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Melatonin improves glucose homeostasis in young Zucker diabetic fatty rats
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Abstract: The aim of this study was to investigate the effects of melatonin on glucose homeostasis in young male Zucker diabetic fatty (ZDF) rats, an experimental model of metabolic syndrome and type 2 diabetes mellitus (T2DM). ZDF rats (n = 30) and lean littermates (ZL) (n = 30) were used. At 6 wk of age, both lean and fatty animals were subdivided into three groups, each composed of ten rats: naive (N), vehicle treated (V), and melatonin treated (M) (10 mg/kg/day) for 6 wk. Vehicle and melatonin were added to the drinking water. ZDF rats developed DM (fasting hyperglycemia, 460 ± 39.8 mg/dL; HbA 1 c 8.3 ± 0.5%) with both insulin resistance (HOMA‐IR 9.28 ± 0.9 versus 1.2 ± 0.1 in ZL) and decreased β‐cell function (HOMA1‐%B) by 75%, compared with ZL rats. Melatonin reduced fasting hyperglycemia by 18.6% (P < 0.05) and HbA 1 c by 11% (P < 0.05) in ZDF rats. Also, melatonin lowered insulinemia by 15.9% (P < 0.05) and HOMA‐IR by 31% (P < 0.01) and increased HOMA1‐%B by 14.4% (P < 0.05). In addition, melatonin decreased hyperleptinemia by 34% (P < 0.001) and raised hypoadiponectinemia by 40% (P < 0.001) in ZDF rats. Moreover, melatonin reduced serum free fatty acid levels by 13.5% (P < 0.05). These data demonstrate that oral melatonin administration ameliorates glucose homeostasis in young ZDF rats by improving both insulin action and β‐cell function. These observations have implications on melatonin’s possible use as a new pharmacologic therapy for improving glucose homeostasis and of obesity‐related T2DM, in young subjects.
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“Therefore, although associations of cortisol and melatonin concentrations to insulin action have been reported in the literature (29,30), we did not find such a link in the present study.”
From Diurnal Pattern of Insulin Action in Type 1 Diabetes (2013) · cites this paper as [30]
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Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., & Turner, R. C. (1985) · Diabetologia · doi:10.1007/bf00280883 · Cited by 31,502
Pineal Melatonin: Cell Biology of Its Synthesis and of Its Physiological Interactions*
REITER, R. J. (1991) · Endocrine Reviews · doi:10.1210/edrv-12-2-151 · Cited by 2,192
Melatonin : a potent, endogenous hydroxyl radical scavenger
Tan, D. (1993) · Endocrine Journal · Cited by 1,659
Adiponectin and Metabolic Syndrome
Matsuzawa, Y., Funahashi, T., Kihara, S., & Shimomura, I. (2003) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000099786.99623.ef · Cited by 1,203
Melatonin as a natural ally against oxidative stress: a physicochemical examination
Galano, A., Tan, D. X., & Reiter, R. J. (2011) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2011.00916.x · Cited by 1,167
Kim, J. B., Sarraf, P., Wright, M., Yao, K., Mueller, E., Solanes, G., Lowell, B. B., & Spiegelman, B. M. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1411 · Cited by 792
Adiponectin as a Biomarker of the Metabolic Syndrome
Ryo, M., Nakamura, T., Kihara, S., Kumada, M., Shibazaki, S., Takahashi, M., Nagai, M., Matsuzawa, Y., & Funahashi, T. (2004) · Circulation Journal · doi:10.1253/circj.68.975 · Cited by 777
Adipokines: The missing link between insulin resistance and obesity
Antuna-Puente, B., Fève, B., Fellahi, S., & Bastard, J. (2008) · Diabetes & Metabolism · doi:10.1016/j.diabet.2007.09.004 · Cited by 760
International Day for the Evaluation of Abdominal Obesity (IDEA)
Balkau, B., Deanfield, J. E., Després, J., Bassand, J., Fox, K. A. A., Smith, S. C., Barter, P. J., Tan, C. T., Gaal, L. V., Wïttchen, H., et al. (2007) · Circulation · doi:10.1161/circulationaha.106.676379 · Cited by 755
Adipocytokines and the Metabolic Complications of Obesity
Rasouli, N., & Kern, P. A. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1613 · Cited by 751
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Cipolla‐Neto, J., do Amaral, F. G., Afeche, S. C., Tan, D. X., & Reiter, R. J. (2014) · Journal of Pineal Research · doi:10.1111/jpi.12137 · Cited by 611
García, J. J., López‐Pingarrón, L., Souza, P. A., Tres, A., Escudero, P., García‐Gil, F. A., Tan, D. X., Reiter, R. J., Rodríguez, J. M. ́., & Bernal-Pérez, M. (2014) · Journal of Pineal Research · doi:10.1111/jpi.12128 · Cited by 478
The Effects of Light at Night on Circadian Clocks and Metabolism
Fonken, L. K., & Nelson, R. J. (2014) · Endocrine Reviews · doi:10.1210/er.2013-1051 · Cited by 494
The impact of sleep disorders on glucose metabolism: endocrine and molecular mechanisms
Briançon‐Marjollet, A., Weiszenstein, M., Henri, M., Thomas, A., Godin‐Ribuot, D., & Polak, J. (2015) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-015-0018-3 · Cited by 338
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Xu, P., Wang, J., Hong, F., Wang, S., Jin, X., Xue, T., Jia, L., & Zhai, Y. (2017) · Journal of Pineal Research · doi:10.1111/jpi.12399 · Cited by 281
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Nie, Q., Chen, H., Hu, J., Fan, S., & Nie, S. (2018) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2018.1536646 · Cited by 207
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Rubio-Sastre, P., Scheer, F. A. J. L., Gómez-Abellán, P., Madrid, J. A., & Garaulet, M. (2014) · SLEEP · doi:10.5665/sleep.4088 · Cited by 180
Endocrine Effects of Circadian Disruption
Bedrosian, T. A., Fonken, L. K., & Nelson, R. J. (2016) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021115-105102 · Cited by 170
Agil, A., Reiter, R. J., Jiménez‐Aranda, A., Arias, R. I., Navarro‐Alarcón, M., Marchal, J. A., Adem, A., & Fernández‐Vázquez, G. (2012) · Journal of Pineal Research · doi:10.1111/jpi.12012 · Cited by 161
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Sharma, S., Singh, H., Ahmad, N., Mishra, P., & Tiwari, A. (2015) · Archives of Endocrinology and Metabolism · doi:10.1590/2359-3997000000098 · Cited by 135
Szewczyk‐Golec, K., Woźniak, A., & Reiter, R. J. (2015) · Journal of Pineal Research · doi:10.1111/jpi.12257 · Cited by 153
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Hinshaw, L., Dalla Man, C., Nandy, D. K., Saad, A., Bharucha, A. E., Levine, J. A., Rizza, R. A., Basu, R., Carter, R. E., Cobelli, C., et al. (2013) · Diabetes · doi:10.2337/db12-1759 · Cited by 125
The role of melatonin, a multitasking molecule, in retarding the processes of ageing
Majidinia, M., Reiter, R. J., Shakouri, S. K., & Yousefi, B. (2018) · Ageing Research Reviews · doi:10.1016/j.arr.2018.07.010 · Cited by 126
Nduhirabandi, F., Toit, E. F. D., & Lochner, A. (2012) · Acta Physiologica · doi:10.1111/j.1748-1716.2012.02410.x · Cited by 116
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Ding, S. Z., Lin, N., Sheng, X., Zhao, Y., Su, Y., Xu, L., Tong, R., Yang, Y., Fu, Y., He, J., et al. (2019) · Journal of Pineal Research · doi:10.1111/jpi.12581 · Cited by 113
Jiang, T., Chang, Q., Cai, J., Fan, J., Zhang, X., & Xu, G. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/3528274 · Cited by 111
Melatonin and the pathologies of weakened or dysregulated circadian oscillators
Hardeland, R. (2016) · Journal of Pineal Research · doi:10.1111/jpi.12377 · Cited by 112
Vázquez, G. F., Reiter, R. J., & Agil, A. (2018) · Journal of Pineal Research · doi:10.1111/jpi.12472 · Cited by 108
Self-citationAmin, A. H., El-Missiry, M. A., & Othman, A. I. (2014) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2014.12.002 · Cited by 93
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Speksnijder, E. M., Bisschop, P. H. L. T., Siegelaar, S. E., Stenvers, D. J., & Kalsbeek, A. (2024) · Journal of Pineal Research · doi:10.1111/jpi.12956 · Cited by 100
Sun, H., Wang, X., Chen, J., Song, K., Gusdon, A. M., Li, L., Bu, L., & Qu, S. (2016) · Lipids in Health and Disease · doi:10.1186/s12944-016-0370-9 · Cited by 89
Melatonin alters the glycolytic profile of Sertoli cells: implications for male fertility
Rocha, C. S. F., Martins, A. D., Rato, L., Silva, B. M., Oliveira, P. F., & Alves, M. G. (2014) · Molecular Human Reproduction · doi:10.1093/molehr/gau080 · Cited by 88
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Agil, A., El‐Hammadi, M. M., Jiménez‐Aranda, A., Tassi, M., Abdo, W. S., Fernández‐Vázquez, G., & Reiter, R. J. (2015) · Journal of Pineal Research · doi:10.1111/jpi.12241 · Cited by 87
Self-citationThe role of melatonin in the treatment of type 2 diabetes mellitus and Alzheimer's disease
Shen, S., Liao, Q., Wong, Y. K., Chen, X., Yang, C., Xu, C., Sun, J., & Wang, J. (2022) · International Journal of Biological Sciences · doi:10.7150/ijbs.66871 · Cited by 91
Melatonin and metabolic regulation: a review
Navarro‐Alarcón, M., Ruiz‐Ojeda, F. J., Blanca-Herrera, R. M., A‐Serrano, M. M., Acuña-Castroviejo, D., Fernández‐Vázquez, G., & Agil, A. (2014) · Food & Function · doi:10.1039/c4fo00317a · Cited by 77
Self-citationOu, J., Huang, J., Zhao, D., Du, B., & Wang, M. (2018) · Food & Function · doi:10.1039/c7fo01508a · Cited by 72
Ebaid, H., Bashandy, S. A. E., Abdel-Mageed, A. M., Al‐Tamimi, J., Hassan, I., & Alhazza, I. M. (2020) · Nutrition & Metabolism · doi:10.1186/s12986-019-0419-7 · Cited by 72
RetractedAbdulwahab, D. A., El-Missiry, M. A., Shabana, S. M., Othman, A. I., & Amer, M. E. (2021) · Heliyon · doi:10.1016/j.heliyon.2021.e06474 · Cited by 70
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Ishihara, A., Courville, A. B., & Chen, K. Y. (2023) · Nutrients · doi:10.3390/nu15061391 · Cited by 69
Inubushi, T., Kamemura, N., Oda, M., Sakùrai, J., Nakaya, Y., Harada, N., Suenaga, M., Matsunaga, Y., Ishidoh, K., & Katunuma, N. (2012) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.58.415 · Cited by 65
Metwally, M. M. M., Ebraheim, L. L. M., & Galal, A. A. A. (2018) · Acta Histochemica · doi:10.1016/j.acthis.2018.09.008 · Cited by 64
Salido, E. M., Bordone, M., Laurentiis, A. D., Chianelli, M. S., Sarmiento, M. I. K., Dorfman, D., & Rosenstein, R. E. (2012) · Journal of Pineal Research · doi:10.1111/jpi.12008 · Cited by 62
Circadian rhythms, insulin action, and glucose homeostasis
Tan, E., & SCOTT, E. M. (2014) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0000000000000061 · Cited by 58
Diabetes mellitus and melatonin: Where are we?
Patel, R., PARMAR, N. R., Palit, S. P., RATHWA, N. N., Ramachandran, A. V., & Begum, R. (2022) · Biochimie · doi:10.1016/j.biochi.2022.01.001 · Cited by 58
Gonciarz, M., Bielański, W., Partyka, R., Brzozowski, T., Konturek, P. C., Eszyk, J., Celiński, K., Reiter, R. J., & Konturek, S. J. (2013) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2012.01023.x · Cited by 56
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Sudar-Milovanovic, E. M., Gluvic, Z. M., Obradovic, M. M., Zarić, B. L., & Isenović, E. R. (2021) · Current Medicinal Chemistry · doi:10.2174/0929867328666210714153649 · Cited by 57
Neuroimmune endocrine effects of antidepressants
Carvalho, L. A. (2012) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s16409 · Cited by 52
Merlin, J., Evans, B. A., Dehvari, N., Sato, M., Bengtsson, T., & Hutchinson, D. S. (2015) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201500251 · Cited by 56
Brown adipose tissue and novel therapeutic approaches to treat metabolic disorders
Román, S., Agil, A., Perán, M., Alvaro-Galue, E., Ruiz‐Ojeda, F. J., Fernández‐Vázquez, G., & Marchal, J. A. (2014) · Translational research · doi:10.1016/j.trsl.2014.11.002 · Cited by 54
Self-citationFarid, A., Moussa, P., Youssef, M., Haytham, M., Shamy, A., & Safwat, G. (2022) · Saudi Journal of Biological Sciences · doi:10.1016/j.sjbs.2022.103313 · Cited by 51
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Kim, Y., Nam, K. I., & Song, J. (2018) · Frontiers in Neurology · doi:10.3389/fneur.2018.00867 · Cited by 54
Winiarska, K., Dzik, J. M., Labudda, M., Focht, D., Sierakowski, B., Owczarek, A., Komorowski, L., & Bielecki, W. (2015) · Journal of Pineal Research · doi:10.1111/jpi.12296 · Cited by 50
Nduhirabandi, F., Huisamen, B., Strijdom, H., Blackhurst, D., & Lochner, A. (2014) · Journal of Pineal Research · doi:10.1111/jpi.12171 · Cited by 48
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Wang, S., Zhai, X., Li, S., McCabe, M. F., Wang, X., & Rong, P. (2015) · PLoS ONE · doi:10.1371/journal.pone.0124195 · Cited by 47
Chen, L., He, X., Zhang, Y., Chen, X., Lai, X., Shao, J., Shi, Y., & Zhou, N. (2014) · Biochemistry · doi:10.1021/bi500092e · Cited by 46
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Li, S., Zhai, X., Rong, P., McCabe, M. F., Wang, X., Zhao, J., Ben, H., & Wang, S. (2014) · PLoS ONE · doi:10.1371/journal.pone.0112066 · Cited by 44
Molina-Carballo, A., Naranjo-Gómez, A., Uberos, J., Justicia-Martínez, F., Ruiz-Ramos, M.-J., Cubero-Millán, I., Contreras-Chova, F., Augustin-Morales, M.-D.-C., Khaldy-Belkadi, H., & Muñoz-Hoyos, A. (2013) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2012.09.020 · Cited by 43
Huang, J., Wang, X., Tao, G., Song, Y., Ho, C., Zheng, J., & Ou, S. (2018) · Food & Function · doi:10.1039/c7fo01825h · Cited by 43
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Self-citationAmeliorative effects of topical ramelteon on imiquimod-induced psoriasiform inflammation in mice
Khafaji, A. W. M., Al-Zubaidy, A. A., Farhood, I. G., & Salman, H. (2024) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-024-03017-7 · Cited by 36
Winiarska, K., Focht, D., Sierakowski, B., Lewandowski, K., ORLOWSKA, M., & Usarek, M. (2014) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2014.04.005 · Cited by 36
Lo, C., Lin, S., Chang, J., & Chien, Y. (2017) · Nutrients · doi:10.3390/nu9111187 · Cited by 36
Nishiyama, K., & Hirai, K. (2014) · PLoS ONE · doi:10.1371/journal.pone.0102073 · Cited by 36
Allagui, M. S., Feriani, A., Bouoni, Z., Alimi, H., Murat, J., & Feki, A. E. (2014) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-014-0340-5 · Cited by 34
Sleep Control, GPCRs, and Glucose Metabolism
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Effect of bedtime melatonin consumption on diabetes control and lipid profile
Rezvanfar, M. R., Heshmati, G., Chehrei, A., Haghverdi, F., Rafiee, F., & Rezvanfar, F. (2016) · International Journal of Diabetes in Developing Countries · doi:10.1007/s13410-016-0497-2 · Cited by 33
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Mok, J. X., Ooi, J. H., Ng, K. Y., Koh, R. Y., & Chye, S. M. (2019) · Hormone Molecular Biology and Clinical Investigation · doi:10.1515/hmbci-2019-0036 · Cited by 35
Farhadi, N., Ghareghani, M., & Farhadi, Z. (2016) · Biomedical Journal · doi:10.1016/j.bj.2015.09.003 · Cited by 33
Therapeutic potential of melatonin as a chronobiotic and cytoprotective agent in diabetes mellitus
Wajid, F., Poolacherla, R., Mim, F. K., Bangash, A., & Rutkofsky, I. H. (2020) · Journal of Diabetes & Metabolic Disorders · doi:10.1007/s40200-020-00585-2 · Cited by 33
Maher, A. M., Saleh, S. R., Elguindy, N., Hashem, H. M., & Yacout, G. (2020) · Life Science · doi:10.1016/j.lfs.2020.117427 · Cited by 30
Navarro‐Alarcón, M., Ruiz‐Ojeda, F. J., Blanca-Herrera, R. M., & Agil, A. (2013) · Nutrition · doi:10.1016/j.nut.2012.11.005 · Cited by 29
Self-citationWang, L., McFadden, J. W., Yang, G., Zhu, H., Lian, H., Fu, T., Sun, Y., Gao, T., & Li, M. (2021) · Journal of Animal Physiology and Animal Nutrition · doi:10.1111/jpn.13497 · Cited by 28
Melatonin Improves Endoplasmic Reticulum Stress-Mediated IRE1α Pathway in Zücker Diabetic Fatty Rat
Aouichat, S., Navarro‐Alarcón, M., Alarcón‐Guijo, P., Salagre, D., Ncir, M., Zourgui, L., & Agil, A. (2021) · Pharmaceuticals · doi:10.3390/ph14030232 · Cited by 27
Self-citationAgil, A., Elmahallawy, E. K., Rodríguez-Ferrer, J. M., Adem, A., Bastaki, S. M. A., Alabbadi, I., Solano, Y. A. F., & Navarro‐Alarcón, M. (2015) · Food & Function · doi:10.1039/c5fo00590f · Cited by 28
Self-citationLi, Q., Zheng, T., Chen, J., Li, B., Zhang, Q., Yang, S., Shao, J., Guan, W., & Zhang, S. (2024) · Journal of Advanced Research · doi:10.1016/j.jare.2024.04.025 · Cited by 30
Dim light at night: physiological effects and ecological consequences for infectious disease
Kernbach, M. E., Hall, R. J., Burkett-Cadena, N. D., Unnasch, T. R., & Martin, L. B. (2018) · Integrative and Comparative Biology · doi:10.1093/icb/icy080 · Cited by 28
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Porfirio, M. C., de Almeida, J.-P. G., Stornelli, M., Giovinazzo, S., Purper‐Ouakil, D., & Masi, G. (2017) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s127564 · Cited by 26
Tavares, B. S., Tsosura, T. V. S., Mattera, M. S. D. L. C., Santelli, J. O., Belardi, B. E., Chiba, F. Y., Cintra, L. T. Â., da Silva, C. C., & Matsushita, D. H. (2021) · International Endodontic Journal · doi:10.1111/iej.13474 · Cited by 26
Lu, Z., Li, Y., Brinson, C. W., Kirkwood, K. L., Lopes-Virella, M. F., & Huang, Y. Q. (2016) · Oral Diseases · doi:10.1111/odi.12596 · Cited by 27
Zhou, J., Zhang, J., Luo, X., Li, M., Yue, Y., Laudon, M., Jia, Z., & Zhang, R. (2017) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2017.07.001 · Cited by 26
Kubota, M., Watanabe, R., Yamaguchi, M., Hosojima, M., Saito, A., Fujii, M., Fujimura, S., & Kadowaki, M. (2016) · British Journal Of Nutrition · doi:10.1017/s0007114516003512 · Cited by 25
Gonzaga, N. A., Awata, W. M. C., Ficher, S. P., Assis, V. O., Alves, J. V., Tostes, R. C., & Tirapelli, C. R. (2020) · Journal of Pineal Research · doi:10.1111/jpi.12710 · Cited by 25
She, M., Hou, H., Wang, Z., Zhang, C., Laudon, M., & Yin, W. (2014) · Biochimie · doi:10.1016/j.biochi.2014.05.001 · Cited by 25
Zhai, X., Sun, C., Rong, P., Li, S., McCabe, M. F., Wang, X., Mao, J., & Wang, S. (2015) · Journal of Pain · doi:10.1016/j.jpain.2015.12.003 · Cited by 24
Tsunoda, T., Yamada, M., Akiyama, T., Minami, T., Yoshii, T., Kondo, Y., Satoh, S., & Terauchi, Y. (2016) · Journal of Clinical Medicine Research · doi:10.14740/jocmr2754w · Cited by 24
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Metadata
- Authors
- Agil, A., Rosado, I., Ruiz, R., Figueroa, A., Zen, N., & Fernández‐Vázquez, G.
- Affiliations
- Universidad de Granada (ES)
- Carlos III Hospital (ES)
- Corresponding author
- Agil, Ahmad
- ORCID
- Agil, Ahmad
- Venue
- Journal of Pineal Research
- Publisher
- Wiley
- Published
- 2011-08-25
- Volume
- 52
- Issue
- 2
- Pages
- 203-210
- ISSN
- 0742-3098 (ISSN-L)
- 1600-079X
- OpenAlex
- W1793372331
- Cited by
- 169
- References
- 71
- Citations by year
- 2026: 3 · 2025: 6 · 2024: 12 · 2023: 5 · 2022: 6 · 2021: 18 · 2020: 11 · 2019: 9 · 2018: 15 · 2017: 12 · 2016: 13 · 2015: 16 · 2014: 21 · 2013: 14 · 2012: 8
- FWCI
- 6.35
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Pineal Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- European Commission
- Universidad de Granada
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Pancreatic function and diabetes
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Keywords
- melatonin, glucose homeostasis, Zucker diabetic fatty rats, type 2 diabetes, insulin resistance, beta-cell function, hyperleptinemia, adiponectin, free fatty acids, fasting hyperglycemia, metabolic syndrome, obesity, young adults
- MeSH terms
- Animals, Antioxidants, Diabetes Mellitus, Type 2, Disease Models, Animal, Fatty Acids, Nonesterified, Glucose, Homeostasis, Hyperglycemia, Insulin, Male, Melatonin, Rats, Zucker, Metabolic Syndrome, Rats
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