Cited by 170Probiotics and Fermented FoodsExercise and Physiological ResponsesGastrointestinal motility and disorders

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The Effect of Probiotics on Respiratory Infections and Gastrointestinal Symptoms during Training in Marathon Runners

Kekkonen, Riina A., Vasankari, Tommi J., Vuorimaa, Timo, Haahtela, Tari, Julkunen, Ilkka, Korpela, Riitta·2007·International Journal of Sport Nutrition and Exercise Metabolism

DOI 10.1123/ijsnem.17.4.352

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Abstract

Heavy exercise is associated with an increased risk of upper respiratory tract infections. Strenuous exercise also causes gastrointestinal (GI) symptoms. In previous studies probiotics have reduced respiratory tract infections and GI symptoms in general populations including children, adults, and the elderly. These questions have not been studied in athletes before. The purpose of this study was to investigate the effect of probiotics on the number of healthy days, respiratory infections, and GI-symptom episodes in marathon runners in the summer. Marathon runners ( N = 141) were recruited for a randomized, double-blind intervention study during which they received Lactobacillus rhamnosus GG (LGG) or placebo for a 3-mo training period. At the end of the training period the subjects took part in a marathon race, after which they were followed up for 2 wk. The mean number of healthy days was 79.0 in the LGG group and 73.4 in the placebo group ( P = 0.82). There were no differences in the number of respiratory infections or GI-symptom episodes. The duration of GI-symptom episodes in the LGG group was 2.9 vs. 4.3 d in the placebo group during the training period ( P = 0.35) and 1.0 vs. 2.3 d, respectively, during the 2 wk after the marathon ( P = 0.046). LGG had no effect on the incidence of respiratory infections or GI-symptom episodes in marathon runners, but it seemed to shorten the duration of GI-symptom episodes.

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Authors: Kekkonen, R. A., Vasankari, T. J., Vuorimaa, T., Haahtela, T., Julkunen, I., & Korpela, R.
Affiliations: University of Helsinki (FI)
ORCID: Vasankari, Tommi J.
Haahtela, Tari
Julkunen, Ilkka
Korpela, Riitta
Venue: International Journal of Sport Nutrition and Exercise Metabolism
Publisher: Human Kinetics
Published: 2007-08
Volume: 17
Issue: 4
Pages: 352-363
ISSN: 1526-484X (ISSN-L)
1543-2742
DOI: 10.1123/ijsnem.17.4.352
OpenAlex: W2160362327
Cited by: 170
References: 44
Citations by year: 2026: 3 · 2025: 9 · 2024: 4 · 2023: 4 · 2022: 21 · 2021: 11 · 2020: 9 · 2019: 19 · 2018: 12 · 2017: 2 · 2016: 11 · 2015: 14 · 2014: 5 · 2013: 12 · 2012: 11
FWCI: 8.66
Type: journal article
Language: en
Open access: closed
Locations: International Journal of Sport Nutrition and Exercise Metabolism (publishedVersion)
PubMed (publishedVersion)
Funders: Valio
Topics: Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Health Sciences › Medicine › Physiology (medical) › Exercise and Physiological Responses
Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Keywords: probiotics, Lactobacillus rhamnosus GG, marathon runners, upper respiratory tract infection, gastrointestinal symptoms, athletes, endurance training
MeSH terms: Adult, Aged, Double-Blind Method, Female, Humans, Male, Middle Aged, Physical Endurance, Respiratory Tract Infections, Risk Factors, Running, Treatment Outcome, Probiotics, Lacticaseibacillus rhamnosus

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The Effect of Probiotics on Respiratory Infections and Gastrointestinal Symptoms during Training in Marathon Runners

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