Cited by 274Escherichia coli research studiesProbiotics and Fermented FoodsBacterial Genetics and Biotechnology

The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.

Surface-layer protein extracts from Lactobacillus helveticus inhibit enterohaemorrhagic Escherichia coli O157:H7 adhesion to epithelial cells

Open access

Johnson-Henry, Kathene C., Hagen, Karen E., Gordonpour, Mahsa, Tompkins, Thomas A., Sherman, Philip M.·2007·Cellular Microbiology

DOI 10.1111/j.1462-5822.2006.00791.x

Open this paper in CoChat — free account Open PDF

Abstract

Adherence of intestinal pathogens, including Escherichia coli O157:H7, to human intestinal epithelial cells is a key step in pathogenesis. Probiotic bacteria, including Lactobacillus helveticus R0052 inhibit the adhesion of E. coli O157:H7 to epithelial cells, a process which may be related to specific components of the bacterial surface. Surface-layer proteins (Slps) are located in a paracrystalline layer outside the bacterial cell wall and are thought to play a role in tissue adherence. However, the ability of S-layer protein extract derived from probiotic bacteria to block adherence of enteric pathogens has not been investigated. Human epithelial (HEp-2 and T84) cells were treated with S-layer protein extract alone, infected with E. coli O157:H7, or pretreated with S-layer protein extract prior to infection to determine their importance in the inhibition of pathogen adherence. The effects of S-layer protein extracts were characterized by phase-contrast and immunofluorescence microscopy and measurement of the transepithelial electrical resistance of polarized monolayers. Pre-treatment of host epithelial cells with S-layer protein extracts prior to E. coli O157:H7 infection decreased pathogen adherence and attaching-effacing lesions in addition to preserving the barrier function of monolayers. These in vitro studies indicate that a non-viable constituent derived from a probiotic strain may prove effective in interrupting the infectious process of an intestinal pathogen.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1111/j.1462-5822.2006.00791.x

Cites

55 of 55 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Pathogenic Escherichia coli
Kaper, J. B., Nataro, J. P., & Mobley, H. L. T. (2004) · Nature Reviews Microbiology · doi:10.1038/nrmicro818 · Cited by 5,583
A gas-liquid solid phase peptide and protein sequenator.
Hewick, R. M., Hunkapiller, M. W., Hood, L., & Dreyer, W. J. (1981) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)43377-7 · Cited by 2,218
Antagonistic activities of lactobacilli and bifidobacteria against microbial pathogens
Servin, A. L. (2004) · FEMS Microbiology Reviews · doi:10.1016/j.femsre.2004.01.003 · Cited by 1,267
The Risk of the Hemolytic–Uremic Syndrome after Antibiotic Treatment ofEscherichia coliO157:H7 Infections
Wong, C. S., Jelačić, S., Habeeb, R. L., Watkins, S. L., & Tarr, P. I. (2000) · New England Journal of Medicine · doi:10.1056/nejm200006293422601 · Cited by 1,084
Potential Uses of Probiotics in Clinical Practice
Reid, G., Jaß, J., Sebulsky, M. T., & McCormick, J. K. (2003) · Clinical Microbiology Reviews · doi:10.1128/cmr.16.4.658-672.2003 · Cited by 918
Adhesion and aggregation ability of probiotic strain Lactobacillus acidophilus M92: ADHESION OF L. ACIDOPHILUS M92
Kos, B., Šušković, J., Vuković, S., Šimpraga, M., Frece, J., & Matošić, S. (2003) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2003.01915.x · Cited by 880
S-layer proteins
Sára, M., & Sleytr, U. B. (2000) · Journal of Bacteriology · doi:10.1128/jb.182.4.859-868.2000 · Cited by 766 · cited 2×
“Given that the S-layer protein forms the outermost layer of gram-positive bacteria (Sára and Sleytr, 2000), it has the potential to play a role in the competitive exclusion of pathogens.”
Background
Lactobacillus species prevents colitis in interleukin 10 gene–deficient mice
Madsen, K. L., Doyle, J. S. G., Jewell, L. D., Tavernini, M. M., & Fedorak, R. N. (1999) · Gastroenterology · doi:10.1016/s0016-5085(99)70013-2 · Cited by 761
Extracellular MUC3 mucin secretion follows adherence of Lactobacillus strains to intestinal epithelial cells in vitro
Mack, D. R., Ahrné, S., Hyde, L., Wei, S. H., & Hollingsworth, M. A. (2003) · Gut · doi:10.1136/gut.52.6.827 · Cited by 686
Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation
Berkes, J., Viswanathan, V. K., Savkovic, S. D., & Hecht, G. (2003) · Gut · doi:10.1136/gut.52.3.439 · Cited by 594

Show all 55 references

Research works printed but not linked: 1

Johnson-Henry K.C., 2005, Nutrafoods, 23, 29

Sorted by citations

Bacterial competition: surviving and thriving in the microbial jungle
Hibbing, M. E., Fuqua, C., Parsek, M. R., & Peterson, S. B. (2009) · Nature Reviews Microbiology · doi:10.1038/nrmicro2259 · Cited by 2,765
Genes and Molecules of Lactobacilli Supporting Probiotic Action
Lebeer, S., Vanderleyden, J., & De Keersmaecker, S. C. J. (2008) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00017-08 · Cited by 1,013
Probiotics and the gut microbiota in intestinal health and disease
Gareau, M. G., Sherman, P. M., & Walker, W. A. (2010) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2010.117 · Cited by 907
Self-citation
Probiotic bacteria and intestinal epithelial barrier function
Ohland, C., & MacNaughton, W. K. (2010) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00243.2009 · Cited by 832
Postbiotics-Parabiotics: The New Horizons in Microbial Biotherapy and Functional Foods
Nataraj, B. H., Ali, S. A., Behare, P. V., & Yadav, H. (2020) · Microbial Cell Factories · doi:10.1186/s12934-020-01426-w · Cited by 737
Emerging molecular insights into the interaction between probiotics and the host intestinal mucosa
Bron, P. A., van Baarlen, P., & Kleerebezem, M. (2012) · Nature Reviews Microbiology · doi:10.1038/nrmicro2690 · Cited by 690
Health Benefits of Heat-Killed (Tyndallized) Probiotics: An Overview
Piqué, N., Berlanga, M., & Miñana-Galbis, D. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20102534 · Cited by 642
Surface components and metabolites of probiotics for regulation of intestinal epithelial barrier
Liu, Q., Yu, Z., Tian, F., Zhao, J., Zhang, H., Zhai, Q., & Chen, W. (2020) · Microbial Cell Factories · doi:10.1186/s12934-020-1289-4 · Cited by 456
Paraprobiotics and Postbiotics of Probiotic Lactobacilli, Their Positive Effects on the Host and Action Mechanisms: A Review
Teame, T., Wang, A., Xie, M., Zhang, Z., Yang, Y., Ding, Q., Gao, C., Olsen, R. E., Ran, C., & Zhou, Z. (2020) · Frontiers in Nutrition · doi:10.3389/fnut.2020.570344 · Cited by 428
The extracellular biology of the lactobacilli
Kleerebezem, M., Pascal Hols, A., Bernard, E., Rolain, T., Zhou, M., Siezen, R. J., & Bron, P. A. (2009) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2009.00208.x · Cited by 399
Trends in dairy and non-dairy probiotic products - a review
Kumar, B. V., Vijayendra, S. V. N., & Reddy, O. V. S. (2015) · Journal of Food Science and Technology · doi:10.1007/s13197-015-1795-2 · Cited by 380
Molecular insights into probiotic mechanisms of action employed against intestinal pathogenic bacteria
van Zyl, W. F., Deane, S. M., & Dicks, L. M. T. (2020) · Gut Microbes · doi:10.1080/19490976.2020.1831339 · Cited by 357
Molecular dialogue between the human gut microbiota and the host: a Lactobacillus and Bifidobacterium perspective
Turroni, F., Ventura, M., Buttó, L. F., Duranti, S., O’Toole, P. W., Motherway, M. O., & van Sinderen, D. (2014) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1318-0 · Cited by 336
Lactobacillus surface layer proteins: Structure, function and applications
Hynönen, U., & Palva, A. (2013) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-013-4962-2 · Cited by 283
Structural elucidation and antioxidant activities of exopolysaccharides from Lactobacillus helveticus MB2-1
Li, W., Ji, J., Chen, X., Jiang, M., Rui, X., & Dong, M. (2013) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2013.11.053 · Cited by 271
Antimicrobial Activity – The Most Important Property of Probiotic and Starter Lactic Acid Bacteria
Šušković, J., Kos, B., Beganović, J., Pavunc, A. L., Habjanič, K., & Matošić, S. (2010) · University of Zagreb University Computing Centre (SRCE) · Cited by 268
Probiotics and chronic kidney disease
Koppe, L., Mafra, D., & Fouque, D. P. (2015) · Kidney International · doi:10.1038/ki.2015.255 · Cited by 266
Lactobacillus rhamnosus Strain GG Prevents Enterohemorrhagic Escherichia coli O157:H7-Induced Changes in Epithelial Barrier Function
Johnson‐Henry, K., Donato, K. A., Shen-Tu, G., Gordanpour, M., & Sherman, P. M. (2008) · Infection and Immunity · doi:10.1128/iai.00778-07 · Cited by 289
Self-citation
Lactobacillus helveticus: the proteolytic system
Griffiths, M. W., & Tellez, A. M. (2013) · Frontiers in Microbiology · doi:10.3389/fmicb.2013.00030 · Cited by 241
“Another study conducted on the effect of L. helveticus R0052 to inhibit E coli O157:H7 attachment (Johnson-Henry et al., 2007), tested the influence of different media on the S-layer protein.”
BackgroundInfluential
Vitamin D Deficiency Promotes Epithelial Barrier Dysfunction and Intestinal Inflammation
Assa, A., Vong, L., Pinnell, L. J., Avitzur, N., Johnson‐Henry, K. C., & Sherman, P. M. (2014) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiu235 · Cited by 239
Self-citation
Predominant gut Lactobacillus murinus strain mediates anti-inflammaging effects in calorie-restricted mice
Pan, F., Zhang, L., Li, M., Hu, Y., Zeng, B., Yuan, H., Zhao, L., & Zhang, C. (2018) · Microbiome · doi:10.1186/s40168-018-0440-5 · Cited by 241
Unraveling Mechanisms of Action of Probiotics
Sherman, P. M., Ossa, J. C., & Johnson‐Henry, K. (2009) · Nutrition in Clinical Practice · doi:10.1177/0884533608329231 · Cited by 230
Self-citation
Mechanisms of probiosis and prebiosis: considerations for enhanced functional foods
Saulnier, D. M. A., Spinler, J. K., Gibson, G. R., & Versalovic, J. A. (2009) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2009.01.002 · Cited by 236
Lactobacillus rhamnosus GG attenuates interferon-γ and tumour necrosis factor-α-induced barrier dysfunction and pro-inflammatory signalling
Donato, K. A., Gareau, M. G., Wang, Y. J. J., & Sherman, P. M. (2010) · Microbiology · doi:10.1099/mic.0.040139-0 · Cited by 212
Self-citation
Antimicrobial Resistance and Recent Alternatives to Antibiotics for the Control of Bacterial Pathogens with an Emphasis on Foodborne Pathogens
Helmy, Y. A., Taha-Abdelaziz, K., Hawwas, H. A. E.-H., Ghosh, S. B., Alkafaas, S. S., Moawad, M. M. M., Saied, E. M., Kassem, I. I., & Mawad, A. M. M. (2023) · Antibiotics · doi:10.3390/antibiotics12020274 · Cited by 253
Probiotics as potential alternative biocontrol agents in the agriculture and food industries: A review
Hossain, M. I., Sadekuzzaman, M., & Ha, S. (2017) · Food Research International · doi:10.1016/j.foodres.2017.07.077 · Cited by 210
Adherence factors ofLactobacillusin the human gastrointestinal tract
Vélez, M. P., Keersmaecker, S. C. J. D., & Vanderleyden, J. (2007) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2007.00908.x · Cited by 207
Combination of Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 reduces post-myocardial infarction depression symptoms and restores intestinal permeability in a rat model
Arseneault-Bréard, J., Rondeau, I., Gilbert, K., Girard, S.-A., Tompkins, T. A., Godbout, R., & Rousseau, G. (2012) · British Journal of Nutrition · doi:10.1017/s0007114511005137 · Cited by 205
Self-citation
Influence of functional food components on gut health
Wan, M. L. Y., Ling, K. H., El-Nezami, H. S., & Wang, M. (2018) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2018.1433629 · Cited by 213
Probiotics and competitive exclusion of pathogens in shrimp aquaculture
Knipe, H., Temperton, B., Lange, A., Bass, D., & Tyler, C. R. (2020) · Reviews in Aquaculture · doi:10.1111/raq.12477 · Cited by 208
The Bacillus cereus Food Infection as Multifactorial Process
Jeßberger, N., Dietrich, R., Granum, P. E., & Märtlbauer, E. P. (2020) · Toxins · doi:10.3390/toxins12110701 · Cited by 199
Shigella Diversity and Changing Landscape: Insights for the Twenty-First Century
Anderson, M. C., Sansonetti, P. J., & Marteyn, B. (2016) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2016.00045 · Cited by 184
Probiotics interaction with foodborne pathogens: a potential alternative to antibiotics and future challenges
Wan, M. L. Y., Forsythe, S. J., & El-Nezami, H. S. (2018) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2018.1490885 · Cited by 185
Health-Promoting Properties of Lactobacillus helveticus
Taverniti, V., & Guglielmetti, S. (2012) · Frontiers in Microbiology · doi:10.3389/fmicb.2012.00392 · Cited by 156
Exported proteins in probiotic bacteria: adhesion to intestinal surfaces, host immunomodulation and molecular cross-talking with the host
Sánchez, B., Bressollier, P., & Urdaci, M. C. (2008) · FEMS Immunology & Medical Microbiology · doi:10.1111/j.1574-695x.2008.00454.x · Cited by 141
Bifidobacterium longum and Lactobacillus helveticus Synergistically Suppress Stress-related Visceral Hypersensitivity Through Hypothalamic-Pituitary-Adrenal Axis Modulation
Ait-Belgnaoui, A., Payard, I., Rolland, C., Harkat, C., Braniste, V., Théodorou, V., & Tompkins, T. A. (2018) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm16167 · Cited by 140
Self-citation
Normal and tumour cervical cells respond differently to vaginal lactobacilli, independent of pH and lactate
Motevaseli, E., Shirzad, ‪., Akrami, S. M., Mousavi, A., Mirsalehian, A., & Modarressi, M. H. (2013) · Journal of Medical Microbiology · doi:10.1099/jmm.0.057521-0 · Cited by 134
S-Layer Protein Mediates the Stimulatory Effect of Lactobacillus helveticus MIMLh5 on Innate Immunity
Taverniti, V., Stuknytė, M., Minuzzo, M., Arioli, S., Noni, I. D., Scabiosi, C., Córdova, Z. M., Junttila, I., Hämäläinen, S., Turpeinen, H., et al. (2012) · Applied and Environmental Microbiology · doi:10.1128/aem.03056-12 · Cited by 120
Effect of growth time on the surface and adhesion properties of Lactobacillus rhamnosus GG
Deepika, G., Green, R., Frazier, R. A., & Charalampopoulos, D. (2009) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2009.04306.x · Cited by 117
Strain-specific probiotic (Lactobacillus helveticus) inhibition ofCampylobacter jejuni invasion of human intestinal epithelial cells
Wine, E., Gareau, M. G., Johnson‐Henry, K. C., & Sherman, P. M. (2009) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2009.01781.x · Cited by 113
Self-citation
The biological activities of postbiotics in gastrointestinal disorders
Abbasi, A., Rad, A. H., Ghasempour, Z., Sabahi, S., Kafil, H. S., Hasannezhad, P., Saadat, Y. R., & Shahbazi, N. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1895061 · Cited by 114
The Complex Role of Lactic Acid Bacteria in Food Detoxification
Petrova, P. M., Arsov, A., Tsvetanova, F. V., Parvanova-Mancheva, T., Vasileva, E., Tsigoriyna, L., & Petrov, K. K. (2022) · Nutrients · doi:10.3390/nu14102038 · Cited by 117
Zoonotic helminth infections of humans: echinococcosis, cysticercosis and fascioliasis
Garcia, H. H., Moro, P. L., & Schantz, P. M. (2007) · Current Opinion in Infectious Diseases · doi:10.1097/qco.0b013e3282a95e39 · Cited by 106
How can probiotics and prebiotics impact mucosal immunity?
O'Flaherty, S., Saulnier, D., Pot, B., & Versalovic, J. (2010) · Gut Microbes · doi:10.4161/gmic.1.5.12924 · Cited by 103
Chapter 2 Adherence, Anti‐Adherence, and Oligosaccharides
Shoaf‐Sweeney, K. D., & Hutkins, R. W. (2008) · Advances in food and nutrition research · doi:10.1016/s1043-4526(08)00402-6 · Cited by 104
Probiotic and anti-inflammatory attributes of an isolate Lactobacillus helveticus NS8 from Mongolian fermented koumiss
Rong, J., Zheng, H., Liu, M., Hu, X., Wang, T., Zhang, X., Jin, F., & Wang, L. (2015) · BMC Microbiology · doi:10.1186/s12866-015-0525-2 · Cited by 99
In vitro assessment of Pediococcus acidilactici Kp10 for its potential use in the food industry
Abbasiliasi, S., Tan, J. S., Bashokouh, F., Ibrahim, T. A. T., Mustafa, S., Vakhshiteh, F., Sivasamboo, S., & Ariff, A. (2017) · BMC Microbiology · doi:10.1186/s12866-017-1000-z · Cited by 109
Proteins of novel lactic acid bacteria from Apis mellifera mellifera: an insight into the production of known extra-cellular proteins during microbial stress
Butler, E. I., Alsterfjord, M., Olofsson, T. C., Karlsson, C. A. Q., Malmström, J. A., & Vásquez, A. (2013) · BMC Microbiology · doi:10.1186/1471-2180-13-235 · Cited by 99
Antagonistic Activity of Lactobacillus reuteri Strains on the Adhesion Characteristics of Selected Pathogens
Singh, T. P., Kaur, G., Kapila, S., & Malik, R. K. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.00486 · Cited by 103
Lactobacillus jensenii Surface-Associated Proteins Inhibit Neisseria gonorrhoeae Adherence to Epithelial Cells
Spurbeck, R. R., & Arvidson, C. G. (2010) · Infection and Immunity · doi:10.1128/iai.01200-09 · Cited by 90
Characterization of the gut microbiota of migratory passerines during stopover along the northern coast of the Gulf of Mexico
Lewis, W. B., Moore, F. R., & Wang, S. (2016) · Journal of Avian Biology · doi:10.1111/jav.00954 · Cited by 88
Vitamin D Deficiency Predisposes to Adherent-invasive Escherichia coli-induced Barrier Dysfunction and Experimental Colonic Injury
Assa, A., Vong, L., Pinnell, L. J., Rautava, J., Avitzur, N., Johnson‐Henry, K. C., & Sherman, P. M. (2015) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000282 · Cited by 85
Self-citation
Lactobacilli antagonize biological effects of enterohaemorrhagic Escherichia coli in vitro
Hugo, A. A., Kakisu, E. J., Antoni, G. L. D., & Pérez, P. F. (2008) · Letters in Applied Microbiology · doi:10.1111/j.1472-765x.2008.02363.x · Cited by 84
Flow cytometry: a versatile technology for specific quantification and viability assessment of micro-organisms in multistrain probiotic products
Chiron, C., Tompkins, T. A., & Burguière, P. (2017) · Journal of Applied Microbiology · doi:10.1111/jam.13666 · Cited by 85
Self-citation
Role of surface layer collagen binding protein from indigenous Lactobacillus plantarum 91 in adhesion and its anti-adhesion potential against gut pathogen
Yadav, A. K., Tyagi, A., Kaushik, J. K., Saklani, A. C., Grover, S., & Batish, V. K. (2013) · Microbiological Research · doi:10.1016/j.micres.2013.05.003 · Cited by 83
Functionality of the S-layer protein from the probiotic strain Lactobacillus helveticus M92
Beganović, J., Frece, J., Kos, B., Pavunc, A. L., Habjanič, K., & Šušković, J. (2011) · Antonie van Leeuwenhoek · doi:10.1007/s10482-011-9563-4 · Cited by 83
Isolation of surface (S) layer protein carrying Lactobacillus species from porcine intestine and faeces and characterization of their adhesion properties to different host tissues
Jakava-Viljanen, M., & Palva, A. (2007) · Veterinary Microbiology · doi:10.1016/j.vetmic.2007.04.029 · Cited by 82
Probiotics: Mechanisms of Action and Clinical Applications
Gogineni, V. K., & Morrow, L. E. (2013) · Journal of Probiotics & Health · doi:10.4172/2329-8901.1000101 · Cited by 82
Escherichia coli Shiga Toxins and Gut Microbiota Interactions
Lee, K., Jeong, Y., & Lee, M. (2021) · Toxins · doi:10.3390/toxins13060416 · Cited by 82
Immunomodulation Potential of Probiotics: A Novel Strategy for Improving Livestock Health, Immunity, and Productivity
Kober, A. K. M. H., Rajoka, M. S. R., Mehwish, H. M., Villena, J., & Kitazawa, H. (2022) · Microorganisms · doi:10.3390/microorganisms10020388 · Cited by 88
The microbiome and host mucosal interactions in urinary tract diseases
Jones, B., Chonwerawong, M., Marcelino, V. R., Deshpande, A., Forster, S. C., & Starkey, M. R. (2021) · Mucosal Immunology · doi:10.1038/s41385-020-00372-5 · Cited by 82
Genomic Comparison of Lactobacillus helveticus Strains Highlights Probiotic Potential
Fontana, A., Falasconi, I., Molinari, P., Treu, L., Basile, A., Vezzi, A., Campanaro, S., & Morelli, L. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.01380 · Cited by 81
Controlling foodborne pathogens with natural antimicrobials by biological control and antivirulence strategies
Abdelhamid, A. G., & Dougdoug, N. K. E. (2020) · Heliyon · doi:10.1016/j.heliyon.2020.e05020 · Cited by 77
Lactobacilli at the Front Line of Defense Against Vaginally Acquired Infections
Spurbeck, R. R., & Arvidson, C. G. (2011) · Future Microbiology · doi:10.2217/fmb.11.36 · Cited by 78
A comprehensive post-market review of studies on a probiotic product containing Lactobacillus helveticus R0052 and Lactobacillus rhamnosus R0011
Foster, L., Tompkins, T. A., & Dahl, W. J. (2011) · Beneficial Microbes · doi:10.3920/bm2011.0032 · Cited by 77
Self-citation
Adhesive ability means inhibition activities for lactobacillus against pathogens and S-layer protein plays an important role in adhesion
Zhang, W., Wang, H., Liu, J., Zhao, Y., Gao, K., & Zhang, J. (2013) · Anaerobe · doi:10.1016/j.anaerobe.2013.06.005 · Cited by 75
Lactobacillus rhamnosus GR-1 Ameliorates Escherichia coli-Induced Inflammation and Cell Damage via Attenuation of ASC-Independent NLRP3 Inflammasome Activation
Wu, Q., Liu, M., Yang, J., Wang, J., & Zhu, Y. (2015) · Applied and Environmental Microbiology · doi:10.1128/aem.03044-15 · Cited by 75
Lactobacillus Fermentum Isolated from Human Colonic Mucosal Biopsy Inhibits the Growth and Adhesion of Enteric and Foodborne Pathogens
Varma, P., Dinesh, K. R., Menon, K. N., & Biswas, R. (2010) · Journal of Food Science · doi:10.1111/j.1750-3841.2010.01818.x · Cited by 74
Surface proteins from Lactobacillus kefir antagonize in vitro cytotoxic effect of Clostridium difficile toxins
Carasi, P., Trejo, F. M., Pérez, P. F., Antoni, G. L. D., & Serradell, M. D. L. Á. (2011) · Anaerobe · doi:10.1016/j.anaerobe.2011.11.002 · Cited by 75
Lactobacillus salivarius alleviates inflammation via NF-κB signaling in ETEC K88-induced IPEC-J2 cells
Qiao, J., Sun, Z., Liang, D., & Li, H. (2020) · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · doi:10.1186/s40104-020-00488-5 · Cited by 73
Extractable Bacterial Surface Proteins in Probiotic–Host Interaction
Carmo, F. L. R. D., Rabah, H., Carvalho, R. D. D. O., Gaucher, F., Cordeiro, B. F., da Silva, S. H., Loir, Y. L., Azevedo, V., & Jan, G. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.00645 · Cited by 72
Synergistic efficacy of pulsed magnetic fields and Litseacubeba essential oil treatment against Escherichia coli O157:H7 in vegetable juices
Lin, L., Wang, X., & Cui, H. (2019) · Food Control · doi:10.1016/j.foodcont.2019.06.012 · Cited by 68
Modern Approaches in Probiotics Research to Control Foodborne Pathogens
Amalaradjou, M. A. R., & Bhunia, A. K. (2012) · Advances in food and nutrition research · doi:10.1016/b978-0-12-394598-3.00005-8 · Cited by 72
Inhibition of Staphylococcus aureus adherence to Caco-2 cells by lactobacilli and cell surface properties that influence attachment
Ren, D., Li, C., Qin, Y., Yin, R., Li, X., Tian, M., Du, S., Guo, H., Liu, C., Zhu, N., et al. (2012) · Anaerobe · doi:10.1016/j.anaerobe.2012.08.001 · Cited by 68
Lactobacillus fermentum ATCC 23271 Displays In vitro Inhibitory Activities against Candida spp.
do Carmo, M. S., Noronha, F. M. F., Arruda, M. O., Costa, E. P. D. S., Bomfim, M. R. Q., Monteiro, A. S., Ferro, T. A. F., Fernandes, E. S., Girón, J. A., & Monteiro‐Neto, V. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.01722 · Cited by 69
Postbiotic effects of Lactobacillus fermentate on intestinal health, mucosa-associated microbiota, and growth efficiency of nursery pigs challenged with F18+Escherichia coli
Xu, X., Duarte, M. E., & Kim, S. W. (2022) · Journal of Animal Science · doi:10.1093/jas/skac210 · Cited by 72
Inhibition of Shigella sonnei adherence to HT-29 cells by lactobacilli from Chinese fermented food and preliminary characterization of S-layer protein involvement
Zhang, Y., Zhang, L., Tuo, Y., Guo, C., Yi, H., Li, J., Han, X., & Du, M. (2010) · Research in Microbiology · doi:10.1016/j.resmic.2010.06.005 · Cited by 66
Enhancement of Epithelial Barrier Function by Probiotics
Madsen, K. L. (2012) · Journal of Epithelial Biology & Pharmacology · doi:10.2174/1875044301205010055 · Cited by 68
Conserved S-Layer-Associated Proteins Revealed by Exoproteomic Survey of S-Layer-Forming Lactobacilli
Johnson, B. R., Hymes, J. P., Sanozky-Dawes, R., Henriksen, E. D., Barrangou, R., & Klaenhammer, T. R. (2015) · Applied and Environmental Microbiology · doi:10.1128/aem.01968-15 · Cited by 66
Heterogeneity of S-layer proteins from aggregating and non-aggregating Lactobacillus kefir strains
Mobili, P., Serradell, M. D. L. Á., Trejo, S. A., Avilés, F. X., Abraham, A. G., & Antoni, G. L. D. (2009) · Antonie van Leeuwenhoek · doi:10.1007/s10482-009-9322-y · Cited by 64
Adhesion ofLactobacilliand their anti-infectivity potential
Yadav, A. K., Tyagi, A., Kumar, A., Panwar, S., Grover, S., Saklani, A. C., Rajkumar, H., & Batish, V. K. (2015) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2014.918533 · Cited by 68
Measuring Kinetic Dissociation/Association Constants Between Lactococcus lactis Bacteria and Mucins Using Living Cell Probes
Le, D. T. L., Guérardel, Y., Loubière, P., Mercier‐Bonin, M., & Dague, É. (2011) · Biophysical Journal · doi:10.1016/j.bpj.2011.10.034 · Cited by 64
Antagonistic effects of Lactobacillus plantarum 0612 on the adhesion of selected foodborne enteropathogens in various colonic environments
Lau, L. Y. J., & Chye, F. Y. (2018) · Food Control · doi:10.1016/j.foodcont.2018.04.001 · Cited by 68
Influence of microbial probiotics on ruminant health and nutrition: sources, mode of action and implications
Reuben, R. C., Elghandour, M. M. M. Y., Alqaisi, O., Cone, J. W., Molina, O. M., & Salem, A. Z. M. (2021) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.11643 · Cited by 71
S-layer proteins of Lactobacillus acidophilus inhibits JUNV infection
Martínez, M. G., Acosta, M., Candurra, N. A., & Ruzal, S. M. (2012) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2012.05.031 · Cited by 61
Lactobacilli Reduce Chemokine IL-8 Production in Response to TNF-αandSalmonellaChallenge of Caco-2 Cells
Ren, D., Li, C., Qin, Y.-Q., Yin, R., Du, S., Ye, F., Liu, H.-F., Wang, M., Sun, Y., Li, X., et al. (2013) · BioMed Research International · doi:10.1155/2013/925219 · Cited by 61
In vitro assessment of the antimicrobial potentials of Lactobacillus helveticus strains isolated from traditional cheese in Sinkiang China against food-borne pathogens
Bian, X., Evivie, S. E., Muhammad, Z., Luo, G., Liang, H.-Z., Wang, N., & Huo, G. (2015) · Food & Function · doi:10.1039/c5fo01041a · Cited by 61
Using lactic acid bacteria as an immunostimulants in cultured shrimp with special reference to Lactobacillus spp.
Naiel, M. A. E., Farag, M. R., Gewida, A. G. A., Elnakeeb, M. A., Amer, M. S., & Alagawany, M. M. (2020) · Aquaculture International · doi:10.1007/s10499-020-00620-2 · Cited by 59
Probiotics Prevent Death Caused byCitrobacter rodentiumInfection in Neonatal Mice
Gareau, M. G., Wine, E., Reardon, C., & Sherman, P. M. (2009) · The Journal of Infectious Diseases · doi:10.1086/648614 · Cited by 59
Self-citation
Lactobacillus plantarum surface layer adhesive protein protects intestinal epithelial cells against tight junction injury induced by enteropathogenic Escherichia coli
Liu, Z., Shen, T., Zhang, P., Ma, Y., & Qin, H. (2010) · Molecular Biology Reports · doi:10.1007/s11033-010-0457-8 · Cited by 58
Probiotics and Gastrointestinal Infections
Britton, R. A., & Versalovic, J. A. (2008) · Interdisciplinary Perspectives on Infectious Diseases · doi:10.1155/2008/290769 · Cited by 57
Safety evaluation of two bacterial strains used in asian probiotic products
Tompkins, T. A., Hagen, K. E., Wallace, T. D., & Fillion-Forté, V. (2008) · Canadian Journal of Microbiology · doi:10.1139/w08-022 · Cited by 55
Self-citation
Fish Probiotics: Cell Surface Properties of Fish Intestinal Lactobacilli and Escherichia coli
Mirzabekyan, S., Harutyunyan, N., Manvelyan, A., Malkhasyan, L., Balayan, M. H., Miralimova, S. M., Chikindas, M. L., Chistyakov, V. A., & Pepoyan, A. (2023) · Microorganisms · doi:10.3390/microorganisms11030595 · Cited by 54
Understanding the adhesion mechanism of a mucin binding domain from Lactobacillus fermentum and its role in enteropathogen exclusion
Chatterjee, M., Pushkaran, A. C., Vasudevan, A. K., Menon, K. N., Biswas, R., & Mohan, C. G. (2017) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2017.10.107 · Cited by 54
Modulation of Enterohaemorrhagic Escherichia coli Survival and Virulence in the Human Gastrointestinal Tract
Jubelin, G., Desvaux, M., Schüller, S., Etienne‐Mesmin, L., Muniesa, M., & Blanquet‐Diot, S. (2018) · Microorganisms · doi:10.3390/microorganisms6040115 · Cited by 55
Updates on the Role of Probiotics against Different Health Issues: Focus on Lactobacillus
Un-Nisa, A., Khan, A., Zakria, M., Siraj, S., Ullah, S., Tipu, M. K., Ikram, M. A., & Kim, M. O. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms24010142 · Cited by 64
Characterization of surface layer proteins and its role in probiotic properties of three Lactobacillus strains
Meng, J., Zhu, X. D., Gao, S., Zhang, Q., Sun, Z., & Lu, R. (2014) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2014.01.024 · Cited by 54
The Role of Probiotics, Prebiotics, Synbiotics, and Postbiotics in Livestock and Poultry Gut Health: A Review
Yue, T., Yanan, L., Ding, W., Xu, B., Zhang, C., Li, L., Jian, F., & Huang, S. (2025) · Metabolites · doi:10.3390/metabo15070478 · Cited by 59
Occurrence, Structure, Chemistry, Genetics, Morphogenesis, and Functions of S-Layers
Messner, P., Schäffer, C., Egelseer, E. M., & Sleytr, U. B. (2010) · Springer eBooks · doi:10.1007/978-3-642-05062-6_2 · Cited by 49
Systems biology of robustness and flexibility: Lactobacillus buchneri —A show case
Heinl, S., & Grabherr, R. M. (2017) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2017.01.007 · Cited by 49

Authors: Johnson-Henry, K. C., Hagen, K. E., Gordonpour, M., Tompkins, T. A., & Sherman, P. M.
Affiliations: Lallemand (Canada) (CA)
University of Toronto (CA)
Corresponding author: Sherman, Philip M.
ORCID: Tompkins, Thomas A.
Sherman, Philip M.
Venue: Cellular Microbiology
Publisher: Hindawi Limited
Published: 2007-02
Volume: 9
Issue: 2
Pages: 356-367
ISSN: 1462-5814 (ISSN-L)
1462-5822
DOI: 10.1111/j.1462-5822.2006.00791.x
OpenAlex: W2151081251
Cited by: 274
References: 55
Citations by year: 2026: 4 · 2025: 11 · 2024: 4 · 2023: 15 · 2022: 19 · 2021: 11 · 2020: 19 · 2019: 14 · 2018: 15 · 2017: 14 · 2016: 15 · 2015: 17 · 2014: 10 · 2013: 17 · 2012: 25
FWCI: 5.94
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: doi.wiley.com/10.1002/tdm_license_1.1 (tdm, 3134 d)
Locations: Cellular Microbiology (publishedVersion)
PubMed (publishedVersion)
Funders: University of Guelph
Canada Research Chairs
University of Toronto
Hospital for Sick Children
Canadian Institutes of Health Research
Topics: Life Sciences › Immunology and Microbiology › Microbiology › Escherichia coli research studies
Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
Keywords: Lactobacillus helveticus, Escherichia coli O157:H7, surface layer protein, probiotics, bacterial adhesion inhibition, intestinal epithelial cells, attaching and effacing lesions, epithelial barrier function, transepithelial electrical resistance
MeSH terms: Bacterial Adhesion, Bacterial Outer Membrane Proteins, Bacterial Proteins, Cell Line, Epithelial Cells, Escherichia coli O157, Lactobacillus helveticus

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Surface-layer protein extracts from Lactobacillus helveticus inhibit enterohaemorrhagic Escherichia coli O157:H7 adhesion to epithelial cells

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks