Biochemistry of Nitric Oxide and Its Redox-Activated Forms

Nitric oxide: physiology, pathophysiology, and pharmacology.

Moncada, S., Palmer, R. M., & Higgs, E. A. (1991) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06663-3 · Cited by 15,525

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

Palmer, R. M. J., Ferrige, A. G., & Moncada, S. (1987) · Nature · doi:10.1038/327524a0 · Cited by 10,704

Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide

Beckman, J. S., Beckman, T. W., Chen, J., Marshall, P. A., & Freeman, B. A. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.4.1620 · Cited by 7,029

Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

Ignarro, L. J., Buga, G. M., Wood, K. S., Byrns, R. E., & Chaudhuri, G. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.24.9265 · Cited by 5,074

Nitric oxide as a secretory product of mammalian cells

Nathan, C. (1992) · The FASEB Journal · doi:10.1096/fasebj.6.12.1381691 · Cited by 4,350

Peroxynitrite oxidation of sulfhydryls.

Radí, R., Beckman, J. S., Bush, K., & Freeman, B. Α. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)64313-7 · Cited by 2,492

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

Bredt, D. S., Hwang, P. M., Glatt, C. E., Lowenstein, C. J., Reed, R. R., & Snyder, S. H. (1991) · Nature · doi:10.1038/351714a0 · Cited by 2,354

Macrophage cytotoxicity: role for L-arginine deiminase and imino nitrogen oxidation to nitrite

Hibbs, J. B., Taintor, R. R., & Vavrin, Z. (1987) · Science · doi:10.1126/science.2432665 · Cited by 1,527

S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds.

Stamler, J. S., Simon, D. I., Osborne, J. A., Mullins, M. E., Jaraki, O., Michel, T. M., Singel, D. J., & Loscalzo, J. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.1.444 · Cited by 1,471

DNA Deaminating Ability and Genotoxicity of Nitric Oxide and its Progenitors

Wink, D. A., Kasprzak, K. S., Maragos, C. M., Elespuru, R. K., Misra, M., Dunams, T. M., Cebula, T. A., Koch, W. H., Andrews, A. W., Allen, J. S., et al. (1991) · Science · doi:10.1126/science.1948068 · Cited by 1,243

Suppression of NO production and 8-nitroguanosine formation by phenol-containing endocrine-disrupting chemicals in LPS-stimulated macrophages: Involvement of estrogen receptor-dependent or -independent pathways

Yoshitake, J., Kato, K., Yoshioka, D., Sueishi, Y., Sawa, T., Akaike, T., & Yoshimura, T. (2008) · Nitric Oxide · doi:10.1016/j.niox.2008.01.003 · Cited by 58

Nitric oxide synthase deficiency and the pathophysiology of muscular dystrophy

Tidball, J. G., & Wehling‐Henricks, M. (2014) · The Journal of Physiology · doi:10.1113/jphysiol.2014.274878 · Cited by 58

Suppression of nitric oxide toxicity in islet cells by α‐tocopherol

Burkart, V., Groβ-Eick, A., Bellmann, K., Radons, J., & Kolb, H. (1995) · FEBS Letters · doi:10.1016/0014-5793(95)00401-t · Cited by 58

Cytokines as Mediators of Autoimmune Diabetes and Diabetic Complications

PANKEWYCZ, O. G., Guan, J., & BENEDICT, J. F. (1995) · Endocrine Reviews · doi:10.1210/edrv-16-2-164 · Cited by 58

Óxido nítrico: revisão

Cerqueira, N. F., & Yoshida, W. B. (2002) · Acta Cirúrgica Brasileira · doi:10.1590/s0102-86502002000600011 · Cited by 64

Nitric Oxide Modulates Cardiac Na + Channel via Protein Kinase A and Protein Kinase G

Ahmmed, G. U., Xu, Y., Dong, P. H., Zhang, Z., Eiserich, J. P., & Chiamvimonvat, N. (2001) · Circulation Research · doi:10.1161/hh2301.100801 · Cited by 58

The reactivity of nitrosyl ruthenium complexes containing polypyridyl ligands

Sauaia, M. G., & da Silva, R. S. (2003) · Transition Metal Chemistry · doi:10.1023/a:1022964510682 · Cited by 58

NO as a signaling molecule: effects on kinases

Schindler, H., & Bogdan, C. (2001) · International Immunopharmacology · doi:10.1016/s1567-5769(01)00089-3 · Cited by 58

Vitamin C Augments the Inotropic Response to Dobutamine in Humans With Normal Left Ventricular Function

Mak, S. S., & Newton, G. E. (2001) · Circulation · doi:10.1161/01.cir.103.6.826 · Cited by 59

Expression of Inducible and Endothelial Nitric Oxide Synthases, Formation of Peroxynitrite and Reactive Oxygen Species in Human Chronic Renal Transplant Failure

Albrecht, E. W. J. A., Stegeman, C. A., Tiebosch, A. T. M. G., TEGZESS, A. M., & van Goor, H. (2002) · American Journal of Transplantation · doi:10.1034/j.1600-6143.2002.20509.x · Cited by 58

Reduced glutathione prevents nitric oxide-induced apoptosis in vascular smooth muscle cells

Zhao, Z., Francis, C. E., Welch, G. N., Loscalzo, J., & Ravid, K. (1997) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/s0167-4889(97)00093-1 · Cited by 58

The Therapeutic Potential of Nitric Oxide in Lung Transplantation

Meyer, K. C., Love, R. B., & Zimmerman, J. J. (1998) · CHEST Journal · doi:10.1378/chest.113.5.1360 · Cited by 58

Neuroprotective versus neurodestructive effects of NO‐related species

Lipton, S. A., Choi, Y., Sucher, N. J., & Chen, H.-S. V. (1998) · BioFactors · doi:10.1002/biof.5520080107 · Cited by 58

Unveiling the significance of inducible nitric oxide synthase: Its impact on cancer progression and clinical implications

Chen, T. (2024) · Cancer Letters · doi:10.1016/j.canlet.2024.216931 · Cited by 62

Nitric Oxide Storage and Transport in Cells Are Mediated by Glutathione S-Transferase P1-1 and Multidrug Resistance Protein 1 via Dinitrosyl Iron Complexes

Lok, H. C., Rahmanto, Y. S., Hawkins, C. L., Kalinowski, D. S., Morrow, C. S., Townsend, A. J., Ponka, P., & Richardson, D. R. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.310987 · Cited by 57

Endothelial dysfunctions: common denominators in vascular disease

Caterina, R. D. (2000) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/00075197-200011000-00007 · Cited by 57

Nitrogen Chemistry and Lung Physiology

Marozkina, N. V., & Gaston, B. M. (2015) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021113-170352 · Cited by 57

Relation of Cerebral Energy Metabolism and Extracellular Nitrite and Nitrate Concentrations in Patients after Aneurysmal Subarachnoid Hemorrhage

Sakowitz, O. W., Wolfrum, S., Sarrafzadeh, A. S., Stover, J., Dreier, J. P., Dendorfer, A., Benndorf, G., Lanksch, W., & Unterberg, A. W. (2001) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-200109000-00004 · Cited by 57

Theoretical and Experimental Study of Medium Effects on the Structure and Spectroscopy of the [Fe(CN)5NO]2- Ion

Estrin, D. A., Baraldo, L. M., Slep, L. D., Barja, B. C., Olabe, J. A., Paglieri, L., & Corongiu, G. (1996) · Inorganic Chemistry · doi:10.1021/ic951202c · Cited by 57

Nasal nitric oxide and nasal allergy

Struben, V. M. D., Wieringa, M. H., Feenstra, L., & de Jongste, J. C. (2006) · Allergy · doi:10.1111/j.1398-9995.2006.01096.x · Cited by 57

In Vitro and in vivo antioxidant effects of mustard leaf (Brassica juncea)

Kim, H. Y., Yokozawa, T., Cho, E. J., Cheigh, H. S., Choi, J. S., & Chung, H. Y. (2003) · Phytotherapy Research · doi:10.1002/ptr.1174 · Cited by 57

Enzymatic and nonenzymatic ADP-ribosylation of cysteine

McDonald, L. J., & Moss, J. (1994) · Molecular and Cellular Biochemistry · doi:10.1007/bf00928465 · Cited by 57

Peroxynitrite generated in the rat spinal cord induces oxidation and nitration of proteins: Reduction by Mn (III) tetrakis (4‐benzoic acid) porphyrin

Bao, F., DeWitt, D. S., Prough, D. S., & Liu, D. (2002) · Journal of Neuroscience Research · doi:10.1002/jnr.10481 · Cited by 57

Chaperone-like features of bovine serum albumin: a comparison with α-crystallin

Marini, I., Moschini, R., CORSO, A. D., & Mura, U. (2005) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-005-5397-4 · Cited by 57

Lambda Interferon (IFN-λ) in Serum Is Decreased in Hantavirus-Infected Patients, and In Vitro-Established Infection Is Insensitive to Treatment with All IFNs and Inhibits IFN-γ-Induced Nitric Oxide Production

Stoltz, M., Ahlm, C., Lundkvist, Å., & Klingström, J. (2007) · Journal of Virology · doi:10.1128/jvi.00415-07 · Cited by 57

The Vacuolar H+-ATPase of Clathrin-coated Vesicles Is Reversibly Inhibited by S-Nitrosoglutathione

Forgac, M. D. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.3.1301 · Cited by 57

Nitric Oxide Redox Species Exert Differential Permeability Effects on the Blood-Brain Barrier

Boje, K. M. K., & Lakhman, S. S. (2000) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)39267-5 · Cited by 59

Thermodynamics of reactions involving nitrogen-oxygen compounds

Koppenol, W. H. (1996) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(96)68005-7 · Cited by 57

Nitric Oxide Involvement inHydra vulgarisVery Primitive Olfactory-Like System

Colasanti, M., Venturini, G., Merante, A., Musci, G., & Lauro, G. M. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-01-00493.1997 · Cited by 57

The morphogenic/cytotoxic and prostaglandin-stimulating activities of interleukin-1 beta in the rat ovary are nitric oxide independent.

Ben‐Shlomo, I., Adashi, E. Y., & Payne, D. W. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117484 · Cited by 57

The interplay of nitric oxide and peroxynitrite with signal transduction pathways: Implications for disease

McAndrew, J., Patel, R. P., Jo, H., Cornwell, T., Lincoln, T., Moellering, D., White, C. R., Matalon, S., & Darley-Usmar, V. (1997) · Seminars in Perinatology · doi:10.1016/s0146-0005(97)80002-x · Cited by 56

Nitric oxide stimulates tyrosine phosphorylation in murine fibroblasts in the absence and presence of epidermal growth factor

Peranovich, T. M. S., da Silva, A. M., Fries, D. M., Stern, A., & Monteiro, H. P. (1995) · Biochemical Journal · doi:10.1042/bj3050613 · Cited by 56

A selective nitric oxide nanocomposite biosensor based on direct electron transfer of microperoxidase: Removal of interferences by co-immobilized enzymes

Abdelwahab, A. A., Koh, W. C. A., Noh, H., & Shim, Y. (2010) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2010.08.070 · Cited by 56

Complex-1 activity and 18F-DOPA uptake in genetically engineered mouse model of Parkinson's disease and the neuroprotective role of coenzyme Q10

SHARMA, S. K., Refaey, H. E., & Ebadi, M. (2005) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2005.11.019 · Cited by 56

Benzofuroxan and Furoxan. Chemistry and Biology

Cerecetto, H., & González, M. (2007) · Topics in heterocyclic chemistry · doi:10.1007/7081_2007_064 · Cited by 56

Induced Nitric Oxide Synthase as a Major Player in the Oncogenic Transformation of Inflamed Tissue

Yang, G., Taboada, S., & Liao, J. (2009) · Methods in molecular biology · doi:10.1007/978-1-60327-530-9_8 · Cited by 56

The yin and yang of nitric oxide: Reflections on the physiology and pathophysiology of NO�

Bentz, B. G., Simmons, R. L., Haines, G. K., & Radosevich, J. A. (2000) · Head & Neck · doi:10.1002/(sici)1097-0347(200001)22:1 · Cited by 56

Higher level of plasma nitric oxide in spontaneously hypertensive rats

Wu, C. C. (1999) · American Journal of Hypertension · doi:10.1016/s0895-7061(99)00008-4 · Cited by 56

Iron catalyzed conversion of NO into nitrosonium (NO+) and nitroxyl (HNO/NO−) species

Stojanović, S. Đ., Stanić-Vučinić, D., Nikolic, M. R., Spasić, M. B., & Niketić, V. (2004) · Nitric Oxide · doi:10.1016/j.niox.2004.09.007 · Cited by 56

Localization of putative nitrergic neurons in peripheral chemosensory areas and the central nervous system ofAplysia californica

Moroz, L. L. (2006) · The Journal of Comparative Neurology · doi:10.1002/cne.20842 · Cited by 56

Intrinsic radiosensitivity of human pancreatic tumour cells and the radiosensitising potency of the nitric oxide donor sodium nitroprusside

Verovski, V. N., den Berge, D. V., Soete, G., Bols, B., & Storme, G. A. (1996) · British Journal of Cancer · doi:10.1038/bjc.1996.623 · Cited by 56

A Theoretical Study of Axial Tilting and Equatorial Asymmetry in Metalloporphyrin−Nitrosyl Complexes

Ghosh, A., & Wondimagegn, T. (2000) · Journal of the American Chemical Society · doi:10.1021/ja000747p · Cited by 56

The Reaction of S-Nitrosoglutathione with Superoxide

Jourd’heuil, D., Mai, C. T., Laroux, F. S., Wink, D. A., & Grisham, M. B. (1998) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.8227 · Cited by 56

Reaction of Human Myoglobin and Nitric Oxide

Witting, P. K., Douglas, D. J., & Mauk, A. G. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m005758200 · Cited by 56

Ligand and medium controlled photochemistry of iron and ruthenium mixed-ligand complexes: prospecting for versatile systems

Szacilowski, K. T., Macyk, W., Stochel, G., Stasicka, Z., Sostero, S., & Traverso, O. (2000) · Coordination Chemistry Reviews · doi:10.1016/s0010-8545(00)00328-3 · Cited by 56

Nitric Oxide Signaling Mediates Stimulation of L-Type Ca2+ Current Elicited by Withdrawal of Acetylcholine in Cat Atrial Myocytes

Wang, Y. G., Rechenmacher, C. E., & Lipsius, S. L. (1998) · The Journal of General Physiology · doi:10.1085/jgp.111.1.113 · Cited by 56

Rapid Attenuation of AP-1 Transcriptional Factors Associated with Nitric Oxide (NO)-mediated Neuronal Cell Death

Tablchi, A., Oh, E. S., Taoka, A., Sakurai, H., Tsuchiya, T., & Tsuda, M. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.49.31061 · Cited by 56

Cystatins of filarial nematodes up‐regulate the nitric oxide production of interferon‐γ‐activated murine macrophages

Hartmann, S., Schönemeyer, A., Sonnenburg, B., Vray, B., & Lucius, R. (2002) · Parasite Immunology · doi:10.1046/j.1365-3024.2002.00459.x · Cited by 55

Mechanisms of TLR4-Mediated Autophagy and Nitroxidative Stress

Zhang, K., Huang, Q., Deng, S., Yang, Y., Li, J., & Wang, S. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.766590 · Cited by 58

The mechanism of nitrogen monoxide (NO)‐mediated iron mobilization from cells

Watts, R., & Richardson, D. R. (2002) · European Journal of Biochemistry · doi:10.1046/j.1432-1033.2002.02987.x · Cited by 55

Effects of nitric oxide and oxidation in vivo and postmortem on meat tenderness

Warner, R. D., Dunshea, F. R., Ponnampalam, E. N., & Cottrell, J. J. (2005) · Meat Science · doi:10.1016/j.meatsci.2005.04.008 · Cited by 57

Effect of nitric oxide production and oxygen tension on progenitor preservation in ex vivo culture

Reykdal, S., Abboud, C. N., & Liesveld, J. L. (1999) · Experimental Hematology · doi:10.1016/s0301-472x(98)00030-7 · Cited by 55

Protective Effect of S-Nitrosylated α1-Protease Inhibitor on Hepatic Ischemia-Reperfusion Injury

Ikebe, N., Akaike, T., Miyamoto, Y., Hayashida, K., Yoshitake, J., Ogawa, M., & Maeda, H. (2000) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)38988-8 · Cited by 55

CsA and FK506 up-regulate eNOS expression: Role of reactive oxygen species and AP-1

Navarro-Antolı́n, J., Hernández‐Perera, O., López‐Ongil, S., Rodrı́guez-Puyol, M., Rodrı́guez-Puyol, D., & Lamas, S. (1998) · Kidney International · doi:10.1046/j.1523-1755.1998.06807.x · Cited by 55

cGMP inhibits IP 3 ‐induced Ca 2+ release in intact rat megakaryocytes via cGMP‐ and cAMP‐dependent protein kinases

Tertyshnikova, S., Yan, X., & Fein, A. (1998) · The Journal of Physiology · doi:10.1111/j.1469-7793.1998.089bf.x · Cited by 55

The Physiological Activity and In Vivo Distribution of Dinitrosyl Dithiolato Iron Complex

Ueno, T., & Yoshimura, T. (2000) · The Japanese Journal of Pharmacology · doi:10.1254/jjp.82.95 · Cited by 55

Nitric Oxide Modification of Rat Brain Neurogranin Affects Its Phosphorylation by Protein Kinase C and Affinity for Calmodulin

Sheu, F., Mahoney, C. W., Seki, K., & Huang, K. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.37.22407 · Cited by 55

Inhibition of sphincter of Oddi function by the nitric oxide carrier S-nitroso-N-acetylcysteine in rabbits and humans.

Slivka, A., Chuttani, R., Carr-Locke, D. L., Kobzik, L., Bredt, D. S., Loscalzo, J., & Stamler, J. S. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117527 · Cited by 55

Inhaled nitric oxide: role in the pathophysiology of cardio-cerebrovascular and respiratory diseases

Signori, D., Magliocca, A., Hayashida, K., Graw, J. A., Malhotra, R. K., Bellani, G., Berra, L. M., & Rezoagli, E. (2022) · Intensive Care Medicine Experimental · doi:10.1186/s40635-022-00455-6 · Cited by 54

Neutral and reduced Roussin's red salt ester [Fe 2 (μ-RS) 2 (NO) 4 ] (R = n-Pr, t-Bu, 6-methyl-2-pyridyl and 4,6-dimethyl-2-pyrimidyl): synthesis, X-ray crystal structures, spectroscopic, electrochemical and density functional theoretical investigations

Wang, R., Camacho-Fernandez, M. A., Xu, W., Zhang, J., & Li, L. (2008) · Dalton Transactions · doi:10.1039/b810230a · Cited by 54

Nitrate-to-Nitrite-to-Nitric Oxide Conversion Modulated by Nitrate-Containing {Fe(NO)2}9 Dinitrosyl Iron Complex (DNIC)

Tsai, F., Lee, Y., Chiang, M., & Liaw, W. (2012) · Inorganic Chemistry · doi:10.1021/ic3023437 · Cited by 54

Oxidative metabolism in sepsis and sepsis syndrome

Taylor, D. E., & Piantadosi, C. A. (1995) · Journal of Critical Care · doi:10.1016/0883-9441(95)90003-9 · Cited by 54

S-Nitrosylation and uncompetitive/fast off-rate (UFO) drug therapy in neurodegenerative disorders of protein misfolding

Nakamura, T., & Lipton, S. A. (2007) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4402138 · Cited by 54

ACE Inhibition, Endothelial Function and Coronary Artery Lesions

Mombouli, J. (1997) · Drugs · doi:10.2165/00003495-199700545-00004 · Cited by 54

Redox state, NMDA receptors and NO-related species

Lipton, S. A., Choi, Y., Sucher, N. J., Pan, Z., & Stamler, J. S. (1996) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(96)20028-8 · Cited by 54

Induction of nitric oxide release by MRC OX-44 (anti-CD53) through a protein kinase C-dependent pathway in rat macrophages.

Boscá, L., & Lazo, P. A. (1994) · The Journal of Experimental Medicine · doi:10.1084/jem.179.4.1119 · Cited by 54

Effects of Nitrate Supplementation on Exercise Performance in Humans: A Narrative Review

Macuh, M., & Knap, B. (2021) · Nutrients · doi:10.3390/nu13093183 · Cited by 53

S-nitrosylation-mediated activation of a histidine kinase represses the type 3 secretion system and promotes virulence of an enteric pathogen

Gu, D., Zhang, Y., Wang, Q., & Zhou, X. (2020) · Nature Communications · doi:10.1038/s41467-020-19506-1 · Cited by 53

Effective reduction of biofilm through photothermal therapy by gold core@shell based mesoporous silica nanoparticles

García, A., González, B., Harvey, C. M., Izquierdo‐Barba, I., & Vallet‐Regí, M. (2021) · Microporous and Mesoporous Materials · doi:10.1016/j.micromeso.2021.111489 · Cited by 53

Widely Differing Photochemical Behavior in Related Octahedral {Ru-NO}6Compounds: Intramolecular Redox Isomerism of the Excited State Controlling the Photodelivery of NO

Candia, A. G. D., Marcolongo, J. P., Etchenique, R., & Slep, L. D. (2010) · Inorganic Chemistry · doi:10.1021/ic100491g · Cited by 53

Anti-inflammatory activities of crocetin derivatives from processed Gardenia jasminoides

Hong, Y.-J., & Yang, K. (2013) · Archives of Pharmacal Research · doi:10.1007/s12272-013-0128-0 · Cited by 54

Nitric Oxide: Perspectives and Emerging Studies of a Well Known Cytotoxin

Paradise, W. A., Vesper, B. J., Goel, A., Waltonen, J. D., Altman, K. W., Haines, G. K., & Radosevich, J. A. (2010) · International Journal of Molecular Sciences · doi:10.3390/ijms11072715 · Cited by 55

Peroxynitrite mediates programmed cell death both in papillar cells and in self-incompatible pollen in the olive (Olea europaea L.)

Serrano, I., Romero‐Puertas, M. C., Rodríguez‐Serrano, M., Sandalio, L. M., & Olmedilla, A. (2011) · Journal of Experimental Botany · doi:10.1093/jxb/err392 · Cited by 53

Differential Clearance and Immune Responses to Tick Cell-Derived versus Macrophage Culture-DerivedEhrlichia chaffeensisin Mice

Ganta, R. R., Cheng, C., Miller, E. C., McGuire, B. L., Peddireddi, L., Sirigireddy, K. R., & Chapes, S. K. (2006) · Infection and Immunity · doi:10.1128/iai.01127-06 · Cited by 53

Functional Mononitrosyl Diiron(II) Complex Mediates the Reduction of NO to N2O with Relevance for Flavodiiron NO Reductases

Jana, M., Pal, N., White, C. J., Küpper, C., Meyer, F., Lehnert, N., & Majumdar, A. (2017) · Journal of the American Chemical Society · doi:10.1021/jacs.7b08855 · Cited by 53

Use of gasotransmitters for the controlled release of polymer-based nitric oxide carriers in medical applications

Yang, C., Jeong, S., Ku, S., Lee, K., & Park, M. H. (2018) · Journal of Controlled Release · doi:10.1016/j.jconrel.2018.04.025 · Cited by 54

Nitric oxide diffusion coefficients in solutions, proteins and membranes determined by phosphorescence

Vanderkooi, J. M., Wright, W. W., & Erecińska, M. (1994) · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · doi:10.1016/0167-4838(94)00073-5 · Cited by 53

Enhanced Pulmonary Response to the Inhalation of Freshly Fractured Silica as Compared with Aged Dust Exposure

Castranova, V., Pailes, W. H., Dalai, N. S., Miles, P. R., Bowman, L. L., Vallyathan, V., Pack, D., Weber, K. C., Hubbs, A. F., Schwegler‐Berry, D., et al. (1996) · Applied Occupational and Environmental Hygiene · doi:10.1080/1047322x.1996.10389993 · Cited by 53

Nitric oxide stimulates tyrosine phosphorylation of focal adhesion kinase, SRC kinase, and mitogen-activated protein kinases in murine fibroblasts

Monteiro, H. P., Gruia-Gray, J., Peranovich, T. M. S., de Oliveira, L. C. B., & Stern, A. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(99)00233-6 · Cited by 53

Induction of nitric oxide synthase is involved in the mechanism of Fas‐mediated apoptosis in haemopoietic cells

Selleri, C., Sato, T., Raiola, A. M., Rotoli, B., Young, N. S., & Maciejewski, J. P. (1997) · British Journal of Haematology · doi:10.1046/j.1365-2141.1996.4323240.x · Cited by 53

S-Adenosylmethionine modulates inducible nitric oxide synthase gene expression in rat liver and isolated hepatocytes

Majano, P. L., García‐Monzón, C., García–Trevijano, E. R., Corrales, F. J., Cámara, J., Ortiz, P., Mato, J. M., Avila, M. A., & Moreno‐Otero, R. (2001) · Journal of Hepatology · doi:10.1016/s0168-8278(01)00208-2 · Cited by 53

The Effect of Inhaled Nitric Oxide on the Pulmonary Circulation of the Neonatal Pig

Nelin, L. D., Moshin, J., Thomas, C. J., Sasidharan, P., & DAWSON, C. A. (1994) · Pediatric Research · doi:10.1203/00006450-199401000-00006 · Cited by 53

Giant identified NO-releasing neurons and comparative histochemistry of putative nitrergic systems in gastropod molluscs

Moroz, L. L. (2000) · Microscopy Research and Technique · doi:10.1002/1097-0029(20000615)49:6 · Cited by 53

Nitric Oxide Activates the Glucose-dependent Mobilization of Arachidonic Acid in a Macrophage-like Cell Line (RAW 264.7) That Is Largely Mediated by Calcium-independent Phospholipase A2

Gross, R. W., Rudolph, A. E., Wang, J., Sommers, C. D., & Wolf, M. J. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.25.14855 · Cited by 53

Transcription Factors as the “Blitzkrieg” of Plant Defense: A Pragmatic View of Nitric Oxide’s Role in Gene Regulation

Falak, N., Imran, Q. M., Hussain, A., & Yun, B. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22020522 · Cited by 54

Nitric oxide signaling and homeostasis in plants: a focus on nitrate reductase and S-nitrosoglutathione reductase in stress-related responses

Salgado, I., Martı́nez, M. C., Oliveira, H. C., & Frungillo, L. (2013) · Revista Brasileira de Botânica · doi:10.1007/s40415-013-0013-6 · Cited by 55

Macrolide antibiotics improve chemotactic and phagocytic capacity as well as reduce inflammation in sulfur mustard-exposed monocytes

Gao, X., Ray, R., Xiao, Y., Ishida, K., & Ray, P. (2009) · Pulmonary Pharmacology & Therapeutics · doi:10.1016/j.pupt.2009.10.010 · Cited by 52

Aerobic oxidative iodination of ketones catalysed by sodium nitrite “on water” or in a micelle-based aqueous system

Stavber, G., Iskra, J., Zupan, M., & Stavber, S. (2009) · Green Chemistry · doi:10.1039/b902230a · Cited by 52

[22] Chemical approaches toward generation of nitroxyl

King, S. B., & Nagasawa, H. T. (1999) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(99)01084-8 · Cited by 52

Rat cerebellar granule cells are protected from glutamate-induced excitotoxicity by S-nitrosoglutathione but not glutathione

Li, C.-Y., Chin, T., & Chueh, S. (2004) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00127.2003 · Cited by 52

Eyeblink conditioning, motor control, and the analysis of limbic-cerebellar interactions

Weiss, C., & Disterhoft, J. F. (1996) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00081929 · Cited by 54

Capillary Electrophoresis Analysis of Nitric Oxide Synthase Related Metabolites in Single Identified Neurons

Floyd, P. D., Moroz, L. L., Gillette, R., & Sweedler, J. V. (1998) · Analytical Chemistry · doi:10.1021/ac9713013 · Cited by 52

Regulation of Nitric Oxide Production by Tetrahydrobiopterin

Scott‐Burden, T. (1995) · Circulation · doi:10.1161/01.cir.91.1.248 · Cited by 52

Determinants of Shear Stress-Stimulated Endothelial Nitric Oxide Production Assessed in Real-Time by 4,5-Diaminofluorescein Fluorescence

Qiu, W., Kass, D. A., Hu, Q., & Ziegelstein, R. C. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.5401 · Cited by 52

Nitric oxide: basic science and clinical applications

Kam, P. C. A., & GOVENDER, G. (1994) · Anaesthesia · doi:10.1111/j.1365-2044.1994.tb03525.x · Cited by 52

Transmitter-induced calcium signalling in cultured neurons of the insect brain

Bicker, G. (1996) · Journal of Neuroscience Methods · doi:10.1016/s0165-0270(96)00018-0 · Cited by 52

Distinct effects of recombinant tenascin-C domains on neuronal cell adhesion, growth cone guidance, and neuronal polarity

D�rries, U., Taylor, J., Xiao, Z., Lochter, A., Montag, D., & Schachner, M. (1996) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19960215)43:4 · Cited by 62

cGMP-independent mechanism of airway smooth muscle relaxation induced by S -nitrosoglutathione

Perkins, W. J., Pabelick, C. M., Warner, D. O., & Jones, K. A. (1998) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1998.275.2.c468 · Cited by 52

NO+, but not NO⋅, inhibits respiratory oscillations in ethanol‐grown chemostat cultures of Saccharomyces cerevisiae

Murray, D. B., Engelen, F., Keulers, M., Kuriyama, H., & Lloyd, D. (1998) · FEBS Letters · doi:10.1016/s0014-5793(98)00777-7 · Cited by 52

Nitric Oxide Inhibits CPP32-like Activity under Redox Regulation

Ogura, T., Tatemichi, M., & Esumi, H. (1997) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1997.6948 · Cited by 52

The Evolution of Nitric Oxide Function: From Reactivity in the Prebiotic Earth to Examples of Biological Roles and Therapeutic Applications

Shepherd, M., Giordano, D., Verde, C., & Poole, R. K. (2022) · Antioxidants · doi:10.3390/antiox11071222 · Cited by 20

Chemical biology of nitric oxide: Regulation and protective and toxic mechanisms

Wink, D. A., Hanbauer, I., Grisham, M. B., Laval, F., Nims, R. W., Laval, J., Cook, J. C., Pacelli, R., Liebmann, J., Krishna, M. C., et al. (1996) · Current topics in cellular regulation · doi:10.1016/s0070-2137(96)80006-9 · Cited by 288

Biochemistry of Nitric Oxide and Peroxynitrite: Sources, Targets and Biological Implications

Aicardo, A., Martinez, D. M., Campolo, N., Bartesaghi, S., & Radí, R. (2016) · Springer eBooks · doi:10.1007/978-3-319-45865-6_5 · Cited by 21

Biochemical targets of nitric oxide-induced toxicity.

Grudziński, I. P. (2003) · PubMed · Cited by 3

The Chemical Properties of Nitric Oxide and Related Nitrogen Oxides

Fukuto, J. M., Cho, J. Y., & Switzer, C. H. (2000) · Elsevier eBooks · doi:10.1016/b978-012370420-7/50003-4 · Cited by 79