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Orexin Receptor Antagonism: Normalizing Sleep Architecture in Old Age and Disease

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The night’s watch: Exploring how sleep protects against neurodegeneration

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Analyzing and Modeling the Dysfunction of Inhibitory Neurons in Alzheimer’s Disease

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The role of circadian rhythm in choroid plexus functions

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Sleep-Based Interventions in Alzheimer’s Disease: Promising Approaches from Prevention to Treatment along the Disease Trajectory

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Association between Sleep, Alzheimer’s, and Parkinson’s Disease

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Insomnia symptom severity and cognitive performance: Moderating role of APOE genotype

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Locomotor Hyperactivity in the Early-Stage Alzheimer’s Disease-like Pathology of APP/PS1 Mice: Associated with Impaired Polarization of Astrocyte Aquaporin 4

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Linking activity dyshomeostasis and sleep disturbances in Alzheimer disease

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Diurnal oscillation of CSF Aβ and other AD biomarkers

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Progressive age-related changes in sleep and EEG profiles in the PLB1Triple mouse model of Alzheimer’s disease

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Amyloid‐β induces sleep fragmentation that is rescued by fatty acid binding proteins in Drosophila

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Alzheimer’s disease and sleep disorders: A bidirectional relationship

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Chronopathophysiological implications of orexin in sleep disturbances and lifestyle-related disorders

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Moderating effect of APOE ε4 on the relationship between sleep-wake cycle and brain β-amyloid

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Age, Sex Hormones, and Circadian Rhythm Regulate the Expression of Amyloid-Beta Scavengers at the Choroid Plexus

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The microbiota–gut–brain axis in mental and neurodegenerative disorders: opportunities for prevention and intervention

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Relationships between the Circadian System and Alzheimer's Disease-Like Symptoms in Drosophila

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Chronic Fragmentation of the Daily Sleep-Wake Rhythm Increases Amyloid-beta Levels and Neuroinflammation in the 3xTg-AD Mouse Model of Alzheimer’s Disease

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Circadian Rhythm Dysfunction Accelerates Disease Progression in a Mouse Model With Amyotrophic Lateral Sclerosis

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Glymphatic System Dysfunction in Central Nervous System Diseases and Mood Disorders

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Review Paper: Tau Pathology of Alzheimer Disease: Possible Role of Sleep Deprivation

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Self‐Reported Sleep Apnea and Dementia Risk: Findings from the Prevention of Alzheimer's Disease with Vitamin E and Selenium Trial

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Young children with Down syndrome show normal development of circadian rhythms, but poor sleep efficiency: a cross-sectional study across the first 60 months of life

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Reprogramming energetic metabolism in Alzheimer's disease

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Bidirectional relationships between sleep and amyloid-beta in the hippocampus

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Integration of Melatonin Related Redox Homeostasis, Aging, and Circadian Rhythm

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Sleep is bi-directionally modified by amyloid beta oligomers

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Abnormal circadian locomotor rhythms and Per gene expression in six-month-old triple transgenic mice model of Alzheimer’s disease

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Jujuboside A prevents sleep loss-induced disturbance of hippocampal neuronal excitability and memory impairment in young APP/PS1 mice

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Association of sleep with cognition and beta amyloid accumulation in adults with Down syndrome

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Mitochondrial Membrane Potential Influences Amyloid-β Protein Precursor Localization and Amyloid-β Secretion

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The Synergistic Relationship between Alzheimer’s Disease and Sleep Disorders: An Update

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Alzheimer's disease pathogenesis: The role of disturbed sleep in attenuated brain plasticity and neurodegenerative processes

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Human genetics and sleep behavior

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Restoring activity in the thalamic reticular nucleus improves sleep architecture and reduces Aβ accumulation in mice

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Ovarian Cycle Stages Modulate Alzheimer-Related Cognitive and Brain Network Alterations in Female Mice

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Delayed daily activity and reduced NREM slow-wave power in the APPswe/PS1dE9 mouse model of Alzheimer's disease

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The Interaction Between Sleep and Metabolism in Alzheimer’s Disease: Cause or Consequence of Disease?

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Shenzao jiannao oral liquid, an herbal formula, ameliorates cognitive impairments by rescuing neuronal death and triggering endogenous neurogenesis in AD-like mice induced by a combination of Aβ42 and scopolamine

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Mutual Interactions between Brain States and Alzheimer’s Disease Pathology: A Focus on Gamma and Slow Oscillations

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Deep brain stimulation of thalamic nucleus reuniens promotes neuronal and cognitive resilience in an Alzheimer’s disease mouse model

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The Role of Sleep in Cognitive Function: The Value of a Good Night’s Rest

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Transforming Sleep Monitoring: Review of Wearable and Remote Devices Advancing Home Polysomnography and Their Role in Predicting Neurological Disorders

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Sleep architecture changes in the APP23 mouse model manifest at onset of cognitive deficits

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Interactions between sleep disturbances and Alzheimer’s disease on brain function: a preliminary study combining the static and dynamic functional MRI

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Sustained high body temperature exacerbates cognitive function and Alzheimer’s disease-related pathologies

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Cerebrospinal Fluid Biomarkers of Neurodegeneration Are Decreased or Normal in Narcolepsy

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Metabolite Clearance During Wakefulness and Sleep

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Amyloid-β–Induced Changes in Molecular Clock Properties and Cellular Bioenergetics

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Alterations and interactions of subcortical modulatory systems in Alzheimer's disease

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Role of sleep in neurodegeneration: the consensus report of the 5th Think Tank World Sleep Forum

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Type-2-Diabetes Alters CSF but Not Plasma Metabolomic and AD Risk Profiles in Vervet Monkeys

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KATP channels are necessary for glucose-dependent increases in amyloid-β and Alzheimer’s disease–related pathology

Grizzanti, J., Moritz, W. R., Pait, M. C., Stanley, M., Kaye, S. D., Carroll, C. M., Constantino, N. J., Deitelzweig, L. J., Snipes, J. A., Kellar, D., et al. (2023) · JCI Insight · doi:10.1172/jci.insight.162454 · Cited by 32

Optogenetic targeting of astrocytes restores slow brain rhythm function and slows Alzheimer’s disease pathology

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Orexins role in neurodegenerative diseases: From pathogenesis to treatment

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Disrupted neural correlates of anesthesia and sleep reveal early circuit dysfunctions in Alzheimer models

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Manipulations of amyloid precursor protein cleavage disrupt the circadian clock in aging Drosophila

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Pimavanserin, a 5HT2A receptor inverse agonist, rapidly suppresses Aβ production and related pathology in a mouse model of Alzheimer’s disease

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Advance in Plasma AD Core Biomarker Development: Current Findings from Immunomagnetic Reduction-Based SQUID Technology

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Novel method for collecting hippocampal interstitial fluid extracellular vesicles (EV ISF ) reveals sex‐dependent changes in microglial EV proteome in response to Aβ pathology

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Dysregulated clock gene expression and abnormal diurnal regulation of hippocampal inhibitory transmission and spatial memory in amyloid precursor protein transgenic mice

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The past, present, and future of sleep measurement in mild cognitive impairment and early dementia—towards a core outcome set: a scoping review

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A Dichotomous Role for FABP7 in Sleep and Alzheimer’s Disease Pathogenesis: A Hypothesis

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Disruption of hippocampal neuronal circuit function depends upon behavioral state in the APP/PS1 mouse model of Alzheimer’s disease

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The state of brain activity modulates cerebrospinal fluid transport

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Sex and Sleep Disruption as Contributing Factors in Alzheimer’s Disease

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Associations between self-reported sleep characteristics and incident mild cognitive impairment: The Heinz Nixdorf Recall Cohort Study

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Circle(s) of Life: The Circadian Clock from Birth to Death

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Exploring the bi-directional relationship between sleep and beta-amyloid

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Sleep and circadian abnormalities precede cognitive deficits in R521C FUS knockin rats

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