Pineal Melatonin: Cell Biology of Its Synthesis and of Its Physiological Interactions*

The Circadian Rhythm of Plasma Melatonin During the Normal Menstrual Cycle and in Amenorrheic Women*

BRZEZINSKI, A., LYNCH, H. J., SEIBEL, M. M., DENG, M. H., NADER, T. M., & WURTMAN, R. J. (1988) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-66-5-891 · Cited by 177 · see citing works

Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life

Bäckhed, F., Roswall, J., Peng, Y., Feng, Q., Jia, H., Kovatcheva-Datchary, P., Li, Y., Xia, Y., Xie, H., Zhong, H., et al. (2015) · Cell Host & Microbe · doi:10.1016/j.chom.2015.04.004 · Cited by 3,315 · see citing works

Action Spectrum for Melatonin Regulation in Humans: Evidence for a Novel Circadian Photoreceptor

Brainard, G. C., Hanifin, J. P., Greeson, J. M., Byrne, B., Glickman, G., Gerner, E., & Rollag, M. D. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-16-06405.2001 · Cited by 1,930 · see citing works

One molecule, many derivatives: A never-ending interaction of melatonin with reactive oxygen and nitrogen species?

Tan, D., Manchester, L. C., Terron, M. P., Flores, L. J., & Reiter, R. J. (2007) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2006.00407.x · Cited by 1,601 · see citing works

Melatonin—A pleiotropic, orchestrating regulator molecule

Hardeland, R., Cardinali, D. P., Srinivasan, V., Spence, D. W., Brown, G. M., & Pandi-Perumal, S. R. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2010.12.004 · Cited by 843 · see citing works

Neuropathogenesis of Delirium: Review of Current Etiologic Theories and Common Pathways

Maldonado, J. R. (2013) · The American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2013.09.005 · Cited by 745 · see citing works

Untitled work

Slominski (2012) · doi:10.1007/978-3-642-19683-6_1 · Cited by 461 · see citing works

The cutaneous serotoninergic/melatoninergic system: securing a place under the sun

Slominski, A., Wortsman, J., & Tobin, D. J. (2005) · The FASEB Journal · doi:10.1096/fj.04-2079rev · Cited by 402 · see citing works

Melatonin: A Mitochondrial Targeting Molecule Involving Mitochondrial Protection and Dynamics

Tan, D.-X., Manchester, L., Qin, L., & Reiter, R. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17122124 · Cited by 402 · see citing works

Melatonin and stable circadian rhythms optimize maternal, placental and fetal physiology

Reiter, R. J., Tan, D. X., Korkmaz, A., & Rosales-Corral, S. A. (2014) · Human Reproduction Update · doi:10.1093/humupd/dmt054 · Cited by 371 · see citing works

Melatonin: A Pleiotropic Molecule Regulating Inflammation

Radogna, F., Diederich, M., & Ghibelli, L. (2010) · Biochemical Pharmacology · doi:10.1016/j.bcp.2010.07.041 · Cited by 342 · see citing works

Melatonin: Action as antioxidant and potential applications in human disease and aging

Bonnefont-Rousselot, D., & Collin, F. (2010) · Toxicology · doi:10.1016/j.tox.2010.04.008 · Cited by 320 · see citing works

Circadian mechanisms of 24-hour blood pressure regulation and patterning

Smolensky, M. H., Hermida, R. C., & Portaluppi, F. (2017) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2016.02.003 · Cited by 237 · see citing works

Estrogen, cognition and female ageing

Genazzani, A. R., Pluchino, N., Luisi, S., & Luisi, M. (2007) · Human Reproduction Update · doi:10.1093/humupd/dml042 · Cited by 237 · see citing works

Melatonin as an anti-inflammatory agent modulating inflammasome activation

Favero, G., Franceschetti, L., Bonomini, F., Rodella, L. F., & Rezzani, R. (2017) · International Journal of Endocrinology · doi:10.1155/2017/1835195 · Cited by 233 · see citing works

Pineal Calcification, Melatonin Production, Aging, Associated Health Consequences and Rejuvenation of the Pineal Gland

Tan, D., Xu, B., Zhou, X., & Reiter, R. (2018) · Molecules · doi:10.3390/molecules23020301 · Cited by 220 · see citing works

Molecular links between endocrine, nervous and immune system during chronic stress

Zefferino, R., Di Gioia, S., & Conese, M. (2021) · Brain and Behavior · doi:10.1002/brb3.1960 · Cited by 204 · see citing works

Beneficial pleiotropic actions of melatonin in an experimental model of septic shock in mice: regulation of pro‐/anti‐inflammatory cytokine network, protection against oxidative damage and anti‐apoptotic effects

Carrillo‐Vico, A., Lardone, P. J., Naji, L., Fernández‐Santos, J. M., Martín‐Lacave, I., Guerrero, J. M., & Calvo, J. R. (2005) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2005.00265.x · Cited by 204 · see citing works

Individual and synergistic antioxidative actions of melatonin: studies with vitamin E, vitamin C, glutathione and desferrrioxamine (desferoxamine) in rat liver homogenates

Gitto, E., Tan, D.-X., Reiter, R. J., Karbownik, M., Manchester, L. C., Cuzzocrea, S., Fulia, F., & Barberi, I. (2001) · Journal of Pharmacy and Pharmacology · doi:10.1211/0022357011777747 · Cited by 196 · see citing works

Fundamental issues related to the origin of melatonin and melatonin isomers during evolution: relation to their biological functions.

Tan, D.-X., Zheng, X., Kong, J., Manchester, L., Hardeland, R., Kim, S., Xu, X., & Reiter, R. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms150915858 · Cited by 188 · see citing works

Melatonin improves glucose homeostasis in young Zucker diabetic fatty rats

Agil, A., Rosado, I., Ruiz, R., Figueroa, A., Zen, N., & Fernández‐Vázquez, G. (2012) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2011.00928.x · Cited by 169 · see citing works

Melatonin reverses H ₂ O ₂ ‐induced premature senescence in mesenchymal stem cells via the <scp>SIRT</scp> 1‐dependent pathway

Zhou, L., Chen, X., Liu, T., Gong, Y., Chen, S., Pan, G., Cui, W., Luo, Z., Pei, M., Yang, H., et al. (2015) · Journal of Pineal Research · doi:10.1111/jpi.12250 · Cited by 158 · see citing works

Mitochondria: the birth place, battle ground and the site of melatonin metabolism in cells

Tan, D.-X., & Reiter, R. J. (2019) · Melatonin Research · doi:10.32794/mr11250011 · Cited by 172 · see citing works

Dipper and Non-Dipper Blood Pressure 24-Hour Patterns: Circadian Rhythm–Dependent Physiologic and Pathophysiologic Mechanisms

Fabbian, F., Smolensky, M. H., Tiseo, R., Pala, M., Manfredini, R., & Portaluppi, F. (2013) · Chronobiology International · doi:10.3109/07420528.2012.715872 · Cited by 147 · see citing works

Cellular Mechanisms of Melatonin: Insight from Neurodegenerative Diseases

Chen, D., Zhang, T., & Lee, T. H. (2020) · Biomolecules · doi:10.3390/biom10081158 · Cited by 140 · see citing works

Melatonin Treatment Improves Mesenchymal Stem Cells Therapy by Preserving Stemness during Long-term <i>In Vitro</i> Expansion

Shuai, Y., Liao, L., Su, X., Yu, Y., Shao, B., Jing, H., Zhang, X., Deng, Z., & Jin, Y. (2016) · Theranostics · doi:10.7150/thno.15412 · Cited by 137 · see citing works

The role of melatonin in diabetes: therapeutic implications

Sharma, S., Singh, H., Ahmad, N., Mishra, P., & Tiwari, A. (2015) · Archives of Endocrinology and Metabolism · doi:10.1590/2359-3997000000098 · Cited by 135 · see citing works

Pharmacological utility of melatonin in the treatment of septic shock: experimental and clinical evidence

Escames, G., Acuña-Castroviejo, D., López, L. C., Tan, D.-X., Maldonado, M. D., Sánchez-Hidalgo, M., León, J., & Reiter, R. J. (2006) · Journal of Pharmacy and Pharmacology · doi:10.1211/jpp.58.9.0001 · Cited by 118 · see citing works

Melatonin and its metabolites ameliorate ultraviolet B‐induced damage in human epidermal keratinocytes

Janjetovic, Z., Nahmias, Z. P., Hanna, S., Jarrett, S. G., Kim, T., Reiter, R. J., & Slominski, A. T. (2014) · Journal of Pineal Research · doi:10.1111/jpi.12146 · Cited by 113 · see citing works

Melatonin reduces intramuscular fat deposition by promoting lipolysis and increasing mitochondrial function

Liu, K., Yu, W., Wei, W., Zhang, X., Tian, Y., Sherif, M., Liu, X., Dong, C., Wu, W., Zhang, L., et al. (2019) · Journal of Lipid Research · doi:10.1194/jlr.m087619 · Cited by 74 · see citing works

Myeloperoxidase-catalyzed oxidation of melatonin by activated neutrophils

de Oliveira Silva, S., Ximenes, V. F., Catalani, L. H., & Campa, A. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.3993 · Cited by 72 · see citing works

Depressed nocturnal plasma melatonin levels in drug-free paranoid schizophrenics

Monteleone, P., Maj, M., Fusco, M., Kemali, D., & Reiter, R. J. (1992) · Schizophrenia Research · doi:10.1016/0920-9964(92)90077-i · Cited by 71 · see citing works

Melatonin and Its Metabolites Ameliorate UVR-Induced Mitochondrial Oxidative Stress in Human MNT-1 Melanoma Cells

Kleszczyński, K., Bilska, B., Stegemann, A., Flis, D. J., Ziolkowski, W., Pyza, E., Luger, T. A., Reiter, R. J., Böhm, M., & Slominski, A. T. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19123786 · Cited by 54 · see citing works

Effects of moonlight exposure on plasma melatonin rhythms in the seagrass rabbitfish, Siganus canaliculatus

Rahman, M. S., Kim, B.-H., Takemura, A., Park, C.-B., & Lee, Y.-D. (2004) · Journal of Biological Rhythms · doi:10.1177/0748730404266712 · Cited by 50 · see citing works

Impact of Time-Restricted Feeding and Dawn-to-Sunset Fasting on Circadian Rhythm, Obesity, Metabolic Syndrome, and Nonalcoholic Fatty Liver Disease

Mindikoglu, A. L., Opekun, A. R., Gagan, S. K., & Devaraj, S. (2017) · Gastroenterology Research and Practice · doi:10.1155/2017/3932491 · Cited by 49 · see citing works

Abnormal circadian rhythm of melatonin in Smith–Magenis syndrome patients with <i>RAI1</i> point mutations

Boone, P. M., Reiter, R. J., Glaze, D. G., Tan, D., Lupski, J. R., & Potocki, L. (2011) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.34098 · Cited by 47 · see citing works

Impact of UVA exposure on psychological parameters and circulating serotonin and melatonin

Gambichler, T., Bader, A., Vojvodic, M., Bechara, F. G., Sauermann, K., Altmeyer, P., & Hoffmann, K. (2002) · BMC Dermatology · doi:10.1186/1471-5945-2-6 · Cited by 44 · see citing works

Melatonin attenuates the sympathetic nerve responses to orthostatic stress in humans

Ray, C. A. (2003) · The Journal of Physiology · doi:10.1111/j.1469-7793.2003.01043.x · Cited by 51 · see citing works

Therapeutic potential of melatonin in colorectal cancer: Focus on lipid metabolism and gut microbiota

Pan, S., Guo, Y., Hong, F., Xu, P., & Zhai, Y. (2022) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2021.166281 · Cited by 37 · see citing works

Melatonin ameliorates the drug induced nephrotoxicity: Molecular insights

Raza, Z., & Naureen, Z. (2020) · Nefrología · doi:10.1016/j.nefro.2019.06.009 · Cited by 43 · see citing works

Cloning and expression of melatonin receptors in the mudskipper Boleophthalmus pectinirostris: their role in synchronizing its semilunar spawning rhythm

Hong, L. Y., Hong, W. S., Zhu, W. B., Shi, Q., You, X. X., & Chen, S. X. (2014) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2013.11.004 · Cited by 34 · see citing works

Apoptosis in primary lymphoid organs with aging

Sainz, R. M., Mayo, J. C., Reiter, R. J., Tan, D. X., & Rodriguez, C. (2003) · Microscopy Research and Technique · doi:10.1002/jemt.10414 · Cited by 32 · see citing works

Changes in nocturnal pineal melatonin synthesis during the perimenopausal period: Relation to estrogen levels in female rats

Okatani, Y., Morioka, N., & Hayashi, K. (1999) · Journal of Pineal Research · doi:10.1111/j.1600-079x.1999.tb00598.x · Cited by 30 · see citing works

Influence of light-dark and lunar cycles on the ocular melatonin rhythms in the seagrass rabbitfish, a lunar-synchronized spawner

Rahman, M. S., Kim, B., Takemura, A., Park, C., & Lee, Y. (2004) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2004.00147.x · Cited by 25 · see citing works

Melatonin potentiates NE-induced vasoconstriction without augmenting cytosolic calcium concentration

Vandeputte, C., Giummelly, P., Atkinson, J., Delagrange, P., Scalbert, E., & Capdeville-Atkinson, C. (2001) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.2001.280.1.h420 · Cited by 20 · see citing works

Comparisons Between Successful Versus Unsuccessful Switches From Benzodiazepines or Zolpidem (Z-Drug) to Controlled-Release Melatonin in Patients With Major Depressive Disorder and Insomnia

An, J. H., Park, M. J., Fava, M., Mischoulon, D., Kim, H., Jang, J., Hong, J. P., Park, J. S., & Jeon, H. J. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00444 · Cited by 7 · see citing works

Melatoninergic System in the Skin

Slominski, A. T., Zmijewski, M. A., Skobowiat, C., Zbytek, B., Slominski, R. M., & Steketee, J. D. (2012) · Advances in Anatomy, Embryology and Cell Biology · doi:10.1007/978-3-642-19683-6_3 · Cited by 4 · see citing works

The effect of sleep restriction and psychological load on the diurnal metabolic changes in tryptamine-related compounds in human urine

Minami, M., Takahashi, H., Sasaki, T., Matsumoto, S., Sakai, K., Inagaki, H., Yamano, Y., & Miyake, H. (2012) · Environmental Health and Preventive Medicine · doi:10.1007/s12199-011-0222-1 · Cited by 3 · see citing works