Feedback
Hangya, B., Ranade, S. P., Lorenc, M., & Kepecs, A. (2015) · Cell · doi:10.1016/j.cell.2015.07.057 · Cited by 399 · see citing works
McGaughy, J., Ross, R. S., & Eichenbaum, H. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.01.064 · Cited by 226 · see citing works
Self-citationWinstanley, C. A., Chudasama, Y., Dalley, J. W., Theobald, D. E. H., Glennon, J. C., & Robbins, T. W. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1398-x · Cited by 234 · see citing works
Self-citationNavarra, R., Graf, R., Huang, Y., Logue, S., Comery, T., Hughes, Z., & Day, M. (2008) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2007.06.017 · Cited by 183 · see citing works
Neuromodulation by acetylcholine: examples from schizophrenia and depression
Higley, M. J., & Picciotto, M. R. (2014) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2014.06.004 · Cited by 184 · see citing works
Wilens, T. E., & Decker, M. W. (2007) · Biochemical Pharmacology · doi:10.1016/j.bcp.2007.07.002 · Cited by 164 · see citing works
Augmented Prefrontal Acetylcholine Release during Challenged Attentional Performance
Kozak, R., Bruno, J. P., & Sarter, M. (2006) · Cerebral Cortex · doi:10.1093/cercor/bhi079 · Cited by 144 · see citing works
Newman, L. A., Darling, J., & McGaughy, J. (2008) · Psychopharmacology · doi:10.1007/s00213-008-1097-8 · Cited by 137 · see citing works
Self-citationPrefrontal cortical modulation of acetylcholine release in posterior parietal cortex
Nelson, C. L., Sarter, M., & Bruno, J. P. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2004.12.007 · Cited by 128 · see citing works
Andrzejewski, M. E., Schochet, T. L., Feit, E. C., Harris, R., Mckee, B. L., & Kelley, A. E. (2011) · Behavioral Neuroscience · doi:10.1037/a0022038 · Cited by 96 · see citing works
Nicotinic actions on neuronal networks for cognition: General principles and long-term consequences
Poorthuis, R. B., Goriounova, N. A., Couey, J. J., & Mansvelder, H. D. (2009) · Biochemical Pharmacology · doi:10.1016/j.bcp.2009.04.031 · Cited by 102 · see citing works
Central blockade of muscarinic cholinergic receptors disrupts affective and attentional set‐shifting
Chen, K. C., Baxter, M. G., & Rodefer, J. S. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03548.x · Cited by 97 · see citing works
Obermayer, J., Luchicchi, A., Heistek, T. S., de Kloet, S. F., Terra, H., Bruinsma, B., Mnie-Filali, O., Kortleven, C., Galakhova, A. A., Khalil, A. J., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-13244-9 · Cited by 83 · see citing works
Gau, S. S.-F., & Huang, W.-L. (2014) · Psychological Medicine · doi:10.1017/s0033291713000640 · Cited by 74 · see citing works
The septo-hippocampal system, learning and recovery of function
Niewiadomska, G., Baksalerska-Pazera, M., & Riedel, G. (2009) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2009.03.039 · Cited by 67 · see citing works
Maddux, J.-M., Kerfoot, E. C., Chatterjee, S., & Holland, P. C. (2007) · Behavioral Neuroscience · doi:10.1037/0735-7044.121.1.63 · Cited by 67 · see citing works
Atomoxetine facilitates attentional set shifting in adolescent rats
Cain, R. E., Wasserman, M. C., Waterhouse, B. D., & McGaughy, J. A. (2011) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2011.04.003 · Cited by 55 · see citing works
Self-citationBalducci, C., Nurra, M., Pietropoli, A., Samanin, R., & Carli, M. (2003) · Psychopharmacology · doi:10.1007/s00213-002-1385-7 · Cited by 42 · see citing works
Silveira, M. M., Malcolm, E., Shoaib, M., & Winstanley, C. A. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.12.029 · Cited by 31 · see citing works
McEwen (2004) · doi:10.1016/s1054-3589(04)50016-9 · Cited by 22 · see citing works
Obermayer, J., Luchicchi, A., de Kloet, S. F., Terra, H., Bruinsma, B., Heistek, T. S., Mnie-Filali, O., Kortleven, C., Kroon, T., Jonker, A. J., et al. (2018) · doi:10.1101/461723 · Cited by 83 · see citing works
- Authors
- McGaughy, J., Dalley, J. W., Morrison, C. H., Everitt, B. J., & Robbins, T. W.
- Affiliations
- University of Cambridge (GB)
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 2002-03-01
- Volume
- 22
- Issue
- 5
- Pages
- 1905-1913
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- PMC
- PMC6758873
- OpenAlex
- W1945955617
- Cited by
- 311
- References
- 54
- Citations by year
- 2026: 7 · 2025: 4 · 2024: 9 · 2023: 7 · 2022: 11 · 2021: 6 · 2020: 10 · 2019: 8 · 2018: 13 · 2017: 13 · 2016: 9 · 2015: 11 · 2014: 12 · 2013: 20 · 2012: 9
- FWCI
- 6.62
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Neuroscience (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Wellcome Trust
- Medical Research Council
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- nucleus basalis magnocellularis, 192 IgG-saporin, cholinergic lesions, acetylcholine efflux, visual attention, 5-choice serial reaction time task, choline acetyltransferase, central executive function, basal forebrain, medial frontal cortex
- MeSH terms
- Saporins, Acetylcholine, Animals, Antibodies, Monoclonal, Immunotoxins, Attention, Behavior, Animal, Cell Count, Choice Behavior, Choline O-Acetyltransferase, Drug Administration Routes, Frontal Lobe, Male, Neurons, N-Glycosyl Hydrolases, Rats, Inbred Strains, Reaction Time, Microdialysis, Basal Nucleus of Meynert, Rats, Ribosome Inactivating Proteins, Type 1
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