Variant ribosomal RNA alleles are conserved and exhibit tissue-specific expression

A global reference for human genetic variation

The 1000 Genomes Project Consortium, authors, C., Auton, A., Abecasis, G. R., Steering committee, Altshuler, D. M., Durbin, R. M., Abecasis, G. R., Bentley, D. R., Chakravarti, A., et al. (2015) · Nature · doi:10.1038/nature15393 · Cited by 18,247 · see citing works

A framework for variation discovery and genotyping using next-generation DNA sequencing data

DePristo, M. A., Banks, E., Poplin, R. E., Garimella, K. V., Maguire, J., Hartl, C., Philippakis, A., del Angel, G., Rivas, M. A., Hanna, M., et al. (2011) · Nature Genetics · doi:10.1038/ng.806 · Cited by 11,216 · see citing works

From FastQ data to high confidence variant calls: the Genome Analysis Toolkit best practices pipeline

Van der Auwera, G. A., Carneiro, M. O., Hartl, C., Poplin, R., del Angel, G., Levy‐Moonshine, A., Jordan, T., Shakir, K., Roazen, D., Thibault, J., et al. (2013) · Current Protocols in Bioinformatics · doi:10.1002/0471250953.bi1110s43 · Cited by 6,687 · see citing works

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

Cox, J., Neuhauser, N., Michalski, A., Scheltema, R. A., Olsen, J. V., & Mann, M. (2011) · Journal of Proteome Research · doi:10.1021/pr101065j · Cited by 5,349 · see citing works

Finishing the euchromatic sequence of the human genome

International Human Genome Sequencing Consortium (2004) · Nature · doi:10.1038/nature03001 · Cited by 4,971 · see citing works

Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips

Rappsilber, J., Mann, M., & Ishihama, Y. (2007) · Nature Protocols · doi:10.1038/nprot.2007.261 · Cited by 4,641 · see citing works

Global variation in copy number in the human genome

Redon, R., Ishikawa, S., Fitch, K. R., Feuk, L., Perry, G. H., Andrews, T. D., Fiegler, H., Shapero, M. H., Carson, A. R., Chen, W., et al. (2006) · Nature · doi:10.1038/nature05329 · Cited by 4,276 · see citing works

Molecular mechanisms of mTOR-mediated translational control

Ma, X. M., & Blenis, J. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2672 · Cited by 2,558 · see citing works

Repetitive DNA and next-generation sequencing: computational challenges and solutions

Treangen, T. J., & Salzberg, S. L. (2011) · Nature Reviews Genetics · doi:10.1038/nrg3117 · Cited by 1,710 · see citing works

LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets

Wilm, A., Aw, P. P. K., Bertrand, D., Yeo, G. H. T., Ong, S. H., Wong, C. H., Khor, C. C., Petric, R., Hibberd, M. L., & Nagarajan, N. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks918 · Cited by 1,338 · see citing works

The translational landscape of mTOR signalling steers cancer initiation and metastasis

Hsieh, A. C., Liu, Y., Edlind, M. P., Ingolia, N. T., Janes, M. R., Sher, A., Shi, E. Y., Stumpf, C. R., Christensen, C., Bonham, M. J., et al. (2012) · Nature · doi:10.1038/nature10912 · Cited by 1,313 · see citing works

Summarizing and correcting the GC content bias in high-throughput sequencing

Benjamini, Y., & Speed, T. P. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks001 · Cited by 913 · see citing works

Tuning the ribosome: The influence of rRNA modification on eukaryotic ribosome biogenesis and function

Sloan, K. E., Warda, A. S., Sharma, S., Entian, K.-D., Lafontaine, D. L. J., & Bohnsack, M. T. (2017) · RNA Biology · doi:10.1080/15476286.2016.1259781 · Cited by 707 · see citing works

Specialized ribosomes: a new frontier in gene regulation and organismal biology

Xue, S., & Barna, M. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3359 · Cited by 687 · see citing works

rRNA modifications and ribosome function

Decatur, W. A., & Fournier, M. J. (2002) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(02)02109-6 · Cited by 651 · see citing works

Detecting RNA modifications in the epitranscriptome: predict and validate

Helm, M., & Motorin, Y. (2017) · Nature Reviews Genetics · doi:10.1038/nrg.2016.169 · Cited by 641 · see citing works

Heterogeneous Ribosomes Preferentially Translate Distinct Subpools of mRNAs Genome-wide

Shi, Z., Fujii, K., Kovary, K. M., Genuth, N. R., Röst, H. L., Teruel, M. N., & Barna, M. (2017) · Molecular Cell · doi:10.1016/j.molcel.2017.05.021 · Cited by 638 · see citing works

Structures of the human and Drosophila 80S ribosome

Anger, A. M., Armache, J., Berninghausen, O., Habeck, M., Subklewe, M. S., Wilson, D. N., & Beckmann, R. (2013) · Nature · doi:10.1038/nature12104 · Cited by 629 · see citing works

Ribosome-Mediated Specificity in Hox mRNA Translation and Vertebrate Tissue Patterning

Kondrashov, N., Pusic, A. D., Stumpf, C. R., Shimizu, K., Hsieh, A. C., Xue, S., Ishijima, J., Shiroishi, T., & Barna, M. (2011) · Cell · doi:10.1016/j.cell.2011.03.028 · Cited by 581 · see citing works

Structure of the human 80S ribosome

Khatter, H., Myasnikov, A. G., Natchiar, S. K., & Klaholz, B. P. (2015) · Nature · doi:10.1038/nature14427 · Cited by 546 · see citing works

Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome

Peng, Z., Cheng, Y., Tan, B. C., Kang, L., Tian, Z., Zhu, Y., Zhang, W., Liang, Y., Hu, X., Tan, X., et al. (2012) · Nature Biotechnology · doi:10.1038/nbt.2122 · Cited by 497 · see citing works

One core, two shells: bacterial and eukaryotic ribosomes

Melnikov, S., Ben-Shem, A., Garreau de Loubresse, N., Jenner, L., Yusupova, G., & Yusupov, M. (2012) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2313 · Cited by 477 · see citing works

The correlation between rDNA copy number and genome size in eukaryotes

Prokopowich, C. D., Gregory, T. R., & Crease, T. J. (2003) · Genome · doi:10.1139/g02-103 · Cited by 442 · see citing works

The mammalian ribo-interactome reveals ribosome functional diversity and heterogeneity

Simsek, D., Tiu, G. C., Flynn, R. A., Byeon, G. W., Leppek, K., Xu, A. F., Chang, H. Y., & Barna, M. (2017) · Cell · doi:10.1016/j.cell.2017.05.022 · Cited by 439 · see citing works

Ribosomopathies: There’s strength in numbers

Mills, E. W., & Green, R. (2017) · Science · doi:10.1126/science.aan2755 · Cited by 434 · see citing works

The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription

Santoro, R., Li, J., & Grummt, I. (2002) · Nature Genetics · doi:10.1038/ng1010 · Cited by 406 · see citing works

The Numerous Modified Nucleotides in Eukaryotic Ribosomal RNA

Maden, B. E. H. (1990) · Progress in nucleic acid research and molecular biology · doi:10.1016/s0079-6603(08)60629-7 · Cited by 380 · see citing works

Structures of the Bacterial Ribosome in Classical and Hybrid States of tRNA Binding

Dunkle, J. A., Wang, L., Feldman, M. B., Pulk, A., Chen, V. B., Kapral, G. J., Noeske, J., Richardson, J. S., Blanchard, S. C., & Cate, J. H. D. (2011) · Science · doi:10.1126/science.1202692 · Cited by 373 · see citing works

The Mechanism for Activation of GTP Hydrolysis on the Ribosome

Voorhees, R. M., Schmeing, T. M., Kelley, A. C., & Ramakrishnan, V. (2010) · Science · doi:10.1126/science.1194460 · Cited by 366 · see citing works

Global diversity, population stratification, and selection of human copy-number variation

Sudmant, P. H., Mallick, S., Nelson, B. J., Hormozdiari, F., Krumm, N., Huddleston, J., Coe, B. P., Baker, C., Nordenfelt, S., Bamshad, M., et al. (2015) · Science · doi:10.1126/science.aab3761 · Cited by 345 · see citing works

Genomic architecture and inheritance of human ribosomal RNA gene clustersPreprint

Stults, D. M., Killen, M. W., Pierce, H., & Pierce, A. J. (2007) · Genome Research · doi:10.1101/gr.6858507 · Cited by 316 · see citing works

Structure of mammalian eIF3 in the context of the 43S preinitiation complex

Georges, A. D., Dhote, V., Kühn, L., Hellen, C. U. T., Pestova, T. V., Frank, J., & Hashem, Y. (2015) · Nature · doi:10.1038/nature14891 · Cited by 269 · see citing works

Molecular Mechanisms Mediating Methylation-Dependent Silencing of Ribosomal Gene Transcription

Santoro, R., & Grummt, I. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00317-3 · Cited by 254 · see citing works

Mapping to nucleotide resolution of pseudouridine residues in large subunit ribosomal RNAs from representative eukaryotes, prokaryotes, archaebacteria, mitochondria and chloroplasts

Ofengand, J., & Bakin, A. V. (1997) · Journal of Molecular Biology · doi:10.1006/jmbi.1996.0737 · Cited by 240 · see citing works

Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes

Shao, S., Murray, J., Brown, A., Taunton, J., Ramakrishnan, V., & Hegde, R. S. (2016) · Cell · doi:10.1016/j.cell.2016.10.046 · Cited by 239 · see citing works

Structure and Assembly Pathway of the Ribosome Quality Control Complex

Shao, S., Brown, A., Santhanam, B., & Hegde, R. S. (2015) · Molecular Cell · doi:10.1016/j.molcel.2014.12.015 · Cited by 225 · see citing works

Evolution of the ribosome at atomic resolution

Petrov, A. S., Bernier, C. R., Hsiao, C., Norris, A., Kovacs, N. A., Waterbury, C. C., Stepanov, V. G., Harvey, S. C., Fox, G. E., Wartell, R. M., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1407205111 · Cited by 216 · see citing works

Structural Snapshots of Actively Translating Human Ribosomes

Behrmann, E., Loerke, J., Budkevich, T. V., Yamamoto, K., Schmidt, A., Penczek, P. A., Vos, M. R. J., Bürger, J., Mielke, T., Scheerer, P., et al. (2015) · Cell · doi:10.1016/j.cell.2015.03.052 · Cited by 206 · see citing works

Translating the genome in time and space: Specialized ribosomes, RNA regulons, and RNA-binding proteins

Shi, Z., & Barna, M. (2015) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-100814-125346 · Cited by 205 · see citing works

Analysis of translation using polysome profiling

Chassé, H., Boulben, S., Costache, V., Cormier, P., & Morales, J. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw907 · Cited by 202 · see citing works

Concerted copy number variation balances ribosomal DNA dosage in human and mouse genomes

Gibbons, J. G., Branco, A. T., Godinho, S. A., Yu, S., & Lemos, B. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1416878112 · Cited by 198 · see citing works

Human RPS19, the gene mutated in Diamond-Blackfan anemia, encodes a ribosomal protein required for the maturation of 40S ribosomal subunits

Flygare, J., Aspesi, A., Bailey, J. C., Miyake, K., Caffrey, J. M., Karlsson, S., & Ellis, S. R. (2006) · Blood · doi:10.1182/blood-2006-07-038232 · Cited by 194 · see citing works

Differential Stoichiometry among Core Ribosomal Proteins

Slavov, N., Semrau, S., Airoldi, E. M., Budnik, B., & van Oudenaarden, A. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.09.056 · Cited by 188 · see citing works

Ribosomal deficiencies in Diamond-Blackfan anemia impair translation of transcripts essential for differentiation of murine and human erythroblasts

Horos, R., IJspeert, H., Pospı́šilová, D., Sendtner, R., Andrieu‐Soler, C., Taskesen, E., Nieradka, A., Čmejla, R., Sendtner, M., Touw, I. P., et al. (2011) · Blood · doi:10.1182/blood-2011-06-358200 · Cited by 186 · see citing works

The initiation of mammalian protein synthesis and mRNA scanning mechanism

Lomakin, I. B., & Steitz, T. A. (2013) · Nature · doi:10.1038/nature12355 · Cited by 181 · see citing works

Structure of the no-go mRNA decay complex Dom34–Hbs1 bound to a stalled 80S ribosome

Becker, T. A., Armache, J., Jarasch, A., Anger, A. M., Villa, E., Sieber, H., Motaal, B. A., Mielke, T., Berninghausen, O., & Beckmann, R. (2011) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2057 · Cited by 173 · see citing works

Genome measures used for quality control are dependent on gene function and ancestry

Wang, J., Raskin, L., Samuels, D. C., Shyr, Y., & Guo, Y. (2015) · Bioinformatics · doi:10.1093/bioinformatics/btu668 · Cited by 173 · see citing works

Human rRNA Gene Clusters Are Recombinational Hotspots in Cancer

Stults, D. M., Killen, M. W., Williamson, E. P., Hourigan, J. S., Vargas, H. D., Arnold, S. M., Moscow, J. A., & Pierce, A. J. (2009) · Cancer Research · doi:10.1158/0008-5472.can-09-2680 · Cited by 168 · see citing works

Integrative genomic analysis of human ribosomal DNA

Zentner, G. E., Saiakhova, A., Manaenkov, P., Adams, M. D., & Scacheri, P. C. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkq1326 · Cited by 165 · see citing works

Ribosomal DNA copy number is coupled with gene expression variation and mitochondrial abundance in humans

Gibbons, J. G., Branco, A. T., Yu, S., & Lemos, B. (2014) · Nature Communications · doi:10.1038/ncomms5850 · Cited by 165 · see citing works

Ribosomal DNA copy number loss and sequence variation in cancer

Xu, B., Li, H., Perry, J. M., Singh, V. P., Unruh, J. R., Yu, Z., Zakari, M., McDowell, W., Li, L., & Gerton, J. L. (2017) · PLoS Genetics · doi:10.1371/journal.pgen.1006771 · Cited by 154 · see citing works

Human ribosomal RNA gene arrays display a broad range of palindromic structures

Caburet, S., Conti, C., Schurra, C., Lebofsky, R., Edelstein, S. J., & Bensimon, A. (2005) · Genome Research · doi:10.1101/gr.3970105 · Cited by 143 · see citing works

Intergenic transcripts originating from a subclass of ribosomal DNA repeats silence ribosomal RNA genes in trans

Santoro, R., Schmitz, K., Sandoval, J., & Grummt, I. (2009) · EMBO Reports · doi:10.1038/embor.2009.254 · Cited by 117 · see citing works

Structure and Dynamics of the Mammalian Ribosomal Pretranslocation Complex

Budkevich, T. V., Giesebrecht, J., Altman, R. B., Munro, J. B., Mielke, T., Nierhaus, K. H., Blanchard, S. C., & Spahn, C. M. T. (2011) · Molecular Cell · doi:10.1016/j.molcel.2011.07.040 · Cited by 115 · see citing works

Mysterious Ribosomopathies

McCann, K. L., & Baserga, S. J. (2013) · Science · doi:10.1126/science.1244156 · Cited by 112 · see citing works

Structure of the pre-60S ribosomal subunit with nuclear export factor Arx1 bound at the exit tunnel

Bradatsch, B., Leidig, C., Granneman, S., Gnädig, M., Tollervey, D. W., Böttcher, B., Beckmann, R., & Hurt, E. (2012) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2438 · Cited by 111 · see citing works

Early-life nutrition modulates the epigenetic state of specific rDNA genetic variants in mice

Holland, M. L., Lowe, R., Caton, P. W., Gemma, C., Carbajosa, G., Danson, A. F., Carpenter, A. A. M., Loche, E., Ozanne, S. E., & Rakyan, V. K. (2016) · Science · doi:10.1126/science.aaf7040 · Cited by 106 · see citing works

Clones of human ribosomal DNA containing the complete 18 S-rRNA and 28 S-rRNA genes. Characterization, a detailed map of the human ribosomal transcription unit and diversity among clones

Maden, B. E. H., Dent, C. L., Farrell, T. E., Garde, J., McCallum, F. S., & Wakeman, J. A. (1987) · Biochemical Journal · doi:10.1042/bj2460519 · Cited by 104 · see citing works

Cryo-EM of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus IRES

Muhs, M., Hilal, T., Mielke, T., Skabkin, M. A., Sanbonmatsu, K. Y., Pestova, T. V., & Spahn, C. M. T. (2015) · Molecular Cell · doi:10.1016/j.molcel.2014.12.016 · Cited by 101 · see citing works

Complete sequence of the 45-kb mouse ribosomal DNA repeat: analysis of the intergenic spacer☆

Grozdanov, P., Georgiev, O., & Karagyozov, L. K. (2003) · Genomics · doi:10.1016/s0888-7543(03)00199-x · Cited by 97 · see citing works

Structural characterization of a eukaryotic chaperone—the ribosome-associated complex

Leidig, C., Bange, G., Kopp, J., Amlacher, S., Aravind, A., Wickles, S., Witte, G., Hurt, E., Beckmann, R., & Sinning, I. (2012) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2447 · Cited by 91 · see citing works

Heterogeneity of the translational machinery: Variations on a common theme

Sauert, M., Temmel, H., & Moll, I. (2014) · Biochimie · doi:10.1016/j.biochi.2014.12.011 · Cited by 87 · see citing works

Functional Dynamics within the Human Ribosome Regulate the Rate of Active Protein Synthesis

Ferguson, A., Wang, L., Altman, R. B., Terry, D. S., Juette, M. F., Burnett, B. J., Alejo, J. L. P., Dass, R. A., Parks, M., Vincent, C. T., et al. (2015) · Molecular Cell · doi:10.1016/j.molcel.2015.09.013 · Cited by 84 · see citing works

Localization of nucleolin binding sites on human and mouse pre-ribosomal RNA

Serin, G., Joseph, G., Faucher, C., Ghisolfi, L., Bouche, G., Amalric, F., & Bouvet, P. (1996) · Biochimie · doi:10.1016/0300-9084(96)84759-6 · Cited by 81 · see citing works

The Mouse Genomes Project: a repository of inbred laboratory mouse strain genomes

Adams, D., Doran, A., Lilue, J., & Keane, T. (2015) · Mammalian Genome · doi:10.1007/s00335-015-9579-6 · Cited by 78 · see citing works

Structure of the mammalian ribosomal pre-termination complex associated with eRF1•eRF3•GDPNP

Georges, A. D., Hashem, Y., Unbehaun, A., Grassucci, R. A., Taylor, D. J., Hellen, C. U. T., Pestova, T. V., & Frank, J. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt1279 · Cited by 76 · see citing works

Box C/D snoRNP catalysed methylation is aided by additional pre‐rRNA base‐pairing

van Nues, R. W., Granneman, S., Kudla, G. R., Sloan, K. E., Chicken, M., Tollervey, D. W., & Watkins, N. J. (2011) · The EMBO Journal · doi:10.1038/emboj.2011.148 · Cited by 74 · see citing works

EF-G and EF4: translocation and back-translocation on the bacterial ribosome

Yamamoto, H., Qin, Y., Achenbach, J., Li, C., Kijek, J., Spahn, C. M. T., & Nierhaus, K. H. (2013) · Nature Reviews Microbiology · doi:10.1038/nrmicro3176 · Cited by 67 · see citing works

Quantitation of Human Ribosomal DNA: Hybridization of Human DNA with Ribosomal RNA for Quantitation and Fractionation

Schmickel, R. D. (1973) · Pediatric Research · doi:10.1203/00006450-197301000-00002 · Cited by 66 · see citing works

Mouse Ribosomal RNA Genes Contain Multiple Differentially Regulated Variants

Tseng, H., Chou, W., Wang, J., Zhang, X., Zhang, S., & Schultz, R. M. (2008) · PLoS ONE · doi:10.1371/journal.pone.0001843 · Cited by 66 · see citing works

Sequence variants from whole genome sequencing a large group of Icelanders

Gudbjartsson, D. F., Sulem, P., Helgason, H., Gylfason, A., Gudjonsson, S. A., Zink, F., Oddsson, Á., Magnusson, G., Halldórsson, B. V., Hjartarson, E., et al. (2015) · Scientific Data · doi:10.1038/sdata.2015.11 · Cited by 66 · see citing works

Characterization and Analysis of the Composition and Dynamics of the Mammalian Riboproteome

Reschke, M., Clohessy, J. G., Seitzer, N., Goldstein, D. P., Breitkopf, S. B., Schmolze, D. B., Ala, U., Asara, J. M., Beck, A. H., & Pandolfi, P. P. (2013) · Cell Reports · doi:10.1016/j.celrep.2013.08.014 · Cited by 65 · see citing works

Human ribosomal RNA variants from a single individual and their expression in different tissues

Kuo, B. A. (1996) · Nucleic Acids Research · doi:10.1093/nar/24.23.4817 · Cited by 54 · see citing works

Human 28S ribosomal RNA sequence heterogeneity

Gonzalez, I. L., Sylvester, J. E., & Schmickel, R. D. (1988) · Nucleic Acids Research · doi:10.1093/nar/16.21.10213 · Cited by 49 · see citing works

Genomic Characterization of the Mouse Ribosomal DNA Locus

Zentner, G. E., Balow, S. A., & Scacheri, P. C. (2013) · G3 Genes Genomes Genetics · doi:10.1534/g3.113.009290 · Cited by 45 · see citing works

The sequence of 28S ribosomal RNA varies within and between human cell lines

Leffers, H. C. B., & Andersen, A. H. (1993) · Nucleic Acids Research · doi:10.1093/nar/21.6.1449 · Cited by 44 · see citing works

Insights into the molecular determinants of EF-G catalyzed translocation

Wang, L., Altman, R. B., & Blanchard, S. C. (2011) · RNA · doi:10.1261/rna.029033.111 · Cited by 35 · see citing works

The SBP2 protein central to selenoprotein synthesis contacts the human ribosome at expansion segment 7L of the 28S rRNA

Kossinova, O. A., Malygin, A. A., Krol, A., & Karpova, G. G. (2014) · RNA · doi:10.1261/rna.044917.114 · Cited by 28 · see citing works

mTORC1-Driven Tumor Cells Are Highly Sensitive to Therapeutic Targeting by Antagonists of Oxidative Stress

Li, J., Shin, S., Sun, Y., Yoon, S.-O., Li, C., Zhang, E. Y., Yu, J. J., Zhang, J., & Blenis, J. (2016) · Cancer Research · doi:10.1158/0008-5472.can-15-2629 · Cited by 27 · see citing works

Subtractional Heterogeneity: A Crucial Step toward Defining Specialized Ribosomes

Briggs, J., & Dinman, J. D. (2017) · Molecular Cell · doi:10.1016/j.molcel.2017.06.022 · Cited by 25 · see citing works

Basonuclin Regulates a Subset of Ribosomal RNA Genes in HaCaT Cells

Zhang, S., Wang, J., & Tseng, H. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000902 · Cited by 23 · see citing works

All Ribosomes Are Created Equal. Really?

Preiß, T. (2015) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2015.11.009 · Cited by 21 · see citing works

The parable of the caveman and the Ferrari: protein synthesis and the RNA world

Noller, H. F. (2017) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2016.0187 · Cited by 11 · see citing works

New ribosomes for new memories?

Hernandez, A. I., Alarcón, J. M., & Allen, K. (2015) · Communicative & Integrative Biology · doi:10.1080/19420889.2015.1017163 · Cited by 8 · see citing works

Epigenetic Regulation of the Protein Translation Machinery

Holland, M. L. (2017) · EBioMedicine · doi:10.1016/j.ebiom.2017.02.018 · Cited by 8 · see citing works

Specialized Ribosomes: A New Frontier in Gene Regulation, Organismal Biology, & Evolution

Barna, M. (2017) · The FASEB Journal · doi:10.1096/fasebj.31.1_supplement.387.1 · Cited by 3 · see citing works

Specialized Ribosomes: A New Frontier in Gene Regulation, Organismal Biology, & Evolution

Barna, M. (2016) · Blood · doi:10.1182/blood.v128.22.sci-41.sci-41 · Cited by 2 · see citing works

The complete sequence of a human genome

Nurk, S., Koren, S., Rhie, A., Rautiainen, M., Bzikadze, A. V., Mikheenko, A., Vollger, M. R., Altemose, N., Uralsky, L., Gershman, A., et al. (2022) · Science · doi:10.1126/science.abj6987 · Cited by 3,136 · see citing works

RNA modifications modulate gene expression during development

Frye, M., Harada, B. T., Behm, M., & He, C. (2018) · Science · doi:10.1126/science.aau1646 · Cited by 1,258 · see citing works

The discovery of ribosome heterogeneity and its implications for gene regulation and organismal life

Genuth, N. R., & Barna, M. (2018) · Molecular Cell · doi:10.1016/j.molcel.2018.07.018 · Cited by 511 · see citing works

Landscape of the complete RNA chemical modifications in the human 80S ribosome

Taoka, M., Nobe, Y., Yamaki, Y., Sato, K., Ishikawa, H., Izumikawa, K., Yamauchi, Y., Hirota, K., Nakayama, H., Takahashi, N., et al. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky811 · Cited by 357 · see citing works

Ribosome Biogenesis: A Central Player in Cancer Metastasis and Therapeutic Resistance

Elhamamsy, A. R., Metge, B. J., Alsheikh, H. A., Shevde, L. A., & Samant, R. S. (2022) · Cancer Research · doi:10.1158/0008-5472.can-21-4087 · Cited by 320 · see citing works

Translation deregulation in human disease

Tahmasebi, S., Khoutorsky, A., Mathews, M. B., & Sonenberg, N. (2018) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-018-0034-x · Cited by 255 · see citing works

Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease

Prakash, V., Carson, B. B., Feenstra, J. M., Dass, R. A., Sekyrová, P., Hoshino, A., Petersen, J., Guo, Y., Parks, M., Kurylo, C. M., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-10100-8 · Cited by 222 · see citing works

Heterogeneity and specialized functions of translation machinery: from genes to organisms

Genuth, N. R., & Barna, M. (2018) · Nature Reviews Genetics · doi:10.1038/s41576-018-0008-z · Cited by 221 · see citing works

Hallmarks of ribosomopathies

Kampen, K. R., Sulima, S. O., Vereecke, S., & Keersmaecker, K. D. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz637 · Cited by 217 · see citing works

DNA methylation at the crossroads of gene and environment interactions

Law, P. P., & Holland, M. L. (2019) · Essays in Biochemistry · doi:10.1042/ebc20190031 · Cited by 148 · see citing works

Regulation of ribosomal RNA gene copy number, transcription and nucleolus organization in eukaryotes

Hori, Y., Engel, C., & Kobayashi, T. (2023) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-022-00573-9 · Cited by 147 · see citing works

Translational control through ribosome heterogeneity and functional specialization

Gay, D. M., Lund, A. H., & Jansson, M. D. (2022) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2021.07.001 · Cited by 141 · see citing works

Regulation of ribosome biogenesis in skeletal muscle hypertrophy

Figueiredo, V. C., & McCarthy, J. J. (2019) · Physiology · doi:10.1152/physiol.00034.2018 · Cited by 140 · see citing works

Does functional specialization of ribosomes really exist?

Ferretti, M., & Karbstein, K. (2019) · RNA · doi:10.1261/rna.069823.118 · Cited by 130 · see citing works

The Nucleolus: A Multiphase Condensate Balancing Ribosome Synthesis and Translational Capacity in Health, Aging and Ribosomopathies

Correll, C. C., Bártek, J., & Dundr, M. (2019) · Cells · doi:10.3390/cells8080869 · Cited by 124 · see citing works

Structural insights into nuclear transcription by eukaryotic DNA-dependent RNA polymerases

Girbig, M., Misiaszek, A. D., & Müller, C. W. (2022) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-022-00476-9 · Cited by 125 · see citing works

Pre-Ribosomal RNA Processing in Human Cells: From Mechanisms to Congenital Diseases

Aubert, M., O’Donohue, M.-F., Lebaron, S., & Gleizes, P. (2018) · Biomolecules · doi:10.3390/biom8040123 · Cited by 122 · see citing works

Endogenous rRNA Sequence Variation Can Regulate Stress Response Gene Expression and Phenotype

Kurylo, C. M., Parks, M. M., Juette, M. F., Zinshteyn, B., Altman, R. B., Thibado, J. K., Vincent, C. T., & Blanchard, S. C. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.08.093 · Cited by 117 · see citing works

Ribosome heterogeneity in stem cells and development

Li, D., & Wang, J. (2020) · The Journal of Cell Biology · doi:10.1083/jcb.202001108 · Cited by 109 · see citing works

Loss of m1acp3Ψ Ribosomal RNA Modification Is a Major Feature of Cancer

Babaian, A., Rothe, K., Girodat, D. J., Minia, I., Djondovic, S., Milek, M., Miko, S. E. S., Wieden, H., Landthaler, M., Morin, G. B., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.107611 · Cited by 110 · see citing works

Decoding the Function of Expansion Segments in Ribosomes

Fujii, K., Susanto, T. T., Saurabh, S., & Barna, M. (2018) · Molecular Cell · doi:10.1016/j.molcel.2018.11.023 · Cited by 106 · see citing works

Regulation of translation by site-specific ribosomal RNA methylation

Jansson, M., Häfner, S. J., Altinel, K., Tehler, D., Krogh, N., Jakobsen, E., Andersen, J. V., Andersen, K. L., Schoof, E. M., Ménard, P., et al. (2021) · Nature Structural & Molecular Biology · doi:10.1038/s41594-021-00669-4 · Cited by 106 · see citing works

Translational initiation in E. coli occurs at the correct sites genome-wide in the absence of mRNA-rRNA base-pairing

Saito, K., Green, R., & Buskirk, A. R. (2020) · eLife · doi:10.7554/elife.55002 · Cited by 99 · see citing works

SMN-primed ribosomes modulate the translation of transcripts related to spinal muscular atrophy

Lauria, F., Bernabò, P., Tebaldi, T., Groen, E. J. N., Perenthaler, E., Maniscalco, F., Rossi, A., Donzel, D., Clamer, M., Marchioretto, M., et al. (2020) · Nature Cell Biology · doi:10.1038/s41556-020-00577-7 · Cited by 98 · see citing works

Ribosome Stoichiometry: From Form to Function

Emmott, E., Jovanović, M., & Slavov, N. (2018) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2018.10.009 · Cited by 95 · see citing works

Nomenclature and Heterogeneity: Consequences for the Use of Mesenchymal Stem Cells in Regenerative Medicine

Wilson, A., Webster, A., & Genever, P. G. (2019) · Regenerative Medicine · doi:10.2217/rme-2018-0145 · Cited by 87 · see citing works

Emerging Role of Eukaryote Ribosomes in Translational Control

Venezia, N. D., Vincent, A., Marcel, V., Catez, F., & Diaz, J. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20051226 · Cited by 77 · see citing works

The conservation landscape of the human ribosomal RNA gene repeats

Agrawal, S., & Ganley, A. R. D. (2018) · PLoS ONE · doi:10.1371/journal.pone.0207531 · Cited by 76 · see citing works

The human ribosomal DNA array is composed of highly homogenized tandem clustersPreprint

Hori, Y., Shimamoto, A., & Kobayashi, T. (2021) · Genome Research · doi:10.1101/gr.275838.121 · Cited by 74 · see citing works

Ribosomal RNA 2′-O-methylation dynamics impact cell fate decisions

Häfner, S. J., Jansson, M., Altinel, K., Andersen, K. L., Abay-Nørgaard, Z., Ménard, P., Fontenas, M., Sørensen, D. M., Gay, D. M., Arendrup, F. S., et al. (2023) · Developmental Cell · doi:10.1016/j.devcel.2023.06.007 · Cited by 72 · see citing works

Dynamic regulation and requirement for ribosomal RNA transcription during mammalian development

Falcon, K. T., Watt, K. E. N., Dash, S., Zhao, R., Sakai, D., Moore, E. L., Fitriasari, S., Childers, M., Sardiu, M. E., Swanson, S. K., et al. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2116974119 · Cited by 69 · see citing works

Integrative rDNAomics—Importance of the Oldest Repetitive Fraction of the Eukaryote Genome

Symonová, R. (2019) · Genes · doi:10.3390/genes10050345 · Cited by 70 · see citing works

Selective translation by alternative bacterial ribosomes

Chen, Y., Xu, Z., Ge, X., Hong, J.-Y., Sanyal, S., Lu, Z. J., & Javid, B. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2009607117 · Cited by 68 · see citing works

Selective Autophagy of the Protein Homeostasis Machinery: Ribophagy, Proteaphagy and ER-Phagy

Beese, C. J., Brynjólfsdóttir, S. H., & Frankel, L. B. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2019.00373 · Cited by 65 · see citing works

Genetic and epigenetic regulation of skeletal muscle ribosome biogenesis with exercise

Figueiredo, V. C., Wen, Y., Alkner, B., Fernandez‐Gonzalo, R., Norrbom, J., Vechetti, I. J., Valentino, T., Mobley, C. B., Zentner, G. E., Peterson, C. A., et al. (2021) · The Journal of Physiology · doi:10.1113/jp281244 · Cited by 64 · see citing works

MetAP-like Ebp1 occupies the human ribosomal tunnel exit and recruits flexible rRNA expansion segments

Wild, K., Aleksić, M., Lapouge, K., Juaire, K. D., Flemming, D., Pfeffer, S., & Sinning, I. (2020) · Nature Communications · doi:10.1038/s41467-020-14603-7 · Cited by 63 · see citing works

The Role of WNT Pathway Mutations in Cancer Development and an Overview of Therapeutic Options

Groenewald, W., Lund, A. H., & Gay, D. M. (2023) · Cells · doi:10.3390/cells12070990 · Cited by 62 · see citing works

Human skeletal muscle fiber heterogeneity beyond myosin heavy chains

Moreno‐Justicia, R., der Stede, T. V., Stocks, B., Laitila, J. M., Seaborne, R. A. E., de Loock, A. V., Lievens, E., Samodova, D., Marín-Arraiza, L., Dmytriyeva, O., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-56896-6 · Cited by 61 · see citing works

RNA Polymerases I and III in development and disease

Watt, K. E. N., Macintosh, J., Bernard, G., & Trainor, P. A. (2022) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2022.03.027 · Cited by 58 · see citing works

Divergent rRNAs as regulators of gene expression at the ribosome level

Song, W., Joo, M., Yeom, J., Shin, E., Lee, M., Choi, H., Hwang, J., Kim, Y., Seo, R., Lee, J. E., et al. (2019) · Nature Microbiology · doi:10.1038/s41564-018-0341-1 · Cited by 57 · see citing works

Ribosome biogenesis in skeletal muscle: coordination of transcription and translation

von Walden, F. (2019) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00963.2018 · Cited by 57 · see citing works

Gene- and Species-Specific Hox mRNA Translation by Ribosome Expansion Segments

Leppek, K., Fujii, K., Quade, N., Susanto, T. T., Boehringer, D., Lenarčič, T., Xue, S., Genuth, N. R., Ban, N., & Barna, M. (2020) · Molecular Cell · doi:10.1016/j.molcel.2020.10.023 · Cited by 56 · see citing works

Prevalence and Phenotypic Impact of Robertsonian Translocations

Poot, M., & Hochstenbach, R. (2021) · Molecular Syndromology · doi:10.1159/000512676 · Cited by 56 · see citing works

N6-adenosine methylation of ribosomal RNA affects lipid oxidation and stress resistance

Liberman, N., O’Brown, Z. K., Earl, A., Boulias, K., Gerashchenko, M. V., Wang, S. Y., Fritsche, C. M., Fady, P.-E., Dong, A., Gladyshev, V. N., et al. (2020) · Science Advances · doi:10.1126/sciadv.aaz4370 · Cited by 53 · see citing works

Ribosome specialization and its potential role in the control of protein translation and skeletal muscle size

Chaillou, T. (2019) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00946.2018 · Cited by 50 · see citing works

Fourth Report on Chicken Genes and Chromosomes 2022

Smith, J., Alfieri, J. M., Anthony, N., Arensburger, P., Athrey, G., Balacco, J., Balic, A., Bardou, P., Barela, P., Bigot, Y., et al. (2022) · Cytogenetic and Genome Research · doi:10.1159/000529376 · Cited by 52 · see citing works

Diversity of ribosomes at the level of rRNA variation associated with human health and disease

Rothschild, D., Susanto, T. T., Sui, X., Spence, J. P., Rangan, R., Genuth, N. R., Sinnott-Armstrong, N., Wang, X., Pritchard, J. K., & Barna, M. (2024) · Cell Genomics · doi:10.1016/j.xgen.2024.100629 · Cited by 48 · see citing works

Sequencing of the Arabidopsis NOR2 reveals its distinct organization and tissue-specific rRNA ribosomal variants

Sims, J., Sestini, G., Elgert, C., von Haeseler, A., & Schlögelhofer, P. (2021) · Nature Communications · doi:10.1038/s41467-020-20728-6 · Cited by 47 · see citing works

Substitutions Are Boring: Some Arguments about Parallel Mutations and High Mutation Rates

Press, M. O., Hall, A. N., Morton, E. A., & Queitsch, C. (2019) · Trends in Genetics · doi:10.1016/j.tig.2019.01.002 · Cited by 46 · see citing works

rDNA array length is a major determinant of replicative lifespan in budding yeast

Hotz, M., Thayer, N. H., Hendrickson, D. G., Schinski, E. L., Xu, J., & Gottschling, D. E. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2119593119 · Cited by 46 · see citing works

T cells at work: How post‐transcriptional mechanisms control T cell homeostasis and activation

Jurgens, A. P., Popović, B., & Wolkers, M. C. (2021) · European Journal of Immunology · doi:10.1002/eji.202049055 · Cited by 39 · see citing works

Age-Dependent Ribosomal DNA Variations in Mice

Watada, E., Li, S., Hori, Y., Fujiki, K., Shirahige, K., Inada, T., & Kobayashi, T. (2020) · Molecular and Cellular Biology · doi:10.1128/mcb.00368-20 · Cited by 43 · see citing works

Thousands of high-quality sequencing samples fail to show meaningful correlation between 5S and 45S ribosomal DNA arrays in humans

Hall, A. N., Turner, T. N., & Queitsch, C. (2021) · Scientific Reports · doi:10.1038/s41598-020-80049-y · Cited by 43 · see citing works

First discovered, long out of sight, finally visible: ribosomal DNA

Hall, A. N., Morton, E. A., & Queitsch, C. (2022) · Trends in Genetics · doi:10.1016/j.tig.2022.02.005 · Cited by 43 · see citing works

Specialized Ribosomes in Health and Disease

Miller, S. C., MacDonald, C. C., Kellogg, M. K., Karamysheva, Z. N., & Karamyshev, A. L. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076334 · Cited by 42 · see citing works

Epitranscriptomic rRNA fingerprinting reveals tissue-of-origin and tumor-specific signatures

Milenkovic, I., Cruciani, S., Llovera, L., Lucas, M. C., Medina, R., Pauli, C., Heid, D., Muley, T., Schneider, M. A., Klotz, L. V., et al. (2024) · Molecular Cell · doi:10.1016/j.molcel.2024.11.014 · Cited by 38 · see citing works

Genetic variation at mouse and human ribosomal DNA influences associated epigenetic states

Rodríguez-Algarra, F., Seaborne, R. A. E., Danson, A. F., Yildizoglu, S., Yoshikawa, H., Law, P. P., Ahmad, Z., Maudsley, V. A., Brew, A., Holmes, N., et al. (2022) · Genome biology · doi:10.1186/s13059-022-02617-x · Cited by 38 · see citing works

Widespread genetic heterogeneity of human ribosomal RNA genes

Fan, W., Eklund, E., Sherman, R. M., Liu, H., Pitts, S. C., Ford, B. L., Rajeshkumar, N. V., & Laiho, M. (2022) · RNA · doi:10.1261/rna.078925.121 · Cited by 38 · see citing works

A subcellular map of translational machinery composition and regulation at the single-molecule level

Zhang, Z., Xu, A., Bai, Y., Chen, Y., Cates, K., Kerr, C. H., Bermudez, A., Susanto, T. T., Wysong, K., Garcia-Marques, F. J., et al. (2025) · Science · doi:10.1126/science.adn2623 · Cited by 38 · see citing works

Sequencing-based methods for detection and quantitation of ribose methylations in RNA

Krogh, N., & Nielsen, H. (2018) · Methods · doi:10.1016/j.ymeth.2018.11.017 · Cited by 37 · see citing works

Dynamic rRNA modifications as a source of ribosome heterogeneity

Milenkovic, I., & Novoa, E. M. (2024) · Trends in Cell Biology · doi:10.1016/j.tcb.2024.10.001 · Cited by 36 · see citing works

Fatal attraction: The roles of ribosomal proteins in the viral life cycle

Miller, C. M., Selvam, S., & Fuchs, G. (2020) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1613 · Cited by 36 · see citing works

P-stalk ribosomes act as master regulators of cytokine-mediated processes

Dopler, A., Alkan, F., Malka, Y., van der Kammen, R., Hoefakker, K., Taranto, D., Kocabay, N., Mimpen, I. L., Ramirez, C. F. A., Malzer, E., et al. (2024) · Cell · doi:10.1016/j.cell.2024.09.039 · Cited by 35 · see citing works

The 40 S -LARP1 complex reprograms the cellular translatome upon mTOR inhibition to preserve the protein synthetic capacity

Fuentes, P., Pelletier, J., Herraez, C. M., Díez‐Obrero, V., Iannizzotto, F., Rubio, T., Garcia‐Cajide, M., Menoyo, S., Moreno, V. R., Salazar, R., et al. (2021) · Science Advances · doi:10.1126/sciadv.abg9275 · Cited by 33 · see citing works

Invariable stoichiometry of ribosomal proteins in mouse brain tissues with aging

Amirbeigiarab, S., Kiani, P., Sanchez, A. K. V., Krisp, C., Kazantsev, A., Fester, L., Schlüter, H., & Ignatova, Z. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1912060116 · Cited by 33 · see citing works

Control of ribosomal RNA synthesis by hematopoietic transcription factors

Charles Antony, A., George, S. S., Blum, J., Somers, P., Thorsheim, C. L., Wu-Corts, D. J., Ai, Y., Gao, L., Lv, K., Tremblay, M. G., et al. (2022) · Molecular Cell · doi:10.1016/j.molcel.2022.08.027 · Cited by 32 · see citing works

Construction and validation of customized genomes for human and mouse ribosomal DNA mapping

George, S. S., Pimkin, M., & Paralkar, V. R. (2023) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2023.104766 · Cited by 32 · see citing works

N6-methyladenosine (m6A) modification of ribosomal RNAs (rRNAs): Critical roles in mRNA translation and diseases

Lei, K., Lin, S., & Yuan, Q. (2021) · Genes & Diseases · doi:10.1016/j.gendis.2021.10.005 · Cited by 32 · see citing works

rRNA and tRNA Bridges to Neuronal Homeostasis in Health and Disease

Tuorto, F., & Parlato, R. (2019) · Journal of Molecular Biology · doi:10.1016/j.jmb.2019.03.004 · Cited by 31 · see citing works

Short arms of human acrocentric chromosomes and the completion of the human genome sequencePreprint

Antonarakis, S. E. (2022) · Genome Research · doi:10.1101/gr.275350.121 · Cited by 31 · see citing works

Ribosome recycling in mRNA translation, quality control, and homeostasis

Nürenberg‐Goloub, E., & Tampé, R. (2019) · Biological Chemistry · doi:10.1515/hsz-2019-0279 · Cited by 30 · see citing works

Variability of Human rDNA

Smirnov, E., Chmúrčiaková, N., Liška, F., Bažantová, P., & Cmarko, D. (2021) · Cells · doi:10.3390/cells10020196 · Cited by 30 · see citing works

Genomic architecture of 5S rDNA cluster and its variations within and between species

Ding, Q., Li, R., Ren, X., Chan, L.-Y., Ho, V. W. S., Xie, D., Ye, P., & Zhao, Z. (2022) · BMC Genomics · doi:10.1186/s12864-022-08476-x · Cited by 29 · see citing works

Comparing methylation levels assayed in GC-rich regions with current and emerging methods

Guanzon, D., Ross, J. P., Ma, C., Berry, O., & Liew, Y. J. (2024) · BMC Genomics · doi:10.1186/s12864-024-10605-7 · Cited by 28 · see citing works

Challenges and Approaches to Genotyping Repetitive DNA

Morton, E. A., Hall, A. N., Kwan, E. X., Mok, C. A., Queitsch, K., Nandakumar, V., Stamatoyannopoulos, J. A., Brewer, B. J., Waterston, R., & Queitsch, C. (2019) · G3 Genes Genomes Genetics · doi:10.1534/g3.119.400771 · Cited by 25 · see citing works

Ribosomal DNA copy number is associated with body mass in humans and other mammals

Law, P. P., Mikheeva, L. A., Rodríguez-Algarra, F., Åsenius, F., Gregori, M., Seaborne, R. A. E., Yildizoglu, S., Miller, J. R. C., Tummala, H., Mesnage, R., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-49397-5 · Cited by 27 · see citing works

Fish genomics and its impact on fundamental and applied research of vertebrate biology

Ahmad, S. F., Jehangir, M., Srikulnath, K., & Martins, C. (2021) · Reviews in Fish Biology and Fisheries · doi:10.1007/s11160-021-09691-7 · Cited by 27 · see citing works

Tissue- and development-stage–specific mRNA and heterogeneous CNV signatures of human ribosomal proteins in normal and cancer samples

Panda, A., Yadav, A., Yeerna, H., Singh, A., Biehl, M. L., Lux, M., Schulz, A., Klecha, T., Doniach, S., Khiabanian, H., et al. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa485 · Cited by 25 · see citing works

Effective ribosomal RNA depletion for single-cell total RNA-seq by scDASH

Loi, D. S. C., Yu, L., & Wu, A. R. (2021) · PeerJ · doi:10.7717/peerj.10717 · Cited by 26 · see citing works

Early Detection of Lung Cancer Using Small RNAs

Sikosek, T., Horos, R., Trudzinski, F. C., Jehn, J., Frank, M., Rajakumar, T., Klotz, L. V., Mercaldo, N. D., Kahraman, M., Heuvelman, M., et al. (2023) · Journal of Thoracic Oncology · doi:10.1016/j.jtho.2023.07.005 · Cited by 25 · see citing works

Planktonic foraminifera genomic variations reflect paleoceanographic changes in the Arctic: evidence from sedimentary ancient DNA

Pawłowska, J., Wollenburg, J. E., Zajączkowski, M., & Pawlowski, J. W. (2020) · Scientific Reports · doi:10.1038/s41598-020-72146-9 · Cited by 26 · see citing works

The shift from early to late types of ribosomes in zebrafish development involves changes at a subset of rRNA 2′-O-Me sites

Ramachandran, S., Krogh, N., Jørgensen, T. E., Johansen, S., Nielsen, H., & Babiak, I. (2020) · RNA · doi:10.1261/rna.076760.120 · Cited by 25 · see citing works

Varying strength of selection contributes to the intragenomic diversity of rRNA genes

Sultanov, D., & Hochwagen, A. (2022) · Nature Communications · doi:10.1038/s41467-022-34989-w · Cited by 25 · see citing works

Learning-induced ribosomal RNA is required for memory consolidation in mice—Evidence of differentially expressed rRNA variants in learning and memory

Allen, K., Regier, M., Hsieh, C., Tsokas, P., Barnard, M., Phatarpekar, S., Wolk, J., Sacktor, T. C., Fenton, A. A., & Hernandez, A. I. (2018) · PLoS ONE · doi:10.1371/journal.pone.0203374 · Cited by 25 · see citing works

The story of rRNA expansion segments: Finding functionality amidst diversity

Hariharan, N., Ghosh, S., & Palakodeti, D. (2022) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1732 · Cited by 23 · see citing works

Comprehensive identification of diverse ribosomal RNA modifications by targeted nanopore direct RNA sequencing and JACUSA2

Vries, I. S. N., Zorbas, C., Lemsara, A., Piechotta, M., Ernst, F. G. M., Wacheul, L., Lafontaine, D. L. J., & Dieterich, C. (2023) · RNA Biology · doi:10.1080/15476286.2023.2248752 · Cited by 23 · see citing works

Ribosomal DNA copy number variation associates with hematological profiles and renal function in the UK Biobank

Rodríguez-Algarra, F., Evans, D. M., & Rakyan, V. K. (2024) · Cell Genomics · doi:10.1016/j.xgen.2024.100562 · Cited by 22 · see citing works

Implications of sequence variation on the evolution of rRNA

Parks, M., Kurylo, C. M., Batchelder, J. E., Vincent, C. T., & Blanchard, S. C. (2019) · Chromosome Research · doi:10.1007/s10577-018-09602-w · Cited by 21 · see citing works

Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome

Pellegrino, S., Meyer, M., Könst, Z. A., Holm, M., Voora, V. K., Kashinskaya, D., Zanette, C., Mobley, D. L., Yusupova, G. Z., Vanderwal, C. D., et al. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz053 · Cited by 20 · see citing works

Ribosomal DNA methylation in human and mouse oocytes increases with age

Potabattula, R., Trapphoff, T., Dittrich, M. T., Fic, K., Ptak, G., Dieterle, S., & Haaf, T. (2022) · Aging · doi:10.18632/aging.203891 · Cited by 19 · see citing works

Ribosomal heterogeneity – A new inroad for pharmacological innovation

Ford, D. (2020) · Biochemical Pharmacology · doi:10.1016/j.bcp.2020.113874 · Cited by 19 · see citing works

A Time‐Resolved Cryo‐EM Study of Saccharomyces cerevisiae 80S Ribosome Protein Composition in Response to a Change in Carbon Source

Sun, M., Shen, B., Li, W., Samir, P., Browne, C. M., Link, A. J., & Frank, J. (2020) · PROTEOMICS · doi:10.1002/pmic.202000125 · Cited by 18 · see citing works

VELCRO-IP RNA-seq reveals ribosome expansion segment function in translation genome-wide

Leppek, K., Byeon, G. W., Fujii, K., & Barna, M. (2021) · Cell Reports · doi:10.1016/j.celrep.2020.108629 · Cited by 18 · see citing works

The genomic structure of a human chromosome 22 nucleolar organizer region determined by TAR cloning

Kim, J., Noskov, V. N., Ogurtsov, A. Y., Nagaraja, R., Ns, P., Liskovykh, M. A., Walenz, B. P., Lee, H.-S., Kouprina, N., Phillippy, A. M., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-82565-x · Cited by 18 · see citing works

The Ribosomal Gene Loci—The Power behind the Throne

Panov, K. I., Hannan, K. M., Hannan, R. D., & Hein, N. (2021) · Genes · doi:10.3390/genes12050763 · Cited by 18 · see citing works

From correlation to causation: The new frontier of transgenerational epigenetic inheritance

Rothi, M. H., & Greer, E. L. (2022) · BioEssays · doi:10.1002/bies.202200118 · Cited by 17 · see citing works

Decoding Ribosome Heterogeneity: A New Horizon in Cancer Therapy

Gelfo, V., Venturi, G., Zacchini, F., & Montanaro, L. (2024) · Biomedicines · doi:10.3390/biomedicines12010155 · Cited by 17 · see citing works

Epitranscriptional m6A modification of rRNA negatively impacts translation and host colonization in Staphylococcus aureus

Shields, K. E., Ranava, D., Tan, Y., Zhang, D., & Yap, M.-N. F. (2024) · PLoS Pathogens · doi:10.1371/journal.ppat.1011968 · Cited by 17 · see citing works

Ribosome Structural Changes Dynamically Affect Ribosome Function

Lindahl, L. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252011186 · Cited by 17 · see citing works

The Expanding Riboverse

Sulima, S. O., & Dinman, J. D. (2019) · Cells · doi:10.3390/cells8101205 · Cited by 17 · see citing works

Impacts of ribosomal RNA sequence variation on gene expression and phenotype

Welfer, G. A., Brady, R. A., Natchiar, S. K., Watson, Z. L., Rundlet, E. J., Alejo, J. L., Singh, A. P., Mishra, N. K., Altman, R. B., & Blanchard, S. C. (2025) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2023.0379 · Cited by 11 · see citing works

Implications of sequence variation on the evolution of rRNA

Parks, M., Kurylo, C. M., Batchelder, J. E., Vincent, C. T., & Blanchard, S. C. (2019) · Chromosome Research · doi:10.1007/s10577-018-09602-w · Cited by 21 · see citing works

Human ribosomal RNA variants from a single individual and their expression in different tissues

Kuo, B. A. (1996) · Nucleic Acids Research · doi:10.1093/nar/24.23.4817 · Cited by 54 · see citing works

Sequence variation of human 28S rRNA and expression of variants in different tissues

Sylvester, J. E., Gonzalez, I. L., & Gillespie, D. A. (1994) · The American Journal of Human Genetics

Diversity of ribosomes at the level of rRNA variation associated with human health and disease

Rothschild, D., Susanto, T. T., Sui, X., Spence, J. P., Rangan, R., Genuth, N. R., Sinnott-Armstrong, N., Wang, X., Pritchard, J. K., & Barna, M. (2024) · Cell Genomics · doi:10.1016/j.xgen.2024.100629 · Cited by 48 · see citing works