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Transmission of SARS-CoV-2 on mink farms between humans and mink and back to humans
Open accessPublished version of a preprint
Abstract
Two-way transmission on mink farms: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a zoonotic virus—one that spilled over from another species to infect and transmit among humans. We know that humans can infect other animals with SARS-CoV-2, such as domestic cats and even tigers in zoos. Oude Munnink et al. used whole-genome sequencing to show that SARS-CoV-2 infections were rife among mink farms in the southeastern Netherlands, all of which are destined to be closed by March 2021 (see the Perspective by Zhou and Shi). Toward the end of June 2020, 68% of mink farm workers tested positive for the virus or had antibodies to SARS-CoV-2. These large clusters of infection were initiated by human COVID-19 cases with viruses that bear the D614G mutation. Sequencing has subsequently shown that mink-to-human transmission also occurred. More work must be done to understand whether there is a risk that mustelids may become a reservoir for SARS-CoV-2. Science , this issue p. 172 ; see also p. 120
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Metadata
- Authors
- Oude Munnink, B. B., Sikkema, R. S., Nieuwenhuijse, D. F., Molenaar, R. J., Munger, E., Molenkamp, R., van der Spek, A., Tolsma, P., Rietveld, A., Brouwer, M., Bouwmeester-Vincken, N., Harders, F., Hakze-van der Honing, R., Wegdam-Blans, M. C. A., Bouwstra, R. J., GeurtsvanKessel, C., van der Eijk, A. A., Velkers, F. C., Smit, L. A. M., Stegeman, A., van der Poel, W. H. M., & Koopmans, M. P. G.
- Venue
- Science
- Published
- 2021-01-08
- Volume
- 371
- Issue
- 6525
- Pages
- 172-177
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W3102258632
- Cited by
- 1,117
- References
- 54
- FWCI
- 27.40
- Type
- journal article
- Language
- en
- Open access
- hybrid
- Funders
- ZonMW (10150062010005)
- European Union’s Horizon 2020 research and innovation programme (848096, 101003589)
- The European Union’s Horizon 2020 research and innovation programme (874735)
- the Netherlands Ministry of Agriculture, Nature and Foods
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