Postbiotics-Parabiotics: The New Horizons in Microbial Biotherapy and Functional Foods

Nataraj, Basavaprabhu H.; Ali, Syed Azmal; Behare, Pradip V.; Yadav, Hariom

doi:10.1186/s12934-020-01426-w

Cited by 737Probiotics and Fermented FoodsProtein Hydrolysis and Bioactive PeptidesGut microbiota and health

Postbiotics-Parabiotics: The New Horizons in Microbial Biotherapy and Functional Foods

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Nataraj, Basavaprabhu H., Ali, Syed Azmal, Behare, Pradip V., Yadav, Hariom·2020·Microbial Cell Factories

DOI 10.1186/s12934-020-01426-wPMC PMC7441679

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Abstract

Probiotics have several health benefits by modulating gut microbiome; however, techno-functional limitations such as viability controls have hampered their full potential applications in the food and pharmaceutical sectors. Therefore, the focus is gradually shifting from viable probiotic bacteria towards non-viable paraprobiotics and/or probiotics derived biomolecules, so-called postbiotics. Paraprobiotics and postbiotics are the emerging concepts in the functional foods field because they impart an array of health-promoting properties. Although, these terms are not well defined, however, for time being these terms have been defined as here. The postbiotics are the complex mixture of metabolic products secreted by probiotics in cell-free supernatants such as enzymes, secreted proteins, short chain fatty acids, vitamins, secreted biosurfactants, amino acids, peptides, organic acids, etc. While, the paraprobiotics are the inactivated microbial cells of probiotics (intact or ruptured containing cell components such as peptidoglycans, teichoic acids, surface proteins, etc.) or crude cell extracts (i.e. with complex chemical composition)". However, in many instances postbiotics have been used for whole category of postbiotics and parabiotics. These elicit several advantages over probiotics like; (i) availability in their pure form, (ii) ease in production and storage, (iii) availability of production process for industrial-scale-up, (iv) specific mechanism of action, (v) better accessibility of Microbes Associated Molecular Pattern (MAMP) during recognition and interaction with Pattern Recognition Receptors (PRR) and (vi) more likely to trigger only the targeted responses by specific ligand-receptor interactions. The current review comprehensively summarizes and discussed various methodologies implied to extract, purify, and identification of paraprobiotic and postbiotic compounds and their potential health benefits.

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Some EPSs identified from LAB have biological functions including free radical scavenging, free cholesterol binding, gut microbiota modulation, antitumor, antimicrobial, and antibiofilm properties.
“Several LAB species, particularly those of the genus Lactobacillus, are capable of producing EPSs, and some of the EPSs identified to date by LAB have been shown to have biological functions, such as free radical scavenging, free cholesterol binding, gut microbiota modulation, antitumor, antimicrobial, and antibiofilm properties [8,15,16].”
From Analysis of Chemical Structure and Antibiofilm Properties of Exopolysaccharides from Lactiplantibacillus plantarum EIR/IF-1 Postbiotics (2022) · cites this paper as [8]
The Exopolysaccharides section (page unavailable) says LAB produce EPS and reports free-radical scavenging, free-cholesterol binding, gut microbiota modulation, antitumor, and antibiofilm effects, with antitumor effects described in preclinical trials. It does not identify a separate antimicrobial effect of EPS; the table in the Biosurfactants section attributes antimicrobial effects to biosurfactants instead. (LLM, conf=0.88)
Experimental — accuracy not yet measured
Several LAB species, particularly those of the genus Lactobacillus, are capable of producing EPSs.
“Several LAB species, particularly those of the genus Lactobacillus, are capable of producing EPSs, and some of the EPSs identified to date by LAB have been shown to have biological functions”
From Analysis of Chemical Structure and Antibiofilm Properties of Exopolysaccharides from Lactiplantibacillus plantarum EIR/IF-1 Postbiotics (2022) · cites this paper as [8]

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Untitled work
Hill (2014) · doi:10.1038/nrgastro.2014.66 · Cited by 9,592 · see citing works
Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics
Gibson, G. R., Hutkins, R., Sanders, M. E., Prescott, S. L., Reimer, R. A., Salminen, S. J., Scott, K., Stanton, C., Swanson, K. S., Cani, P. D., et al. (2017) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2017.75 · Cited by 5,634 · see citing works
Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases
Parada Venegas, D., De la Fuente, M. K., Landskron, G., González, M. J., Quera, R., Dijkstra, G., Harmsen, H. J. M., Faber, K. N., & Hermoso, M. A. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00277 · Cited by 3,820 · see citing works
Peptidoglycan structure and architecture
Vollmer, W., Blanot, D., & de Pedro, M. A. (2008) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2007.00094.x · Cited by 2,355 · see citing works
Global burden of disease in young people aged 10–24 years: a systematic analysis
Gore, F. M., Bloem, P. J., Patton, G. C., Ferguson, J., Joseph, V., Coffey, C., Sawyer, S. M., & Mathers, C. D. (2011) · The Lancet · doi:10.1016/s0140-6736(11)60512-6 · Cited by 2,301 · see citing works
Butyrate enhances the intestinal barrier by facilitating tight junction assembly via activation of AMP-activated protein kinase in Caco-2 cell monolayers
Peng, L., Li, Z.-R., Green, R. S., Holzmanr, I. R., & Lin, J. (2009) · The Journal of Nutrition · doi:10.3945/jn.109.104638 · Cited by 2,130 · see citing works
The pros, cons, and many unknowns of probiotics
Suez, J., Zmora, N., Segal, E., & Elinav, E. (2019) · Nature Medicine · doi:10.1038/s41591-019-0439-x · Cited by 1,398 · see citing works
Probiotics, gut microbiota, and their influence on host health and disease
Sánchez, B., Delgado, S., Blanco‐Míguez, A., Lourenço, A., Gueimonde, M., & Margolles, A. (2017) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201600240 · Cited by 1,104 · see citing works
Postbiotics: An Evolving Term within the Functional Foods Field
Aguilar-Toalá, J. E., Garcia-Varela, R., Garcia, H. S., Mata-Haro, V., González-Córdova, A. F., Vallejo-Cordoba, B., & Hernández-Mendoza, A. (2018) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2018.03.009 · Cited by 1,078 · see citing works
Next-generation probiotics: the spectrum from probiotics to live biotherapeutics
O’Toole, P. W., Marchesi, J. R., & Hill, C. (2017) · Nature Microbiology · doi:10.1038/nmicrobiol.2017.57 · Cited by 971 · see citing works
Wall Teichoic Acids of Gram-Positive Bacteria
Brown, S., Santa Maria, J. P., & Walker, S. (2013) · Annual Review of Microbiology · doi:10.1146/annurev-micro-092412-155620 · Cited by 966 · see citing works
Beneficial effects on host energy metabolism of short-chain fatty acids and vitamins produced by commensal and probiotic bacteria
LeBlanc, J. G., Chain, F., Martín, R., Bermúdez‐Humarán, L. G., Courau, S., & Langella, P. (2017) · Microbial Cell Factories · doi:10.1186/s12934-017-0691-z · Cited by 881 · see citing works
Systematic genome assessment of B-vitamin biosynthesis suggests co-operation among gut microbes
Magnúsdóttir, S., Ravcheev, D., de Crécy-Lagard, V., & Thiele, I. (2015) · Frontiers in Genetics · doi:10.3389/fgene.2015.00148 · Cited by 876 · see citing works
Bacteriocins of lactic acid bacteria: Extending the family
Alvarez-Sieiro, P., Montalbán-López, M., Mu, D., & Kuipers, O. P. (2016) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-016-7343-9 · Cited by 729 · see citing works
The immunomodulatory properties of probiotic microorganisms beyond their viability (ghost probiotics: proposal of paraprobiotic concept)
Taverniti, V., & Guglielmetti, S. (2011) · Genes & Nutrition · doi:10.1007/s12263-011-0218-x · Cited by 703 · see citing works
Lactic Acid Bacteria and Their Bacteriocins: Classification, Biosynthesis and Applications against Uropathogens: A Mini-Review
Mokoena, M. P. (2017) · Molecules · doi:10.3390/molecules22081255 · Cited by 674 · see citing works
Evaluation of the Spermatogenic Activity of Polyherbal Formulation in Oligospermic Males
Hussain, S. A., Hameed, A., Nasir, F., Wu, Y., Suleria, H. A. R., & Song, Y. (2018) · BioMed Research International · doi:10.1155/2018/2070895 · Cited by 644 · see citing works
Health Benefits of Heat-Killed (Tyndallized) Probiotics: An Overview
Piqué, N., Berlanga, M., & Miñana-Galbis, D. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20102534 · Cited by 642 · see citing works
Microbiota restoration: natural and supplemented recovery of human microbial communities
Reid, G., Younes, J. A., van der Mei, H. C., Gloor, G. B., Knight, R. D., & Busscher, H. J. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2473 · Cited by 585 · see citing works
Microbial-Derived Butyrate Promotes Epithelial Barrier Function through IL-10 Receptor–Dependent Repression of Claudin-2
Zheng, L., Kelly, C. J., Battista, K. D., Schaefer, R., Lanis, J. M., Alexeev, E. E., Wang, R. X., Onyiah, J. C., Kominsky, D. J., & Colgan, S. P. (2017) · The Journal of Immunology · doi:10.4049/jimmunol.1700105 · Cited by 549 · see citing works
Exopolysaccharides from lactic acid bacteria: perspectives and challenges
Welman, A. D., & Maddox, I. S. (2003) · Trends in biotechnology · doi:10.1016/s0167-7799(03)00107-0 · Cited by 523 · see citing works
Bioactive peptides as natural antioxidants in food products – A review
Lorenzo, J. M., Munekata, P. E. S., Gómez, B., Barba, F. J., Mora, L., Pérez-Santaescolástica, C., & Toldrá, F. (2018) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2018.07.003 · Cited by 503 · see citing works
Secondary bile acids and short chain fatty acids in the colon: a focus on colonic microbiome, cell proliferation, inflammation, and cancer
Zeng, H., Umar, S., Rust, B., Lazarova, D., & Bordonaro, M. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20051214 · Cited by 480 · see citing works
Exopolysaccharides of lactic acid bacteria: Structure, bioactivity and associations: A review
Zhou, Y., Cui, Y., & Qu, X. (2018) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2018.11.093 · Cited by 414 · see citing works
Cell Wall Structure and Function in Lactic Acid Bacteria
Chapot-Chartier, M.-P., & Kulakauskas, S. (2014) · Microbial Cell Factories · doi:10.1186/1475-2859-13-s1-s9 · Cited by 410 · see citing works
A new definition of functional food by FFC: what makes a new definition unique?
Martirosyan, D. M., & Singh, J. (2015) · Functional Foods in Health and Disease · doi:10.31989/ffhd.v5i6.183 · Cited by 407 · see citing works
Optimization and characterization of biosurfactant production by Bacillus subtilis isolates towards microbial enhanced oil recovery applications
Pereira, J. F. B., Gudiña, E. J., Costa, R. M., et al. (2013) · Fuel · doi:10.1016/j.fuel.2013.04.040 · Cited by 381 · see citing works
Probiotic: conceptualization from a new approach
Zendeboodi, F., Khorshidian, N., Mortazavian, A. M., & da Cruz, A. G. (2020) · Current Opinion in Food Science · doi:10.1016/j.cofs.2020.03.009 · Cited by 378 · see citing works
Nutraceuticals and Functional Foods: The Foods for the Future World
Gul, K., Singh, A. K., & Jabeen, R. (2015) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2014.903384 · Cited by 374 · see citing works
Colon microbiota fermentation of dietary prebiotics towards short-chain fatty acids and their roles as anti-inflammatory and antitumour agents: A review
Fernández, J., Redondo-Blanco, S., Gutiérrez‐del‐Río, I., Miguélez, E. M., Villar, C. J., & Lombó, F. (2016) · Journal of Functional Foods · doi:10.1016/j.jff.2016.06.032 · Cited by 373 · see citing works
Probiotic and postbiotic activity in health and disease: comparison on a novel polarised ex-vivo organ culture model
Tsilingiri, K., Barbosa, T., Penna, G., Caprioli, F., Sonzogni, A., Viale, G., & Rescigno, M. (2012) · Gut · doi:10.1136/gutjnl-2011-300971 · Cited by 364 · see citing works
Emerging Health Concepts in the Probiotics Field: Streamlining the Definitions
Martín, R., & Langella, P. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.01047 · Cited by 363 · see citing works
Human-origin probiotic cocktail increases short-chain fatty acid production via modulation of mice and human gut microbiome
Nagpal, R., Wang, S., Ahmadi, S., Hayes, J., Gagliano, J., Subashchandrabose, S., Kitzman, D. W., Becton, T., Read, R., & Yadav, H. (2018) · Scientific Reports · doi:10.1038/s41598-018-30114-4 · Cited by 355 · see citing works
Self-citation
Characterization of Biosurfactant Produced during Degradation of Hydrocarbons Using Crude Oil As Sole Source of Carbon
Patowary, K., Patowary, R., Kalita, M. C., & Deka, S. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.00279 · Cited by 342 · see citing works
Where to Look into the Puzzle of Polyphenols and Health? The Postbiotics and Gut Microbiota Associated with Human Metabotypes
Cortés‐Martín, A., Selma, M. V., Tomás-Barberán, F. A., González‐Sarrías, A., & Espı́n, J. C. (2020) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201900952 · Cited by 305 · see citing works
Probiotic Cell‐Free Supernatants Exhibited Anti‐Inflammatory and Antioxidant Activity on Human Gut Epithelial Cells and Macrophages Stimulated with LPS
De Marco, S., Sichetti, M., Muradyan, D., Piccioni, M., Traina, G., Pagiotti, R., & Pietrella, D. (2018) · Evidence-Based Complementary and Alternative Medicine · doi:10.1155/2018/1756308 · Cited by 297 · see citing works
Short chain fatty acids and colonic health
Hijová, E., & Chmelařová, A. (2007) · Bratislavské lekárske listy/Bratislava medical journal · doi:10.1007/bf03656953 · Cited by 295 · see citing works
Surface-layer protein extracts from Lactobacillus helveticus inhibit enterohaemorrhagic Escherichia coli O157:H7 adhesion to epithelial cells
Johnson-Henry, K. C., Hagen, K. E., Gordonpour, M., Tompkins, T. A., & Sherman, P. M. (2007) · Cellular Microbiology · doi:10.1111/j.1462-5822.2006.00791.x · Cited by 274 · see citing works
Bioprotective mechanisms of lactic acid bacteria against fungal spoilage of food
Siedler, S., Balti, R., & Neves, A. R. (2018) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2018.11.015 · Cited by 243 · see citing works
Identification ofLactobacillus plantarumGenes That Are Induced in the Gastrointestinal Tract of Mice
Bron, P. A., Grangette, C., Mercenier, A., de Vos, W. M., & Kleerebezem, M. (2004) · Journal of Bacteriology · doi:10.1128/jb.186.17.5721-5729.2004 · Cited by 239 · see citing works
Postbiotic metabolites produced by Lactobacillus plantarum strains exert selective cytotoxicity effects on cancer cells
Chuah, L., Foo, H. L., Loh, T. C., Alitheen, N. B., Yeap, S. K., Mutalib, N. E. A., Rahim, R. A., & Yusoff, K. (2019) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-019-2528-2 · Cited by 235 · see citing works
Muramyl Dipeptide-Based Postbiotics Mitigate Obesity-Induced Insulin Resistance via IRF4
Cavallari, J. F., Fullerton, M. D., Duggan, B. M., Foley, K. P., Denou, E., Smith, B. K., Desjardins, E. M., Henriksbo, B. D., Kim, K. J., Tuinema, B. R., et al. (2017) · Cell Metabolism · doi:10.1016/j.cmet.2017.03.021 · Cited by 231 · see citing works
Manifestations of Sasang Typology according to Common Chronic Diseases in Koreans
Hong, S. W., Suh, Y. S., Kim, D. H., Kim, M. K., Kim, H. S., Park, K. S., Hwang, J. S., Shin, S., Cho, C., Jung, S. W., et al. (2018) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2018/7378608 · Cited by 231 · see citing works
Strengthening of the intestinal epithelial tight junction by Bifidobacterium bifidum
Hsieh, C.-Y., Osaka, T., Moriyama, E., Date, Y., Kikuchi, J., & Tsuneda, S. (2015) · Physiological Reports · doi:10.14814/phy2.12327 · Cited by 229 · see citing works
One hundred years of clostridial butanol fermentation
Moon, H. G., Jang, Y., Cho, C., Lee, J., Binkley, R. M., & Lee, S. Y. (2016) · FEMS Microbiology Letters · doi:10.1093/femsle/fnw001 · Cited by 228 · see citing works
Lipoteichoic acid from the cell wall of a heat killed Lactobacillus paracasei D3-5 ameliorates aging-related leaky gut, inflammation and improves physical and cognitive functions: from C. elegans to mice
Wang, S., Ahmadi, S., Nagpal, R., Jain, S., Mishra, S. P., Kavanagh, K., Zhu, X., Wang, Z., McClain, D. A., Kritchevsky, S. B., et al. (2019) · GeroScience · doi:10.1007/s11357-019-00137-4 · Cited by 228 · see citing works
Self-citation
Lactic acid bacteria as a cell factory for riboflavin production
Thakur, K., Tomar, S. K., & De, S. (2015) · Microbial Biotechnology · doi:10.1111/1751-7915.12335 · Cited by 222 · see citing works
Metabiotics: novel idea or natural development of probiotic conception
Ba, S. (2013) · Microbial Ecology in Health and Disease · doi:10.3402/mehd.v24i0.20399 · Cited by 212 · see citing works
Characterization and application of postbiotics of Lactobacillus spp. on Listeria monocytogenes in vitro and in food models
Moradi, M., Mardani, K., & Tajik, H. (2019) · LWT · doi:10.1016/j.lwt.2019.05.072 · Cited by 203 · see citing works
Cell-Free Supernatants from Probiotic Lactobacillus casei and Lactobacillus rhamnosus GG Decrease Colon Cancer Cell Invasion In Vitro
Escamilla, J., Lane, M. A., & Maitin, V. (2012) · Nutrition and Cancer · doi:10.1080/01635581.2012.700758 · Cited by 191 · see citing works
Some current applications, limitations and future perspectives of lactic acid bacteria as probiotics
Evivie, S. E., Huo, G., Igene, J. O., & Bian, X. (2017) · Food & Nutrition Research · doi:10.1080/16546628.2017.1318034 · Cited by 189 · see citing works
Metabiotics: One Step ahead of Probiotics; an Insight into Mechanisms Involved in Anticancerous Effect in Colorectal Cancer
Sharma, M., & Shukla, G. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.01940 · Cited by 187 · see citing works
Bacillus coagulans MTCC 5856 for the management of major depression with irritable bowel syndrome: a randomised, double-blind, placebo controlled, multi-centre, pilot clinical study
Majeed, M. A., Nagabhushanam, K., Arumugam, S., Majeed, S., & Ali, F. H. M. (2018) · Food & Nutrition Research · doi:10.29219/fnr.v62.1218 · Cited by 184 · see citing works
Biological and physicochemical properties of biosurfactants produced by Lactobacillus jensenii P6A and Lactobacillus gasseri P65
Morais, I. M. C., Cordeiro, A. L. S., Teixeira, G. S., Domingues, V. S., Nardi, R. M. D., Monteiro, A. S., Alves, R. J., de Siqueira, E. P., & dos Santos, V. L. (2017) · Microbial Cell Factories · doi:10.1186/s12934-017-0769-7 · Cited by 182 · see citing works
Exopolysaccharides of Lactobacillus rhamnosus GG form a protective shield against innate immune factors in the intestine
Lebeer, S., Claes, I. J. J., Verhoeven, T. L. A., Vanderleyden, J., & Keersmaecker, S. C. J. D. (2010) · Microbial Biotechnology · doi:10.1111/j.1751-7915.2010.00199.x · Cited by 179 · see citing works
Importance of S-layer proteins in probiotic activity of Lactobacillus acidophilus M92
Frece, J., Kos, B., Svetec, I., Zgaga, Z., Mrša, V., & Suskovic, J. (2005) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2004.02473.x · Cited by 179 · see citing works
The Impact of Biosurfactants on Microbial Cell Properties Leading to Hydrocarbon Bioavailability Increase
Kaczorek, E., Pacholak, A., Zdarta, A., & Smułek, W. (2018) · Colloids and Interfaces · doi:10.3390/colloids2030035 · Cited by 179 · see citing works
L. plantarum prevents Enteroinvasive Escherichia coli-induced tight junction proteins changes in intestinal epithelial cells
Qin, H., Zhang, Z., Hang, X., & Jiang, Y. (2009) · BMC Microbiology · doi:10.1186/1471-2180-9-63 · Cited by 175 · see citing works
Surface-bound proteins of Lactobacillus plantarum 423 that contribute to adhesion of Caco-2 cells and their role in competitive exclusion and displacement of Clostridium sporogenes and Enterococcus faecalis
Ramiah, K., van Reenen, C. A., & Dicks, L. M. T. (2008) · Research in Microbiology · doi:10.1016/j.resmic.2008.06.002 · Cited by 174 · see citing works
Biosurfactant/s from Lactobacilli species: Properties, challenges and potential biomedical applications
Satpute, S., Kulkarni, G., Banpurkar, A. G., Banat, I. M., Mone, N. S., Patil, R., & Cameotra, S. S. (2016) · Journal of Basic Microbiology · doi:10.1002/jobm.201600143 · Cited by 172 · see citing works
Sodium Butyrate Promotes Reassembly of Tight Junctions in Caco-2 Monolayers Involving Inhibition of MLCK/MLC2 Pathway and Phosphorylation of PKCβ2
Miao, W., Wu, X., Wang, K., Wang, W., Wang, Y., Li, Z., Liu, J., Li, L., & Peng, L. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17101696 · Cited by 164 · see citing works
Para-probiotics for Preterm Neonates—The Next Frontier
Deshpande, G., Athalye-Jape, G., & Patole, S. (2018) · Nutrients · doi:10.3390/nu10070871 · Cited by 164 · see citing works
Antioxidant and antiproliferative potential of biosurfactants isolated from Lactobacillus casei and their anti-biofilm effect in oral Staphylococcus aureus strains
Merghni, A., Dallel, I., Noumi, E., Kadmi, Y., Hentati, H. A. A., Tobji, S., Amor, A. B., & Mastouri, M. (2017) · Microbial Pathogenesis · doi:10.1016/j.micpath.2017.01.017 · Cited by 162 · see citing works
A new morphologically characterized cell wall preparation (whole peptidoglycan) from Bifidobacterium infantis with a higher efficacy on the regression of an established tumor in mice.
Sekine, K., Toida, T., Saito, M., Kuboyama, M., Kawashima, T., & Hashimoto, Y. (1985) · PubMed · Cited by 153 · see citing works
Live and Heat-Killed Lactobacillus rhamnosus GG: Effects on Proinflammatory and Anti-Inflammatory Cytokines/Chemokines in Gastrostomy-Fed Infant Rats
Li, N., Russell, W. M., Douglas‐Escobar, M., Hauser, N., Lopez, M., & Neu, J. (2009) · Pediatric Research · doi:10.1203/pdr.0b013e3181aabd4f · Cited by 149 · see citing works
Peptidoglycan from lactobacilli inhibits interleukin‐12 production by macrophages induced by Lactobacillus casei through Toll‐like receptor 2‐dependent and independent mechanisms
Shida, K., Kiyoshima‐Shibata, J., Kaji, R., Nagaoka, M., & Nanno, M. (2009) · Immunology · doi:10.1111/j.1365-2567.2009.03095.x · Cited by 136 · see citing works
Production Potency of Folate, Vitamin B12, and Thiamine by Lactic Acid Bacteria Isolated from Japanese Pickles
MASUDA, M., Mariko, I. D. E., Utsumi, H., NIIRO, T., Shimamura, Y., & Murata, M. (2012) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.120414 · Cited by 131 · see citing works
Remodeling of Tight Junctions and Enhancement of Barrier Integrity of the CACO-2 Intestinal Epithelial Cell Layer by Micronutrients
Valenzano, M., Diguilio, K., Mercado, J. M., Teter, M., To, J., Ferraro, B., Mixson, B., Manley, I., Baker, V., Moore, B., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0133926 · Cited by 129 · see citing works
Heat-killed body of lactobacillus brevis SBC8803 ameliorates intestinal injury in a murine model of colitis by enhancing the intestinal barrier function
Ueno, N., Fujiya, M., Segawa, S., Nata, T., Moriichi, K., Tanabe, H., Mizukami, Y., Kobayashi, N., Ito, K., & Kohgo, Y. (2011) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21597 · Cited by 128 · see citing works
Production of natural folates by lactic acid bacteria starter cultures isolated from artisanal Argentinean yogurts
Laiño, J., LeBlanc, J. G., & de Giori, G. S. (2012) · Canadian Journal of Microbiology · doi:10.1139/w2012-026 · Cited by 125 · see citing works
Physicochemical characterization and antitumour activity of exopolysaccharides produced by Lactobacillus casei SB27 from yak milk
Di, W., Zhang, L., Wang, S., Yi, H., Han, X., Fan, R., & Zhang, Y. (2017) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2017.03.018 · Cited by 124 · see citing works
Bacteriocins: Not Only Antibacterial Agents
Drider, D., Bendali, F., Naghmouchi, K., & Chikindas, M. L. (2016) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-016-9223-0 · Cited by 123 · see citing works
Lipoteichoic Acid of Probiotic Lactobacillus plantarum Attenuates Poly I:C-Induced IL-8 Production in Porcine Intestinal Epithelial Cells
Kim, K. W., Kang, S., Woo, S., Park, O.-J., Ahn, K. B., Song, K., Lee, H., Yun, C., & Han, S. H. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.01827 · Cited by 122 · see citing works
Effect of Lactobacillus paracasei CNCM I‐1572 on symptoms, gut microbiota, short chain fatty acids, and immune activation in patients with irritable bowel syndrome: A pilot randomized clinical trial
Cremon, C., Guglielmetti, S., Gargari, G., Taverniti, V., Castellazzi, A. M., Valsecchi, C., Tagliacarne, S. C., Fiore, W., Bellini, M., Bertani, L., et al. (2017) · United European Gastroenterology Journal · doi:10.1177/2050640617736478 · Cited by 118 · see citing works
Cholesterol removal by some lactic acid bacteria that can be used as probiotic
Tok, E., & Aslim, B. (2010) · Microbiology and Immunology · doi:10.1111/j.1348-0421.2010.00219.x · Cited by 117 · see citing works
Potential therapeutic applications of microbial surface-active compounds
Fracchia, L., Banat, J. J., Cavallo, M., Ceresa, C., & Banat, I. M. (2015) · AIMS bioengineering · doi:10.3934/bioeng.2015.3.144 · Cited by 116 · see citing works
Lipoteichoic acid is an important microbe-associated molecular pattern of Lactobacillus rhamnosus GG
Claes, I. J. J., Segers, M. E., Verhoeven, T. L. A., Dusselier, M., Sels, B. F., Keersmaecker, S. C. J. D., Vanderleyden, J., & Lebeer, S. (2012) · Microbial Cell Factories · doi:10.1186/1475-2859-11-161 · Cited by 116 · see citing works
Heat-killed and live Lactobacillus reuteri GMNL-263 exhibit similar effects on improving metabolic functions in high-fat diet-induced obese rats
Hsieh, F.-C., Lan, C.-C. E., Huang, T.-Y., Chen, K., Chai, C., Chen, W., Fang, A.-H., Chen, Y., & Wu, C. (2016) · Food & Function · doi:10.1039/c5fo01396h · Cited by 116 · see citing works
Immunomodulation and signaling mechanism of Lactobacillus rhamnosus GG and its components on porcine intestinal epithelial cells stimulated by lipopolysaccharide
Gao, K., Wang, C., Liu, L., et al. (2015) · Journal of Microbiology Immunology and Infection · doi:10.1016/j.jmii.2015.05.002 · Cited by 115 · see citing works
A review of acrylamide toxicity and its mechanism
Zamani, E., Shokrzadeh, M., Fallah, M., et al. (2017) · Pharmaceutical and Biomedical Research · doi:10.18869/acadpub.pbr.3.1.1 · Cited by 114 · see citing works
Pretreatment with a Heat-Killed Probiotic Modulates the NLRP3 Inflammasome and Attenuates Colitis-Associated Colorectal Cancer in Mice
Chung, I., OuYang, C., Yuan, S.-N., Lin, H., Huang, K., Wu, P., Liu, C., Tsai, K., Loi, L., Chen, Y.-J., et al. (2019) · Nutrients · doi:10.3390/nu11030516 · Cited by 114 · see citing works
Lactobacillus plantarum lipoteichoic acid inhibits biofilm formation of Streptococcus mutans
Ahn, K. B., Baik, J. E., Park, O.-J., Yun, C.-H., & Han, S. H. (2018) · PLOS ONE · doi:10.1371/journal.pone.0192694 · Cited by 113 · see citing works
Influence of electrical properties on the evaluation of the surface hydrophobicity of Bacillus subtilis
Ahimou, F., Paquot, M., Jacques, P., et al. (2001) · Journal of Microbiological Methods · doi:10.1016/s0167-7012(01)00240-8 · Cited by 112 · see citing works
Epigenetic imprinting by commensal probiotics inhibits the IL-23/IL-17 axis in an in vitro model of the intestinal mucosal immune system
Ghadimi, D., Helwig, U., Schrezenmeir, J., Heller, K. J., & de Vrese, M. (2012) · Journal of Leukocyte Biology · doi:10.1189/jlb.0611286 · Cited by 111 · see citing works
Exopolysaccharides produced by Lactobacillus and Bifidobacterium strains abrogate in vitro the cytotoxic effect of bacterial toxins on eukaryotic cells
Ruas‐Madiedo, P., Medrano, M., Salazar, N., Reyes‐Gavilán, C. G. D. L., Pérez, P. F., & Abraham, A. G. (2010) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2010.04839.x · Cited by 110 · see citing works
Preparation, Partial Characterization and Biological Activity of Exopolysaccharides Produced from Lactobacillus fermentum S1
Wang, K., Niu, M., Song, D., Song, X., Zhao, J., Wu, Y., Lu, B., & Niu, G. (2020) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2019.07.009 · Cited by 110 · see citing works
Phage resistance at the cost of virulence: Listeria monocytogenes serovar 4b requires galactosylated teichoic acids for InlB-mediated invasion
Sumrall, E. T., Shen, Y., Keller, A. P., Rismondo, J., Pavlou, M. P., Eugster, M. R., Boulos, S., Disson, O., Thouvenot, P., Kilcher, S., et al. (2019) · PLoS Pathogens · doi:10.1371/journal.ppat.1008032 · Cited by 109 · see citing works
Nutraceutical and Functional Food Regulations in the United States and Around the World
(2014) · Elsevier eBooks · doi:10.1016/c2012-0-00335-3 · Cited by 106 · see citing works
Live and heat-killed probiotic Lactobacillus casei Lbs2 protects from experimental colitis through Toll-like receptor 2-dependent induction of T-regulatory response
Thakur, B. K., Saha, P., Banik, G., Saha, D. R., Grover, S., Batish, V. K., & Das, S. (2016) · International Immunopharmacology · doi:10.1016/j.intimp.2016.03.033 · Cited by 106 · see citing works
Extracellular vesicles and soluble factors secreted by Escherichia coli Nissle 1917 and ECOR63 protect against enteropathogenic E. coli-induced intestinal epithelial barrier dysfunction
Álvarez-Villagómez, C. S., Gíménez, R., Cañas, M.-A., Vera, R., Díaz‐Garrido, N., Badı́a, J., & Baldomà, L. (2019) · BMC Microbiology · doi:10.1186/s12866-019-1534-3 · Cited by 105 · see citing works
Evaluation of Biosurfactant Production from Various Agricultural Residues by Lactobacillus pentosus
Moldes, A. B., Torrado, A., Barral, M. T., & Domínguez, J. M. (2007) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf063075g · Cited by 103 · see citing works
Characterization of Low-Molecular-Weight Antiyeast Metabolites Produced by a Food-Protective Lactobacillus-Propionibacterium Coculture
Schwenninger, S. M., Lacroix, C., Truttmann, S., Jans, C., Spoerndli, C., Bigler, L., & Meile, L. (2008) · Journal of Food Protection · doi:10.4315/0362-028x-71.12.2481 · Cited by 103 · see citing works
Microbial Biosurfactants and their Environmental and Industrial Applications
(2019) · CRC Press eBooks · doi:10.1201/b21950 · Cited by 103 · see citing works
Cytokine responses in the Japanese pufferfish (Takifugu rubripes) head kidney cells induced with heat-killed probiotics isolated from the Mongolian dairy products
Biswas, G., Korenaga, H., Nagamine, R., Takayama, H., Kawahara, S., Takeda, S., Kikuchi, Y., Dashnyam, B., Kono, T., & Sakai, M. (2013) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2013.01.024 · Cited by 101 · see citing works
Peptidoglycan from Immunobiotic Lactobacillus rhamnosus Improves Resistance of Infant Mice to Respiratory Syncytial Viral Infection and Secondary Pneumococcal Pneumonia
Clua, P., Kanmani, P., Zelaya, H., Tada, A., Kober, A. K. M. H., Salva, S., Alvarez, S., Kitazawa, H., & Villena, J. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00948 · Cited by 101 · see citing works
Immune effect of heat-killed multistrain of Lactobacillus acidophilus against Salmonella typhimurium invasion to mice
Lin, W.-H., Yu, B., Lin, C.-K., Hwang, W.-Z., & Tsen, H.-Y. (2006) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2006.03073.x · Cited by 100 · see citing works
Developing bacteriocins of lactic acid bacteria into next generation biopreservatives
Field, D., Ross, R. P., & Hill, C. (2018) · Current Opinion in Food Science · doi:10.1016/j.cofs.2018.02.004 · Cited by 98 · see citing works
Antagonistic Activity of Lactobacillus reuteri Strains on the Adhesion Characteristics of Selected Pathogens
Singh, T. P., Kaur, G., Kapila, S., & Malik, R. K. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.00486 · Cited by 95 · see citing works
Metabiotics: The Functional Metabolic Signatures of Probiotics: Current State-of-Art and Future Research Priorities—Metabiotics: Probiotics Effector Molecules
Singh, A., Vishwakarma, V., & Singhal, B. (2018) · Advances in Bioscience and Biotechnology · doi:10.4236/abb.2018.94012 · Cited by 95 · see citing works
Effects of Oral Administration of Bifidobacterium breve on Fecal Lactic Acid and Short‐chain Fatty Acids in Low Birth Weight Infants
Wang, C., Shoji, H., Sato, H., Nagata, S., Ohtsuka, Y., Shimizu, T., & Yamashiro, Y. (2007) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/01.mpg.0000252184.89922.5f · Cited by 94 · see citing works
Lifestyles and Cardiovascular Prevention in Childhood and Adolescence
Abrignani, M. G., Lucà, F., Favilli, S., Benvenuto, M., Rao, C. M., Fusco, S. A. D., Gabrielli, D., & Gulizia, M. M. (2019) · Pediatric Cardiology · doi:10.1007/s00246-019-02152-w · Cited by 93 · see citing works
Screening of a natural biodiversity of lactic and propionic acid bacteria for folate and vitamin B12 production in supplemented whey permeate
Hugenschmidt, S., Schwenninger, S. M., Gnehm, N., et al. (2010) · International Dairy Journal · doi:10.1016/j.idairyj.2010.05.005 · Cited by 92 · see citing works
Differences between live and heat-killed bifidobacteria in the regulation of immune function and the intestinal environment
Sugahara, H., Yao, R., Odamaki, T., & Xiao, J. (2017) · Beneficial Microbes · doi:10.3920/bm2016.0158 · Cited by 92 · see citing works
Antimicrobial Activity of a Bacteriocin Produced by Enterococcus faecalis KT11 against Some Pathogens and Antibiotic-Resistant Bacteria
Abanoz, H. S., & Kunduhoğlu, B. (2018) · Korean Journal for Food Science of Animal Resources · doi:10.5851/kosfa.2018.e40 · Cited by 91 · see citing works
Co-fermentation of Propionibacterium freudenreichii and Lactobacillus brevis in Wheat Bran for in situ Production of Vitamin B12
Xie, C., Coda, R., Chamlagain, B., Varmanen, P., Piironen, V. I., & Katina, K. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.01541 · Cited by 91 · see citing works
In situ production of active vitamin B12 in cereal matrices using Propionibacterium freudenreichii
Chamlagain, B., Sugito, T. A., Deptula, P., Edelmann, M., Kariluoto, S., Varmanen, P., & Piironen, V. I. (2017) · Food Science & Nutrition · doi:10.1002/fsn3.528 · Cited by 89 · see citing works
Antibacterial and Antibiofilm Activity of Lactic Acid Bacteria Isolated from Traditional Artisanal Milk Cheese from Northeast China Against Enteropathogenic Bacteria
Cui, X., Shi, Y., Gu, S., Yan, X., Chen, H., & Ge, J. (2018) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-017-9364-9 · Cited by 88 · see citing works
Antioxidant effects of live and heat-killed probiotic Lactobacillus plantarum Ln1 isolated from kimchi
Jang, H. J., Song, M. W., Lee, N., & Paik, H. (2018) · Journal of Food Science and Technology · doi:10.1007/s13197-018-3245-4 · Cited by 87 · see citing works
Lipoteichoic Acid Inhibits Staphylococcus aureus Biofilm Formation
Ahn, K. B., Baik, J. E., Yun, C., & Han, S. H. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.00327 · Cited by 85 · see citing works
Anti-tumor potential of cell free culture supernatant of Lactobacillus rhamnosus strains isolated from human breast milk
Rajoka, M. S. R., Zhao, H., Mehwish, H. M., Li, N., Lu, Y. P., Lian, Z., Shao, D., Jin, M., Li, Q., Zhao, L., et al. (2019) · Food Research International · doi:10.1016/j.foodres.2019.05.002 · Cited by 84 · see citing works
Structural diversity and biological significance of lipoteichoic acid in Gram-positive bacteria: focusing on beneficial probiotic lactic acid bacteria
Shiraishi, T., Yokota, S., Fukiya, S., et al. (2016) · Bioscience of Microbiota Food and Health · doi:10.12938/bmfh.2016-006 · Cited by 83 · see citing works
Healthy Foods as Proxy for Functional Foods: Consumers’ Awareness, Perception, and Demand for Natural Functional Foods in Pakistan
Ali, A., & Rahut, D. B. (2019) · International Journal of Food Science · doi:10.1155/2019/6390650 · Cited by 83 · see citing works
Lactobacillus acidophilus DDS-1 Modulates Intestinal-Specific Microbiota, Short-Chain Fatty Acid and Immunological Profiles in Aging Mice
Vemuri, R., Gundamaraju, R., Shinde, T., Perera, A. P., Basheer, W., Southam, B., Gondalia, S. V., Karpe, A. V., Beale, D. J., Tristram, S. G., et al. (2019) · Nutrients · doi:10.3390/nu11061297 · Cited by 83 · see citing works
Liposomes containing biosurfactants isolated from Lactobacillus gasseri exert antibiofilm activity against methicillin resistant Staphylococcus aureus strains
Giordani, B., Costantini, P. E., Fedi, S., Cappelletti, M., Abruzzo, A., Parolin, C., Foschi, C., Frisco, G., Calonghi, N., Cerchiara, T., et al. (2019) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2019.04.011 · Cited by 77 · see citing works
Screening of autochthonous lactic acid bacteria strains from artisanal soft cheese: probiotic characteristics and prebiotic metabolism
Ruiz‐Moyano, S., Santos, M. T., Galván, A. I., Merchán, A. V., González, E., Córdoba, M. D. G., & Benito, M. J. (2019) · LWT · doi:10.1016/j.lwt.2019.108388 · Cited by 75 · see citing works
Surface proteins from Lactobacillus kefir antagonize in vitro cytotoxic effect of Clostridium difficile toxins
Carasi, P., Trejo, F. M., Pérez, P. F., Antoni, G. L. D., & Serradell, M. D. L. Á. (2011) · Anaerobe · doi:10.1016/j.anaerobe.2011.11.002 · Cited by 74 · see citing works
Characterization of Antibacterial Cell-Free Supernatant from Oral Care Probiotic Weissella cibaria, CMU
Lim, H.-S., Yeu, J.-E., Hong, S.-P., & Kang, M. (2018) · Molecules · doi:10.3390/molecules23081984 · Cited by 73 · see citing works
Lipoteichoic acids of lactobacilli inhibit Enterococcus faecalis biofilm formation and disrupt the preformed biofilm
Jung, S., Park, O.-J., Kim, A.-R., et al. (2019) · The Journal of Microbiology · doi:10.1007/s12275-019-8538-4 · Cited by 70 · see citing works
Microbiome and metabolome in diagnosis, therapy, and other strategic applications
Faintuch, J., & Faintuch, S. (2019) · Published in <b>2019</b> · Cited by 70 · see citing works
Are the immunomodulatory properties of Lactobacillus rhamnosus CRL1505 peptidoglycan common for all Lactobacilli during respiratory infection in malnourished mice?
Kolling, Y., Salva, S., Villena, J., & Alvarez, S. (2018) · PLoS ONE · doi:10.1371/journal.pone.0194034 · Cited by 69 · see citing works
Food-Like Growth Conditions Support Production of Active Vitamin B12 by Propionibacterium freudenreichii 2067 without DMBI, the Lower Ligand Base, or Cobalt Supplementation
Deptula, P., Chamlagain, B., Edelmann, M., Sangsuwan, P., Nyman, T. A., Savijoki, K., Piironen, V. I., & Varmanen, P. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.00368 · Cited by 68 · see citing works
Cell-Free Culture Supernatant of Probiotic Lactobacillus fermentum Protects Against H2O2-Induced Premature Senescence by Suppressing ROS-Akt-mTOR Axis in Murine Preadipocytes
Kumar, R., Sharma, A., Gupta, M., Padwad, Y. S., & Sharma, R. (2019) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-019-09576-z · Cited by 67 · see citing works
A Computational Assay of Estrogen Receptor α Antagonists Reveals the Key Common Structural Traits of Drugs Effectively Fighting Refractory Breast Cancers
Pavlin, M., Spinello, A., Pennati, M., Zaffaroni, N., Gobbi, S., Bisi, A., Colombo, G., & Magistrato, A. (2018) · Scientific Reports · doi:10.1038/s41598-017-17364-4 · Cited by 66 · see citing works
Inhibition of uropathogenic biofilm growth on silicone rubber in human urine by lactobacilli – a teleologic approach
de Vries, M., van de Belt‐Gritter, B., Busscher, H. J., et al. (2000) · World Journal of Urology · doi:10.1007/pl00007084 · Cited by 65 · see citing works
Assessment of anti-biofilm activity and bifidogenic growth stimulator (BGS) effect of lyophilized exopolysaccharides (l-EPSs) from <i>Lactobacilli</i> strains
Sarikaya, H., Aslim, B., & Yuksekdag, Z. (2017) · International Journal of Food Properties · doi:10.1080/10942912.2016.1160923 · Cited by 65 · see citing works
Exopolysaccharides from Lactobacillus buchneri TCP016 Attenuate LPS- and d -GalN-Induced Liver Injury by Modulating the Gut Microbiota
Xu, R., Aruhan, Xiu, L., Sheng, S., Liang, Y., Zhang, H. C., Liu, Y., He, T., Du, R., & Wang, X. (2019) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.9b04323 · Cited by 65 · see citing works
Biosurfactants: promising bioactive molecules for oral-related health applications
Elshikh, M. S., Marchant, R., & Banat, I. M. (2016) · FEMS Microbiology Letters · doi:10.1093/femsle/fnw213 · Cited by 64 · see citing works
Effects of Lactic Acid Bacteria‐Fermented Soymilk on Isoflavone Metabolites and Short‐Chain Fatty Acids Excretion and Their Modulating Effects on Gut Microbiota
Dai, S., Pan, M., El-Nezami, H. S., Wan, J., Wang, M., Habimana, O., Lee, J. C., Louie, J. C. Y., & Shah, N. P. (2019) · Journal of Food Science · doi:10.1111/1750-3841.14661 · Cited by 63 · see citing works
Bioactive Compounds as Ingredients of Functional Foods
Fernandes, S. S., Coelho, M. S., & Salas‐Mellado, M. D. L. M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-814774-0.00007-4 · Cited by 62 · see citing works
Probiotic Properties of Lyophilized Cell Free Extract of Lactobacillus casei
Saadatzadeh, A., Fazeli, M. R., Jamalifar, H., & Dinarvand, R. (2013) · Jundishapur Journal of Natural Pharmaceutical Products · doi:10.17795/jjnpp-8564 · Cited by 61 · see citing works
Functional Food Consumption and Its Physiological Effects
Aguiar, L. M., Geraldi, M. V., Cazarin, C. B. B., & Maróstica, M. R. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-814774-0.00011-6 · Cited by 59 · see citing works
Lactobacillus plantarum surface layer adhesive protein protects intestinal epithelial cells against tight junction injury induced by enteropathogenic Escherichia coli
Liu, Z., Shen, T., Zhang, P., Ma, Y., & Qin, H. (2010) · Molecular Biology Reports · doi:10.1007/s11033-010-0457-8 · Cited by 58 · see citing works
Characterization of the Cholesterol-Reducing Activity in a Cell-Free Supernatant ofLactobacillus acidophilusATCC 43121
Kim, Y., WHANG, J. Y., Whang, K. Y., Oh, S., & Kim, S. H. (2008) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.70802 · Cited by 58 · see citing works
Bacterial Probiotics their Importances and Limitations: A Review
Teshale, A., Belete, A., Alebachew, T., Tsehaye, H., Berhanu, H., & Minwuyelet, A. (2017) · Journal of Nutrition and Health Sciences · doi:10.15744/2393-9060.4.202 · Cited by 58 · see citing works
Exopolysaccharides producing Lactobacillus fermentum strain for enhancing rheological and sensory attributes of low-fat dahi
Behare, P. V., Singh, R., Nagpal, R., & Rao, K. H. (2013) · Journal of Food Science and Technology · doi:10.1007/s13197-013-0999-6 · Cited by 57 · see citing works
Self-citation
Mechanistic insights into the action of probiotics against bacterial vaginosis and its mediated preterm birth: An overview
Basavaprabhu, H. N., Shivanna, S. K., & Prabha, R. (2020) · Microbial Pathogenesis · doi:10.1016/j.micpath.2020.104029 · Cited by 57 · see citing works
Lactobacillus plantarum Lipoteichoic Acid Inhibits Oral Multispecies Biofilm
Kim, A. R., Ahn, K. B., Yun, C.-H., Park, O.-J., Perinpanayagam, H., Yoo, Y.-J., Kum, K.-Y., & Han, S. H. (2019) · Journal of Endodontics · doi:10.1016/j.joen.2018.12.007 · Cited by 56 · see citing works
Lactobacillus rhamnosus GG supernatant enhance neonatal resistance to systemic Escherichia coli K1 infection by accelerating development of intestinal defense
He, X., Zeng, Q., Puthiyakunnon, S., Zeng, Z., Yang, W., Qiu, J., Du, L., Boddu, S., Wu, T., Cai, D., et al. (2017) · Scientific Reports · doi:10.1038/srep43305 · Cited by 54 · see citing works
Ability of Lactobacillus plantarum lipoteichoic acid to inhibit Vibrio anguillarum-induced inflammation and apoptosis in silvery pomfret (Pampus argenteus) intestinal epithelial cells
Gao, Q., Gao, Q. X., Min, M., et al. (2016) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2016.05.013 · Cited by 53 · see citing works
Molecular Aspects of Dendritic Cell Activation in Leishmaniasis: An Immunobiological View
Tibúrcio, R., Nunes, S., Nunes, I. V., Ampuero, M. R., Bonyek-Silva, Í., Lima, R., Tavares, N. M., & Brodskyn, C. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00227 · Cited by 53 · see citing works
Mechanistic insights into the host-microbe interaction and pathogen exclusion mediated by the Mucus-binding protein of Lactobacillus plantarum
Singh, K. S., Kumar, S., Mohanty, A. K., Grover, S., & Kaushik, J. K. (2018) · Scientific Reports · doi:10.1038/s41598-018-32417-y · Cited by 52 · see citing works
Use of Gas Chromatography to Quantify Short Chain Fatty Acids in the Serum, Colonic Luminal Content and Feces of Mice
Ribeiro, W. R., Vinolo, M. A. R., Calixto, L. A., et al. (2018) · BIO-PROTOCOL · doi:10.21769/bioprotoc.3089 · Cited by 52 · see citing works
Assessment of the inhibitory effect of free and encapsulated commercial nisin (Nisaplin®), tested alone and in combination, on Listeria monocytogenes and Bacillus cereus in refrigerated milk
Martinez, R. C. R., Alvarenga, V. O., Thomazini, M., et al. (2015) · LWT · doi:10.1016/j.lwt.2015.12.027 · Cited by 51 · see citing works
Live and heat-killed Lactobacillus spp. interfere with Streptococcus mutans and Streptococcus oralis during biofilm development on titanium surface.
Ciandrini, E., Campana, R., & Baffone, W. (2017) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2017.02.004 · Cited by 51 · see citing works
Antibiofilm potential of Lactobacillus plantarum spp. cell free supernatant (CFS) against multidrug resistant bacterial pathogens
Zamani, H., Rahbar, S., Garakoui, S. R., Sahebi, A. A., & Jafari, H. (2017) · Pharmaceutical and Biomedical Research · doi:10.29252/pbr.3.2.39 · Cited by 51 · see citing works
“Postbiotics” - One Step Ahead of Probiotics
Malashree, L., Angadi, V., Yadav, K. S., et al. (2019) · International Journal of Current Microbiology and Applied Sciences · doi:10.20546/ijcmas.2019.801.214 · Cited by 51 · see citing works
Proteomics for the Investigation of Surface-Exposed Proteins in Probiotics
Siciliano, R. A., Lippolis, R., & Mazzeo, M. F. (2019) · Frontiers in Nutrition · doi:10.3389/fnut.2019.00052 · Cited by 51 · see citing works
Cell-Free Supernatants Obtained from Fermentation of Cheese Whey Hydrolyzates and Phenylpyruvic Acid by Lactobacillus plantarum as a Source of Antimicrobial Compounds, Bacteriocins, and Natural Aromas
Rodríguez-Pazo, N., Vázquez‐Araújo, L., Pérez-Rodríguez, N., Cortés‐Diéguez, S., & Domínguez, J. M. (2013) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-013-0408-7 · Cited by 50 · see citing works
Anti-bacterial susceptibility profiling of Weissella confusa DD_A7 against the multidrug-resistant ESBL-positive E. coli
Dey, D. K., Khan, I., & Kang, S. C. (2018) · Microbial Pathogenesis · doi:10.1016/j.micpath.2018.12.048 · Cited by 50 · see citing works
Editorial: Next-Generation Probiotics: From Commensal Bacteria to Novel Drugs and Food Supplements
Langella, P., Guarner, F., & Martín, R. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.01973 · Cited by 50 · see citing works
Efficacy of indigenous probiotic Lactobacillus strains to reduce cadmium bioaccessibility - An in vitro digestion model
Kumar, N., Kumar, V., Panwar, R., et al. (2016) · Environmental Science and Pollution Research · doi:10.1007/s11356-016-7779-6 · Cited by 49 · see citing works
Characterization of biosurfactants produced by the oil-degrading bacterium Rhodococcus erythropolis S67 at low temperature
Luong, T. M., Понаморева, О. Н., Нечаева, И. А., et al. (2018) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-017-2401-8 · Cited by 48 · see citing works
On Lactococcus lactis UL719 competitivity and nisin (Nisaplin®) capacity to inhibit Clostridium difficile in a model of human colon
Lay, C., Fernandez, B., Hammami, R., et al. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.01020 · Cited by 46 · see citing works
Heat-killed Bifidobacterium animalis subsp. Lactis CECT 8145 increases lean mass and ameliorates metabolic syndrome in cafeteria-fed obese rats
Caimari, A., Bas-Prior, J. M. D., Boqué, N., Crescenti, A., Puiggròs, F., Chenoll, E., Martorell, P., Ramón, D., Genovés, S., & Arola, L. (2017) · Journal of Functional Foods · doi:10.1016/j.jff.2017.09.029 · Cited by 46 · see citing works
Validated Postbiotic Screening Confirms Presence of Physiologically-Active Metabolites, Such as Short-Chain Fatty Acids, Amino Acids and Vitamins in Hylak® Forte
Patil, S. V., Sawant, S., Maier-Hauff, K., & Hampp, G. (2018) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-018-9497-5 · Cited by 44 · see citing works
Heat-killed VSL#3 Ameliorates Dextran Sulfate Sodium (DSS)-Induced Acute Experimental Colitis in Rats
Sang, L.-X., Chang, B., Dai, C., Gao, N., Liu, W., & Jiang, M. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms15010015 · Cited by 42 · see citing works
Heat-killed Lactobacillus casei subsp. casei 327 promotes colonic serotonin synthesis in mice
Hara, T., Mihara, T., Ishibashi, M., Kumagai, T., & Joh, T. (2018) · Journal of Functional Foods · doi:10.1016/j.jff.2018.05.050 · Cited by 42 · see citing works
The switch between acute and persistent paramyxovirus infection caused by single amino acid substitutions in the RNA polymerase P subunit
Young, D. F., Wignall-Fleming, E. B., Busse, D. C., Pickin, M. J., Hankinson, J., Randall, E. M., Tavendale, A., Davison, A. J., Lamont, D. J., Tregoning, J. S., et al. (2019) · PLoS Pathogens · doi:10.1371/journal.ppat.1007561 · Cited by 42 · see citing works
The S-layer Associated Serine Protease Homolog PrtX Impacts Cell Surface-Mediated Microbe-Host Interactions of Lactobacillus acidophilus NCFM
Johnson, B. R., O’Flaherty, S., Goh, Y. J., Carroll, I. M., Barrangou, R., & Klaenhammer, T. R. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.01185 · Cited by 41 · see citing works
Characterization of Exopolysaccharides Produced by Thermophilic Lactic Acid Bacteria Isolated from Tropical Fruits of Thailand
Panthavee, W., Noda, M., Danshiitsoodol, N., Kumagai, T., & Sugiyama, M. (2017) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b16-00856 · Cited by 40 · see citing works
Effects of Pediococcus parvulus 2.6 and Its Exopolysaccharide on Plasma Cholesterol Levels and Inflammatory Markers in Mice
Lindström, C., Holst, O., Nilsson, L., Öste, R., & Andersson, K. E. (2012) · AMB Express · doi:10.1186/2191-0855-2-66 · Cited by 38 · see citing works
Whole Peptidoglycan Extracts from theLactobacillus paracaseisubsp.paracaseiM5 Strain Exert Anticancer ActivityIn Vitro
Wang, S., Han, X., Zhang, L., Zhang, Y., Li, H., & Jiao, Y. (2018) · BioMed Research International · doi:10.1155/2018/2871710 · Cited by 38 · see citing works
Effects of oral administration of Bifidobacterium breve on fecal lactic acid and short-chain fatty acids in low-birth-weight infants
王, 崇. (2007) · Medical Entomology and Zoology · Cited by 38 · see citing works
Invited review: Application of omics tools to understanding probiotic functionality
Baugher, J., & Klaenhammer, T. R. (2011) · Journal of Dairy Science · doi:10.3168/jds.2011-4384 · Cited by 37 · see citing works
Invitro study of riboflavin producing lactobacilli as potential probiotic
Thakur, K., & Tomar, S. K. (2015) · LWT · doi:10.1016/j.lwt.2015.12.059 · Cited by 37 · see citing works
Effect of microGARD on keeping quality of direct acidified Cottage cheese
Makhal, S., Kanawjia, S. K., & Giri, A. (2013) · Journal of Food Science and Technology · doi:10.1007/s13197-013-1055-2 · Cited by 36 · see citing works
Nutraceutical and Functional Food Regulations in the United States and Around the World
Turner-Ravana, N. (2020) · Journal of Nutrition Education and Behavior · doi:10.1016/j.jneb.2020.02.001 · Cited by 35 · see citing works
Exopolysaccharide-Producing Mesophilic Lactic Cultures for Preparation of Fat-Free Dahi-an Indian Fermented Milk
Behare, P., Singh, R., & Singh, R. P. (2009) · Journal of Dairy Research · doi:10.1017/s0022029908003865 · Cited by 34 · see citing works
Lactobacillus S-layer protein inhibition of Salmonella-induced reorganization of the cytoskeleton and activation of MAPK signalling pathways in Caco-2 cells
Li, P., Yu, Q., Ye, X., Wang, Z., & Yang, Q. (2011) · Microbiology · doi:10.1099/mic.0.049148-0 · Cited by 34 · see citing works
Lipoteichoic acid synthesis inhibition in combination with antibiotics abrogates growth of multidrug-resistant Enterococcus faecium
Paganelli, F. L., van de Kamer, T., Brouwer, E. C., Leavis, H. L., Woodford, N., Bonten, M. J. M., Willems, R. J. L., & Hendrickx, A. P. A. (2017) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2016.12.002 · Cited by 34 · see citing works
Lipoteichoic Acid Isolated from Lactobacillus plantarum Maintains Inflammatory Homeostasis through Regulation of Th1- and Th2- Induced Cytokines
Ahn, J. E., Kim, H., & Chung, D. K. (2019) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.1809.09001 · Cited by 33 · see citing works
Probiotic lactobacilli mediated changes in global epigenetic signatures of human intestinal epithelial cells during Escherichia coli challenge
Bhat, M. I., Kumari, A., Kapila, S., & Kapila, R. (2019) · Annals of Microbiology · doi:10.1007/s13213-019-01451-0 · Cited by 33 · see citing works
Folate Production by Lactic Acid Bacteria
de Giori, G. S., & LeBlanc, J. G. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813008-7.00002-3 · Cited by 32 · see citing works
Intestinal Microbiota-Associated Metabolites: Crucial Factors in the Effectiveness of Herbal Medicines and Diet Therapies
Wang, Y., Qin, S., Jia, J., Huang, L., Li, F., Jin, F., Ren, Z., & Wang, Y. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.01343 · Cited by 32 · see citing works
Isolation, screening and characterization of riboflavin producing lactic acid bacteria from Katpadi, Vellore district
Jayashree, S., Jayaraman, K., & Gurumurthy, K. (2010) · Recent Research in Science and Technology · Cited by 31 · see citing works
High-resolution mass spectrometry-based global proteomic analysis of probiotic strains Lactobacillus fermentum NCDC 400 and RS2
Parijat, P., Kaur, G., Ali, S. A., Shveta, B., Rawat, P., Lule, V. K., Kumar, S., Mohanty, A. K., & Behare, P. V. (2016) · Journal of Proteomics · doi:10.1016/j.jprot.2016.10.016 · Cited by 30 · see citing works
Self-citation
Phenotypic and genotypic screening of human-originated lactobacilli for vitamin B12 production potential: process validation by micro-assay and UFLC
Bhushan, B., Tomar, S. K., & Mandal, S. (2016) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-016-7639-9 · Cited by 28 · see citing works
The Myth and Therapeutic Potentials of Postbiotics
Foo, H. L., Loh, T. C., Mutalib, N. E. A., & Rahim, R. A. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-815249-2.00021-x · Cited by 27 · see citing works
Impairment of Cronobacter sakazakii and Listeria monocytogenes biofilms by cell-free preparations of lactobacilli of goat milk origin
Singh, N., Kaur, R., Singh, B. P., Rokana, N., Goel, G., Puniya, A. K., & Panwar, H. (2019) · Folia Microbiologica · doi:10.1007/s12223-019-00721-3 · Cited by 27 · see citing works
Antitumoural activity of a cytotoxic peptide of Lactobacillus casei peptidoglycan and its interaction with mitochondrial-bound hexokinase
Fichera, G. A., Fichera, M., & Milone, G. (2016) · Anti-Cancer Drugs · doi:10.1097/cad.0000000000000367 · Cited by 25 · see citing works
Anti-adhesion of probiotic Enterococcus faecium WEFA23 against five pathogens and the beneficial effect of its S-layer proteins against Listeria monocytogenes
He, Y., Xu, X., Zhang, F., Xu, D., Liu, Z., Tao, X., & Wei, H. (2018) · Canadian Journal of Microbiology · doi:10.1139/cjm-2018-0031 · Cited by 24 · see citing works
Prevention of necrotizing enterocolitis through surface layer protein of Lactobacillus acidophilus CICC6074 reducing intestinal epithelial apoptosis
Guo, Y., Jiang, X., Yang, Y., Zhang, J., Zeng, X., Wu, Z. F., Sun, Y., & Pan, D. (2018) · Journal of Functional Foods · doi:10.1016/j.jff.2018.05.045 · Cited by 22 · see citing works
In vitroandin vivodownregulation of C3 by lipoteichoic acid isolated fromLactobacillus plantarumK8 suppressed cytokine-mediated complement system activation
Jeon, B., Kim, H. R., Kim, H., & Chung, D. K. (2016) · FEMS Microbiology Letters · doi:10.1093/femsle/fnw140 · Cited by 21 · see citing works
Oral administration of heat-killed Lactobacillus brevis SBC8803 elevates the ratio of acyl/des-acyl ghrelin in blood and increases short-term food intake
Saito, H., Nakakita, Y., Segawa, S., & Tsuchiya, Y. (2019) · Beneficial Microbes · doi:10.3920/bm2018.0091 · Cited by 21 · see citing works
Effects of Lactobacillus rhamnosus GG and Escherichia coli Nissle 1917 Cell‐Free Supernatants on Modulation of Mucin and Cytokine Secretion on Human Intestinal Epithelial HT29‐MTX Cells
Wan, M. L. Y., Chen, Z., Shah, N. P., & El-Nezami, H. S. (2018) · Journal of Food Science · doi:10.1111/1750-3841.14168 · Cited by 20 · see citing works
Isolation of exopolysaccharides producing lactic acid bacteria from dairy products
Patil, P., Wadehra, A., Munjal, K., & Behare, P. V. (2015) · Asian Journal of Dairy and Food Research · doi:10.18805/ajdfr.v34i4.6878 · Cited by 18 · see citing works
Self-citation
Bioprocessing Technology in Food and Health: Potential Applications and Emerging Scope
Verma, D. K., Patel, A. R., & Srivastav, P. P. (2018) · Apple Academic Press eBooks · doi:10.1201/9781351167888 · Cited by 18 · see citing works
Comparison of exopolysaccharide production by indigenousLeuconostoc mesenteroidesstrains in whey medium
Lule, V. K., Singh, R., Behare, P. V., et al. (2015) · Asian Journal of Dairy and Food Research · doi:10.5958/0976-0563.2015.00002.0 · Cited by 17 · see citing works
Self-citation
Isolation of Biosurfactant from Lactobacillus sp. and Study of Its Inhibitory Properties Against E.coli Biofilm
Emmanuel, E. S. C., Priya, S. S., & George, S. (2019) · Journal of Pure and Applied Microbiology · doi:10.22207/jpam.13.1.44 · Cited by 17 · see citing works
Effect of Lactobacillus rhamnosus GR-1 Supernatant on Cytokine and Chemokine Output From Human Amnion Cells Treated With Lipoteichoic Acid and Lipopolysaccharide
Koscik, R., Reid, G., Kim, S., Li, W., Challis, J., & Bocking, A. (2018) · Reproductive Sciences · doi:10.1177/1933719117711259 · Cited by 16 · see citing works
Plasma Folate, Vitamin B6 and B12 in Their Relationship to the Presence of Probiotic Strain Bifidobacterium animalis subsp. Lactis HNO19 (DR10TM) Among Indonesian Pregnant Women in Their Third Semester
Bardosono, S., Wibowo, N., Sutanto, L. B., et al. (2019) · World Nutrition Journal · doi:10.25220/wnj.v02.i2.0009 · Cited by 16 · see citing works
Preliminary characterization and inhibitory activity of bacteriocin like substances from Lactobacillus casei against multi-drug resistant bacteria
Hasan, F. B., Reza, M., Masud, H. M. A. A., et al. (2019) · Bangladesh Journal of Microbiology · doi:10.3329/bjm.v36i1.44259 · Cited by 15 · see citing works
Quantification of live Lactobacillus acidophilus in mixed populations of live and killed by application of attenuated reflection Fourier transform infrared spectroscopy combined with chemometrics
Toziou, P.-M., Barmpalexis, P., Boukouvala, P., et al. (2018) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2018.03.009 · Cited by 14 · see citing works
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Das, J. K., Mahapatra, R. K., Patro, S., Goswami, C., & Suar, M. (2016) · FEMS Microbiology Letters · doi:10.1093/femsle/fnw050 · Cited by 13 · see citing works
Melioration in Anti-staphylococcal Activity of Conventional Antibiotic(s) by Organic Acids Present in the Cell Free Supernatant of Lactobacillus paraplantarum
Rishi, L., Mittal, G., Agarwal, R. K., et al. (2017) · Indian Journal of Microbiology · doi:10.1007/s12088-017-0659-z · Cited by 12 · see citing works
Downstream Processing of Microbial Biosurfactants
Thavasi, R., & Banat, I. M. (2019) · CRC Press eBooks · doi:10.1201/b21950-2 · Cited by 12 · see citing works
Probiotic foods for human health: A review
Kisan, B., Kumar, R., Ashok, S. P., et al. (2019) · Journal of Pharmacognosy and Phytochemistry · Cited by 12 · see citing works
The Effect of Lactobacillus Plantarum and Bacterial Peptidoglycan on the Growth of Mouse Tumors in vivo and in vitro
Aintablian, A., Jaber, D. F., Jallad, M. A., & Abdelnoor, A. M. (2017) · American Journal of Immunology · doi:10.3844/ajisp.2017.201.208 · Cited by 10 · see citing works
Assessing biodegradation of furfuryl alcohol using Pseudomonas putida MTCC 1194 and Pseudomonas aeruginosa MTCC 1034 and its kinetics
Kumar, R., & Rashmi, D. (2017) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-017-2384-5 · Cited by 10 · see citing works
Evaluating prebiotic property of galactooligosaccharide produced by Lactobacillus pentosus var. plantarum BFP32 in fecal batch culture.
Wichienchot, S., Hemmaratchirakul, J., Jaturapiree, P., et al. (2016) · International Food Research Journal · Cited by 9 · see citing works

Flagged first, then by citations

Research works printed but not linked: 5

[67]Kaur HP Prasad B Kaur S A review on applications of biosurfactants produced from unconventional inexpensive wastes in food and agriculture Industry World J Pharm Res. 2015 4 827 842
[131]De Marco S Sichetti M Muradyan D Piccioni M Traina G Pagiotti R Pietrella D Probiotic cell-free supernatants exhibited anti-inflammatory and antioxidant activity on human gut epithelial cells and macrophages stimulated with LPS Evid Based Complementary Alternative Med 2018 2018 1 12 PMC6057331 30069221
[189]Wang K Niu M Song D Song X Zhao J Wu Y Lu B Niu G Preparation, partial characterization and biological activity of exopolysaccharides produced from Lactobacillus fermentum S1 J Biosci Bioeng 2019 129 26 214 31471140
[190]Merghni A Dallel I Noumi E Kadmi Y Hentati H Tobji S Amor AB Mastouri M Antioxidant and antiproliferative potential of biosurfactants isolated from Lactobacillus casei and their anti-biofilm effect in oral Staphylococcus aureus strains Microb Pathog 2017 104 84 89 28087493
[200]Nagpal R Wang S Ahmadi S Hayes J Gagliano J Subashchandrabose S Kitzman DW Becton T Read R Yadav H Human-origin probiotic cocktail increases short-chain fatty acid production via modulation of mice and human gut microbiome Sci Rep. 2018 8 649 30139941 PMC6107516

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Tong, Y., Guo, H., Abbas, Z., Zhang, J., Wang, J., Cheng, Q., Peng, S., Yang, T., Bai, T., Zhou, Y., et al. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1229952 · Cited by 70 · see citing works
Postbiotics as potential new therapeutic agents for sepsis
Lou, X., Xue, J., Shao, R., Mo, C., Wang, F., & Chen, G. (2023) · Burns & Trauma · doi:10.1093/burnst/tkad022 · Cited by 38 · see citing works
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Karaca, B., Haliscelik, O., Gursoy, M., Kiran, F., Loimaranta, V., Söderling, E., & Gursoy, U. K. (2022) · Microorganisms · doi:10.3390/microorganisms10112200 · Cited by 26 · see citing works
“Several LAB species, particularly those of the genus Lactobacillus, are capable of producing EPSs, and some of the EPSs identified to date by LAB have been shown to have biological functions, such as free radical scavenging, free cholesterol binding, gut microbiota modulation, antitumor, antimicrobial, and antibiofilm…”
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Strain-specific metabolomic diversity of Lactiplantibacillus plantarum under aerobic and anaerobic conditions
Kim, S.-H., Singh, D., Kim, S.-A., Kwak, M. J., Cho, D., Kim, J., Roh, J.-H., Kim, W.-G., Han, N. S., & Lee, C. H. (2023) · Food Microbiology · doi:10.1016/j.fm.2023.104364 · Cited by 12 · see citing works

Structure of the Bacterial Cell Wall.
Umeda, A., & Amako, K. (1998) · Nippon Ishinkin Gakkai Zasshi · doi:10.3314/jjmm.39.147 · Cited by 7 · see citing works
Activation of the Alternative Complement Pathway by Pneumococcal Cell Wall Teichoic Acid
Winkelstein, J. A., & Tomasz, A. (1978) · The Journal of Immunology · doi:10.4049/jimmunol.120.1.174 · Cited by 150 · see citing works
Molecular Arrangement of Teichoic Acid in the Cell Wall of Staphylococcus lactis
Archibald, A. R., BADDILEY, J., & Heckels, J. E. (1973) · Nature New Biology · doi:10.1038/newbio241029a0 · Cited by 31 · see citing works
Teichoic acids anchor distinct cell wall lamellae in an apically growing bacterium
Ultee, E., van der Aart, L. T., Zhang, L., van Dissel, D., Diebolder, C. A., van Wezel, G. P., Claessen, D., & Briegel, A. (2020) · Communications Biology · doi:10.1038/s42003-020-1038-6 · Cited by 33 · see citing works
Dissecting the Bacterial Cell Wall with Solid-State NMR
Romaniuk, J. A. H., & Cegelski, L. (2018) · Biophysical Journal · doi:10.1016/j.bpj.2017.11.885 · Cited by 2 · see citing works

Authors: Nataraj, B. H., Ali, S. A., Behare, P. V., & Yadav, H.
Affiliations: National Dairy Research Institute (IN)
Wake Forest University Health Sciences (US)
Corresponding author: Behare, Pradip V.
Yadav, Hariom
ORCID: Nataraj, Basavaprabhu H.
Ali, Syed Azmal
Behare, Pradip V.
Yadav, Hariom
Venue: Microbial Cell Factories
Publisher: Springer Science and Business Media LLC
Published: 2020-08-20
Volume: 19
Issue: 1
Pages: 168-168
ISSN: 1475-2859 (ISSN-L)
DOI: 10.1186/s12934-020-01426-w
PMC: PMC7441679
OpenAlex: W3059301501
Cited by: 737
References: 210
Citations by year: 2026: 124 · 2025: 150 · 2024: 165 · 2023: 118 · 2022: 117 · 2021: 59 · 2020: 3
FWCI: 6.27
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
creativecommons.org/licenses/by/4.0 (tdm)
creativecommons.org/licenses/by/4.0 (vor)
Locations: Microbial Cell Factories (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders: National Institutes of Health (R01AG018915, P30AG21332, UL1TR001420)
Congressionally Directed Medical Research Programs (W81XWH-19-1-0236)
Topics: Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Hydrolysis and Bioactive Peptides
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Keywords: postbiotics, paraprobiotics, probiotics, functional foods, cell-free supernatant, microbial metabolites, short-chain fatty acids, biosurfactants, peptidoglycan, teichoic acid, pattern recognition receptors, microbe-associated molecular patterns, health-promoting properties
MeSH terms: Gastrointestinal Microbiome, Bacteria, Biological Products, Biological Therapy, Insurance Benefits, Probiotics, Microbial Viability, Functional Food

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Postbiotics-Parabiotics: The New Horizons in Microbial Biotherapy and Functional Foods

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