The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Non-Darwinian Evolution: Most evolutionary change in proteins may be due to neutral mutations and genetic drift.
Abstract
NonDarwinian evolution of protein and DNA, comparing expectations of evolution models for protein and amino acid changes
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A Mathematical Theory of Natural and Artificial Selection, Part V: Selection and Mutation
Haldane, J. B. S. (1927) · Mathematical Proceedings of the Cambridge Philosophical Society · doi:10.1017/s0305004100015644 · Cited by 1,326
Cited by
Kimura, M. (1980) · Journal of Molecular Evolution · doi:10.1007/bf01731581 · Cited by 29,778
Selforganization of matter and the evolution of biological macromolecules
Eigen, M. (1971) · Die Naturwissenschaften · doi:10.1007/bf00623322 · Cited by 3,788
A principle of natural self-organization: Part A: Emergence of the hypercycle
Eigen, M., & Schuster, P. (1977) · Naturwissenschaften · doi:10.1007/bf00450633 · Cited by 1,752
Slightly Deleterious Mutant Substitutions in Evolution
OHTA, T. (1973) · Nature · doi:10.1038/246096a0 · Cited by 1,104
Domingo, E., Sheldon, J., & Perales, C. (2012) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.05023-11 · Cited by 1,009
Ikemura, T. (1981) · Journal of Molecular Biology · doi:10.1016/0022-2836(81)90363-6 · Cited by 875
Phylogenetic Methods Come of Age: Testing Hypotheses in an Evolutionary Context
Huelsenbeck, J. P., & Rannala, B. (1997) · Science · doi:10.1126/science.276.5310.227 · Cited by 781
Synonymous codon usage in Drosophila melanogaster: Natural selection and translational accuracy
Akashi, H. (1994) · Genetics · doi:10.1093/genetics/136.3.927 · Cited by 742
Longevity Among Hunter‐ Gatherers: A Cross‐Cultural Examination
Gurven, M., & Kaplan, H. (2007) · Population and Development Review · doi:10.1111/j.1728-4457.2007.00171.x · Cited by 670
Bromham, L., & Penny, D. (2003) · Nature Reviews Genetics · doi:10.1038/nrg1020 · Cited by 615
Fitch, W. T. (2010) · doi:10.1017/cbo9780511817779 · Cited by 594
The structure of cytochromec and the rates of molecular evolution
Dickerson, R. E. (1971) · Journal of Molecular Evolution · doi:10.1007/bf01659392 · Cited by 544
Origin and evolution of the genetic code: The universal enigma
Koonin, E. V., & Novozhilov, A. S. (2009) · IUBMB Life · doi:10.1002/iub.146 · Cited by 392
Bayesian molecular clock dating of species divergences in the genomics era
dos Reis, M., Donoghue, P. C. J., & Yang, Z. (2016) · Nature Reviews Genetics · doi:10.1038/nrg.2015.8 · Cited by 339
On the constancy of the evolutionary rate of cistrons
Ohta, T., & Kimura, M. (1971) · Journal of Molecular Evolution · doi:10.1007/bf01659391 · Cited by 322
Synonymous mutations in representative yeast genes are mostly strongly non-neutral
Shen, X., Song, S., Li, C., & Zhang, J. (2022) · Nature · doi:10.1038/s41586-022-04823-w · Cited by 298
Estimating the mutation load in human genomes
Henn, B. M., Botigué, L. R., Bustamante, C. D., Clark, A. G., & Gravel, S. (2015) · Nature Reviews Genetics · doi:10.1038/nrg3931 · Cited by 281
On the role of organized multienzyme systems in cellular metabolism: a general synthesis
Welch, G. R. (1978) · Progress in Biophysics and Molecular Biology · doi:10.1016/0079-6107(78)90019-6 · Cited by 260
Pathogens, polymorphism, and the evolution of sex
Tooby, J. (1982) · Journal of Theoretical Biology · doi:10.1016/0022-5193(82)90358-7 · Cited by 260
Paquin, C., & Adams, J. (1983) · Nature · doi:10.1038/302495a0 · Cited by 239
Conservation and the Genomics of Populations
Allendorf, F. W., Funk, W. C., Aitken, S. N., Byrne, M., Luikart, G., & Antunes, A. (2022) · doi:10.1093/oso/9780198856566.001.0001 · Cited by 207
On the rate of molecular evolution
Kimura, M., & Ohta, T. (1971) · Journal of Molecular Evolution · doi:10.1007/bf01659390 · Cited by 195
Higgs, P. G. (2009) · Biology Direct · doi:10.1186/1745-6150-4-16 · Cited by 137
Mineral surface chemistry control for origin of prebiotic peptides
Erastova, V., Degiacomi, M. T., G. Fraser, D., & Greenwell, H. C. (2017) · Nature Communications · doi:10.1038/s41467-017-02248-y · Cited by 145
Neel, J. V. (1970) · Science · doi:10.1126/science.170.3960.815 · Cited by 131
Novozhilov, A. S., Wolf, Y. I., & Koonin, E. V. (2007) · Biology Direct · doi:10.1186/1745-6150-2-24 · Cited by 122
Island songbirds as windows into evolution in small populations
Leroy, T., Rousselle, M., Tilak, M.-K., Caizergues, A. E., Scornavacca, C., Recuerda, M., Fuchs, J., Illera, J. C., De Swardt, D. H., Blanco, G., et al. (2021) · Current Biology · doi:10.1016/j.cub.2020.12.040 · Cited by 113
Elements of an inclusive evolutionary model for archaeology
Leonard, R. D., & Jones, G. T. (1987) · Journal of Anthropological Archaeology · doi:10.1016/0278-4165(87)90001-8 · Cited by 112
Smith, H. F. (2011) · International Journal of Evolutionary Biology · doi:10.4061/2011/145262 · Cited by 68
On the optimality of the genetic code, with the consideration of termination codons
Goodarzi, H., Nejad, H. A., & Torabi, N. (2004) · Biosystems · doi:10.1016/j.biosystems.2004.05.031 · Cited by 55
Lack of Self-Averaging in Neutral Evolution of Proteins
Bastolla, U., Porto, M., Roman, H. E., & Vendruscolo, M. (2002) · Physical Review Letters · doi:10.1103/physrevlett.89.208101 · Cited by 35
Molecular evolution of the oxytocin–oxytocin receptor system in eutherians
Yamashita, K., & Kitano, T. (2013) · Molecular Phylogenetics and Evolution · doi:10.1016/j.ympev.2013.02.017 · Cited by 33
An evolutionary process without variation and selection
Gabora, L., & Steel, M. (2021) · Journal of The Royal Society Interface · doi:10.1098/rsif.2021.0334 · Cited by 23
Deep mutational scanning quantifies DNA binding and predicts clinical outcomes of PAX6 variants
McDonnell, A. F., Plech, M., Livesey, B. J., Gerasimavicius, L., Owen, L. J., Hall, H. N., FitzPatrick, D. R., Marsh, J. A., & Kudla, G. (2024) · Molecular Systems Biology · doi:10.1038/s44320-024-00043-8 · Cited by 16
Interpreting noncoding genetic variation in complex traits and human disease
Ward, L. D., & Kellis, M. (2012) · Nature Biotechnology · doi:10.1038/nbt.2422 · Cited by 6
Metadata
- Authors
- King, J. L., & Jukes, T. H.
- Venue
- Science
- Published
- 1969-05-16
- Volume
- 164
- Issue
- 3881
- Pages
- 788-798
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1983519005
- Cited by
- 1,768
- References
- 1
- FWCI
- 69.12
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
