Mediators of Chronic Obstructive Pulmonary Disease

Immunobiology of Dendritic Cells

Banchereau, J., Briere, F., Caux, C., Davoust, J., Lebecque, S., Liu, Y.-J., Pulendran, B., & Palucka, K. (2000) · Annual Review of Immunology · doi:10.1146/annurev.immunol.18.1.767 · Cited by 6,634

Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly

Beckman, J. S., & Koppenol, W. H. (1996) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1996.271.5.c1424 · Cited by 5,513

Research confuses me: what is the difference between case-control and cohort studies in quantitative research?

Higgins, S. M. F., Macken, A. P., Cullen, W., Saunders, J., Dunne, C. P., & O’Gorman, C. S. (2013) · PubMed · doi:10.34961/9953 · Cited by 4,805

Nuclear Factor-κB — A Pivotal Transcription Factor in Chronic Inflammatory Diseases

Barnes, P. J., & Karin, M. (1997) · New England Journal of Medicine · doi:10.1056/nejm199704103361506 · Cited by 4,669

The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease

Hogg, J. C., Chu, F., Utokaparch, S., Woods, R., Elliott, W. M., Buzatu, L., Cherniack, R. M., Rogers, R. M., Sciurba, F. C., Coxson, H. O., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa032158 · Cited by 3,782

Chronic Obstructive Pulmonary Disease

(2018) · Questions for the Final FFICM Structured Oral Examination · doi:10.1017/9781108233712.025 · Cited by 2,689

The Biology of Chemokines and their Receptors

Rossi, D., & Zlotnik, A. (2000) · Annual Review of Immunology · doi:10.1146/annurev.immunol.18.1.217 · Cited by 2,410

Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis.

Yu, Q., & Stamenkovic, I. (2000) · PubMed · Cited by 1,995

Expression of Endothelin-1 in the Lungs of Patients with Pulmonary Hypertension

Giaid, A., Yanagisawa, M., Langleben, D., Michel, R. P., Levy, R., Shennib, H., Kimura, S., Masaki, T., Duguid, W. P., & Stewart, D. J. (1993) · New England Journal of Medicine · doi:10.1056/nejm199306173282402 · Cited by 1,842

Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-β and promotes tumor invasion and angiogenesis

Yu, Q., & Stamenkovic, I. (2000) · Genes & Development · doi:10.1101/gad.14.2.163 · Cited by 1,754

Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: the ISOLDE trial

Burge, P. S. (2000) · BMJ · doi:10.1136/bmj.320.7245.1297 · Cited by 1,675

The global burden of disease, 1990–2020

Lopez, A. D., & Murray, C. C. J. L. (1998) · Nature Medicine · doi:10.1038/3218 · Cited by 1,614

Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils

Eiserich, J. P., Hristova, M., Cross, C. E., Jones, A. D., Freeman, B. A., Halliwell, B., & van der Vliet, A. (1998) · Nature · doi:10.1038/34923 · Cited by 1,496

A receptor for phosphatidylserine-specific clearance of apoptotic cells

Fadok, V. A., Bratton, D. L., Rose, D. M., Pearson, A., Ezekewitz, R. A. B., & Henson, P. M. (2000) · Nature · doi:10.1038/35011084 · Cited by 1,491

Requirement for Macrophage Elastase for Cigarette Smoke-Induced Emphysema in Mice

Hautamaki, R. D., Kobayashi, D. K., Senior, R. M., & Shapiro, S. D. (1997) · Science · doi:10.1126/science.277.5334.2002 · Cited by 1,469

Chronic obstructive pulmonary disease: molecular and cellularmechanisms

Barnes, P. J., Shapiro, S. D., & Pauwels, R. A. (2003) · European Respiratory Journal · doi:10.1183/09031936.03.00040703 · Cited by 1,439

Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma.

Keatings, V. M., Collins, P. D., Scott, D. M., & Barnes, P. J. (1996) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.153.2.8564092 · Cited by 1,362

Processing of tumour necrosis factor-α precursor by metalloproteinases

Gearing, A. J. H., Beckett, P., Christodoulou, M., Churchill, M., Clements, J., Davidson, A. H., Drummond, A. H., Galloway, W. A., Gilbert, R., Gordon, J. L., et al. (1994) · Nature · doi:10.1038/370555a0 · Cited by 1,194

Oxidants in Cigarette Smoke Radicals, Hydrogen Peroxide, Peroxynitrate, and Peroxynitritea

PRYOR, W. A., & STONE, K. (1993) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1993.tb39148.x · Cited by 1,152

Extracellular matrix remodelling: the role of matrix metalloproteinases

Stamenkovic, I. (2003) · The Journal of Pathology · doi:10.1002/path.1400 · Cited by 1,140

Heme Oxygenase-1: Function, Regulation, and Implication of a Novel Stress-Inducible Protein in Oxidant-Induced Lung Injury

Choi, A. M., & Alam, J. (1996) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/ajrcmb.15.1.8679227 · Cited by 1,126

Inhibition of VEGF receptors causes lung cell apoptosis and emphysema

Kasahara, Y., Tuder, R. M., Taraseviciene-Stewart, L., Le Cras, T. D., Abman, S., Hirth, P. K., Waltenberger, J., & Voelkel, N. F. (2000) · Journal of Clinical Investigation · doi:10.1172/jci10259 · Cited by 1,112

Antioxidant Therapy: A New Pharmacological Approach in Shock, Inflammation, and Ischemia/Reperfusion Injury

Cuzzocrea, S., Riley, D. P., Caputi, A. P., & Salvemini, D. (2001) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01484-4 · Cited by 1,087

Chronic Obstructive Pulmonary Disease

Barnes, P. J. (2000) · New England Journal of Medicine · doi:10.1056/nejm200007273430407 · Cited by 1,078

Long-Term Treatment with Inhaled Budesonide in Persons with Mild Chronic Obstructive Pulmonary Disease Who Continue Smoking

Pauwels, R. A., Löfdahl, C.-G., Laitinen, L. A., Schouten, J. P., Postma, D. S., Pride, N. B., & Ohlsson, S. V. (1999) · New England Journal of Medicine · doi:10.1056/nejm199906243402503 · Cited by 1,074

Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-β1 secretion and the resolution of inflammation

Huynh, M.-L. N., Fadok, V. A., & Henson, P. M. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0211638 · Cited by 957

Reactive oxygen species and cell signaling: Respiratory burst in macrophage signaling

Forman, H. J., & Torres, M. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.2206007 · Cited by 891 · cited 1×

Exhaled Markers of Pulmonary Disease

KHARITONOV, S. A., & BARNES, P. J. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.163.7.2009041 · Cited by 844

Oxidative Stress in Chronic Obstructive Pulmonary Disease

REPINE, J. E., BAST, A., LANKHORST, I., & The Oxidative Stress Study Group (1997) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.156.2.9611013 · Cited by 843

Effect of Inhaled Triamcinolone on the Decline in Pulmonary Function in Chronic Obstructive Pulmonary Disease

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Long-term effect of inhaled budesonide in mild and moderate chronic obstructive pulmonary disease: a randomised controlled trial

Vestbo, J., Søorensen, T., Lange, P., Brix, A., Torre, P., & Viskum, K. (1999) · The Lancet · doi:10.1016/s0140-6736(98)10019-3 · Cited by 816

CD8 + T-Lymphocytes in Peripheral Airways of Smokers with Chronic Obstructive Pulmonary Disease

SAETTA, M., Di STEFANO, A., TURATO, G., FACCHINI, F. M., CORBINO, L., MAPP, C. E., MAESTRELLI, P., CIACCIA, A., & FABBRI, L. M. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.157.3.9709027 · Cited by 792

EMERGING ROLES FOR CYSTEINE PROTEASES IN HUMAN BIOLOGY

Chapman, H. A., Riese, R. J., & Shi, G.-P. (1997) · Annual Review of Physiology · doi:10.1146/annurev.physiol.59.1.63 · Cited by 786

Systemic oxidative stress in asthma, COPD, and smokers

Rahman, I., Morrison, D., Donaldson, K., & MacNee, W. (1996) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.154.4.8887607 · Cited by 774

NEW EMBO MEMBERS' REVIEW: Lysosomal cysteine proteases: facts and opportunities

Turk, V. (2001) · The EMBO Journal · doi:10.1093/emboj/20.17.4629 · Cited by 756

Chemokine receptors: multifaceted therapeutic targets

Proudfoot, A. E. I. (2002) · Nature Reviews Immunology · doi:10.1038/nri722 · Cited by 752

The Plasticity of Dendritic Cell Responses to Pathogens and Their Components

Huang, Q., Liu, D., Majewski, P., Schulte, L. C., Korn, J. M., Young, R. A., Lander, E. S., & Hacohen, N. (2001) · Science · doi:10.1126/science.294.5543.870 · Cited by 748

Relation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations

Bhowmik, A. (2000) · Thorax · doi:10.1136/thorax.55.2.114 · Cited by 730

Glucocorticoid Receptor Recruitment of Histone Deacetylase 2 Inhibits Interleukin-1β-Induced Histone H4 Acetylation on Lysines 8 and 12

Ito, K., Barnes, P. J., & Adcock, I. M. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.18.6891-6903.2000 · Cited by 723

Inflammatory Mediators of Asthma: An Update

Barnes, P. J., Chung, K. F., & Page, C. P. (1998) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01381-4 · Cited by 717

Inflammation in bronchial biopsies of subjects with chronic bronchitis: inverse relationship of CD8+ T lymphocytes with FEV1.

O'Shaughnessy, T. C., Ansari, T. W., Barnes, N. C., & Jeffery, P. K. (1997) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.155.3.9117016 · Cited by 694

Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis

Belaaouaj, A., McCarthy, R., Baumann, M., Gao, Z., Ley, T. J., Abraham, S. N., & Shapiro, S. D. (1998) · Nature Medicine · doi:10.1038/nm0598-615 · Cited by 691

Relationship between bacterial colonisation and the frequency, character, and severity of COPD exacerbations

Patel, I. S. (2002) · Thorax · doi:10.1136/thorax.57.9.759 · Cited by 690

Neutrophil gelatinase B potentiates interleukin-8 tenfold by aminoterminal processing, whereas it degrades CTAP-III, PF-4, and GRO-α and leaves RANTES and MCP-2 intact

Van den Steen, P. E., Proost, P., Wuyts, A., Van Damme, J., & Opdenakker, G. (2000) · Blood · doi:10.1182/blood.v96.8.2673 · Cited by 680

Chemokines and chemokine receptors in leukocyte trafficking

Olson, T. S., & Ley, K. (2002) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00738.2001 · Cited by 674

Recent advances torwards understanding redox mechanisms in the activation of nuclear factor κb

Janssen-Heininger, Y. M. W., Poynter, M. E., & Baeuerle, P. A. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00218-5 · Cited by 666

Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase– and cathepsin-dependent emphysema

Zheng, T., Zhu, Z., Wang, Z., Homer, R. J., Ma, B., Riese, R. J., Chapman, H. A., Shapiro, S. D., & Elias, J. A. (2000) · Journal of Clinical Investigation · doi:10.1172/jci10458 · Cited by 646

Cytokines in asthma

Chung, K. F., & Barnes, P. J. (1999) · Thorax · doi:10.1136/thx.54.9.825 · Cited by 638

Cytokines in chronic obstructive pulmonary disease

Chung, K. F. (2001) · European Respiratory Journal · doi:10.1183/09031936.01.00229701 · Cited by 625

Sputum eosinophilia and short-term response to prednisolone in chronic obstructive pulmonary disease: a randomised controlled trial

Brightling, C. E., Monteiro, W., Ward, R., Parker, D., Morgan, M. D., Wardlaw, A. J., & Pavord, I. D. (2000) · The Lancet · doi:10.1016/s0140-6736(00)02872-5 · Cited by 595

Epidermal growth factor system regulates mucin production in airways

Takeyama, K., Dabbagh, K., Lee, H.-M., Agustí, C., Lausier, J. A., Ueki, I. F., Grattan, K. M., & Nadel, J. A. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.6.3081 · Cited by 579

Anti-TNF-α therapies: the next generation

Palladino, M. A., Bahjat, F. R., Theodorakis, E. A., & Moldawer, L. L. (2003) · Nature Reviews Drug Discovery · doi:10.1038/nrd1175 · Cited by 576

Severity of Airflow Limitation Is Associated with Severity of Airway Inflammation in Smokers

DI STEFANO, A., CAPELLI, A., LUSUARDI, M., BALBO, P., VECCHIO, C., MAESTRELLI, P., MAPP, C. E., FABBRI, L. M., DONNER, C. F., & SAETTA, M. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.158.4.9802078 · Cited by 572

Effects of inhaled and oral glucocorticoids on inflammatory indices in asthma and COPD.

Keatings, V. M., Jatakanon, A., Worsdell, Y. M., & Barnes, P. J. (1997) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.155.2.9032192 · Cited by 558

Oxidative stress and lung inflammation in airways disease

MacNee, W. (2001) · European Journal of Pharmacology · doi:10.1016/s0014-2999(01)01320-6 · Cited by 556

Cellular and Structural Bases of Chronic Obstructive Pulmonary Disease

SAETTA, M., TURATO, G., MAESTRELLI, P., MAPP, C. E., & FABBRI, L. M. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.163.6.2009116 · Cited by 552

Exhaled 8-Isoprostane as an In Vivo Biomarker of Lung Oxidative Stress in Patients with COPD and Healthy Smokers

MONTUSCHI, P., COLLINS, J. V., CIABATTONI, G., LAZZERI, N., CORRADI, M., KHARITONOV, S. A., & BARNES, P. J. (2000) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.162.3.2001063 · Cited by 548

A Second Leukotriene B4 Receptor, Blt2

Yokomizo, T., Kato, K., Terawaki, K., Izumi, T., & Shimizu, T. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.3.421 · Cited by 538

Airway eosinophilia in chronic bronchitis during exacerbations.

Saetta, M., Di Stefano, A., Maestrelli, P., Turato, G., Ruggieri, M. P., Roggeri, A., Calcagni, P., Mapp, C. E., Ciaccia, A., & Fabbri, L. M. (1994) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.150.6.7952628 · Cited by 536

Amplification of Inflammation in Emphysema and Its Association with Latent Adenoviral Infection

RETAMALES, I., ELLIOTT, W. M., MESHI, B., COXSON, H. O., PARE, P. D., SCIURBA, F. C., ROGERS, R. M., HAYASHI, S., & HOGG, J. C. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.164.3.2007149 · Cited by 524

Understanding dendritic cell and T‐lymphocyte traffic through the analysis of chemokine receptor expression

Sallusto, F., & Lanzavecchia, A. (2000) · Immunological Reviews · doi:10.1034/j.1600-065x.2000.17717.x · Cited by 523

Neutrophil Elastase Contributes to Cigarette Smoke-Induced Emphysema in Mice

Shapiro, S. D., Goldstein, N. M., Houghton, A. M., Kobayashi, D. K., Kelley, D., & Belaaouaj, A. (2003) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)63589-4 · Cited by 520

Differences in Airway Inflammation in Patients with Fixed Airflow Obstruction Due to Asthma or Chronic Obstructive Pulmonary Disease

Fabbri, L. M., Romagnoli, M., Corbetta, L., Casoni, G., Busljetic, K., Turato, G., Ligabue, G., Ciaccia, A., Saetta, M., & Papi, A. (2003) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200203-183oc · Cited by 516

Increased Exhalation of Hydrogen Peroxide in Patients With Stable and Unstable Chronic Obstructive Pulmonary Disease

Dekhuijzen, P. N., Aben, K. K., Dekker, I., Aarts, L. P., Wielders, P. L., van Herwaarden, C. L., & Bast, A. (1996) · American journal of respiratory and critical care medicine · doi:10.1164/ajrccm.154.3.8810624 · Cited by 503

Loss of integrin αvβ6-mediated TGF-β activation causes Mmp12-dependent emphysema

Morris, D. G., Huang, X., Kaminski, N., Wang, Y., Shapiro, S. D., Dolganov, G., Glick, A., & Sheppard, D. (2003) · Nature · doi:10.1038/nature01413 · Cited by 500

CD8 + ve Cells in the Lungs of Smokers with Chronic Obstructive Pulmonary Disease

SAETTA, M., BARALDO, S., CORBINO, L., TURATO, G., BRACCIONI, F., REA, F., CAVALLESCO, G., TROPEANO, G., MAPP, C. E., MAESTRELLI, P., et al. (1999) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.160.2.9812020 · Cited by 489

Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line.

Nakamura, H., Yoshimura, K., McElvaney, N. G., & Crystal, R. G. (1992) · Journal of Clinical Investigation · doi:10.1172/jci115738 · Cited by 487

Tumor necrosis factor-alpha levels and weight loss in chronic obstructive pulmonary disease.

Di Francia, M., Barbier, D., Mege, J. L., & Orehek, J. (1994) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.150.5.7952575 · Cited by 485

Alveolar inflammation and its relation to emphysema in smokers.

Finkelstein, R., Fraser, R. S., Ghezzo, H., & Cosio, M. G. (1995) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.152.5.7582312 · Cited by 483

Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages

ITO, K., LIM, S., CARAMORI, G., CHUNG, K. F., BARNES, P. J., & ADCOCK, I. M. (2001) · The FASEB Journal · doi:10.1096/fj.00-0432fje · Cited by 481

Muscle force during an acute exacerbation in hospitalised patients with COPD and its relationship with CXCL8 and IGF-I

Spruit, M. A. (2003) · Thorax · doi:10.1136/thorax.58.9.752 · Cited by 476

Pathophysiological roles of interleukin-8/CXCL8 in pulmonary diseases

Mukaida, N. (2003) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00233.2002 · Cited by 472

Granulocyte Inflammatory Markers and Airway Infection during Acute Exacerbation of Chronic Obstructive Pulmonary Disease

AARON, S. D., ANGEL, J. B., LUNAU, M., WRIGHT, K., FEX, C., LE SAUX, N., & DALES, R. E. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.163.2.2003122 · Cited by 466

Airways obstruction, chronic expectoration, and rapid decline of FEV1 in smokers are associated with increased levels of sputum neutrophils.

Stanescu, D., Sanna, A., Veriter, C., Kostianev, S., Calcagni, P. G., Fabbri, L. M., & Maestrelli, P. (1996) · Thorax · doi:10.1136/thx.51.3.267 · Cited by 462

4-Hydroxy-2-Nonenal, a Specific Lipid Peroxidation Product, Is Elevated in Lungs of Patients with Chronic Obstructive Pulmonary Disease

Rahman, I., van Schadewijk, A. A. M., Crowther, A. J. L., Hiemstra, P. S., Stolk, J., MacNee, W., & De Boer, W. I. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.2110101 · Cited by 460

Release and Activity of Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 by Alveolar Macrophages from Patients with Chronic Obstructive Pulmonary Disease

Russell, R. E. K., Culpitt, S. V., DeMatos, C., Donnelly, L., Smith, M., Wiggins, J., & Barnes, P. J. (2002) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/ajrcmb.26.5.4685 · Cited by 448

Alpha1-Antitrypsin Deficiency — A Model for Conformational Diseases

Carrell, R. W., & Lomas, D. A. (2002) · New England Journal of Medicine · doi:10.1056/nejmra010772 · Cited by 448

Acute Exacerbations of Chronic Obstructive Pulmonary Disease Are Accompanied by Elevations of Plasma Fibrinogen and Serum IL-6 Levels

Seemungal, T., MacCallum, P., Paul, E., Donaldson, G., Bhowmik, A., Jeffries, D., Meade, T., & Wedzicha, J. (2000) · Thrombosis and Haemostasis · doi:10.1055/s-0037-1613998 · Cited by 447

Matrix Metalloproteinase Expression and Production by Alveolar Macrophages in Emphysema

FINLAY, G. A., O'DRISCOLL, L. R., RUSSELL, K. J., D'ARCY, E. M., MASTERSON, J. B., FITZGERALD, M. X., & O'CONNOR, C. M. (1997) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.156.1.9612018 · Cited by 440

Phagocytosing neutrophils produce and release high amounts of the neutrophil-activating peptide 1/interleukin 8.

Bazzoni, F., Cassatella, M. A., Rossi, F., Ceska, M., Dewald, B., & Baggiolini, M. (1991) · The Journal of experimental medicine · doi:10.1084/jem.173.3.771 · Cited by 436

IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes.

Lacraz, S., Nicod, L. P., Chicheportiche, R., Welgus, H. G., & Dayer, J. M. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118286 · Cited by 435

Identification of a Potent, Selective Non-peptide CXCR2 Antagonist That Inhibits Interleukin-8-induced Neutrophil Migration

White, J. R., Lee, J. M., Young, P. R., Hertzberg, R. P., Jurewicz, A. J., Chaikin, M. A., Widdowson, K., Foley, J. J., Martin, L. D., Griswold, D. E., et al. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.17.10095 · Cited by 432

Cigarette smoke induces interleukin-8 release from human bronchial epithelial cells.

Mio, T., Romberger, D. J., Thompson, A. B., Robbins, R. A., Heires, A., & Rennard, S. I. (1997) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.155.5.9154890 · Cited by 430

Increased expression of nuclear factor-κB in bronchial biopsies from smokers and patients with COPD

Di Stefano, A., Caramori, G., Oates, T., Capelli, A., Lusuardi, M., Gnemmi, I., Ioli, F., Chung, K. F., Donner, C. F., Barnes, P. J., et al. (2002) · European Respiratory Journal · doi:10.1183/09031936.02.00272002 · Cited by 429

The dark side of C5a in sepsis

Ward, P. A. (2004) · Nature Reviews Immunology · doi:10.1038/nri1269 · Cited by 422

Oxidants/Antioxidants and COPD

MacNee, W. (2000) · Chest · doi:10.1378/chest.117.5_suppl_1.303s-a · Cited by 421

Effect of High Dose Inhaled Steroid on Cells, Cytokines, and Proteases in Induced Sputum in Chronic Obstructive Pulmonary Disease

CULPITT, S. V., MAZIAK, W., LOUKIDIS, S., NIGHTINGALE, J. A., MATTHEWS, J. L., & BARNES, P. J. (1999) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.160.5.9811058 · Cited by 417

Inflammatory cytokines inhibit myogenic differentiation through activation of nuclear factor‐κΒ

LANGEN, R. C. J., SCHOLS, A. M. W. J., KELDERS, M. C. J. M., WOUTERS, E. F. M., & JANSSEN-HEININGER, Y. M. W. (2001) · The FASEB Journal · doi:10.1096/fj.00-0463 · Cited by 415

Interferon γ Induction of Pulmonary Emphysema in the Adult Murine Lung

Wang, Z., Zheng, T., Zhu, Z., Homer, R. J., Riese, R. J., Chapman, H. A., Shapiro, S. D., & Elias, J. A. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.11.1587 · Cited by 415

SB-505124 Is a Selective Inhibitor of Transforming Growth Factor-β Type I Receptors ALK4, ALK5, and ALK7

DaCosta Byfield, S., Major, C., Laping, N. J., & Roberts, A. B. (2004) · Molecular Pharmacology · doi:10.1124/mol.65.3.744 · Cited by 414

Association between airway bacterial load and markers of airway inflammation in patients with stable chronic bronchitis

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