Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

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2. Intratumoral CD4+ T Cells Mediate Anti-tumor Cytotoxicity in Human Bladder Cancer
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3. Patient-derived xenografts undergo mouse-specific tumor evolution
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4. Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing
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5. Discovery of a periosteal stem cell mediating intramembranous bone formation
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6. Non-genetic mechanisms of therapeutic resistance in cancer
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7. Cells of the human intestinal tract mapped across space and time
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8. A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex
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9. Systematic assessment of tissue dissociation and storage biases in single-cell and single-nucleus RNA-seq workflows
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10. Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma
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11. Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes
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12. Interrogating open issues in cancer precision medicine with patient-derived xenografts
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13. Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours
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14. Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment
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15. Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma
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16. Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro
    2021
17. histoCAT: analysis of cell phenotypes and interactions in multiplex image cytometry data
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18. Cancer SLC43A2 alters T cell methionine metabolism and histone methylation
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19. TGF-β-associated extracellular matrix genes link cancer-associated fibroblasts to immune evasion and immunotherapy failure
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20. The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation
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21. The Human Cell Atlas: from vision to reality
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22. Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1-CD8+ Tumor-Infiltrating T Cells
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23. Single-cell RNA sequencing for the study of development, physiology and disease
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24. Revealing the vectors of cellular identity with single-cell genomics
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25. RNA sequencing: new technologies and applications in cancer research
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26. Cell type and gene expression deconvolution with BayesPrism enables Bayesian integrative analysis across bulk and single-cell RNA sequencing in oncology
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27. Comparative Analysis and Refinement of Human PSC-Derived Kidney Organoid Differentiation with Single-Cell Transcriptomics
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28. The Tumor Microenvironment in the Response to Immune Checkpoint Blockade Therapies
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29. Single-cell transcriptomic architecture and intercellular crosstalk of human intrahepatic cholangiocarcinoma
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30. Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy
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31. Single-cell landscape of immunological responses in patients with COVID-19
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32. Tumour heterogeneity and metastasis at single-cell resolution
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33. From bulk, single-cell to spatial RNA sequencing
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34. Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity
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35. T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation
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36. Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids
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37. Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer
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40. Profiling Cell Type Abundance and Expression in Bulk Tissues with CIBERSORTx
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41. The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution
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42. Dynamics and specificities of T cells in cancer immunotherapy
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43. Single-Cell RNA-Seq Analysis Maps Development of Human Germline Cells and Gonadal Niche Interactions
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44. Hallmarks of transcriptional intratumour heterogeneity across a thousand tumours
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45. Neuroblastoma is composed of two super-enhancer-associated differentiation states
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46. Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer’s disease model
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48. Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer
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52. Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade
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56. Human oral mucosa cell atlas reveals a stromal-neutrophil axis regulating tissue immunity
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58. Tissue-resident memory features are linked to the magnitude of cytotoxic T cell responses in human lung cancer
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61. Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds
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62. A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
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63. Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data
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64. Implementing Genome-Driven Oncology
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66. The Need for Multi-Omics Biomarker Signatures in Precision Medicine
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67. A single-cell landscape of high-grade serous ovarian cancer
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68. CD8+ T Cell Exhaustion in Cancer
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69. Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance
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70. Transcription Factor IRF4 Promotes CD8+ T Cell Exhaustion and Limits the Development of Memory-like T Cells during Chronic Infection
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71. Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression
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72. Fibroblast-macrophage reciprocal interactions in health, fibrosis, and cancer
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73. Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma
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74. Developmental diversification of cortical inhibitory interneurons
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75. Transcriptome Landscape of Human Folliculogenesis Reveals Oocyte and Granulosa Cell Interactions
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76. Dissecting the Single-Cell Transcriptome Network Underlying Gastric Premalignant Lesions and Early Gastric Cancer
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77. Single-Cell RNA Sequencing in Cancer: Lessons Learned and Emerging Challenges
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78. Unravelling subclonal heterogeneity and aggressive disease states in TNBC through single-cell RNA-seq
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79. The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis
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80. Single-cell analysis of human adipose tissue identifies depot- and disease-specific cell types
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81. Single-cell RNA sequencing reveals functional heterogeneity of glioma-associated brain macrophages
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82. Systems Biology of Cancer Metastasis
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83. Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma
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84. Spatial transcriptomics of dorsal root ganglia identifies molecular signatures of human nociceptors
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85. Single-Cell Transcriptome Analysis Maps the Developmental Track of the Human Heart
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86. A clinically applicable integrative molecular classification of meningiomas
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87. Single-cell roadmap of human gonadal development
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88. Single-cell analysis reveals new evolutionary complexity in uveal melanoma
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89. Tubuloids derived from human adult kidney and urine for personalized disease modeling
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90. Immune suppressive landscape in the human esophageal squamous cell carcinoma microenvironment
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91. Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes
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92. The present and future of the Cancer Dependency Map
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93. Single-cell multiomics: multiple measurements from single cells
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94. Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers
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96. Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity
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97. Cancer-associated fibroblast classification in single-cell and spatial proteomics data
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98. Droplet-based combinatorial indexing for massive-scale single-cell chromatin accessibility
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99. Induction and transcriptional regulation of the co-inhibitory gene module in T cells
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100. Cell type transcriptome atlas for the planarian Schmidtea mediterranea
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