The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
The Gracefully Aging Immune System
Abstract
Strategies are being developed to overcome aging-associated changes in the immune response.
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“Decline in the function of the ageing immune system contributes to the increased incidence of infections and the decreased response to vaccination in older adults (aged at least 65 years).1”
From Targeting the biology of ageing with mTOR inhibitors to improve immune function in older adults: phase 2b and phase 3 randomised trials (2021) · cites this paper as [1]
Citations
Cites
Bendall, S. C., Simonds, E. F., Qiu, P., Amir, E.-A. D., Krutzik, P. O., Finck, R., Bruggner, R. V., Melamed, R., Trejo, A., Ornatsky, O. I., et al. (2011) · Science · doi:10.1126/science.1198704 · Cited by 2,279
Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans
den Braber, I., Mugwagwa, T., Vrisekoop, N., Westera, L., Mögling, R., Bregje de Boer, A., Willems, N., Schrijver, E. H. R., Spierenburg, G., Gaiser, K., et al. (2012) · Immunity · doi:10.1016/j.immuni.2012.02.006 · Cited by 572
Panda, A., Qian, F., Mohanty, S., van Duin, D., Newman, F. K., Zhang, L., Chen, S., Towle, V., Belshe, R. B., Fikrig, E., et al. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0901022 · Cited by 548
Ageing and life-long maintenance of T-cell subsets in the face of latent persistent infections.
Nikolich-Žugich, J. (2008) · Nature reviews. Immunology · doi:10.1038/nri2318 · Cited by 463
B‐cell diversity decreases in old age and is correlated with poor health status
Gibson, K. L., Wu, Y., Barnett, Y., Duggan, O., Vaughan, R., Kondeatis, E., Nilsson, B., Wikby, A., Kipling, D., & Dunn‐Walters, D. K. (2009) · Aging Cell · doi:10.1111/j.1474-9726.2008.00443.x · Cited by 433
Inflammaging as a Major Characteristic of Old People: Can It Be Prevented or Cured?
Franceschi, C. (2008) · Nutrition Reviews · doi:10.1111/j.1753-4887.2007.tb00358.x · Cited by 342
Sasaki, S., Sullivan, M., Narvaez, C. F., Holmes, T. H., Furman, D., Zheng, N.-Y., Nishtala, M., Wrammert, J., Smith, K., James, J. A., et al. (2011) · Journal of Clinical Investigation · doi:10.1172/jci57834 · Cited by 300
Telomerase insufficiency in rheumatoid arthritis
Fujii, H., Shao, L., Colmegna, I., Goronzy, J. J., & Weyand, C. M. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811332106 · Cited by 172
Self-citationvan Duin, D., Allore, H. G., Mohanty, S., Ginter, S., Newman, F. K., Belshe, R. B., Medzhitov, R., & Shaw, A. C. (2007) · The Journal of Infectious Diseases · doi:10.1086/516788 · Cited by 159
Deficiency of the DNA repair enzyme ATM in rheumatoid arthritis.
Shao, L., Fujii, H., Colmegna, I., Oishi, H., Goronzy, J. J., & Weyand, C. M. (2009) · Journal of Experimental Medicine · doi:10.1084/jem.20082251 · Cited by 159
Self-citationVukmanovic-Stejic, M., Agius, E., Booth, N., Dunne, P. J., Lacy, K. E., Reed, J. R., Sobande, T. O., Kissane, S., Salmon, M., Rustin, M. H., et al. (2008) · Journal of Clinical Investigation · doi:10.1172/jci35834 · Cited by 131
Johnson, P. L. F., Yates, A. J., Goronzy, J. J., & Antia, R. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1209283110 · Cited by 94
Self-citationImmune memory and aging: an infinite or finite resource?
Nikolich-Žugich, J., & Rudd, B. D. (2010) · Current Opinion in Immunology · doi:10.1016/j.coi.2010.06.011 · Cited by 58
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Cited by
Sorted by citations
mTOR inhibition improves immune function in the elderly
Mannick, J. B., Del Giudice, G., Lattanzi, M., Valiante, N. M., Praestgaard, J., Huang, B., Lonetto, M. A., Maecker, H. T., Kovarik, J., Carson, S., et al. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3009892 · Cited by 786
NADPH oxidase deficiency underlies dysfunction of aged CD8+ Tregs
Wen, Z., Shimojima, Y., Shirai, T., Li, Y., Ju, J., Yang, Z., Tian, L., Goronzy, J. J., & Weyand, C. M. (2016) · Journal of Clinical Investigation · doi:10.1172/jci84181 · Cited by 146
Self-citationChoi, I. Y., Lee, C., & Longo, V. D. (2017) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2017.01.042 · Cited by 133
Mannick, J. B., Teo, G., Bernardo, P., Quinn, D., Russell, K., Klickstein, L., Marshall, W., & Shergill, S. (2021) · The Lancet Healthy Longevity · doi:10.1016/s2666-7568(21)00062-3 · Cited by 131
Kadambari, S., Klenerman, P., & Pollard, A. J. (2020) · Reviews in Medical Virology · doi:10.1002/rmv.2144 · Cited by 118
Metadata
- Authors
- Boraschi, D., Aguado, M. T., Dutel, C., Goronzy, J., Louis, J., Grubeck-Loebenstein, B., Rappuoli, R., & Del Giudice, G.
- Affiliations
- Institute of Biomedical Technologies, National Research Council, Pisa 56124, Italy.
- Initiative for Vaccine Research, WHO, Geneva 1211-27, Switzerland.
- Fondation Mérieux, Lyon 69002, France.
- Stanford University School of Medicine, Stanford, CA 94305–5166, USA.
- Institute for Biomedical Aging Research, University of Innsbruck, Innsbruck 6020, Austria.
- Novartis Vaccines and Diagnostics, Siena 53100, Italy.
- Venue
- Science Translational Medicine
- Published
- 2013-05-15
- Volume
- 5
- Issue
- 185
- ISSN
- 1946-6234
- 1946-6242
- Cited by
- 113
- References
- 13
- Language
- en
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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