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FOS licenses early events in stem cell activation driving skeletal muscle regeneration

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Antioxidant Alternatives in the Treatment of Amyotrophic Lateral Sclerosis: A Comprehensive Review

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Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease

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Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1G93A Mice

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Nicotinamide riboside, an NAD+ precursor, attenuates the development of liver fibrosis in a diet-induced mouse model of liver fibrosis

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Targeting CD38-dependent NAD+ metabolism to mitigate multiple organ fibrosis

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Nicotinamide adenine dinucleotide metabolism in the immune response, autoimmunity and inflammageing

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NAD+ repletion with niacin counteracts cancer cachexia

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Nicotinamide Pathway-Dependent Sirt1 Activation Restores Calcium Homeostasis to Achieve Neuroprotection in Spinocerebellar Ataxia Type 7

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Poly (ADP-Ribose) polymerase 1 and parthanatos in neurological diseases: From pathogenesis to therapeutic opportunities

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Mitochondria: An Integrative Hub Coordinating Circadian Rhythms, Metabolism, the Microbiome, and Immunity

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Dietary strategies with anti-aging potential: Dietary patterns and supplements

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Identification of evolutionary and kinetic drivers of NAD-dependent signaling

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The role of FXR and TGR5 in reversing and preventing progression of Western diet–induced hepatic steatosis, inflammation, and fibrosis in mice

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Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity

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Rescue of biosynthesis of nicotinamide adenine dinucleotide protects the heart in cardiomyopathy caused by lamin A/C gene mutation

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NAD+ and NAFLD – caution, causality and careful optimism

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Biomimetic Conductive Hydrogel Scaffolds with Anisotropy and Electrical Stimulation for In Vivo Skeletal Muscle Reconstruction

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Ergothioneine improves healthspan of aged animals by enhancing cGPDH activity through CSE-dependent persulfidation

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NAD+ metabolism-based immunoregulation and therapeutic potential

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NAD+: A key metabolic regulator with great therapeutic potential

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NAD+ Deficits in Age-Related Diseases and Cancer

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A Microfluidic Device to Fabricate One‐Step Cell Bead‐Laden Hydrogel Struts for Tissue Engineering

Kim, J., Lee, H., Jin, E., Jo, Y., Kang, B. E., Ryu, D., & Kim, G. (2021) · Small · doi:10.1002/smll.202106487 · Cited by 51

Nicotinamide riboside promotes autolysosome clearance in preventing doxorubicin-induced cardiotoxicity

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Emerging strategies, applications and challenges of targeting NAD+ in the clinic

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The Interplay of Mitophagy and Inflammation in Duchenne Muscular Dystrophy

Reid, A. L., & Alexander, M. S. (2021) · Life · doi:10.3390/life11070648 · Cited by 51

Roles of NAD + in Health and AgingPreprint

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α-Amino-β-carboxymuconate-ε-semialdehyde Decarboxylase (ACMSD) Inhibitors as Novel Modulators of De Novo Nicotinamide Adenine Dinucleotide (NAD+) Biosynthesis

Pellicciari, R., Liscio, P., Giacchè, N., Franco, F., Carotti, A., Robertson, J., Cialabrini, L., Katsyuba, E., Raffaelli, N., & Auwerx, J. H. (2018) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.7b01254 · Cited by 48

NAD+ and cardiovascular diseases

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Muscle aging and sarcopenia: The pathology, etiology, and most promising therapeutic targets

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Nicotinamide Riboside and Pterostilbene Cooperatively Delay Motor Neuron Failure in ALS SOD1G93A Mice

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Mitochondrial hydrogen sulfide supplementation improves health in the C. elegans Duchenne muscular dystrophy model

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NAD+ Metabolism and Immune Regulation: New Approaches to Inflammatory Bowel Disease Therapies

Chen, C., Yan, W., Tao, M., & Fu, Y. (2023) · Antioxidants · doi:10.3390/antiox12061230 · Cited by 44

Nicotinamide Adenine Dinucleotide in Aging Biology: Potential Applications and Many Unknowns

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Regulatory Effects of NAD + Metabolic Pathways on Sirtuin Activity

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Pulsed glucocorticoids enhance dystrophic muscle performance through epigenetic-metabolic reprogramming

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Nicotinamide riboside supplementation does not alter whole‐body or skeletal muscle metabolic responses to a single bout of endurance exercise

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A ribose-functionalized NAD+ with unexpected high activity and selectivity for protein poly-ADP-ribosylation

Zhang, X., Cheng, Q., Chen, J., Lam, A. T., Lu, Y., Dai, Z., Pei, H., Evdokimov, N. M., Louie, S. G., & Zhang, Y. (2019) · Nature Communications · doi:10.1038/s41467-019-12215-4 · Cited by 42

Host–microbiome interactions in nicotinamide mononucleotide (NMN) deamidation

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NAD+ Metabolism, Metabolic Stress, and Infection

Groth, B., Venkatakrishnan, P., & Lin, S.-J. (2021) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2021.686412 · Cited by 42

A systems-approach to NAD+ restoration

Conlon, N. J., & Ford, D. (2022) · Biochemical Pharmacology · doi:10.1016/j.bcp.2022.114946 · Cited by 41

Replenishing NAD+ content reduces aspects of striated muscle disease in a dog model of Duchenne muscular dystrophy

Cardoso, D., Barthélémy, I., Blot, S., & Muchir, A. (2023) · Skeletal Muscle · doi:10.1186/s13395-023-00328-w · Cited by 6

Restoration of NAD + homeostasis protects C2C12 myoblasts and mouse levator ani muscle from mechanical stress-induced damage

Huang, G., He, Y., Li, H., Zhou, M., Zuo, X., & Zhao, Z. (2022) · Animal Cells and Systems · doi:10.1080/19768354.2022.2106303 · Cited by 7

Study of muscle regeneration in muscular dystrophies

Mechler, F., & Molnar, J. M. (1997) · Neuromuscular Disorders · doi:10.1016/s0960-8966(97)87352-x

277P Single-nuclei RNAseq in myotonic dystrophy type I: DMPK accumulation and myofiber repair

Todorow, V., Hayashi, S., Meinke, P., Schoser, B. G. H., & Nishino, I. (2024) · Neuromuscular Disorders · doi:10.1016/j.nmd.2024.07.095

RNA therapies are delivering as therapies for neuromuscular dystrophy patients: Editorial for the special issue on RNA therapies in Journal of Neuromuscular Diseases

Aartsma-Rus, A. M., & Takeda, S. (2025) · Journal of Neuromuscular Diseases · doi:10.1177/22143602251403854