The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Cyclooxygenase Isozymes: The Biology of Prostaglandin Synthesis and Inhibition
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Cyclooxygenases: Structural, cellular, and molecular biology
Smith, W. L., DeWitt, D. L., & Garavito, R. M. (2000) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.69.1.145 · Cited by 2,925
McGeer, P. L., Schulzer, M., & McGeer, E. G. (1996) · Neurology · doi:10.1212/wnl.47.2.425 · Cited by 1,367
Risk of Alzheimer's disease and duration of NSAID use
Stewart, W. F., Kawas, C., Corrada, M., & Metter, E. J. (1997) · Neurology · doi:10.1212/wnl.48.3.626 · Cited by 1,132
FLOWER, R. J., & VANE, J. R. (1972) · Nature · doi:10.1038/240410a0 · Cited by 779
Impaired febrile response in mice lacking the prostaglandin E receptor subtype EP3
Ushikubi, F., Segi, E., Sugimoto, Y., Murata, T., Matsuoka, T., Kobayashi, T., Hizaki, H., Tuboi, K., Katsuyama, M., Ichikawa, A., et al. (1998) · Nature · doi:10.1038/26233 · Cited by 677 · cited 9×
“Although COX-2 is primarily involved in the fever response to LPS, source components of this response are dependent on COX-1 (Zhang et al., 2003) E. Immune System Mouse macrophages stimulated with inflammatory mediators to induce COX-2 release PGE2 and PGI2, whereas stimulated human monocytes and macrophages secrete l…”
BackgroundInfluentialFailure of Parturition in Mice Lacking the Prostaglandin F Receptor
Sugimoto, Y., Yamasaki, A., Segi, E., Tsuboi, K., Aze, Y., Nishimura, T., Oida, H., Yoshida, N., Tanaka, T., Katsuyama, M., et al. (1997) · Science · doi:10.1126/science.277.5326.681 · Cited by 608 · cited 1×
“The action of PGF2 on the FP receptor of the corpus luteum induces luteolysis, which terminates progesterone production, and hence triggers parturition, for, in the absence of progesterone, the uterus becomes more sensitive to oxytocin (Sugimoto et al., 1997).”
BackgroundKozak, K. R., Crews, B. C., Morrow, J. D., Wang, L.-H., Ma, Y. H., Weinander, R., Jakobsson, P.-J., & Marnett, L. J. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m206788200 · Cited by 368
Cao, C., Matsumura, K., Yamagata, K., & Watanabe, Y. (1996) · Brain Research · doi:10.1016/0006-8993(96)00575-6 · Cited by 308
Li, S., Wang, Y., Matsumura, K., Ballou, L. R., Morham, S. G., & Blatteis, C. M. (1999) · Brain Research · doi:10.1016/s0006-8993(99)01225-1 · Cited by 270
Langenbach, R., Loftin, C., Lee, C., & Tiano, H. (1999) · Biochemical Pharmacology · doi:10.1016/s0006-2952(99)00158-6 · Cited by 230 · cited 4×
“In addition, in carcinogen-induced tumor initiation and promotion model in skin papilloma formation also exhibited similar requirement for both COX-1 and -2 gene expression (Langenbach et al., 1999b).”
BackgroundInfluential
Cited by
In situ click chemistry generation of cyclooxygenase-2 inhibitors
Bhardwaj, A., Kaur, J., Wuest, M., & Wuest, F. (2017) · Nature Communications · doi:10.1038/s41467-016-0009-6 · Cited by 7,448
Therapeutic potential of resveratrol: the in vivo evidence
Baur, J. A., & Sinclair, D. A. (2006) · Nature Reviews Drug Discovery · doi:10.1038/nrd2060 · Cited by 3,958
Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases
Bhattacharyya, A., Chattopadhyay, R., Mitra, S., & Crowe, S. E. (2014) · Physiological Reviews · doi:10.1152/physrev.00040.2012 · Cited by 2,484
Small-Molecule Two-Photon Probes for Bioimaging Applications
Kim, H. M., & Cho, B. R. (2015) · Chemical Reviews · doi:10.1021/cr5004425 · Cited by 1,047
Endocannabinoid Hydrolysis Generates Brain Prostaglandins That Promote Neuroinflammation
Nomura, D. K., Morrison, B. E., Blankman, J. L., Long, J. Z., Kinsey, S. G., Marcondes, M. C. G., Ward, A. M., Hahn, Y. K., Lichtman, A. H., Conti, B., et al. (2011) · Science · doi:10.1126/science.1209200 · Cited by 727
Adibhatla, R. M., & Hatcher, J. F. (2010) · Antioxidants & Redox Signaling · doi:10.1089/ars.2009.2668 · Cited by 480
Högestätt, E. D., Jönsson, B. A. G., Ermund, A., Andersson, D. A., Björk, H., Alexander, J. P., Cravatt, B. F., Basbaum, A. I., & Zygmunt, P. M. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m501489200 · Cited by 454
Carvacrol, a component of thyme oil, activates PPARα and γ and suppresses COX-2 expression
Hotta, M., Nakata, R., Katsukawa, M., Hori, K., Takahashi, S., & Inoue, H. (2010) · Journal of Lipid Research · doi:10.1194/jlr.m900255-jlr200 · Cited by 260
Acetaminophen and the Cyclooxygenase-3 Puzzle: Sorting out Facts, Fictions, and Uncertainties
Kis, B., Snipes, J. A., & Busija, D. W. (2005) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.105.085431 · Cited by 250
Significance of brain tissue oxygenation and the arachidonic acid cascade in stroke
Rink, C., & Khanna, S. (2011) · Antioxidants & Redox Signaling · doi:10.1089/ars.2010.3474 · Cited by 233
Role of cytochrome P450 enzymes in the bioactivation of polyunsaturated fatty acids
Konkel, A., & Schunck, W.-H. (2011) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2010.09.009 · Cited by 227
Cyclooxygenase-2 in synaptic signaling
Yang, H., & Chen, C. (2008) · Current Pharmaceutical Design · doi:10.2174/138161208784480144 · Cited by 195
Pillaiyar, T., Meenakshisundaram, S., Manickam, M., & Sankaranarayanan, M. (2020) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2020.112275 · Cited by 140
Medeiros, R., Figueiredo, C. P., Pandolfo, P., Duarte, F. S., Prediger, R. D. S., Passos, G. F., & Calixto, J. B. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.01.040 · Cited by 121
Citral, a component of lemongrass oil, activates PPARα and γ and suppresses COX-2 expression
Katsukawa, M., Nakata, R., Takizawa, Y., Hori, K., Takahashi, S., & Inoue, H. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2010.07.004 · Cited by 120
Müller-Decker, K. (2011) · Cancer and Metastasis Reviews · doi:10.1007/s10555-011-9306-z · Cited by 73
Synthesis and biological evaluation of some hydrazone derivatives as anti-inflammatory agents
Asim Kaplancikli, Z., Dilek Altintop, M., Ozdemir, A., Turan-Zitouni, G., I. Khan, S., & Tabanca, N. (2012) · Letters in Drug Design & Discovery · doi:10.2174/157018012799129828 · Cited by 68
Using anesthetics and analgesics in experimental traumatic brain injury
Rowe, R. K., Harrison, J. L., Thomas, T. C., Pauly, J. R., Adelson, P. D., & Lifshitz, J. (2013) · Lab Animal · doi:10.1038/laban.257 · Cited by 58
Pentón-Rol, G., Marín-Prida, J., & Falcón-Cama, V. (2018) · Behavioral Sciences · doi:10.3390/bs8010015 · Cited by 50
Grim, T. W., Ghosh, S., Hsu, K.-L., Cravatt, B. F., Kinsey, S. G., & Lichtman, A. H. (2014) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2014.07.008 · Cited by 50
(2017) · Europe PMC (PubMed Central) · Cited by 44
Ruiz-Saenz, A., Atreya, C. E., Wang, C., Pan, B., Dreyer, C. A., Brunen, D., Prahallad, A., Muñoz, D. P., Ramms, D. J., Burghi, V., et al. (2023) · Nature Cancer · doi:10.1038/s43018-022-00508-5 · Cited by 39
Pharmacological hypotheses: Is acetaminophen selective in its cyclooxygenase inhibition?
Esh, C. J., Chrismas, B. C. R., Mauger, A. R., & Taylor, L. (2021) · Pharmacology Research & Perspectives · doi:10.1002/prp2.835 · Cited by 38
Interaction mechanisms between major depressive disorder and non-alcoholic fatty liver disease
Shao, Q., Wu, Y., Ji, J., Xu, T., Yu, Q., Ma, C., Liao, X., Cheng, F., & Wang, X. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.711835 · Cited by 32
Nam, S. M., Kim, J. W., Yoo, D. Y., Choi, J. H., Kim, W., Jung, H. Y., Won, M.-H., Hwang, I. K., Seong, J. K., & Yoon, Y. S. (2013) · Neurochemical Research · doi:10.1007/s11064-013-1169-y · Cited by 26
Ayoub, S. S., & Flower, R. J. (2019) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2019.172609 · Cited by 19
Ayoub, S. S., Wood, E. G., Hassan, S.-U., & Bolton, C. (2011) · Inflammation Research · doi:10.1007/s00011-011-0352-3 · Cited by 19
Honda, K. (2011) · Journal of Oral Science · doi:10.2334/josnusd.53.87 · Cited by 15
Acetaminophen (Paracetamol) Induces Hypothermia During Acute Cold Stress
Foster, J., Mauger, A. R., Govus, A., Hewson, D., & Taylor, L. (2017) · Clinical Drug Investigation · doi:10.1007/s40261-017-0560-x · Cited by 13
Reinauer, C., Censarek, P., Kaber, G., Weber, A.-A., Steger, G., Klamp, T., & Schrör, K. (2013) · bchm · doi:10.1515/hsz-2012-0309 · Cited by 7
Metadata
- Authors
- Simmons, D. L., Botting, R. M., & Hla, T.
- Venue
- Pharmacological Reviews
- Publisher
- Elsevier BV
- Published
- 2004-09
- Volume
- 56
- Issue
- 3
- Pages
- 387-437
- ISSN
- 0031-6997 (ISSN-L)
- OpenAlex
- W2158960911
- Cited by
- 1,693
- References
- 14
- FWCI
- 43.80
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
