Cited by 3,039Influenza Virus Research StudiesData-Driven Disease SurveillanceResearch Data Management Practices

GISAID: Global initiative on sharing all influenza data – from vision to reality

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Shu, Yuelong, McCauley, John·2017·Eurosurveillance

Abstract

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  • Passive transfer of purified polyclonal IgGs from convalescent macaques protected naïve macaques against subsequent SARS-CoV-2 challenge.

    “Moreover, passive transfer of purified polyclonal IgGs from convalescent macaques protected naïve macaques against subsequent SARS-CoV-2 challenge39.”
  • Out of the 19 RBM-specific mAbs that showed reduced or loss of neutralization of the TM mutant, 16 showed complete or partial loss of binding to the E484K RBD mutant, consistent with E484K being an important viral escape mutation.

    “Out of the 19 RBM-specific mAbs that showed reduced or loss of neutralization of TM mutant (Fig. 4d), 16 showed a complete or partial loss of binding to E484K RBD mutant (Fig. 4g-h), consistent with findings that E484K is an important viral escape mutation26, 39, 27.”
  • Approximately 10% of B.1.1.529 viruses in GISAID contain R346K.

    “Approximately 10% of the B.1.1.529viruses in the Global Initiative on Sharing All Influenza Data (GISAID) 1 also contain an additional RBD mutation, R346K”

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Authors
Shu, Y., & McCauley, J.
Affiliations
  • Chinese Center For Disease Control and Prevention (CN)
  • The Francis Crick Institute (GB)
Venue
Eurosurveillance
Published
2017-03-30
Volume
22
Issue
13
ISSN
  • 1025-496X (ISSN-L)
  • 1560-7917
OpenAlex
W2605343262
Cited by
3,039
References
21
Citations by year
2026: 185 · 2025: 277 · 2024: 303 · 2023: 393 · 2022: 632 · 2021: 748 · 2020: 388 · 2019: 55 · 2018: 32 · 2017: 10 · 2016: 4 · 2015: 1 · 2014: 2 · 2013: 2 · 2012: 1
FWCI
104.34
Type
journal article
Language
en
Open access
Locations
  • Eurosurveillance (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Figshare (submittedVersion, cc-by)
  • The Francis Crick Institute (cc-by)
  • Greater South Information System
Funders
  • Wellcome Trust (FC001030)
  • Cancer Research UK
  • Medical Research Council
Topics
  • Health Sciences › Medicine › Epidemiology › Influenza Virus Research Studies
  • Health Sciences › Medicine › Epidemiology › Data-Driven Disease Surveillance
  • Physical Sciences › Computer Science › Information Systems › Research Data Management Practices
Keywords
GISAID, influenza surveillance, pandemic influenza preparedness
MeSH terms
Cooperative Behavior, Data Collection, Emergencies, Humans, Influenza, Human, Global Health, World Health Organization, Sentinel Surveillance, Information Dissemination, Public Health Informatics

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