Biochemistry of Nitric Oxide and Its Redox-Activated Forms

Nitric oxide: physiology, pathophysiology, and pharmacology.

Moncada, S., Palmer, R. M., & Higgs, E. A. (1991) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06663-3 · Cited by 15,525

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

Palmer, R. M. J., Ferrige, A. G., & Moncada, S. (1987) · Nature · doi:10.1038/327524a0 · Cited by 10,704

Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide

Beckman, J. S., Beckman, T. W., Chen, J., Marshall, P. A., & Freeman, B. A. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.4.1620 · Cited by 7,029

Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

Ignarro, L. J., Buga, G. M., Wood, K. S., Byrns, R. E., & Chaudhuri, G. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.24.9265 · Cited by 5,074

Nitric oxide as a secretory product of mammalian cells

Nathan, C. (1992) · The FASEB Journal · doi:10.1096/fasebj.6.12.1381691 · Cited by 4,350

Peroxynitrite oxidation of sulfhydryls.

Radí, R., Beckman, J. S., Bush, K., & Freeman, B. Α. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)64313-7 · Cited by 2,492

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

Bredt, D. S., Hwang, P. M., Glatt, C. E., Lowenstein, C. J., Reed, R. R., & Snyder, S. H. (1991) · Nature · doi:10.1038/351714a0 · Cited by 2,354

Macrophage cytotoxicity: role for L-arginine deiminase and imino nitrogen oxidation to nitrite

Hibbs, J. B., Taintor, R. R., & Vavrin, Z. (1987) · Science · doi:10.1126/science.2432665 · Cited by 1,527

S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds.

Stamler, J. S., Simon, D. I., Osborne, J. A., Mullins, M. E., Jaraki, O., Michel, T. M., Singel, D. J., & Loscalzo, J. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.1.444 · Cited by 1,471

DNA Deaminating Ability and Genotoxicity of Nitric Oxide and its Progenitors

Wink, D. A., Kasprzak, K. S., Maragos, C. M., Elespuru, R. K., Misra, M., Dunams, T. M., Cebula, T. A., Koch, W. H., Andrews, A. W., Allen, J. S., et al. (1991) · Science · doi:10.1126/science.1948068 · Cited by 1,243

Nanocarriers for Nitric Oxide Delivery

Saraiva, J., Marotta-Oliveira, S. S., Cicillini, S. A., Eloy, J. O., & Marchetti, J. M. (2011) · Journal of Drug Delivery · doi:10.1155/2011/936438 · Cited by 67

The Insulin-Like Growth Factor Family: Molecular Mechanisms, Redox Regulation, and Clinical Implications

Vardatsikos, G., Sahu, A., & Srivastava, A. K. (2008) · Antioxidants and Redox Signaling · doi:10.1089/ars.2008.2161 · Cited by 67

The contribution of nitric oxide and interferon gamma to the regulation of the neuro-inflammation in experimental autoimmune encephalomyelitis

Willenborg, D. O., Staykova, M. A., Fordham, S., O’Brien, N. C., & Liñares, D. (2007) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2007.09.007 · Cited by 66

Hemoglobin and free radicals: implications for the development of a safe blood substitute

Alayash, A. I., & Cashon, R. E. (1995) · Molecular Medicine Today · doi:10.1016/s1357-4310(95)80089-1 · Cited by 66

Nitrogen Monoxide (NO) Storage and Transport by Dinitrosyl-Dithiol-Iron Complexes: Long-lived NO That Is Trafficked by Interacting Proteins

Rahmanto, Y. S., Kalinowski, D. S., Lane, D. J. R., Lok, H. C., Richardson, V., & Richardson, D. R. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.r111.329847 · Cited by 68

FluorescentJ-type Aggregates and Thermotropic Columnar Mesophases of Perylene Bisimide Dyes

Würthner, F., Thalacker, C., Diele, S., & Tschierske, C. (2001) · Chemistry - A European Journal · doi:10.1002/1521-3765(20010518)7:10 · Cited by 588

Monosodium Urate Crystals Synergize with IFN-γ to Generate Macrophage Nitric Oxide: Involvement of Extracellular Signal-Regulated Kinase 1/2 and NF-κB

Jaramillo, M., Naccache, P. H., & Olivier, M. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.9.5734 · Cited by 66

AIDS‐Related Dementia and Calcium Homeostasisa

Lipton, S. A. (1994) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1994.tb44411.x · Cited by 66

NO stimulation of ATP-sensitive potassium channels: Involvement of Ras/mitogen-activated protein kinase pathway and contribution to neuroprotection

Lin, Y., Raab‐Graham, K. F., Jan, Y. N., & Jan, L. Y. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402496101 · Cited by 66

The platelet-endothelium interaction mediated by lectin-like oxidized low-density lipoprotein receptor-1 reduces the intracellular concentration of nitric oxide in endothelial cells

Cominacini, L., Pasini, A. F., Garbin, U., Pastorino, A. M., Rigoni, A. M., Nava, C., Davoli, A., Cascio, V. L., & Sawamura, T. (2003) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(02)02811-5 · Cited by 67

Nitric Oxide and Bronchial Hyperresponsiveness

Nijkamp, F. P., & Folkerts, G. (2000) · Birkhäuser Basel eBooks · doi:10.1007/978-3-0348-8474-7_6 · Cited by 66

Non-Enzymatic Production of Nitric Oxide (NO) from NO Synthase Inhibitors

Moroz, L. L., Norby, S. W., Cruz, L., Sweedler, J. V., Gillette, R., & Clarkson, R. B. (1998) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.9810 · Cited by 66

The aromatization of Hantzsch dihydropyridines with nitric oxide (NO)

Itoh, T., Nagata, K., OKADA, M., & Ohsawa, A. (1995) · Tetrahedron Letters · doi:10.1016/0040-4039(95)00268-h · Cited by 66

Nitric oxide-releasing/generating polymers for the development of implantable chemical sensors with enhanced biocompatibility

Wu, Y., & Meyerhoff, M. E. (2008) · Talanta · doi:10.1016/j.talanta.2007.06.022 · Cited by 65

Role of nitric oxide in liver regeneration

Carnovale, C. E., & Ronco, M. T. (2012) · Annals of Hepatology · doi:10.1016/s1665-2681(19)31436-x · Cited by 65

A nitric oxide biosensor based on the multi-assembly of hemoglobin/montmorillonite/polyvinyl alcohol at a pyrolytic graphite electrode

Pang, J., Fan, C., Liu, X., Chen, T., & Li, G. (2003) · Biosensors and Bioelectronics · doi:10.1016/s0956-5663(03)00223-9 · Cited by 65

Fluvastatin Alters Platelet Aggregability in Patients With Hypercholesterolemia

Haramaki, N., Ikeda, H., Takenaka, K., Katoh, A., Sugano, R., Yamagishi, S., Matsuoka, H., & Imaizumi, T. (2007) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.106.128793 · Cited by 65

Role of oxidative stress in the pathophysiology of Toxoplasma gondii infection

Dinçel, G. Ç., & Atmaca, H. (2016) · International Journal of Immunopathology and Pharmacology · doi:10.1177/0394632016638668 · Cited by 65

N-Acetyl-cysteine modulates inducible nitric oxide synthase gene expression in human hepatocytes

Majano, P. L., Medina, J., Zubı́a, I., Sunyer, L., Lara‐Pezzi, E., Maldonado-Rodrı́guez, A., López‐Cabrera, M., & Moreno‐Otero, R. (2004) · Journal of Hepatology · doi:10.1016/j.jhep.2003.12.009 · Cited by 65

Protection of Endothelial Function: Targets for Nutritional and Pharmacological Interventions

Sudano, I., Spieker, L. E., Hermann, F., Flammer, A. J., Corti, R., Noll, G., & scher, T. F. L. (2006) · Journal of Cardiovascular Pharmacology · doi:10.1097/00005344-200606001-00008 · Cited by 65

The inflammatory process in aging

Yu, B. P., & Chung, H. Y. (2006) · Reviews in Clinical Gerontology · doi:10.1017/s0959259807002110 · Cited by 65

Macrolide Antibiotics Protect Against Immune Complex-Induced Lung Injury in Rats: Role of Nitric Oxide from Alveolar Macrophages

Tamaoki, J., Kondo, M., Kohri, K., Aoshiba, K., Tagaya, E., & Nagai, A. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.163.5.2909 · Cited by 65

Generation of Oxygen Radicals and Mechanisms of Injury Prevention

Castranova, V. (1994) · Environmental Health Perspectives · doi:10.1289/ehp.94102s1065 · Cited by 65

Effect of NO Donors on LV Diastolic Function in Patients With Severe Pressure-Overload Hypertrophy

Matter, C. M., Mandinov, L., Kaufmann, P. A., Vassalli, G., Jiang, Z., & Hess, O. M. (1999) · Circulation · doi:10.1161/01.cir.99.18.2396 · Cited by 65

Modulation of mitochondrial respiration by nitric oxide: investigation by single cell fluorescence microscopy

Sarti, P., Lendaro, E., Ippoliti, R., Bellelli, A., Benedetti, P. A., & Brunori, M. (1999) · The FASEB Journal · doi:10.1096/fasebj.13.1.191 · Cited by 65

Nitric Oxide and Reactive Nitrogen Oxide Species in Plants

Durzan, D. J., & Pedroso, M. C. (2002) · Biotechnology and Genetic Engineering Reviews · doi:10.1080/02648725.2002.10648032 · Cited by 68

Pleiotropic Functions of Glutathione S-Transferase P

Zhang, J., Grek, C. L., Ye, Z., Manevich, Y., Tew, K. D., & Townsend, D. M. (2014) · Advances in cancer research · doi:10.1016/b978-0-12-420117-0.00004-9 · Cited by 65

Inducible Nitric Oxide Synthase Protection Against Coxsackievirus Pancreatitis

Zaragoza, C., Ocampo, C. J., Saura, M., Bao, C., Leppo, M. K., Lafond-Walker, A., Thiemann, D. R., Hruban, R. H., & Lowenstein, C. J. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.163.10.5497 · Cited by 64

Effect of 2-(2-Pyridyl)azole-Based Ancillary Ligands (L1-4) on the Electrophilicity of the Nitrosyl Function in [RuII(trpy)(L1-4)(NO)]3+ [trpy = 2,2‘:6‘,2‘ ‘-Terpyridine]. Synthesis, Structures, and Spectroscopic, Electrochemical, and Kinetic Aspects

Chanda, N., Paul, D., Kar, S., Mobin, S. M., Datta, A., Puranik, V. G., Rao, K. K., & Lahiri, G. K. (2005) · Inorganic Chemistry · doi:10.1021/ic048184w · Cited by 64

Nitric oxide in respiratory diseases

Nevin, B. J., & Broadley, K. J. (2002) · Pharmacology & Therapeutics · doi:10.1016/s0163-7258(02)00262-0 · Cited by 64

Actions of S-nitrosocysteine in the nucleus tractus solitarii are unrelated to release of nitric oxide

Ohta, H., Bates, J. N., Lewis, S. J., & Talman, W. T. (1997) · Brain Research · doi:10.1016/s0006-8993(96)01188-2 · Cited by 64

Tetrahydrobiopterin-deficient nitric oxide synthase has a modified heme environment and forms a cytochrome P 420 analog

Wang, J., Stuehr, D. J., & Rousseau, D. L. (1995) · Biochemistry · doi:10.1021/bi00021a020 · Cited by 64

Inotropic Effects of Glyceryl Trinitrate and Spontaneous NO Donors in the Dog Heart

Preckel, B., Kojda, G., Schlack, W. S., Ebel, D., Kottenberg, K., Noack, E., & Thämer, V. (1997) · Circulation · doi:10.1161/01.cir.96.8.2675 · Cited by 64

Deficiency of Lung Antioxidants in Idiopathic Pulmonary Arterial Hypertension

Masri, F. A., COMHAIR, S. A. A., Dostanic‐Larson, I., Kaneko, F. T., Dweik, R. A., Arroliga, A. C., & ERZURUM, S. C. (2008) · Clinical and Translational Science · doi:10.1111/j.1752-8062.2008.00035.x · Cited by 63

Nitric oxide and peroxynitrite have different antiviral effects against hantavirus replication and free mature virions

Klingström, J., Åkerström, S., Hardestam, J., Stoltz, M., Simon, M., Falk, K. I., Mirazimi, A., Rottenberg, M. E., & Lundkvist, Å. (2006) · European Journal of Immunology · doi:10.1002/eji.200535587 · Cited by 63

New development of the yolk sac theory in diabetic embryopathy: molecular mechanism and link to structural birth defects

Dong, D., Reece, E. A., Lin, X., Wu, Y., AriasVillela, N., & Yang, P. (2015) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2015.09.082 · Cited by 63

The antiviral role of nitric oxide

Mannick, J. B. (1995) · Research in Immunology · doi:10.1016/0923-2494(96)84920-0 · Cited by 64

Cellular Applications of a Sensitive and Selective Fiber-Optic Nitric Oxide Biosensor Based on a Dye-Labeled Heme Domain of Soluble Guanylate Cyclase

Barker, S. L. R., Zhao, Y., Marletta, M. A., & Kopelman, R. (1999) · Analytical Chemistry · doi:10.1021/ac9901081 · Cited by 63

Developmental differences determine larval susceptibility to nitric oxide-mediated killing in a murine model of vaccination against Schistosoma mansoni

Ahmed, S. F., Oswald, I. P., Caspar, P., Hieny, S. E., Keefer, L. K., Sher, A., & James, S. L. (1997) · Infection and Immunity · doi:10.1128/iai.65.1.219-226.1997 · Cited by 63

Age‐Related Decline in Murine Macrophage Production of Nitric Oxide

Kissin, E. Y., Tomasi, M., McCartney-Francis, N. L., Gibbs, C. L., & Smith, P. D. (1997) · The Journal of Infectious Diseases · doi:10.1086/513959 · Cited by 63

Impact of Inhaled Nitric Oxide on Platelet Aggregation and Fibrinolysis in Rats with Endotoxic Lung Injury: Role of Cyclic Guanosine 5 ′ -monophosphate

Kermarrec, N., Zunic, P., Béloucif, S., Bénessiano, J., Drouet, L. O., & Payen, D. M. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.158.3.9709097 · Cited by 63

N−NO Bond Dissociation Energies of N-Nitroso Diphenylamine Derivatives (Or Analogues) and Their Radical Anions: Implications for the Effect of Reductive Electron Transfer on N−NO Bond Activation and for the Mechanisms of NO Transfer to Nitranions

Zhu, X., He, J., Li, Q., Xian, M., Lü, J., & Cheng, J. (2000) · The Journal of Organic Chemistry · doi:10.1021/jo000865v · Cited by 63

Chapter 6 Redox modulation of the NMDA receptor by NO-related species

Lipton, S. A., Rayudu, P. V., Choi, Y., Sucher, N. J., & Chen, H.-S. V. (1998) · Progress in brain research · doi:10.1016/s0079-6123(08)63201-x · Cited by 63

Signal transduction by protein tyrosine nitration: competition or cooperation with tyrosine phosphorylation-dependent signaling events?

Monteiro, H. P. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)00893-6 · Cited by 63

Basic fibroblast growth factor protects cardiac myocytes from iNOS‐mediated apoptosis

Iwai‐Kanai, E., Hasegawa, K., Fujita, M., Araki, M., Yanazume, T., Adachi, S., & Sasayama, S. (2001) · Journal of Cellular Physiology · doi:10.1002/jcp.10036 · Cited by 63

Inactivation of Brain Tryptophan Hydroxylase by Nitric Oxide

Kuhn, D. M., & Arthur, R. E. (1996) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1996.67031072.x · Cited by 63

Electron paramagnetic resonance spectroscopy with N-methyl-D-glucamine dithiocarbamate iron complexes distinguishes nitric oxide and nitroxyl anion in a redox-dependent manner: applications in identifying nitrogen monoxide products from nitric oxide synthase

Xia, Y., Cardounel, A. J., Vanin, A. F., & Zweier, J. L. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00427-5 · Cited by 63

Increased Cytotoxicity of 3-Morpholinosydnonimine to HepG2 Cells in the Presence of Superoxide Dismutase

Gergèl, D., Mišı́k, V., Ondriaš, K., & Cederbaum, A. I. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.36.20922 · Cited by 63

An enzyme that selectively S-nitrosylates proteins to regulate insulin signaling

Zhou, H., Grimmett, Z. W., Venetos, N. M., Stomberski, C. T., Qian, Z., McLaughlin, P. J., Bansal, P. K., Zhang, R., Reynolds, J. D. H., Premont, R. T., et al. (2023) · Cell · doi:10.1016/j.cell.2023.11.009 · Cited by 63

Action and target sites of nitric oxide in chloroplasts

Misra, A. N., Vladkova, R. S., Singh, R. K., Misra, M., Dobrikova, A. G., & Apostolova, E. (2014) · Nitric Oxide · doi:10.1016/j.niox.2014.04.003 · Cited by 62

Aerobic Oxidative Iodination of Organic Compounds with Iodide Catalyzed by Sodium Nitrite

Stavber, G., Iskra, J., Zupan, M., & Stavber, S. (2008) · Advanced Synthesis & Catalysis · doi:10.1002/adsc.200800553 · Cited by 62

Effect of selenium on pancreatic proinflammatory cytokines in streptozotocin-induced diabetic mice

Zeng, J., Zhou, J., & Huang, K. (2008) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2008.05.012 · Cited by 62

Molecular Mechanism of the Inactivation of Tryptophan Hydroxylase by Nitric Oxide: Attack on Critical Sulfhydryls that Spare the Enzyme Iron Center

Kuhn, D. M., & Arthur, R. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-19-07245.1997 · Cited by 62

Photo-induced nitric oxide release from chlorobis(2,2′-bipyridine)nitrosylruthenium(II) in aqueous solution

Togniolo, V., da Silva, R. S., & Tedesco, A. C. (2001) · Inorganica Chimica Acta · doi:10.1016/s0020-1693(01)00370-x · Cited by 62

Up-regulation of inducible nitric oxide synthase in Helicobacter pylori-associated gastritis may represent an increased risk factor to develop gastric carcinoma of the intestinal type

Rieder, G., Hofmann, J. A., Hatz, R. A., Stolte, M., & Enders, G. A. (2003) · International Journal of Medical Microbiology · doi:10.1078/1438-4221-00280 · Cited by 62

Inhibitory Action of Nitric Oxide on Circulating Tumor Necrosis Factor-Induced NF-κB Activity and COX-2 Transcription in the Endothelium of the Brain Capillaries

Blais, V., & Rivest, S. (2001) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/60.9.893 · Cited by 63

Measurement of nitrite and nitrate levels in biological samples by capillary electrophoresis

Meulemans, A., & Delsenne, F. (1994) · Journal of Chromatography B Biomedical Sciences and Applications · doi:10.1016/0378-4347(94)00310-6 · Cited by 62

Alterations in the redox state and liver damage: Hints from the EASL Basic School of Hepatology

Tell, G., Vascotto, C., & Tiribelli, C. (2012) · Journal of Hepatology · doi:10.1016/j.jhep.2012.09.018 · Cited by 61

Characterization of a cellular denitrase activity that reverses nitration of cyclooxygenase

Deeb, R. S., Nuriel, T., Cheung, C., Summers, B. D., Lamon, B. D., Gross, S. S., & Hajjar, D. P. (2013) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00876.2012 · Cited by 64

Lymphocyte Development Requires S-nitrosoglutathione Reductase

Yang, Z., Wang, Z., Doulias, P., Wei, W., Ischiropoulos, H., Locksley, R. M., & Liu, L. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1000080 · Cited by 62

Induction of heme oxygenase-1 as a response in sensing the signals evoked by distinct nitric oxide donors

Hara, E., Takahashi, K., Takeda, K., Nakayama, M., Yoshizawa, M., Fujita, H., Shirato, K., & Shibahara, S. (1999) · Biochemical Pharmacology · doi:10.1016/s0006-2952(99)00097-0 · Cited by 61

Suppressor macrophages in Trypanosoma brucei infection: nitric oxide is related to both suppressive activity and lifespan in vivo

Mabbott, N. A., Sutherland, I. A., & STERNBERG, J. M. (1995) · Parasite Immunology · doi:10.1111/j.1365-3024.1995.tb01016.x · Cited by 61

Preparation of a Nitroxyl (HNO) Complex of Rhenium by Selective Oxidation of Coordinated Hydroxylamine

Southern, J. S., Hillhouse, G. L., & Rheingold, A. L. (1997) · Journal of the American Chemical Society · doi:10.1021/ja973316o · Cited by 61

Regulation mechanisms of intestinal secretion: implications in nutrient absorption

Wapnir, R. A. (2002) · The Journal of Nutritional Biochemistry · doi:10.1016/s0955-2863(02)00181-x · Cited by 61

Antioxidant Mechanisms of Nitric Oxide Against Iron-Catalyzed Oxidative Stress in Cells

Kagan, V. E., Kozlov, A. V., Tyurina, Y. Y., Shvedova, A. A., & Yalowich, J. C. (2001) · Antioxidants and Redox Signaling · doi:10.1089/152308601300185160 · Cited by 61

Investigations Into the Role of Nitric Oxide and the Large Intracranial Arteries in Migraine Headache

Thomsen, L. (1997) · Cephalalgia · doi:10.1046/j.1468-2982.1997.1708873.x · Cited by 61

Hydrogen peroxide at low concentrations strongly enhances the inhibitory effect of nitric oxide on platelets

Naseem, K. M., & Bruckdorfer, K. R. (1995) · Biochemical Journal · doi:10.1042/bj3100149 · Cited by 61

A possible role for nitric oxide in modulating the functional cyclosporine toxicity by arginine

Amore, A., Gianoglio, B., Ghigo, D., Peruzzi, L., Porcellini, M. G., Bussolino, F., Costamagna, C., Cacace, G., Picciotto, G., Mazzucco, G., et al. (1995) · Kidney International · doi:10.1038/ki.1995.213 · Cited by 61

Modulation of Nitric Oxide-Induced Apoptotic Death of HL-60 Cells by Protein Kinase C and Protein Kinase A through Mitogen-Activated Protein Kinases and CPP32-like Protease Pathways

Jun, C., Pae, H., Kwak, H. J., Yoo, J.-C., Choi, B., Oh, C., Chun, J., Paik, S., Park, Y., & Chung, H. (1999) · Cellular Immunology · doi:10.1006/cimm.1999.1480 · Cited by 61

Neuroprotective Actions of Coenzyme Q10 in Parkinson's Disease

Sharma, S., Kheradpezhou, M., Shavali, S., Refaey, H. E., Eken, J., Hagen, C., & Ebadi, M. (2004) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(04)82027-5 · Cited by 60

N-Methyl-d-aspartate Induces Neurogranin/RC3 Oxidation in Rat Brain Slices

Li, J., Pak, J. H., Huang, F. L., & Huang, K. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.3.1294 · Cited by 60

Targeting the NO/superoxide ratio in adipose tissue: relevance to obesity and diabetes management

Janković, A., Korać, A., Buzadžić, B., Stančić, A., Otašević, V., Ferdinándy, P., Daiber, A., & Korać, B. (2016) · British Journal of Pharmacology · doi:10.1111/bph.13498 · Cited by 60

Curcumin overcomes the inhibitory effect of nitric oxide on Leishmania

Chan, M. M.-Y., Adapala, N. S., & Fong, D. (2005) · Parasitology Research · doi:10.1007/s00436-005-1323-9 · Cited by 60

Molecular mechanisms of nitrosative stress-mediated protein misfolding in neurodegenerative diseases

Nakamura, T., & Lipton, S. A. (2007) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-007-6525-0 · Cited by 60

Nitric Oxide Synthesis Enhances Human Immunodeficiency Virus Replication in Primary Human Macrophages

Blond, D., Raoul, H., Grand, R. L., & Dormont, D. (2000) · Journal of Virology · doi:10.1128/jvi.74.19.8904-8912.2000 · Cited by 60

Detailed methods for the quantification of nitric oxide in aqueous solutions using either an oxygen monitor or EPR

Venkataraman, S., Martin, S. M., Schafer, F. Q., & Buettner, G. R. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00404-4 · Cited by 60

Effect of Late Modulation of Nitric Oxide Production on Murine Lupus

Oates, J. C., Ruiz, P., Alexander, A. A., Pippen, A. M., & Gilkeson, G. S. (1997) · Clinical Immunology and Immunopathology · doi:10.1006/clin.1997.4332 · Cited by 60

Development and Cellular Applications of Fiber Optic Nitric Oxide Sensors Based on a Gold-Adsorbed Fluorophore

Barker, S. L. R., & Kopelman, R. (1998) · Analytical Chemistry · doi:10.1021/ac981016z · Cited by 60

Nitric oxide production duringVibrio choleraeinfection

Janoff, E. N., Hayakawa, H., Taylor, D. N., Fasching, C. E., Kenner, J., Jaimes, E. A., & Raij, L. R. (1997) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.1997.273.5.g1160 · Cited by 60

Heme Oxygenase-1 Is Regulated by Angiotensin II in Rat Vascular Smooth Muscle Cells

Ishizaka, N., & Griendling, K. K. (1997) · Hypertension · doi:10.1161/01.hyp.29.3.790 · Cited by 60

Bcl‐2 prevents nitric oxide‐mediated apoptosis and poly(ADP‐ribose) polymerase cleavage

Mělková, Z., Lee, S. B., Rodrı́guez, D., & Estéban, M. (1997) · FEBS Letters · doi:10.1016/s0014-5793(97)00065-3 · Cited by 60

Oxidative Stress and Cerebral Vascular Tone: The Role of Reactive Oxygen and Nitrogen Species

Salvagno, M., Sterchele, E. D., Zaccarelli, M., Mrakic‐Sposta, S., Welsby, I. J., Balestra, C., & Taccone, F. S. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25053007 · Cited by 59

Parallel evolution of Nitric Oxide signaling: Diversity of synthesis and memory pathways

Moroz, L. L. (2011) · Frontiers in bioscience · doi:10.2741/3837 · Cited by 59

Short-term statin administration in hypercholesterolaemic rabbits resistant to postconditioning: effects on infarct size, endothelial nitric oxide synthase, and nitro-oxidative stress

Andreadou, I., Farmakis, D. T., Prokovas, E., Sigala, F., Ζώγα, Α., Spyridaki, K., Papalois, A. E., Papapetropoulos, A., ANASTASIOU‐NANA, M. I., Kremastinos, D. T., et al. (2012) · Cardiovascular Research · doi:10.1093/cvr/cvs121 · Cited by 60

Nitric oxide regulates swimming in the jellyfish Aglantha digitale

Moroz, L. L., Meech, R. W., Sweedler, J. V., & Mackie, G. O. (2004) · The Journal of Comparative Neurology · doi:10.1002/cne.20023 · Cited by 59

Oxidative heme protein-mediated nitroxyl (HNO) generation

Reisz, J. A., Bechtold, E., & King, S. B. (2010) · Dalton Transactions · doi:10.1039/c000980f · Cited by 59

Nitric Oxide Reduction of Copper(II) Complexes: Spectroscopic Evidence of Copper(II)−Nitrosyl Intermediate

Sarma, M., & Mondal, B. (2011) · Inorganic Chemistry · doi:10.1021/ic1011988 · Cited by 59

An Amphiphilic Fluorescent Probe Designed for Extracellular Visualization of Nitric Oxide Released from Living Cells

Yao, H.-W., Zhu, X., Guo, X., & Wang, H. (2016) · Analytical Chemistry · doi:10.1021/acs.analchem.6b01532 · Cited by 59

The dichotomous role of H2S in cancer cell biology? Déjà vu all over again

Kashfi, K. (2018) · Biochemical Pharmacology · doi:10.1016/j.bcp.2018.01.042 · Cited by 59

Evidence for Nitric Oxide Regulation of Hamster Sperm Hyperactivation

Yeoman, R. R., Jones, W. D., & Rizk, B. (1998) · Journal of Andrology · doi:10.1002/j.1939-4640.1998.tb02470.x · Cited by 59

Neutral {Fe(NO)2}9 Dinitrosyliron Complex (DNIC) [(SC6H4-o-NHCOPh)(Im)Fe(NO)2] (Im = Imidazole): Interconversion among the Anionic/Neutral {Fe(NO)2}9 DNICs and Roussin's Red Ester

Tsai, M.-H., & Liaw, W. (2006) · Inorganic Chemistry · doi:10.1021/ic0608849 · Cited by 59

Mitochondrial and Cellular Heme-Dependent Proteins as Targets for the Bioactive Function of the Heme Oxygenase/Carbon Monoxide System

Desmard, M., Boczkowski, J., Poderoso, J. J., & Motterlini, R. (2007) · Antioxidants and Redox Signaling · doi:10.1089/ars.2007.1803 · Cited by 59

Effect of propolis on human cartilage and chondrocytes

Cardile, V., Panico, A., Gentile, B. C., Borrelli, F., & Russo, A. (2003) · Life Sciences · doi:10.1016/s0024-3205(03)00381-3 · Cited by 59

Regulation of Neurotransmitter Reuptake by Nitric Oxide

PÖÜN, Ş., & Kuhar, M. J. (1994) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1994.tb21816.x · Cited by 59

Expression of Endothelial and Inducible Nitric Oxide Synthases and Nitric Oxide Production in Ovine Placental and Uterine Tissues During Late Pregnancya

Zheng, J. J., Li, Y., Weiss, A., Bird, I. M., & Magness, R. R. (2000) · Placenta · doi:10.1053/plac.1999.0504 · Cited by 59

Exogenous reactive oxygen and nitric oxide alter intracellular oxidant status of skeletal muscle fibres

Murrant, Andrade, & Reid (1999) · Acta Physiologica Scandinavica · doi:10.1046/j.1365-201x.1999.00551.x · Cited by 59

Neuroprotective and Neurodestructive Effects of Nitric Oxide and Redox Congeners

Lipton, S. A., Singel, D. J., & Stamler, J. S. (1994) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1994.tb21826.x · Cited by 59

Endogenous nitric oxide in expired air: Effects of acute exercise in humans

Bauer, J. A., Wald, J. A., Doran, S. D., & Soda, D. M. (1994) · Life Sciences · doi:10.1016/0024-3205(94)00522-2 · Cited by 59

Effect of coenzyme Q10 alone and its combination with metformin on streptozotocin-nicotinamide-induced diabetic nephropathy in rats

Maheshwari, R. A., Balaraman, R., Sen, A., & Seth, A. (2014) · Indian Journal of Pharmacology · doi:10.4103/0253-7613.144924 · Cited by 58

A Kinetic Platform to Determine the Fate of Nitric Oxide in Escherichia coli

Robinson, J. L., & Brynildsen, M. P. (2013) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1003049 · Cited by 58

The Evolution of Nitric Oxide Function: From Reactivity in the Prebiotic Earth to Examples of Biological Roles and Therapeutic Applications

Shepherd, M., Giordano, D., Verde, C., & Poole, R. K. (2022) · Antioxidants · doi:10.3390/antiox11071222 · Cited by 20

Chemical biology of nitric oxide: Regulation and protective and toxic mechanisms

Wink, D. A., Hanbauer, I., Grisham, M. B., Laval, F., Nims, R. W., Laval, J., Cook, J. C., Pacelli, R., Liebmann, J., Krishna, M. C., et al. (1996) · Current topics in cellular regulation · doi:10.1016/s0070-2137(96)80006-9 · Cited by 288

Biochemistry of Nitric Oxide and Peroxynitrite: Sources, Targets and Biological Implications

Aicardo, A., Martinez, D. M., Campolo, N., Bartesaghi, S., & Radí, R. (2016) · Springer eBooks · doi:10.1007/978-3-319-45865-6_5 · Cited by 21

Biochemical targets of nitric oxide-induced toxicity.

Grudziński, I. P. (2003) · PubMed · Cited by 3

The Chemical Properties of Nitric Oxide and Related Nitrogen Oxides

Fukuto, J. M., Cho, J. Y., & Switzer, C. H. (2000) · Elsevier eBooks · doi:10.1016/b978-012370420-7/50003-4 · Cited by 79