Cited by 365Advanced Sensor and Energy Harvesting MaterialsHydrogels: synthesis, properties, applicationsConducting polymers and applications

Tissue-like skin-device interface for wearable bioelectronics by using ultrasoft, mass-permeable, and low-impedance hydrogels

Open access
Lim, Chanhyuk, Hong, Yongseok Joseph, Jung, Jaebong, Shin, Yoonsoo, Sunwoo, Sung-Hyuk, Baik, Seungmin, Park, Ok Kyu, Choi, Sueng Hong +4 more·2021·Science Advances

Abstract

A tissue-like skin-device interface was prepared by using ultrathin functionalized hydrogels for wearable bioelectronics.

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Crossref · 10.1126/sciadv.abd3716

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61 of 61 references verified0 citation errors · 0 not checkable

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  • Its softness and mechanical deformability allow it to adhere well to human skin, while the combination of a highly porous three-dimensional network and the super-low thickness of the interfacial hydrogel allows for rapid diffusion and transport of the target bioanalyte.

    “Its softness and mechanical deformability allow it to adhere well to human skin as shown in Fig. 10a-b, while the combination of a highly porous three-dimensional (3D) network and the super-low thickness of the interfacial hydrogel allows for rapid diffusion and transport of the target bioanalyte.”
  • Measurements are performed by first applying gentle heating to the skin across a hydrogel interface through which oxygen molecules are extracted from the blood vessels under the skin to reach the device; the diffused oxygen is then electrochemically reduced at the working electrode, and the change in reduction current is measured to obtain information about tcPO2.

    “As depicted in Fig. 10c, measurements are performed by first applying gentle heating to the skin across a hydrogel interface through which oxygen molecules are extracted from the blood vessels under the skin to reach the device. The diffused oxygen is then electrochemically reduced at the working electrode, and the change in reduction current is measured to obtain information about tcPO2.”
  • Kim and his team [230] propose a skin device interface with tissue-like characteristics formed by using an ultrathin type of functionalized hydrogel (PAM).

    “Kim and his team [230] propose a skin device interface with tissue-like characteristics that is formed by using an ultrathin type of functionalized hydrogel (PAM).”
  • By connecting this sensor to the human foot, it is capable of detecting the reduction current and tcPO2 at different foot positions, with a trend between them roughly as illustrated.

    “By connecting this sensor to the human foot (Fig. 10d), it is capable of detecting the reduction current and tcPO2 at different foot positions, with a trend between them roughly as illustrated in Fig. 10e-f.”

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2 of the 63 references couldn’t be matched to a known paper.

Research works printed but not linked: 2

  1. [40]Y.-L. Shen, in Constrained Deformation of Materials (Springer, Boston, ed. 1, 2010), pp. 47.
  2. [47]P. Sakunpongpitiporn, K. Phasuksom, N. Paradee, A. Sirivat, Facile synthesis of highly conductive PEDOT:PSSviasurfactant templates. RSC Adv. 9, 6363– 6378 (2019). PMC9060941 35517248

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Authors
Lim, C., Hong, Y. J., Jung, J., Shin, Y., Sunwoo, S.-H., Baik, S., Park, O. K., Choi, S. H., Hyeon, T., Kim, J. H., Lee, S., & Kim, D.-H.
Affiliations
  • Seoul National University (KR)
  • Pusan National University (KR)
  • Center for Nanoparticle Research, Institute for Basic Science (IBS), Seoul 08826, Republic of Korea.
  • Institute for Basic Science (KR)
Corresponding author
  • Lim, Chanhyuk
  • Hong, Yongseok Joseph
  • Jung, Jaebong
  • Kim, Ji Hoon
  • Lee, Sangkyu
  • Kim, Dae-Hyeong
Venue
Science Advances
Published
2021-05-07
Volume
7
Issue
19
ISSN
2375-2548 (ISSN-L)
OpenAlex
W3157047686
Cited by
365
References
63
Citations by year
2026: 58 · 2025: 91 · 2024: 86 · 2023: 66 · 2022: 53 · 2021: 11
FWCI
16.41
Type
journal article
Language
en
Open access
Locations
  • Science Advances (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • Seoul National University Open Repository (Seoul National University) (submittedVersion)
Funders
  • Ministry of Science and ICT, South Korea (IBS-R006-D1, IBS-R006-A1, 2019R1A5A6099595)
  • Institute of Basic Science (IBS-R006-D1, IBS-R006-A1)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Advanced Sensor and Energy Harvesting Materials
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Hydrogels: synthesis, properties, applications
  • Physical Sciences › Materials Science › Polymers and Plastics › Conducting polymers and applications
Keywords
wearable bioelectronics, functionalized hydrogels, liquid electrolytes, electrical stimulation, porous hydrogels, conformal interfaces

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