NAD + repletion improves muscle function in muscular dystrophy and counters global PARylation

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Subramanian, A., Tamayo, P., Mootha, V. K., Mukherjee, S., Ebert, B. L., Gillette, M. A., Paulovich, A., Pomeroy, S. L., Golub, T. R., Lander, E. S., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506580102 · Cited by 53,625

Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α

Lagouge, M., Argmann, C., Gerhart-Hines, Z., Meziane, H., Lerin, C., Daussin, F., Messadeq, N., Milne, J., Lambert, P., Elliott, P., et al. (2006) · Cell · doi:10.1016/j.cell.2006.11.013 · Cited by 4,057

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy · doi:10.4161/auto.19496 · Cited by 3,996

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

Brunet, A., Sweeney, L. B., Sturgill, J. F., Chua, K. F., Greer, P. L., Lin, Y., Tran, H., Ross, S. E., Mostoslavsky, R., Cohen, H. Y., et al. (2004) · Science · doi:10.1126/science.1094637 · Cited by 3,239

Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase

Yeung, F., Hoberg, J. E., Ramsey, C. S., Keller, M. D., Jones, D. R., Frye, R. A., & Mayo, M. W. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600244 · Cited by 2,750

Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis

Joe, A. W. B., Yi, L., Natarajan, A., Le Grand, F., So, L., Wang, J., Rudnicki, M. A., & Rossi, F. M. V. (2010) · Nature Cell Biology · doi:10.1038/ncb2015 · Cited by 1,690

NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

Cantó, C., Menzies, K. J., & Auwerx, J. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.05.023 · Cited by 1,648

Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging

Gomes, A. P., Price, N. L., Ling, A. J. Y., Moslehi, J. J., Montgomery, M. K., Rajman, L., White, J. P., Teodoro, J. S., Wrann, C. D., Hubbard, B. P., et al. (2013) · Cell · doi:10.1016/j.cell.2013.11.037 · Cited by 1,482

Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice

Yoshino, J., Mills, K. F., Yoon, M. J., & Imai, S.-I. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.08.014 · Cited by 1,340

Cellular and molecular mechanisms of muscle atrophy

Bonaldo, P., & Sandri, M. (2013) · Disease Models & Mechanisms · doi:10.1242/dmm.010389 · Cited by 1,284

Photosynthetic Cyanobacteria can Clearly Induce Efficient Muscle Tissue Regeneration of Bioprinted Cell‐Constructs

Hwangbo, H., Lee, H., Jin, E., Jo, Y., Son, J., Woo, H. M., Ryu, D., & Kim, G. (2022) · Advanced Functional Materials · doi:10.1002/adfm.202209157 · Cited by 39

Skeletal muscle enhancer interactions identify genes controlling whole-body metabolism

Williams, K., Ingerslev, L. R., Bork‐Jensen, J., Wohlwend, M., Hansen, A. N., Small, L., Ribel‐Madsen, R., Astrup, A. V., Pedersen, O. B., Auwerx, J. H., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-16537-6 · Cited by 40

Maintenance of NAD+ Homeostasis in Skeletal Muscle during Aging and Exercise

Ji, L. L., & Yeo, D. (2022) · Cells · doi:10.3390/cells11040710 · Cited by 44

Mitochondrial function in liver cells is resistant to perturbations in NAD+ salvage capacity

Dall, M., Trammell, S. A. J., Asping, M., Hassing, A. S., Agerholm, M., Vienberg, S. G., Gillum, M. P., Larsen, S., & Treebak, J. T. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.ra118.006756 · Cited by 40

NAD+ centric mechanisms and molecular determinants of skeletal muscle disease and aging

Wagner, S., Manickam, R., Brotto, M. A. P., & Tipparaju, S. M. (2022) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-022-04408-1 · Cited by 39

The role of caloric load and mitochondrial homeostasis in the regulation of the NLRP3 inflammasome

Traba, J., & Sack, M. N. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2431-7 · Cited by 37

Role of PGC-1α in the Mitochondrial NAD+ Pool in Metabolic Diseases

Koh, J., & Kim, J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22094558 · Cited by 39

Physiological Systems in Promoting Frailty

Perazza, L. R., Brown‐Borg, H. M., & Thompson, L. V. (2022) · Comprehensive physiology · doi:10.1002/cphy.c210034 · Cited by 69

Current Uncertainties and Future Challenges Regarding NAD+ Boosting Strategies

Poljšak, B., Kovač, V., & Milisav, I. (2022) · Antioxidants · doi:10.3390/antiox11091637 · Cited by 42

High Dose of Dietary Nicotinamide Riboside Induces Glucose Intolerance and White Adipose Tissue Dysfunction in Mice Fed a Mildly Obesogenic Diet

Shi, W., Hegeman, M. A., Doncheva, A. I., Bekkenkamp‐Grovenstein, M., de Boer, V. C. J., & Keijer, J. (2019) · Nutrients · doi:10.3390/nu11102439 · Cited by 37

Pyridine Dinucleotides from Molecules to Man

Fessel, J. P., & Oldham, W. M. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7120 · Cited by 35

Nicotinamide protects against skeletal muscle atrophy in streptozotocin-induced diabetic mice

Guo, S., Chen, Q., Sun, Y., & Chen, J. (2019) · Archives of Physiology and Biochemistry · doi:10.1080/13813455.2019.1638414 · Cited by 37

Psat1-generated α-ketoglutarate and glutamine promote muscle stem cell activation and regenerationPreprint

Ciuffoli, V., Feng, X., Jiang, K., Acevedo-Luna, N., Ko, K. D., Wang, A. H. J., Riparini, G., Khateb, M., Glancy, B. C., Dell’Orso, S., et al. (2024) · Genes & Development · doi:10.1101/gad.351428.123 · Cited by 38

Epithelial NAD+ depletion drives mitochondrial dysfunction and contributes to intestinal inflammation

Novak, E. A., Crawford, E. C., Mentrup, H. L., Griffith, B. D., Fletcher, D. M., Flanagan, M. R., Schneider, C., Firek, B., Rogers, M. B., Morowitz, M. J., et al. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1231700 · Cited by 34

NAD+ precursor increases aerobic performance in mice

Crisol, B., Veiga, C. B., Braga, R. R., Lenhare, L., Baptista, I. L., Gaspar, R. C., Muñoz, V. R., Cordeiro, A. V., da Silva, A. S. R., Cintra, D. E., et al. (2019) · European Journal of Nutrition · doi:10.1007/s00394-019-02089-z · Cited by 35

Modified behavioural tests to detect white matter injury- induced motor deficits after intracerebral haemorrhage in mice

Chen, W., Xia, M., Guo, C., Jia, Z., Wang, J., Li, C., Li, M., Tang, X., Hu, R., Chen, Y., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-53263-6 · Cited by 34

The NADase enzyme CD38: an emerging pharmacological target for systemic sclerosis, systemic lupus erythematosus and rheumatoid arthritis

Peclat, T., Shi, B., Varga, J., & Chini, E. N. (2020) · Current Opinion in Rheumatology · doi:10.1097/bor.0000000000000737 · Cited by 35

A Bifunctional NAD+ for Profiling Poly-ADP-Ribosylation-Dependent Interacting Proteins

Lam, A. T., Zhang, X., Courouble, V. V., Strutzenberg, T. S., Pei, H., Stiles, B. L., Louie, S. G., Griffin, P. R., & Zhang, Y. (2021) · ACS Chemical Biology · doi:10.1021/acschembio.0c00937 · Cited by 34

NAD+ Metabolism as an Emerging Therapeutic Target for Cardiovascular Diseases Associated With Sudden Cardiac Death

Xu, W., Li, L., & Zhang, L. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00901 · Cited by 35

Nicotinamide riboside induces a thermogenic response in lean mice

Crisol, B., Veiga, C. B., Lenhare, L., Braga, R. R., Silva, V. R. R., da Silva, A. S. R., Cintra, D. E., de Moura, L. P., Pauli, J. R., & Ropelle, E. R. (2018) · Life Sciences · doi:10.1016/j.lfs.2018.09.015 · Cited by 31

NAD + supplementation prevents STING‐induced senescence in CD8 + T cells by improving mitochondrial homeostasis

Ye, B., Pei, Y., Wang, L., Meng, D., Zhang, Y., Zou, S., Li, H., Liu, J., Xie, Z., Tian, C., et al. (2024) · Journal of Cellular Biochemistry · doi:10.1002/jcb.30522 · Cited by 33

Implications of NAD + boosters in translational medicine

Kang, B. E., Choi, J., Stein, S., & Ryu, D. (2020) · European Journal of Clinical Investigation · doi:10.1111/eci.13334 · Cited by 32

Muscle mitochondrial remodeling by intermittent glucocorticoid drugs requires an intact circadian clock and muscle PGC1α

Quattrocelli, M., Wintzinger, M., Miz, K., Levine, D. C., Peek, C. B., Bass, J. T., & McNally, E. M. (2022) · Science Advances · doi:10.1126/sciadv.abm1189 · Cited by 30

Discovery of an NAD + analogue with enhanced specificity for PARP1

Zhang, X., Lam, A. T., Cheng, Q., Courouble, V. V., Strutzenberg, T. S., Li, J., Wang, Y., Pei, H., Stiles, B. L., Louie, S. G., et al. (2022) · Chemical Science · doi:10.1039/d1sc06256e · Cited by 30

NAD+ Metabolism and Diseases with Motor Dysfunction

Lundt, S., & Ding, S. (2021) · Genes · doi:10.3390/genes12111776 · Cited by 27

Verbascoside Elicits Its Beneficial Effects by Enhancing Mitochondrial Spare Respiratory Capacity and the Nrf2/HO-1 Mediated Antioxidant System in a Murine Skeletal Muscle Cell Line

Sciandra, F., Bottoni, P., Leo, M. D., Braca, A., Brancaccio, A., & Bozzi, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242015276 · Cited by 27

Translational geroscience: From invertebrate models to companion animal and human interventions

Lee, M. B., & Kaeberlein, M. R. (2018) · Translational Medicine of Aging · doi:10.1016/j.tma.2018.08.002 · Cited by 28

Nicotinamide Riboside Enhances In Vitro Beta-adrenergic Brown Adipose Tissue Activity in Humans

Nascimento, E. B. M., Moonen, M. P. B., Remie, C. M. E., Gariani, K., Jörgensen, J. A., Schaart, G., Hoeks, J., Auwerx, J. H., Lichtenbelt, W. D. V. M., & Schrauwen, P. (2021) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaa960 · Cited by 29

NAD depletion in skeletal muscle does not compromise muscle function or accelerate aging

Chubanava, S., Karavaeva, I. E., Ehrlich, A. M., Justicia, R. M., Basse, A. L., Kulik, I., Dalbram, E., Ahwazi, D., Heaselgrave, S. R., Trôst, K., et al. (2025) · Cell Metabolism · doi:10.1016/j.cmet.2025.04.002 · Cited by 30

Skeletal Muscle Mitochondria Dysfunction in Genetic Neuromuscular Disorders with Cardiac Phenotype

Ignatieva, E. V., Smolina, N., Kostareva, A. A., & Dmitrieva, R. I. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22147349 · Cited by 25

Aged Nicotinamide Riboside Kinase 2 Deficient Mice Present an Altered Response to Endurance Exercise Training

Deloux, R., Tannous, C., Ferry, A., Li, Z., & Mericskay, M. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01290 · Cited by 25

Short-term nicotinamide riboside treatment improves muscle quality and function in mice and increases cellular energetics and differentiating capacity of myogenic progenitors

Seldeen, K. L., Shahini, A., Thiyagarajan, R., Redae, Y. Z., Leiker, M., Rajabian, N., Dynka, A., Andreadis, S. T., & Troen, B. R. (2021) · Nutrition · doi:10.1016/j.nut.2021.111189 · Cited by 26

Emerging Role of Nicotinamide Riboside in Health and Diseases

Sharma, C., Donu, D., & Cen, Y. (2022) · Nutrients · doi:10.3390/nu14193889 · Cited by 24

Mechanisms of the NAD+ salvage pathway in enhancing skeletal muscle function

Su, M., Qiu, F., Li, Y., Che, T., Li, N., & Zhang, S. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1464815 · Cited by 27

Utrophin influences mitochondrial pathology and oxidative stress in dystrophic muscle

Kennedy, T. L., Moir, L., Hemming, S., Edwards, B., Squire, S. E., Davies, K. E., & Guiraud, S. (2017) · Skeletal Muscle · doi:10.1186/s13395-017-0139-5 · Cited by 23

The effects of nicotinamide adenine dinucleotide in cardiovascular diseases: Molecular mechanisms, roles and therapeutic potential

Zhang, X., Zhang, Y., Sun, A., & Ge, J. (2021) · Genes & Diseases · doi:10.1016/j.gendis.2021.04.001 · Cited by 24

Nicotinamide riboside has minimal impact on energy metabolism in mouse models of mild obesity

Cartwright, D. M., Oakey, L. A., Fletcher, R. S., Doig, C. L., Heising, S., Larner, D. P., Nasteska, D., Berry, C. E., Heaselgrave, S. R., Ludwig, C., et al. (2021) · Journal of Endocrinology · doi:10.1530/joe-21-0123 · Cited by 22

New Insights into the Genetics and Epigenetics of Aging Plasticity

Zhang, J., Wang, S., & Liu, B. (2023) · Genes · doi:10.3390/genes14020329 · Cited by 25

Meat Intake and the Dose of Vitamin B 3 – Nicotinamide: Cause of the Causes of Disease Transitions, Health Divides, and Health Futures?

Hill, L. J., & Williams, A. C. (2017) · International Journal of Tryptophan Research · doi:10.1177/1178646917704662 · Cited by 23

Nicotinamide mononucleotide ameliorates senescence in alveolar epithelial cells

Fang, T., Yang, H. J., Liu, L., Xiao, H., & Wei, X. (2021) · MedComm · doi:10.1002/mco2.62 · Cited by 22

Meta-analysis of NAD(P)(H) quantification results exhibits variability across mammalian tissues

Azouaoui, D., Choinière, M. R., Khan, M., Sayfi, S., Jaffer, S., Yousef, S., Patten, D. A., Green, A. E., & Menzies, K. J. (2023) · Scientific Reports · doi:10.1038/s41598-023-29607-8 · Cited by 24

Rejuvenating Aged Hematopoietic Stem Cells Through Improvement of Mitochondrial Function

Moon, J., Kim, H. R., & Shin, M. (2018) · Annals of Laboratory Medicine · doi:10.3343/alm.2018.38.5.395 · Cited by 24

CD38‐NADase is a new major contributor to Duchenne muscular dystrophic phenotype

de Zélicourt, A., Fayssoil, A., Dakouane‐Giudicelli, M., de Jesus, I., Karoui, A., Zarrouki, F., Lefebvre, F., Mansart, A., Launay, J., Piquereau, J., et al. (2022) · EMBO Molecular Medicine · doi:10.15252/emmm.202012860 · Cited by 23

Naringenin improves muscle endurance via activation of the Sp1-ERRγ transcriptional axis

Lv, Z., Meng, J., Yao, S., Xiao, F., Li, S., Shi, H., Cui, C., Chen, K., Luo, X., Ye, Y., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.113288 · Cited by 21

Complementary NAD+ replacement strategies fail to functionally protect dystrophin-deficient muscle

Frederick, D. W., McDougal, A. V., Semenas, M., Vappiani, J., Nuzzo, A., Ulrich, J. C., Becherer, J. D., Preugschat, F., Stewart, E. L., Sévin, D. C., et al. (2020) · Skeletal Muscle · doi:10.1186/s13395-020-00249-y · Cited by 21

The one-step fabrication of porous hASC-laden GelMa constructs using a handheld printing system

Jo, S., Lee, J., Lee, H., Ryu, D., & Kim, G. (2023) · npj Regenerative Medicine · doi:10.1038/s41536-023-00307-1 · Cited by 20

NAD + repletion produces no therapeutic effect in mice with respiratory chain complex III deficiency and chronic energy deprivation

Purhonen, J., Rajendran, J., Tegelberg, S., Smolander, O., Pirinen, E., Kallijärvi, J., & Fellman, V. (2018) · The FASEB Journal · doi:10.1096/fj.201800090r · Cited by 22

The effect of NAMPT deletion in projection neurons on the function and structure of neuromuscular junction (NMJ) in mice

Lundt, S., Zhang, N., Wang, X., Polo‐Parada, L., & Ding, S. (2020) · Scientific Reports · doi:10.1038/s41598-019-57085-4 · Cited by 21

NAD+: An old but promising therapeutic agent for skeletal muscle ageing

Xu, Y., & Xiao, W. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.102106 · Cited by 20

Fabrication of fully aligned self-assembled cell-laden collagen filaments for tissue engineering via a hybrid bioprinting process

Kim, J., Lee, H., Lee, G., Ryu, D., & Kim, G. (2024) · Bioactive Materials · doi:10.1016/j.bioactmat.2024.02.020 · Cited by 20

Physical exercise elicits UPRmt in the skeletal muscle: The role of c-Jun N-terminal kinase

Gaspar, R. S., Katashima, C. K., Crisol, B., Carneiro, F. S., Sampaio, I. H., Silveira, L. R., da Silva, A. S. R., Cintra, D. E., Pauli, J. R., & Ropelle, E. R. (2023) · Molecular Metabolism · doi:10.1016/j.molmet.2023.101816 · Cited by 20

Sulfur amino acid supplementation displays therapeutic potential in a C. elegans model of Duchenne muscular dystrophy

Ellwood, R. A., Slade, L., Lewis, J., Torregrossa, R., Sudevan, S., Piasecki, M., Whiteman, M., Etheridge, T., & Szewczyk, N. J. (2022) · Communications Biology · doi:10.1038/s42003-022-04212-z · Cited by 18

SIRT1-dependent restoration of NAD+ homeostasis after increased extracellular NAD+ exposure

Buonvicino, D., Ranieri, G., Pittelli, M. G., Lapucci, A., Bragliola, S., & Chiarugi, A. (2021) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2021.100855 · Cited by 17

Drosophila exercise, an emerging model bridging the fields of exercise and aging in human

Ding, M., Li, H., & Zheng, L. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.966531 · Cited by 19

Nicotinamide riboside supplementation confers marginal metabolic benefits in obese mice without remodeling the muscle acetyl-proteome

Williams, A. S., Koves, T. R., Pettway, Y. D., Draper, J. A., Slentz, D. H., Grimsrud, P. A., Ilkayeva, O., & Muoio, D. M. (2021) · iScience · doi:10.1016/j.isci.2021.103635 · Cited by 17

Metabolic regulation in adult and aging skeletal muscle stem cellsPreprint

Sartorelli, V., & Ciuffoli, V. (2024) · Genes & Development · doi:10.1101/gad.352277.124 · Cited by 19

Nicotinamide Riboside Supplementation to Suckling Male Mice Improves Lipid and Energy Metabolism in Skeletal Muscle and Liver in Adulthood

Serrano, A., Palou, A., Bonet, M. L., & Ribot, J. (2022) · Nutrients · doi:10.3390/nu14112259 · Cited by 16

NAD+ enhances ribitol and ribose rescue of α-dystroglycan functional glycosylation in human FKRP-mutant myotubes

Ortiz‐Cordero, C., Magli, A., Dhoke, N. R., Kuebler, T. S., Selvaraj, S., Oliveira, N. A. D. J., Zhou, H., Sham, Y. Y., Bang, A. G., & Perlingeiro, R. C. R. (2021) · eLife · doi:10.7554/elife.65443 · Cited by 16

Improvement of tissue‐specific distribution and biotransformation potential of nicotinamide mononucleotide in combination with ginsenosides or resveratrol

Bai, L., Yau, L., Tong, T., Chan, W.-H., Zhang, W., & Jiang, Z. (2022) · Pharmacology Research & Perspectives · doi:10.1002/prp2.986 · Cited by 14

Synthesis of β‐Nicotinamide Riboside Using an Efficient Two‐Step Methodology

Zhang, N., & Sauve, A. A. (2017) · Current Protocols in Nucleic Acid Chemistry · doi:10.1002/cpnc.43 · Cited by 16

NAD+ Therapeutics and Skeletal Muscle Adaptation to Exercise in Humans

Campelj, D. G., & Philp, A. (2022) · Sports Medicine · doi:10.1007/s40279-022-01772-2 · Cited by 20

Nicotinamide riboside kinases regulate skeletal muscle fiber-type specification and are rate-limiting for metabolic adaptations during regeneration

Sonntag, T., Ancel, S., Karaz, S., Cichosz, P., Jacot, G. E., Giner, M. P., Sanchez-Garcia, J. L., Pannérec, A., Moco, S., Sorrentino, V., et al. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.1049653 · Cited by 16

Transcriptome changes during the initiation and progression of Duchenne muscular dystrophy in Caenorhabditis elegans

Hrach, H., O’Brien, S., Steber, H. S., Newbern, J. M., Rawls, A., & Mangone, M. (2020) · Human Molecular Genetics · doi:10.1093/hmg/ddaa055 · Cited by 15

Chemo-enzymatic synthesis of isotopically labeled nicotinamide riboside

Tran, A., Yokose, R., & Cen, Y. (2018) · Organic & Biomolecular Chemistry · doi:10.1039/c8ob00552d · Cited by 14

IL36G-producing neutrophil-like monocytes promote cachexia in cancer

Hayashi, Y., Kamimura-Aoyagi, Y., Nishikawa, S., Noka, R., Iwata, R., Iwabuchi, A., Watanabe, Y., Matsunuma, N., Yuki, K., Kobayashi, H., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-51873-x · Cited by 15

Nicotinamide improves NAD + levels to protect against acetaminophen-induced acute liver injury in mice

Xu, J., Zhang, L., Jiang, R., Hu, K., Hu, D., Liao, C., Jiang, S., Yang, Y., Huang, J., Tang, L. P., et al. (2021) · Human & Experimental Toxicology · doi:10.1177/09603271211014573 · Cited by 13

Reduced Levels of NAD in Skeletal Muscle and Increased Physiologic Frailty Are Associated With Viral Coinfection in Asymptomatic Middle-Aged Adults

Tran, T., Pencina, K. M., Schultz, M. B., Li, Z., Ghattas, C., Lau, J., Sinclair, D. A., & Montano, M. A. (2022) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000002852 · Cited by 13

Nicotinamide N-methyltransferase protects against deoxynivalenol-induced growth inhibition by suppressing pro-inflammatory cytokine expression

Liu, A., Guo, M., He, L., Martínez, M., Martínez, M., López-Torres, B., Martínez‐Larrañaga, M., Wang, X., Anadón, A., & Arés, I. (2022) · Food and Chemical Toxicology · doi:10.1016/j.fct.2022.112969 · Cited by 13

The SIRT1 activator SRT2104 exerts exercise mimetic effects and promotes Duchenne muscular dystrophy recovery

Giovarelli, M., Zecchini, S., Casati, S. R., Lociuro, L., Gjana, O., Mollica, L., Pisanu, E., Mbissam, H. D., Cappellari, O., De Santis, C., et al. (2025) · Cell Death & Disease · doi:10.1038/s41419-025-07595-z · Cited by 12

Silencing of Poly(ADP-Ribose) Polymerase-2 Induces Mitochondrial Reactive Species Production and Mitochondrial Fragmentation

Jankó, L., Kovàcs, T., Laczik, M., Sári, Z., Ujlaki, G., Kis, G. N., Horváth, I., Antal, M., Vı́gh, L., Bálint, B. L., et al. (2021) · Cells · doi:10.3390/cells10061387 · Cited by 12

NAD + depletion is central to placental dysfunction in an inflammatory subclass of preeclampsia

Jahan, F., Vasam, G., Cariaco, Y., Nik-Akhtar, A., Green, A. E., Menzies, K. J., & Bainbridge, S. A. (2024) · Life Science Alliance · doi:10.26508/lsa.202302505 · Cited by 12

Nutrient Metabolites Associated With Low D3Cr Muscle Mass, Strength, and Physical Performance in Older Men

Hetherington‐Rauth, M., Johnson, E. M., Migliavacca, E., Parimi, N., Langsetmo, L., Hepple, R. T., Grzywinski, Y., Corthésy, J., RYAN, T. E., Ferrucci, L., et al. (2023) · The Journals of Gerontology Series A · doi:10.1093/gerona/glad217 · Cited by 12

Nutraceutical and pharmaceutical cocktails did not improve muscle function or reduce histological damage in D2-mdx mice

Spaulding, H. R., Quindry, T. S., Hammer, K., Quindry, J. C., & Selsby, J. T. (2019) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00162.2019 · Cited by 12

NAD+ metabolism and retinal degeneration (Review)

Pîrvu, A. S., Andrei, A. M., Stănciulescu, E. C., Baniţă, I. M., Pisoschi, C. G., Jurja, S., & Ciuluvica, R. C. (2021) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2021.10102 · Cited by 12

Rewinding the Clock: Emerging Pharmacological Strategies for Human Anti-Aging Therapy

Delrue, C., Speeckaert, R., & Speeckaert, M. M. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26199372 · Cited by 12

Caenorhabditis elegans as a Model System for Duchenne Muscular Dystrophy

Ellwood, R. A., Piasecki, M., & Szewczyk, N. J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22094891 · Cited by 11

Nutraceutical and pharmaceutical cocktails did not preserve diaphragm muscle function or reduce muscle damage in D2‐mdx mice

Spaulding, H. R., Quindry, T. S., Quindry, J. C., & Selsby, J. T. (2020) · Experimental Physiology · doi:10.1113/ep087887 · Cited by 11

A macrodomain-linked immunosorbent assay (MLISA) for mono-ADP-ribosyltransferases

Chen, J., Lam, A. T., & Zhang, Y. (2017) · Analytical Biochemistry · doi:10.1016/j.ab.2017.12.019 · Cited by 11

Excessive exercise elicits poly (ADP-ribose) Polymerase-1 activation and global protein PARylation driving muscle dysfunction and performance impairment

Crisol, B., Rocha, M. B., Franco, B., Morelli, A. P., Katashima, C. K., Scylas, J. A., Carneiro, F. S., Braga, R. R., Brícola, R. S., de Azambuja, G., et al. (2025) · Molecular Metabolism · doi:10.1016/j.molmet.2025.102135 · Cited by 9

Potential Therapeutic Interventions Targeting NAD+ Metabolism for ALS

Lundt, S., & Ding, S. (2024) · Cells · doi:10.3390/cells13171509 · Cited by 12

Nicotinamide-riboside shifts the differentiation of human primary white adipocytes to beige adipocytes impacting substrate preference and uncoupling respiration through SIRT1 activation and mitochondria-derived reactive species production

Nagy, L., Rauch, B., Szerafin, T., Uray, K., Tóth, A., & Bai, P. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.979330 · Cited by 8

Dietary NMN supplementation enhances motor and NMJ function in ALS

Lundt, S., Zhang, N., Polo‐Parada, L., Wang, X., & Ding, S. (2024) · Experimental Neurology · doi:10.1016/j.expneurol.2024.114698 · Cited by 9

Development of Second Generation Activity-Based Chemical Probes for Sirtuins

Curry, A. M., Barton, E. E., Kang, W., Mongeluzi, D. V., & Cen, Y. (2020) · Molecules · doi:10.3390/molecules26010011 · Cited by 8

Transplantation of Muscle Stem Cell Mitochondria Rejuvenates the Bioenergetic Function of Dystrophic MusclePreprint

Mohiuddin, M., Choi, J. J., Lee, N. H., Jeong, H., Anderson, S. E., Han, W. M., Aliya, B., Peykova, T. Z., Verma, S., Garcı́a, A. J., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.04.17.017822 · Cited by 8

Tankyrase-1 regulates RBP-mediated mRNA turnover to promote muscle fiber formation

Mubaid, S., Sánchez, B. J., Algehani, R., Skopenkova, V. V., Adjibade, P., Hall, D. T., Busque, S., Lian, X. J., Ashour, K., Tremblay, A. K., et al. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae059 · Cited by 8

Differences in Extracellular NAD+ and NMN Metabolism on the Surface of Vascular Endothelial Cells

Jabłońska, P., Mierzejewska, P., Tomczyk, M., Koszałka, P., Frańczak, M., Kawecka, A., Kutryb-Zając, B. A., Braczko, A., Smolenski, R. T., & Slominska, E. M. (2022) · Biology · doi:10.3390/biology11050675 · Cited by 7

Age-related schwannomatosis with potential exosome-mediated contribution to prostate hyperplasia: a case report and mini-review

Chignon‐Sicard, B., Hofman, V., Chevallier, D., Cucchi, J. M., Ilié, M., Dadone‐Montaudié, B., Paul, F., Carpentier, X., Quintens, H., Bence-Gauchiez, C., et al. (2019) · Therapeutic Advances in Urology · doi:10.1177/1756287219875578 · Cited by 6

Replenishing NAD+ content reduces aspects of striated muscle disease in a dog model of Duchenne muscular dystrophy

Cardoso, D., Barthélémy, I., Blot, S., & Muchir, A. (2023) · Skeletal Muscle · doi:10.1186/s13395-023-00328-w · Cited by 6

Differentially disrupted spinal cord and muscle energy metabolism in spinal and bulbar muscular atrophy

DeBartolo, D., Arnold, F. J., Liu, Y., Molotsky, E., Tang, H., & Merry, D. E. (2024) · JCI Insight · doi:10.1172/jci.insight.178048 · Cited by 7

Nicotinamide riboside alleviates cisplatin-induced peripheral neuropathy via SIRT2 activation

Acklin, S., Sadhukhan, R., Du, W., Patra, M., Cholia, R. P., & Xia, F. (2022) · Neuro-Oncology Advances · doi:10.1093/noajnl/vdac101 · Cited by 6

Dietary supplementation with nicotinamide riboside improves fetal growth under hypoglycemia

Lee, S. R., Jeong, S. H., Mukae, M., Kim, S.-Y., Ko, J., Kwun, H., & Hong, E. (2023) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2023.109310 · Cited by 5

Nicotinamide Riboside, an NAD + Precursor, Protects Against Cardiac Mitochondrial Dysfunction in Fetal Guinea Pigs Exposed to Gestational Hypoxia

Thompson, L. P., Song, H., & Hartnett, J. (2023) · Reproductive Sciences · doi:10.1007/s43032-023-01387-6 · Cited by 5

Remission of social behavior impairment by oral administration of a precursor of NAD in CD157, but not in CD38, knockout mice

Gerasimenko, M., & Higashida, H. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1166609 · Cited by 5

Small Molecule Regulators Targeting NAD+ Biosynthetic Enzymes

Cen, Y., Curry, A. M., & White, D. S. (2021) · Current Medicinal Chemistry · doi:10.2174/0929867328666210531144629 · Cited by 6

Enhancing NAD+ Metabolome in Cardiovascular Diseases: Promises and Considerations

Jahan, F., & Bagchi, R. A. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.716989 · Cited by 5

The Potential of Targeting APE1/Ref-1 as a Therapeutic Intervention for Duchenne Muscular Dystrophy

Lalunio, H., Stupka, N., Goodman, C. A., & Hayes, A. (2024) · Antioxidants and Redox Signaling · doi:10.1089/ars.2024.0620 · Cited by 4

Mitochondrial Activation and Therapeutics: Innovations in Cell- and Organelle-Specific Medicine

Sato, I., Shiraishi, M., Norota, K., Shiraki, K., & Yamada, Y. (2025) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b25-00218 · Cited by 5

Need for NAD+: Focus on Striated Muscle Laminopathies

Cardoso, D., & Muchir, A. (2020) · Cells · doi:10.3390/cells9102248 · Cited by 5

Effects of muscle damage on 31phosphorus magnetic resonance spectroscopy indices of energetic status and sarcolemma integrity in young mdx mice

Lopez, C., Batra, A., Moslemi, Z., Rennick, A., Guice, K., Zeng, H., Walter, G. A., & Forbes, S. C. (2021) · NMR in Biomedicine · doi:10.1002/nbm.4659 · Cited by 4

Increased SIRT3 combined with PARP inhibition rescues motor function of SBMA mice

Castro, D. R. G., Mazuk, J. R., Heine, E. M., Simpson, D., Pinches, R. S., Lozzi, C., Hoffman, K. L., Morrin, P., Mathis, D., Lebedev, M. V., et al. (2023) · iScience · doi:10.1016/j.isci.2023.107375 · Cited by 4

Replenishing NAD+ content reduces aspects of striated muscle disease in a dog model of Duchenne muscular dystrophy

Cardoso, D., Barthélémy, I., Blot, S., & Muchir, A. (2023) · Skeletal Muscle · doi:10.1186/s13395-023-00328-w · Cited by 6

Restoration of NAD + homeostasis protects C2C12 myoblasts and mouse levator ani muscle from mechanical stress-induced damage

Huang, G., He, Y., Li, H., Zhou, M., Zuo, X., & Zhao, Z. (2022) · Animal Cells and Systems · doi:10.1080/19768354.2022.2106303 · Cited by 7

Study of muscle regeneration in muscular dystrophies

Mechler, F., & Molnar, J. M. (1997) · Neuromuscular Disorders · doi:10.1016/s0960-8966(97)87352-x

277P Single-nuclei RNAseq in myotonic dystrophy type I: DMPK accumulation and myofiber repair

Todorow, V., Hayashi, S., Meinke, P., Schoser, B. G. H., & Nishino, I. (2024) · Neuromuscular Disorders · doi:10.1016/j.nmd.2024.07.095

RNA therapies are delivering as therapies for neuromuscular dystrophy patients: Editorial for the special issue on RNA therapies in Journal of Neuromuscular Diseases

Aartsma-Rus, A. M., & Takeda, S. (2025) · Journal of Neuromuscular Diseases · doi:10.1177/22143602251403854