Mediators of Chronic Obstructive Pulmonary Disease

α1-Antitrypsin polymerization and the serpinopathies: pathobiology and prospects for therapy

Lomas, D. A., & Mahadeva, R. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0216782 · Cited by 215

Mechanism of cigarette smoke condensate-induced acute inflammatory response in human bronchial epithelial cells

Hellermann, G. R., Nagy, S. B., Kong, X., Lockey, R. F., & Mohapatra, S. S. (2002) · Respiratory Research · doi:10.1186/rr172 · Cited by 212

Urban air pollution and chronic obstructive pulmonary disease: a review

Sunyer, J. (2001) · European Respiratory Journal · doi:10.1183/09031936.01.17510240 · Cited by 212

Erythromycin Inhibits Respiratory Glycoconjugate Secretion from Human Airways In Vitro

Goswami, S. K., Kivity, S., & Marom, Z. (1990) · American Review of Respiratory Disease · doi:10.1164/ajrccm/141.1.72 · Cited by 212

Increased Nitrosothiols in Exhaled Breath Condensate in Inflammatory Airway Diseases

CORRADI, M., MONTUSCHI, P., DONNELLY, L. E., PESCI, A., KHARITONOV, S. A., & BARNES, P. J. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.163.4.2001108 · Cited by 210

A selective inhibitor of inducible nitric oxide synthase inhibits exhaled breath nitric oxide in healthy volunteers and asthmatics

Hansel, T. T., Kharitonov, S. A., Donnelly, L. E., Erin, E. M., Currie, M. G., Moore, W. M., Manning, P. T., Recker, D. P., & Barnes, P. J. (2003) · The FASEB Journal · doi:10.1096/fj.02-0633fje · Cited by 208

Elevated substance P content in induced sputum from patients with asthma and patients with chronic bronchitis.

Tomaki, M., Ichinose, M., Miura, M., Hirayama, Y., Yamauchi, H., Nakajima, N., & Shirato, K. (1995) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.151.3.7533601 · Cited by 205

Exacerbations of Bronchitis: Bronchial Eosinophilia and Gene Expression for Interleukin-4, Interleukin-5, and Eosinophil Chemoattractants

ZHU, J., QIU, Y. S., MAJUMDAR, S., GAMBLE, E., MATIN, D., TURATO, G., FABBRI, L. M., BARNES, N., SAETTA, M., & JEFFERY, P. K. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.164.1.2007050 · Cited by 203

Myeloperoxidase produces nitrating oxidants in vivo

Gaut, J. P., Byun, J., Tran, H. D., Lauber, W. M., Carroll, J. A., Hotchkiss, R. S., Belaaouaj, A., & Heinecke, J. W. (2002) · Journal of Clinical Investigation · doi:10.1172/jci15021 · Cited by 202

Increased Leukotrienes in Exhaled Breath Condensate in Childhood Asthma

Csoma, Z., Kharitonov, S. A., Balint, B., Bush, A., Wilson, N. M., & Barnes, P. J. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200203-233oc · Cited by 199

Enhanced Expression of Vascular Endothelial Growth Factor in Pulmonary Arteries of Smokers and Patients with Moderate Chronic Obstructive Pulmonary Disease

Santos, S., Peinado, V. I., Ramírez, J., Morales-Blanhir, J., Bastos, R., Roca, J., Rodriguez-Roisin, R., & Barberà, J. A. (2003) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200210-1233oc · Cited by 199

Lung mucosal immunity: immunoglobulin-A revisited

Pilette, C., Ouadrhiri, Y., Godding, V., Vaerman, J.-P., & Sibille, Y. (2001) · European Respiratory Journal · doi:10.1183/09031936.01.00228801 · Cited by 199

Analysis of Expired Air for Oxidation Products

Paredi, P., Kharitonov, S. A., & Barnes, P. J. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.2206012 · Cited by 197

Accumulation of Langerhans' Cells on the Epithelial Surface of the Lower Respiratory Tract in Normal Subjects in Association with Cigarette Smoking

Casolaro, M. A., Bernaudin, J.-F., Saltini, C., Ferrans, V. J., & Crystal, R. G. (1988) · American Review of Respiratory Disease · doi:10.1164/ajrccm/137.2.406 · Cited by 196

EFFECTS OF STIMULUS AND CELL TYPE ON THE EXPRESSION OF THE −308 TUMOUR NECROSIS FACTOR PROMOTER POLYMORPHISM

Kroeger, K. M., Steer, J. H., Joyce, D. A., & Abraham, L. J. (2000) · Cytokine · doi:10.1006/cyto.1999.0529 · Cited by 195

Sputum and plasma endothelin-1 levels in exacerbations of chronic obstructive pulmonary disease

Roland, M. (2001) · Thorax · doi:10.1136/thorax.56.1.30 · Cited by 194

Immune response in asymptomatic smokers

Zeidel, A., Beilin, B., Yardeni, I., Mayburd, E., Smirnov, G., & Bessler, H. (2002) · Acta Anaesthesiologica Scandinavica · doi:10.1034/j.1399-6576.2002.460806.x · Cited by 193

Cathepsin B, L, and S Cleave and Inactivate Secretory Leucoprotease Inhibitor

Taggart, C. C., Lowe, G. J., Greene, C. M., Mulgrew, A. T., O'Neill, S. J., Levine, R. L., & McElvaney, N. G. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m103220200 · Cited by 193

Bioactive Proteinase 3 on the Cell Surface of Human Neutrophils: Quantification, Catalytic Activity, and Susceptibility to Inhibition

Campbell, E. J., Campbell, M. A., & Owen, C. A. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.165.6.3366 · Cited by 191

Do GOLD stages of COPD severity really correspond to differences in health status?

Antonelli-Incalzi, R., Imperiale, C., Bellia, V., Catalano, F., Scichilone, N., Pistelli, R., Rengo, F., & the SaRA investigators (2003) · European Respiratory Journal · doi:10.1183/09031936.03.00101203 · Cited by 190

Structure-Function Relationship between the Human Chemokine Receptor CXCR3 and Its Ligands

Clark-Lewis, I., Mattioli, I., Gong, J.-H., & Loetscher, P. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m209470200 · Cited by 189

Analysis of exhaled breath condensate for monitoring airway inflammation

Montuschi, P., & Barnes, P. J. (2002) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(02)02020-5 · Cited by 187

Anti-neutrophil elastase defense of the normal human respiratory epithelial surface provided by the secretory leukoprotease inhibitor.

Vogelmeier, C., Hubbard, R. C., Fells, G. A., Schnebli, H. P., Thompson, R. C., Fritz, H., & Crystal, R. G. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115021 · Cited by 187

THE ISOPROSTANES: THEIR QUANTIFICATION AS AN INDEX OF OXIDANT STRESS STATUS IN VIVO†

MORROW, J. D. (2000) · Drug Metabolism Reviews · doi:10.1081/dmr-100102340 · Cited by 187

Secretory leukocyte protease inhibitor suppresses the production of monocyte prostaglandin H synthase-2, prostaglandin E2, and matrix metalloproteinases.

Zhang, Y., DeWitt, D. L., McNeely, T. B., Wahl, S. M., & Wahl, L. M. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119254 · Cited by 185

Redox-dependent Regulation of Nuclear Import of the Glucocorticoid Receptor

Okamoto, K., Tanaka, H., Ogawa, H., Makino, Y., Eguchi, H., Hayashi, S.-I., Yoshikawa, N., Poellinger, L., Umesono, K., & Makino, I. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.15.10363 · Cited by 184

Immunolocalization of elastase in human emphysematous lungs.

Damiano, V. V., Tsang, A., Kucich, U., Abrams, W. R., Rosenbloom, J., Kimbel, P., Fallahnejad, M., & Weinbaum, G. (1986) · Journal of Clinical Investigation · doi:10.1172/jci112600 · Cited by 183

Sputum matrix metalloproteinase-9, tissue inhibitor of metalloprotinease-1, and their molar ratio in patients with chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis and healthy subjects

BEEH, K. M., BEIER, J., KORNMANN, O., & BUHL, R. (2003) · Respiratory Medicine · doi:10.1053/rmed.2003.1493 · Cited by 182

TGFβ1 allele association with asthma severity

Pulleyn, L. J., Newton, R., Adcock, I. M., & Barnes, P. J. (2001) · Human Genetics · doi:10.1007/s00439-001-0617-y · Cited by 178

Exhaled Carbon Monoxide and Nitric Oxide in COPD

Montuschi, P., Kharitonov, S. A., & Barnes, P. J. (2001) · Chest · doi:10.1378/chest.120.2.496 · Cited by 178

Severity of Elastase-Induced Emphysema Is Decreased in Tumor Necrosis Factor-α and Interleukin-1β Receptor-Deficient Mice

Lucey, E. C., Keane, J., Kuang, P.-P., Snider, G. L., & Goldstein, R. H. (2002) · Laboratory Investigation · doi:10.1038/labinvest.3780397 · Cited by 176

Increased content of thiobarbituric acid-reactive substances and hydrogen peroxide in the expired breath condensate of patients with stable chronic obstructive pulmonary disease: no significant effect of cigarette smoking

NOWAK, D., KASIELSKI, M., ANTCZAK, A., PIETRAS, T., & BIALASIEWICZ, P. (1999) · Respiratory Medicine · doi:10.1053/rmed.1999.0574 · Cited by 175

Fully human anti-interleukin-8 monoclonal antibodies: potential therapeutics for the treatment of inflammatory disease states

Yang, X.-D., Corvalan, J. R. F., Wang, P., Roy, C. M.-N., & Davis, C. G. (1999) · Journal of Leukocyte Biology · doi:10.1002/jlb.66.3.401 · Cited by 174

Cigarette Smoking-induced Changes in the Number and Differentiated State of Pulmonary Dendritic Cells/ Langerhans Cells

Soler, P., Moreau, A., Basset, F., & Hance, A. J. (1989) · American Review of Respiratory Disease · doi:10.1164/ajrccm/139.5.1112 · Cited by 173

Upregulation of Two Death Pathways of Perforin/Granzyme and FasL/Fas in Septic Acute Respiratory Distress Syndrome

HASHIMOTO, S., KOBAYASHI, A., KOOGUCHI, K., KITAMURA, Y., ONODERA, H., & NAKAJIMA, H. (2000) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.161.1.9810007 · Cited by 173

lnterleukin-8 in Airway Inflammation in Patients with Asthma and Chronic Obstructive Pulmonary Disease

Nocker, R. E. T., Schoonbrood, D. F. M., van de Graaf, E. A., Hack, E., Lutter, R., Jansen, H. M., & Out, T. A. (1996) · International Archives of Allergy and Immunology · doi:10.1159/000237218 · Cited by 171

The cellular composition of induced sputum in chronic obstructive pulmonary disease

Peleman, R. A., Rytilä, P. H., Kips, J. C., Joos, G. F., & Pauwels, R. A. (1999) · European Respiratory Journal · doi:10.1034/j.1399-3003.1999.13d24.x · Cited by 170

Specific CXC but not CC chemokines cause elevated monocyte migration in COPD: a role for CXCR2

Traves, S. L., Smith, S. J., Barnes, P. J., & Donnelly, L. E. (2004) · Journal of Leukocyte Biology · doi:10.1189/jlb.1003495 · Cited by 169

High levels of interleukin-6 in the exhaled breath condensate of patients with COPD

Bucchioni, E., Kharitonov, S. A., Allegra, L., & Barnes, P. J. (2003) · Respiratory Medicine · doi:10.1016/j.rmed.2003.07.008 · Cited by 168

Increased exhaled nitric oxide in patients with stable chronic obstructive pulmonary disease

Corradi, M., Majori, M., Cacciani, G. C., Consigli, G. F., de'Munari, E., & Pesci, A. (1999) · Thorax · doi:10.1136/thx.54.7.572 · Cited by 167

Leukotriene Receptor Antagonists and Synthesis Inhibitors Reverse Survival in Eosinophils of Asthmatic Individuals

LEE, E., ROBERTSON, T., SMITH, J., & KILFEATHER, S. (2000) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.161.6.9907054 · Cited by 166

Effect of Cigarette Smoke on the Permeability and IL-1 β and sICAM-1 Release from Cultured Human Bronchial Epithelial Cells of Never-Smokers, Smokers, and Patients with Chronic Obstructive Pulmonary Disease

Rusznak, C., Mills, P. R., Devalia, J. L., Sapsford, R. J., Davies, R. J., & Lozewicz, S. (2000) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/ajrcmb.23.4.3959 · Cited by 163

Increased tumour necrosis factor‐α plasma levels during moderate-intensity exercise in COPD patients

Rabinovich, R. A., Figueras, M., Ardite, E., Carbó, N., Troosters, T., Filella, X., Barberà, J. A., Fernandez-Checa, J. C., Argilés, J. M., & Roca, J. (2003) · European Respiratory Journal · doi:10.1183/09031936.03.00042702 · Cited by 162

Human Tc1 and Tc2/Tc0 CD8 T-cell clones display distinct cell surface and functional phenotypes

Vukmanovic-Stejic, M., Vyas, B., Gorak-Stolinska, P., Noble, A., & Kemeny, D. M. (2000) · Blood · doi:10.1182/blood.v95.1.231 · Cited by 161

The role of matrix metalloproteinases (MMPs) in the pathophysiology of chronic obstructive pulmonary disease (COPD): a therapeutic role for inhibitors of MMPs?

Belvisi, M. G., & Bottomley, K. M. (2003) · Inflammation Research · doi:10.1007/s000110300020 · Cited by 160

Increased MCP-1 and MIP-1β in bronchoalveolar lavage fluid of chronic bronchitics

Capelli, A., Stefano, A. D., Gnemmi, I., Balbo, P. E., Cerutti, C. G., Balbi, B., Lusuardi, M., & Donner, C. F. (1999) · European Respiratory Journal · doi:10.1034/j.1399-3003.1999.14a27.x · Cited by 160

Low Grade Rhinovirus Infection Induces a Prolonged Release of IL-8 in Pulmonary Epithelium

Johnston, S. L., Papi, A., Bates, P. J., Mastronarde, J. G., Monick, M. M., & Hunninghake, G. W. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.160.12.6172 · Cited by 159

Secretory Leucoprotease Inhibitor Prevents Lipopolysaccharide-induced IκBα Degradation without Affecting Phosphorylation or Ubiquitination

Taggart, C. C., Greene, C. M., McElvaney, N. G., & O'Neill, S. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m203710200 · Cited by 159

Primary Human Alveolar Type II Epithelial Cell Chemokine Release: Effects of Cigarette Smoke and Neutrophil Elastase

Witherden, I. R., Vanden Bon, E. J., Goldstraw, P., Ratcliffe, C., Pastorino, U., & Tetley, T. D. (2004) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.4890 · Cited by 158

Emphysematous Lung Destruction by Cigarette Smoke

Meshi, B., Vitalis, T. Z., Ionescu, D. N., Elliott, W. M., Liu, C., Wang, X., Hayashi, S., & Hogg, J. C. (2002) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/ajrcmb.26.1.4253 · Cited by 158

Lung mucosal immunity: immunoglobulin‐A revisited

Lusuardi, M., Capelli, A., Stefano, A. D., & Donner, C. F. (2002) · European Respiratory Journal · doi:10.1183/09031936.02.00303902 · Cited by 157

Oxidative Stress in Airways: Is There a Role for Extracellular Superoxide Dismutase?

Bowler, R. P., & Crapo, J. D. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.2206014 · Cited by 157

Increased levels of interleukin-8 in BAL fluid from smokers susceptible to pulmonary emphysema

Tanino, M. A. (2002) · Thorax · doi:10.1136/thorax.57.5.405 · Cited by 156

ROS in the local and systemic pathogenesis of COPD

LANGEN, R. C. J., Korn, S. H., & Wouters, E. F. �. (2003) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(03)00316-2 · Cited by 155

Oxygen metabolites stimulate release of high-molecular-weight glycoconjugates by cell and organ cultures of rodent respiratory epithelium via an arachidonic acid-dependent mechanism.

Adler, K. B., Holden-Stauffer, W. J., & Repine, J. E. (1990) · Journal of Clinical Investigation · doi:10.1172/jci114436 · Cited by 155

Rare diseases bullet 9: Adult pulmonary Langerhans' cell histiocytosis

Tazi, A. (2000) · Thorax · doi:10.1136/thorax.55.5.405 · Cited by 153

Decreased haem oxygenase-1 and increased inducible nitric oxide synthase in the lung of severe COPD patients

Maestrelli, P., Páska, C., Saetta, M. P., Turato, G., Nowicki, Y., Monti, S., Formichi, B. A., Miniati, M., & Fabbri, L. M. (2003) · European Respiratory Journal · doi:10.1183/09031936.03.00098203 · Cited by 150

The role of secretory leukocyte proteinase inhibitor and elafin (elastase-specific inhibitor/skin-derived antileukoprotease) as alarm antiproteinases in inflammatory lung disease

Sallenave, J. (2000) · Respiratory Research · doi:10.1186/rr18 · Cited by 149

Possible effects of vascular endothelial growth factor in the pathogenesis of chronic obstructive pulmonary disease

Kanazawa, H., Asai, K., Hirata, K., & Yoshikawa, J. (2003) · The American Journal of Medicine · doi:10.1016/s0002-9343(02)01562-0 · Cited by 144

New treatments for copd

Barnes, P. J. (2002) · Nature Reviews Drug Discovery · doi:10.1038/nrd820 · Cited by 144

STAT4 activation in smokers and patients with chronic obstructive pulmonary disease

Stefano, A. D., Caramori, G., Capelli, A., Gnemmi, I., Ricciardolo, F. L. M., Oates, T. M., Donner, C. F., Chung, K. F., Barnes, P. J., & Adcock, I. M. (2004) · European Respiratory Journal · doi:10.1183/09031936.04.00080303 · Cited by 144

Transforming growth factor- 1 genotype and susceptibility to chronic obstructive pulmonary disease

Wu, L. (2004) · Thorax · doi:10.1136/thorax.2003.005769 · Cited by 142

Redox and oxidant-mediated regulation of apoptosis signaling pathways: immuno-pharmaco-redox conception of oxidative siege versus cell death commitment

Haddad, J. J. (2004) · International Immunopharmacology · doi:10.1016/j.intimp.2004.02.002 · Cited by 140

Sputum chemotactic activity in chronic obstructive pulmonary disease: effect of alpha1-antitrypsin deficiency and the role of leukotriene B4 and interleukin 8

Woolhouse, I. (2002) · Thorax · doi:10.1136/thorax.57.8.709 · Cited by 140

Pharmacological modulation of interleukin-17-induced GCP-2-, GRO-α- and interleukin-8 release in human bronchial epithelial cells

Prause, O., Laan, M., Lötvall, J. O., & Lindén, A. (2003) · European Journal of Pharmacology · doi:10.1016/s0014-2999(03)01341-4 · Cited by 139

Phagocytosis of Small Carbon Particles (PM10) by Alveolar Macrophages Stimulates the Release of Polymorphonuclear Leukocytes From Bone Marrow

Terashima, T., Wiggs, B., English, D. R., Hogg, J. C., & van Eeden, S. F. (1997) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.155.4.9105091 · Cited by 139

Proteinase 3, a Potent Secretagogue in Airways, Is Present in Cystic Fibrosis Sputum

Witko‐Sarsat, V., Halbwachs‐Mecarelli, L., Schuster, A., Nusbaum, P., Ueki, I. F., Canteloup, S., Lenoir, G., Descamps‐Latscha, B., & Nadel, J. A. (1999) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/ajrcmb.20.4.3371 · Cited by 138

Increased p21CIP1/WAF1 and B Cell Lymphoma Leukemia-xL Expression and Reduced Apoptosis in Alveolar Macrophages from Smokers

Tomita, K., Caramori, G., Lim, S., Ito, K., Hanazawa, T., Oates, T., Chiselita, I., Jazrawi, E., Chung, K. F., Barnes, P. J., et al. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.2104010 · Cited by 137

Antioxidant macromolecules in the epithelial lining fluid of the normal human lower respiratory tract.

Cantin, A. M., Fells, G. A., Hubbard, R. C., & Crystal, R. G. (1990) · Journal of Clinical Investigation · doi:10.1172/jci114798 · Cited by 135

Urinary Desmosine Excretion in Smokers With and Without Rapid Decline of Lung Function: The Normative Aging Study

Gottlieb, D. J., Stone, P. J., Sparrow, D., Gale, M. E., Weiss, S. T., Snider, G. L., & O’Connor, G. T. (1996) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.154.5.8912738 · Cited by 134

8-Epi-PGF2 Alpha, a Novel Noncyclooxygenase-Derived Prostaglandin, Constricts Airways in Vitro

Kawiková, I., Barnes, P. J., Takahashi, T., Tadjkarimi, S., Yacoub, M. H., & Belvisi, M. G. (1996) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.153.2.8564103 · Cited by 133

The effect of oxidative stress on histone acetylation and IL-8 release

Tomita, K., Barnes, P. J., & Adcock, I. M. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(02)03029-2 · Cited by 131

Genetic Polymorphism in Matrix Metalloproteinase-9 and Pulmonary Emphysema

Minematsu, N., Nakamura, H., Tateno, H., Nakajima, T., & Yamaguchi, K. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.5936 · Cited by 131

Regulation of TNF‐α and IFN‐γ induced CXCL10 expression: participation of the airway smooth muscle in the pulmonary inflammatory response in chronic obstructive pulmonary disease

Hardaker, E. L., Bacon, A. M., Carlson, K., Roshak, A., Foley, J. J., Schmidt, D. B., Buckley, P. T., Comegys, M., Panettieri, R. A., Sarau, H. M., et al. (2003) · The FASEB Journal · doi:10.1096/fj.03-0170fje · Cited by 129

Transforming growth factor beta 1 gene expression in human airways.

Aubert, J., Dalal, B. I., Bai, T. R., Roberts, C. R., Hayashi, S., & Hogg, J. C. (1994) · Thorax · doi:10.1136/thx.49.3.225 · Cited by 127

Predominant TH1 cytokine pattern in peripheral blood from subjects with chronic obstructive pulmonary disease

Majori, M., Corradi, M., Caminati, A., et al. (1999) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(99)70471-9 · Cited by 126

Regulation of Chemotactic and Proadhesive Responses to Chemoattractant Receptors by RGS (Regulator of G-protein Signaling) Family Members

Bowman, E. P., Campbell, J. J., Druey, K. M., Scheschonka, A., Kehrl, J. H., & Butcher, E. C. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.43.28040 · Cited by 125

Tissue inhibitor of metalloproteinases-2 gene polymorphisms in chronic obstructive pulmonary disease.

Hirano, K., Sakamoto, T., Uchida, Y., Morishima, Y., Masuyama, K., Ishii, Y., Nomura, A., Ohtsuka, M., & Sekizawa, K. (2001) · European Respiratory Journal · doi:10.1183/09031936.01.00102101 · Cited by 125

Proteolysis of monocyte CD14 by human leukocyte elastase inhibits lipopolysaccharide-mediated cell activation

Le-Barillec, K., Si‐Tahar, M., Balloy, V., & Chignard, M. (1999) · Journal of Clinical Investigation · doi:10.1172/jci5779 · Cited by 124

Regulation of human airway mucins by acrolein and inflammatory mediators

Borchers, M. T., Carty, M. P., & Leikauf, G. D. (1999) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.1999.276.4.l549 · Cited by 124

Airway eosinophilia and expression of interleukin-5 protein in asthma and in exacerbations of chronic bronchitis

Saetta, M. P., Stefano, A. D., Maestrelli, P., Turato, G., Mapp, C., Pieno, M., ZANGUOCHI, G., Prete, G. D., & Fabbri, L. M. (1996) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.1996.tb00606.x · Cited by 123

Markers of nitric oxide metabolism in sputum and exhaled air are not increased in chronic obstructive pulmonary disease

Rutgers, S. R., van der Mark, T. W., Coers, W., Moshage, H. J., Timens, W., Kauffman, H. F., Koëter, G. H., & Postma, D. S. (1999) · Thorax · doi:10.1136/thx.54.7.576 · Cited by 123

Human cathepsin W, a putative cysteine protease predominantly expressed in CD8+ T‐lymphocytes

Linnevers, C. J., Smeekens, S. P., & Brömme, D. (1997) · FEBS Letters · doi:10.1016/s0014-5793(97)00118-x · Cited by 122

Defective Natural Killer and Phagocytic Activities in Chronic Obstructive Pulmonary Disease are Restored by Glycophosphopeptical (Inmunoferón)

I, A. P., Reyes, E., Bernstein, E. D., MARTINEZ, B., Monserrat, J., IZQUIERDO, J. L., Callol, L., de Lucas, P., Álvarez-Sala, R., Álvarez-Sala, J. L., et al. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.163.7.2002015 · Cited by 120

Serial measurements of exhaled nitric oxide during exacerbations of chronic obstructive pulmonary disease

Agustí, A. G. N., Villaverde, J. M. F., & Togores, B. (1999) · European Respiratory Journal · doi:10.1034/j.1399-3003.1999.14c08.x · Cited by 120

Matrix Metalloproteinases Inhibition Attenuates Tobacco Smoke-Induced Emphysema in Guinea Pigs

Selman, M., Cisneros, J., Gaxiola, M., Ramı́rez, R., Kudlacz, E. M., Mitchell, P. G., & Pardo, A. (2003) · CHEST Journal · doi:10.1378/chest.123.5.1633 · Cited by 117

Genetics and respiratory disease bullet 2: Alpha1-antitrypsin deficiency, cirrhosis and emphysema

Mahadeva, R., & Lomas, D. A. (1998) · Thorax · doi:10.1136/thx.53.6.501 · Cited by 117

Effects of interleukin-10 on monocyte/endothelial cell adhesion and MMP-9/TIMP-1 secretion

Mtairag, E. M. (2001) · Cardiovascular Research · doi:10.1016/s0008-6363(00)00287-x · Cited by 117

Lipopolysaccharide-induced NF-κ B Activation and Cytokine Release in Human Alveolar Macrophages Is PKC-independent and TK- and PC-PLC-dependent

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