The DOI matches its Crossref record; 50 of the 51 references it cites were found in a registry or an index.
Disruption of the Sleep-Wake Cycle and Diurnal Fluctuation of β-Amyloid in Mice with Alzheimer’s Disease Pathology
Open accessAbstract
Decreased sleep and attenuation of circadian fluctuations in Aβ reflect amyloid-associated pathology in Alzheimer’s disease.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“SD is associated with fluctuations in CSF Aβ, as well as Aβ deposition in the brain [567].”
From Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer’s disease (2020) · cites this paper as [567]
In the citing paper
“However, after Aβ plaque formation, there is an impaired sleep-wake cycle and loss of diurnal fluctuation in ISF/CSF Aβ levels (Roh et al., 2012).”
From Alzheimer Disease: An Update on Pathobiology and Treatment Strategies (2019) · cites this paper as Roh et al., 2012
In the citing paper
“In mice overexpressing Aβ, sleep-wake cycle and diurnal fluctuations in ISF and CSF Aβ levels are normal before an age when animals develop amyloid plaque formation.”
From Alzheimer Disease: An Update on Pathobiology and Treatment Strategies (2019) · cites this paper as Roh et al., 2012
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
McKhann, G. M., Knopman, D. S., Chertkow, H., Hyman, B. T., Jack, C. R., Kawas, C. H., Klunk, W. E., Koroshetz, W. J., Manly, J. J., Mayeux, R., et al. (2011) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2011.03.005 · Cited by 18,657
The Mouse Brain in Stereotaxic Coordinates
Paxinos, G. (2001) · Cited by 12,859
Sperling, R. A., Aisen, P. S., Beckett, L. A., Bennett, D. A., Craft, S., Fagan, A. M., Iwatsubo, T., Jack, C. R., Kaye, J., Montine, T. J., et al. (2011) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2011.03.003 · Cited by 7,155
Alzheimer's Disease: Genes, Proteins, and Therapy
Selkoe, D. J. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.2.741 · Cited by 6,063
Diekelmann, S., & Born, J. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2762 · Cited by 3,760
Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse
Schenk, D., Barbour, R., Dunn, W., Gordon, G., Grajeda, H., Guido, T., Hu, K., Huang, J., Johnson-Wood, K., Khan, K., et al. (1999) · Nature · doi:10.1038/22124 · Cited by 3,160
Pellerin, L., & Magistretti, P. J. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.22.10625 · Cited by 2,927
APP Processing and Synaptic Function
Kamenetz, F., Tomita, T., Hsieh, H., Seabrook, G., Borchelt, D., Iwatsubo, T., Sisodia, S., & Malinow, R. (2003) · Neuron · doi:10.1016/s0896-6273(03)00124-7 · Cited by 1,644
Amyloid-β Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle
Kang, J.-E., Lim, M. M., Bateman, R. J., Lee, J. J., Smyth, L. P., Cirrito, J. R., Fujiki, N., Nishino, S., & Holtzman, D. M. (2009) · Science · doi:10.1126/science.1180962 · Cited by 1,565
Self-citationAlzheimer’s Disease: The Challenge of the Second Century
Holtzman, D. M., Morris, J. C., & Goate, A. M. (2011) · Science Translational Medicine · doi:10.1126/scitranslmed.3002369 · Cited by 1,424
Self-citation
Cited by
Sorted by citations
Items 301–400 of 563
Dual orexin receptor antagonists as promising therapeutics for Alzheimer’s disease
Ragsdale, S. M., Radovich, J. M., Coiduras, I. I., McCall, W. V., Grant, S. C., Lee, C. S., & Wilber, A. A. (2025) · npj Biological Timing and Sleep · doi:10.1038/s44323-025-00025-5 · Cited by 20
Leoutsakos, J., Wise, E. A., Lyketsos, C. G., & Smith, G. S. (2019) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.5203 · Cited by 22
Glutamatergic Neurons of the Paraventricular Nucleus are Critical for the Control of Wakefulness
Liu, Y., Li, Y., Yang, B., Yu, M., Zhang, X., Bi, L., & Xu, H. (2020) · Neuroscience · doi:10.1016/j.neuroscience.2020.08.024 · Cited by 19
Brain rhythm attractor breakdown in Alzheimer’s disease: Functional and pathologic implications
Karageorgiou, E., & Vossel, K. A. (2017) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2017.02.003 · Cited by 21
Liao, F., Zhang, T. J., Mahan, T. E., Jiang, H., & Holtzman, D. M. (2014) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2014.09.005 · Cited by 21
Self-citationSleep experiences during different lifetime periods and in vivo Alzheimer pathologies
Choe, Y. M., Byun, M. S., Yi, D., Lee, J. H., Jeon, S. Y., Sohn, B. K., Kim, Y. K., Shin, S. A., Sohn, C., Lee, Y. J., et al. (2019) · Alzheimer s Research & Therapy · doi:10.1186/s13195-019-0536-6 · Cited by 21
Liu, Y., Chen, L., Huang, S., Zhang, C., Lv, Z., Luo, J., Shang, P., Wang, Y., & Xie, H. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.611432 · Cited by 20
Ahnaou, A., & Drinkenburg, W. H. I. M. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.06.039 · Cited by 24
Muto, V., Koshmanova, E., Ghaemmaghami, P., Jaspar, M., Meyer, C., Elansary, M., Egroo, M. V., Chylinski, D., Berthomier, C., Brandewinder, M., et al. (2020) · SLEEP · doi:10.1093/sleep/zsaa137 · Cited by 26
Spira, A. P., Zipunnikov, V., Raman, R., Choi, J., Di, J., Bai, J., Carlsson, C. M., Mintzer, J. E., Marshall, G. A., Porsteinsson, A. P., et al. (2021) · SLEEP Advances · doi:10.1093/sleepadvances/zpab015 · Cited by 20
High-throughput visual assessment of sleep stages in mice using machine learning
Geuther, B. Q., Chen, M., Galante, R. J., Han, O. Y., Lian, J., George, J., Pack, A. I., & Kumar, V. (2021) · SLEEP · doi:10.1093/sleep/zsab260 · Cited by 20
Wang, C., Chen, J., Xiao, H., Kong, L., Zhao, Y., Yu, T., Li, H., Tian, J., Cui, L., Wen, C.-M., et al. (2022) · Neuroscience Letters · doi:10.1016/j.neulet.2022.136473 · Cited by 20
Rhythms in barriers and fluids: Circadian clock regulation in the aging neurovascular unit
Skapetze, L., Owino, S., Lo, E. H., Arai, K., Merrow, M. W., & Harrington, M. E. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2023.106120 · Cited by 20
Mathematical Model Shows How Sleep May Affect Amyloid-β Fibrillization
Hoore, M., Khailaie, S., Montaseri, G., Mitra, T., & Meyer‐Hermann, M. (2020) · Biophysical Journal · doi:10.1016/j.bpj.2020.07.011 · Cited by 22
Deciphering the Interacting Mechanisms of Circadian Disruption and Alzheimer’s Disease
Uddin, M. S., Sumsuzzman, D. M., Jeandet, P., Behl, T., Rauf, A., Amran, M. S., & Ashraf, G. M. (2021) · Neurochemical Research · doi:10.1007/s11064-021-03325-x · Cited by 23
Hua, J., Zhuang, S., Shen, Y., Tang, X., Sun, H., & Fang, Q. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.727763 · Cited by 21
The Nexus of Aβ, Aging, and Sleep
Gerstner, J. R., Perron, I. J., & Pack, A. I. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3004815 · Cited by 19
Leko, M. B., Perković, M. N., Klepac, N., Štrac, D. Š., Borovečki, F., Pivac, N., Hof, P. R., & Šimić, G. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-190991 · Cited by 19
Zhao, P., You, Y., Wang, Z., Zhou, Y., Chai, G., Yan, G., Jin, Z., Wang, Q., & Sun, H. (2022) · Brain Structure and Function · doi:10.1007/s00429-021-02447-w · Cited by 19
Sleep-Related Changes Prior to Cognitive Dysfunction
Pérez‐Carbonell, L., & Iranzo, Á. (2023) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-023-01258-2 · Cited by 20
Park, S. A., Kang, J.-H., Kang, E., Ki, C., Roh, J. H., Youn, Y. C., Kim, S. Y., & Kim, S. (2015) · Journal of Clinical Neurology · doi:10.3988/jcn.2015.11.2.132 · Cited by 19
Self-citationA ticking clock links metabolic pathways and organ systems function in health and disease
Vinciguerra, M., Tevy, M. F., & Mazzoccoli, G. (2013) · Clinical and Experimental Medicine · doi:10.1007/s10238-013-0235-8 · Cited by 20
Sanchez-Espinosa, M. P., Atienza, M., & Cantero, J. L. (2017) · Scientific Reports · doi:10.1038/s41598-017-08292-4 · Cited by 18
Sleep Behavior and EEG Oscillations in Aged Dp(16)1Yey/+ Mice: A Down Syndrome Model
Levenga, J., Peterson, D. J., Cain, P., & Hoeffer, C. A. (2018) · Neuroscience · doi:10.1016/j.neuroscience.2018.02.009 · Cited by 18
Assessing Neuroprotective Agents for Aβ-Induced Neurotoxicity
Forest, K. H., & Nichols, R. A. (2019) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2019.05.013 · Cited by 19
Rowe, R. K., Schulz, P., He, P., Mannino, G. S., Opp, M. R., & Sierks, M. R. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1436966 · Cited by 18
Lai, V. K. Y., Fung, A. W. T., LAM, L. C. W., & Lee, A. T. C. (2022) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.5783 · Cited by 19
A meta-analysis of the relationship between sleep and β-Amyloid biomarkers in Alzheimer’s disease
Harenbrock, J., Holling, H., Reid, G., & Koychev, I. G. (2023) · Biomarkers in Neuropsychiatry · doi:10.1016/j.bionps.2023.100068 · Cited by 20
Keenan, R. J., Daykin, H. J., Metha, J. A., Cornthwaite‐Duncan, L., Wright, D. K., Clarke, K. M., Oberrauch, S., Brian, M. L., Stephenson, S. E. M., Nowell, C. J., et al. (2023) · British Journal of Pharmacology · doi:10.1111/bph.16212 · Cited by 17
Yi, W. (2020) · Genetics and Molecular Biology · doi:10.1590/1678-4685-gmb-2019-0052 · Cited by 18
Chen, D., Wang, X., Huang, T., & Huang, T. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.794202 · Cited by 20
Homer1a and mGluR1/5 Signaling in Homeostatic Sleep Drive and Output.
Martin, S. C., Monroe, S., & Diering, G. H. (2019) · Europe PMC (PubMed Central) · Cited by 18
Progressive sleep disturbance in various transgenic mouse models of Alzheimer’s disease
Drew, V. J., Wang, C., & Kim, T. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1119810 · Cited by 19
Barone, D. A., & Chokroverty, S. (2016) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2016.10.007 · Cited by 18
Navigatore-Fonzo, L., Castro, A., Pignataro, V., Garraza, M. H., Casais, M., & Anzulovich, A. C. (2017) · Brain Research · doi:10.1016/j.brainres.2017.01.033 · Cited by 16
Zhang, F., Zhong, R., Li, S., Chang, R. C., & Le, W. (2017) · Journal of Neural Transmission · doi:10.1007/s00702-017-1696-9 · Cited by 19
The effect of resistance training on sleep in Chinese older adults: A randomized controlled trial
Li, Z., Li, J., Yu, G., Yu, F., Li, K., & Szanton, S. L. (2020) · Geriatric Nursing · doi:10.1016/j.gerinurse.2020.09.002 · Cited by 16
Brain Stimulation for Improving Sleep and Memory
Malkani, R. G., & Zee, P. C. (2022) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2022.06.013 · Cited by 16
Pathogenesis of Depression in Alzheimer’s Disease
Zhan, Q., Kong, F., Shao, S., Zhang, B., & Huang, S.-M. (2023) · Neurochemical Research · doi:10.1007/s11064-023-04061-0 · Cited by 17
Disturbed Sleep in Preclinical Cognitive Impairment: Cause and Effect?
Mander, B. A. (2013) · SLEEP · doi:10.5665/sleep.2942 · Cited by 17
Advances in pathophysiology and neuroimaging: Implications for sleep and dementia
Ward, S. A., & Pase, M. P. (2019) · Respirology · doi:10.1111/resp.13728 · Cited by 18
Kegyes-Brassai, A. C., Pierson-Bartel, R., Bolla, G., Kamondi, A., & Horvath, A. A. (2024) · GeroScience · doi:10.1007/s11357-024-01357-z · Cited by 15
Cognitive Profiles in Patients with Multi-Infarct Dementia: An Omani Study
Al‐Adawi, S., Braidy, N., Essa, M. M., Al-Azri, F. M., Hussain, S., Al‐Sibani, N., Al-Khabouri, J., Al-Asmi, A. R., & Al-Mashani, A. (2014) · Dementia and Geriatric Cognitive Disorders Extra · doi:10.1159/000363621 · Cited by 15
Shared Patterns of Brain Functional Connectivity for the Comorbidity between Migraine and Insomnia
Chou, K., Kuo, C.-Y., Liang, C., Lee, P., Tsai, C., Tsai, C., Huang, M.-H., Hsu, Y., Lin, G., Lin, Y.-K., et al. (2021) · Biomedicines · doi:10.3390/biomedicines9101420 · Cited by 15
Zhang, F., Niu, L., Zhong, R., Li, S., & Le, W. (2023) · Journal of Alzheimer s Disease · doi:10.3233/jad-221048 · Cited by 16
Lifestyle factors that affect cognitive function–a longitudinal objective analysis
Kimura, N., Sasaki, Y., Masuda, T., Ataka, T., Eguchi, A., Kakuma, T., & Matsubara, E. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1215419 · Cited by 15
TDP-43 impairs sleep in Drosophila through Ataxin-2 –dependent metabolic disturbance
Perlegos, A. E., Durkin, J., Belfer, S. J., Rodriguez, A., Shcherbakova, O., Park, K. H., Luong, N. B. H., Bonini, N. M., & Kayser, M. S. (2024) · Science Advances · doi:10.1126/sciadv.adj4457 · Cited by 14
A Hypnic Hypothesis of Alzheimer's Disease
Clark, C. N., & Warren, J. D. (2013) · Neurodegenerative Diseases · doi:10.1159/000350060 · Cited by 14
Wie Schlaf und Alzheimer-Krankheit zusammenhängen
Busche, M. A., Kekuš, M., & Förstl, H. (2016) · Der Nervenarzt · doi:10.1007/s00115-016-0122-0 · Cited by 17
Keenan, R. J., Oberrauch, S., Bron, R., Nowell, C. J., Challis, L. M., Hoyer, D., & Jacobson, L. H. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-201177 · Cited by 15
Hector, A., Provost, C., Delignat‐Lavaud, B., Bouamira, K., Menaouar, C.-A., Mongrain, V., & Brouillette, J. (2023) · Alzheimer s Research & Therapy · doi:10.1186/s13195-023-01316-4 · Cited by 14
Indirect pharmacodynamic models for responses with circadian removal
Ayyar, V. S., Krzyżański, W., & Jusko, W. J. (2019) · Journal of Pharmacokinetics and Pharmacodynamics · doi:10.1007/s10928-019-09620-z · Cited by 15
Metabolic Disturbances Induced by Sleep Restriction as Potential Triggers for Alzheimer’s Disease
García‐Aviles, J. E., Méndez‐Hernández, R., Guzmán‐Ruiz, M. A., Cruz, M., Guerrero‐Vargas, N. N., Velázquez‐Moctezuma, J., & Hurtado‐Alvarado, G. (2021) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2021.722523 · Cited by 17
The relationship between Alzheimer's‐related brain atrophy patterns and sleep macro‐architecture
Weihs, A., Frenzel, S., Garvert, L., Kühn, A. L., Wittfeld, K., Ewert, R., Fietze, I., Penzel, T., Stubbe, B., Szentkirályi, A., et al. (2022) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1002/dad2.12371 · Cited by 12
Deng, Z., Wang, H., Huang, K., Li, Y., Ran, Y., Chen, Y., & Zhou, L. (2023) · Journal of Neurology · doi:10.1007/s00415-023-11604-6 · Cited by 14
Early signs of neurodegenerative diseases: Possible mechanisms and targets for Golgi stress
Liu, M., Duan, Y., Dong, J., Zhang, K., Jin, X., Gao, M., Jia, H., Chen, J., Liu, M., Wei, M., et al. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116646 · Cited by 14
Impact of Pharmacotherapy on Insomnia in Patients with Alzheimer’s Disease
Roland, J. P., & Bliwise, D. L. (2021) · Drugs & Aging · doi:10.1007/s40266-021-00891-1 · Cited by 14
Keenan, R. J., Daykin, H. J., Chu, J., Cornthwaite‐Duncan, L., Allocca, G., Hoyer, D., & Jacobson, L. H. (2022) · British Journal of Pharmacology · doi:10.1111/bph.15813 · Cited by 13
Kudo, T., Loh, D. H., Tahara, Y., Truong, D. A., Hernández, E., & Colwell, C. S. (2013) · ASN NEURO · doi:10.1042/an20130042 · Cited by 15
Therapeutic implications of circadian clocks in neurodegenerative diseases
Chang, Y. C., & Kim, J. Y. (2019) · Journal of Neuroscience Research · doi:10.1002/jnr.24572 · Cited by 15
Miranda, A. H., Peek, E. M., Ancoli‐Israel, S., Young, J. W., Perry, W., & Minassian, A. (2023) · Behavioral Sleep Medicine · doi:10.1080/15402002.2023.2232497 · Cited by 13
The Hierarchy of Coupled Sleep Oscillations Reverses with Aging in Humans
Züst, M. A., Mikutta, C. A., Omlin, X., DeStefani, T., Wunderlin, M., Zeller, C. J., Fehér, K. D., Hertenstein, E., Schneider, C. L., Teunissen, C. E., et al. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.0586-23.2023 · Cited by 14
Champetier, P., André, C., Rehel, S., Ourry, V., Landeau, B., Mézenge, F., Roquet, D., Vivien, D., Sayette, V. D. L., Chételat, G., et al. (2024) · SLEEP · doi:10.1093/sleep/zsae012 · Cited by 14
Neurodegeneration: Amyloid awakenings
Costandi, M. (2013) · Nature · doi:10.1038/497s19a · Cited by 13
Anti‑aging effect of fullerenol on skin aging through derived stem cells in a mouse model
Li, W., Li, N., Sui, B., & Yang, D. (2017) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2017.5163 · Cited by 13
Ruben, M. D., Hogenesch, J. B., & Smith, D. F. (2019) · Neurologic Clinics · doi:10.1016/j.ncl.2019.03.004 · Cited by 15
Sleep Disturbance: An Early Sign of Alzheimer’s Disease
He, C., Hu, Z., & Jiang, C. (2019) · Neuroscience Bulletin · doi:10.1007/s12264-019-00453-x · Cited by 13
Figueiro, M. G., & Leggett, S. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2021.625698 · Cited by 14
Sharma, A., Moon, E., Kim, G., & Kang, S.-U. (2022) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2021.769142 · Cited by 14
Transcranial Impedance Changes during Sleep: A Rheoencephalography Study
Meghdadi, A. H., Popovic, D. P., Rupp, G., Smith, S., Berka, C., & Verma, A. (2019) · IEEE Journal of Translational Engineering in Health and Medicine · doi:10.1109/jtehm.2019.2898193 · Cited by 14
Kopeć, K., Koziorowski, D., & Szlufik, S. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26157552 · Cited by 15
Furtado, A., Esgalhado, A. J., Duarte, A. C., Costa, A. R., Costa‐Brito, A. R., Carro, E., Ishikawa, H., Schroten, H., Schwerk, C., Gonçalves, I., et al. (2022) · Journal of Neuroscience Research · doi:10.1002/jnr.25164 · Cited by 12
Dietary regulation of peroxisome proliferator-activated receptors in metabolic syndrome
Zou, H., Gong, Y., Ye, H., Yuan, C., Li, T., Zhang, J., & Ren, L. (2023) · Phytomedicine · doi:10.1016/j.phymed.2023.154904 · Cited by 13
Zhai, S., Yin, M., Sun, H., Jiang, X., Liu, Y., Marshall, C., Wu, T., & Xiao, M. (2023) · The FASEB Journal · doi:10.1096/fj.202202040rr · Cited by 12
Makibatake, R., Oda, S., Yagi, Y., & Tatsumi, H. (2023) · Scientific Reports · doi:10.1038/s41598-023-40742-0 · Cited by 12
Özcan, G. G., Lim, S., Canning, T., Tirathdas, L., Donnelly, J., Kundu, T., & Rihel, J. (2024) · iScience · doi:10.1016/j.isci.2024.108870 · Cited by 12
Wang, J., Huffman, D., Ajwad, A. A., McLouth, C. J., Bachstetter, A. D., Kohler, K., Murphy, M. P., O’Hara, B. F., Duncan, M. J., & Sunderam, S. (2024) · SLEEP · doi:10.1093/sleep/zsae078 · Cited by 14
Application of mesenchymal stem cells for neurodegenerative diseases therapy discovery
Trinh, Q. D., Nhu, H., & Pham, D. T. (2024) · Regenerative Therapy · doi:10.1016/j.reth.2024.09.014 · Cited by 13
Astrocytes at the heart of sleep: from genes to network dynamics
Bellier, F. C., Walter, A., Lecoin, L., Chauveau, F., Rouach, N., & Rancillac, A. (2025) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-025-05671-3 · Cited by 13
Recent advances in modeling sleep: from the clinic to society and disease
Abel, J. H., Lecamwasam, K. H., Hilaire, M. A. S., & Klerman, E. B. (2019) · Current Opinion in Physiology · doi:10.1016/j.cophys.2019.12.001 · Cited by 12
Sleepiness in neurological disorders
Dubessy, A., & Arnulf, I. (2023) · Revue Neurologique · doi:10.1016/j.neurol.2023.07.005 · Cited by 12
Zhang, S., & Sehgal, A. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-812536-6.00011-0 · Cited by 12
Pak, K., Kim, J., Kim, K., Kim, S., & Kim, I. J. (2020) · Nuclear Medicine and Molecular Imaging · doi:10.1007/s13139-020-00636-9 · Cited by 12
Thomas, J., Ooms, S. J., Mentink, L. J., Booij, J., Rikkert, M. G. M. O., Overeem, S., Kessels, R. P. C., & Claassen, J. A. H. R. (2020) · Alzheimer s Research & Therapy · doi:10.1186/s13195-020-00668-5 · Cited by 13
Sleep and memory consolidation in aging: A neuroimaging perspective
Hamel, A., Mary, A., & Rauchs, G. (2023) · Revue Neurologique · doi:10.1016/j.neurol.2023.08.003 · Cited by 12
Influence of sleep disruption on protein accumulation in neurodegenerative diseases
Wang, X., Wang, R., & Li, J. (2022) · Ageing and Neurodegenerative Diseases · doi:10.20517/and.2021.10 · Cited by 13
Vicente, M. C., Almeida, M. C., Bícego, K. C., Carrettiero, D. C., & Gargaglioni, L. H. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-180397 · Cited by 12
Glymphatic pathway: An emerging perspective in the pathophysiology of neurodegenerative diseases
Rehman, M. U., Sehar, N., Rasool, I., Aldossari, R. M., Wani, A. B., Rashid, S. M., Wali, A. F., Ali, A., Arafah, A. M., & Khan, A. (2024) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.6104 · Cited by 10
Sleep in Normal Aging, Alzheimer's Disease, and Mild Cognitive Impairment
Gagnon, J., Lafrenière, A., Rauchs, G., Petit, D., & Carrier, J. (2019) · Handbook of behavioral neuroscience · doi:10.1016/b978-0-12-813743-7.00045-1 · Cited by 13
Atayde, A. L., Fischer, C. E., Schweizer, T. A., & Muñoz, D. G. (2022) · Journal of Alzheimer s Disease · doi:10.3233/jad-215276 · Cited by 10
Hypocretin/orexin influences chronic sleep disruption injury in the hippocampus
Nick, H., Fenik, P., Zhu, Y., & Veasey, S. C. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.1025402 · Cited by 10
Altered synaptic glutamate homeostasis contributes to cognitive decline in young APP/PSEN1 mice
Wilcox, J. M., Consoli, D. C., Tienda, A. A., Dixit, S., Buchanan, R. A., May, J. M., Nobis, W. P., & Harrison, F. E. (2021) · Neurobiology of Disease · doi:10.1016/j.nbd.2021.105486 · Cited by 10
Zheng, J., Wu, M., Pang, Y., Liu, Q., Liu, Y., Jin, X., Tang, J., Bao, L., Niu, Y., Zheng, Y., et al. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.173254 · Cited by 9
Sleep inhibition induced by amyloid‐β oligomers is mediated by the cellular prion protein
Gallo, F. D., Bianchi, S., Bertani, I., Messa, M., Colombo, L., Balducci, C., Salmona, M., Imeri, L., & Chiesa, R. (2020) · Journal of Sleep Research · doi:10.1111/jsr.13187 · Cited by 10
Kapadia, A. N., Mirrahimi, A., & Dmytriw, A. A. (2020) · Medical Hypotheses · doi:10.1016/j.mehy.2020.110283 · Cited by 8
Zeydan, B., Lowe, V. J., Tosakulwong, N., Lesnick, T. G., Senjem, M. L., Jack, C. R., Fields, J. A., James, T. T., Gleason, C. E., Dowling, N. M., et al. (2021) · Neuroreport · doi:10.1097/wnr.0000000000001592 · Cited by 9
Sleeping well and staying in rhythm to stave off dementia
Malkani, R. G., & Zee, P. C. (2018) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2018.01.007 · Cited by 9
Liu, W., Ma, R., Sun, C., Xu, Y., Liu, Y., Hu, J., Ma, Y., Wang, D., Wen, D., & Yu, Y. (2023) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2023.101789 · Cited by 8
Zhou, X., Du, K., Mao, T., Wang, N., Zhang, L., Tian, Y., Liu, T., Wang, L., & Wang, X. (2024) · iScience · doi:10.1016/j.isci.2024.111413 · Cited by 8
Turton, S. M., Padgett, S., Jessup, M. T., Johnson, C. E., Buzinova, V. A., Barth, S. E., Köhler, K., Spearman, H. M., Macheda, T., Manauis, E. C., et al. (2025) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2025.167840 · Cited by 7
Metadata
- Authors
- Roh, J. H., Huang, Y., Bero, A. W., Kasten, T., Stewart, F. R., Bateman, R. J., & Holtzman, D. M.
- Affiliations
- Washington University in St. Louis (US)
- Corresponding author
- Holtzman, David M.
- Venue
- Science Translational Medicine
- Published
- 2012-09-05
- Volume
- 4
- Issue
- 150
- Pages
- 150ra122-150ra122
- ISSN
- 1946-6234 (ISSN-L)
- 1946-6242
- PMC
- PMC3654377
- OpenAlex
- W2109053359
- Cited by
- 563
- References
- 51
- Citations by year
- 2026: 25 · 2025: 32 · 2024: 42 · 2023: 44 · 2022: 47 · 2021: 50 · 2020: 56 · 2019: 51 · 2018: 48 · 2017: 54 · 2016: 39 · 2015: 28 · 2014: 24 · 2013: 17 · 2012: 5
- FWCI
- 15.87
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Science Translational Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Aging (R01AG013956, K23AG03094604, P01AG026276-S1, P50AG005681, R37AG013956, AG13956, K23AG030946, P01AG026276)
- National Institute of Neurological Disorders and Stroke (P30NS057105, R01NS065667, P01NS074969)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Keywords
- Alzheimer's disease, amyloid-beta, sleep-wake cycle, daily fluctuations, interstitial fluid, cerebrospinal fluid, APPswe/PS1ΔE9 mice, amyloid plaques, presenilin mutations, active immunization, sleep quality, aging
- MeSH terms
- Alzheimer Disease, Animals, Circadian Rhythm, Disease Models, Animal, Genes, Dominant, Hippocampus, Humans, Immunization, Lactates, Mice, Transgenic, Mutation, Sleep, Time Factors, Wakefulness, Amyloid beta-Peptides, Neostriatum, Extracellular Fluid, Mice, Presenilins
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review