Cited by 378Memory and Neural MechanismsNeural dynamics and brain functionSpatial Cognition and Navigation

The Spatial Periodicity of Grid Cells Is Not Sustained During Reduced Theta Oscillations

Koenig, Julie, Linder, Ashley N., Leutgeb, Jill K., Leutgeb, Stefan·2011·Science

Abstract

Grid cell firing vanished after medial septum inhibition, while most hippocampal place cell firing was retained.

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Registry

Crossref · 10.1126/science.1201685

Cites

26 of 26 references verified0 citation errors · 0 not checkable

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  • Theta oscillations are not necessary for the emergence of the place code but play a major role in organizing place cell activity into temporal sequences that map available space and episodic events.

    “Theta oscillations—although not necessary for the emergence of the place code21,22—play a major role in organizing place cell activity into temporal sequences that map the available space (and, similarly, episodic events4,23,24).”

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Authors
Koenig, J., Linder, A. N., Leutgeb, J. K., & Leutgeb, S.
Affiliations
University of California San Diego (US)
Corresponding author
Leutgeb, Stefan
Venue
Science
Published
2011-04-29
Volume
332
Issue
6029
Pages
592-595
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W1981694662
Cited by
378
References
26
Citations by year
2026: 10 · 2025: 13 · 2024: 13 · 2023: 14 · 2022: 17 · 2021: 27 · 2020: 21 · 2019: 21 · 2018: 31 · 2017: 38 · 2016: 24 · 2015: 30 · 2014: 37 · 2013: 45 · 2012: 20
FWCI
19.31
Type
journal article
Language
en
Open access
closed
Locations
  • Science (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
  • Physical Sciences › Engineering › Automotive Engineering › Spatial Cognition and Navigation
Keywords
grid cells, theta oscillations, entorhinal cortex, parahippocampal cortex, place cells, hippocampus, spatial firing patterns, lidocaine, temporal oscillations, spatial memory, rats
MeSH terms
Animals, Hippocampus, Lidocaine, Male, Membrane Potentials, Motor Activity, Nerve Net, Neural Pathways, Neurons, Periodicity, Septum Pellucidum, Space Perception, Theta Rhythm, Entorhinal Cortex, Rats, Long-Evans, Rats

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