NAD + repletion improves muscle function in muscular dystrophy and counters global PARylation

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Subramanian, A., Tamayo, P., Mootha, V. K., Mukherjee, S., Ebert, B. L., Gillette, M. A., Paulovich, A., Pomeroy, S. L., Golub, T. R., Lander, E. S., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506580102 · Cited by 53,625

Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α

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Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy · doi:10.4161/auto.19496 · Cited by 3,996

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

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Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase

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Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis

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NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

Cantó, C., Menzies, K. J., & Auwerx, J. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.05.023 · Cited by 1,648

Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging

Gomes, A. P., Price, N. L., Ling, A. J. Y., Moslehi, J. J., Montgomery, M. K., Rajman, L., White, J. P., Teodoro, J. S., Wrann, C. D., Hubbard, B. P., et al. (2013) · Cell · doi:10.1016/j.cell.2013.11.037 · Cited by 1,482

Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice

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Cellular and molecular mechanisms of muscle atrophy

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Macroscale pseudo-spheroids fabricated using methacrylated collagen-coated cells

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The inhibition of the mitochondrial F 1 F O -ATPase activity when activated by Ca 2+ opens new regulatory roles for NAD +

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Deletion of Nmnat1 in Skeletal Muscle Leads to the Reduction of NAD+ Levels but Has No Impact on Skeletal Muscle Morphology and Fiber Types

Karim, M., Iqbal, T., Nawaz, A., Yaku, K., & Nakagawa, T. (2023) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.69.184 · Cited by 4

Muscle Stem Cell Immunostaining

Wang, S., Zhang, B., Addicks, G. C., Zhang, H., Menzies, K. J., & Zhang, H. (2018) · Current Protocols in Mouse Biology · doi:10.1002/cpmo.47 · Cited by 4

Protein Acetylation and NAD+ Homeostasis in Aging Muscle

Ji, L. L. (2025) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-88361-3_17 · Cited by 3

Retention of stress susceptibility in the mdx mouse model of Duchenne muscular dystrophy after PGC-1α overexpression or ablation of IDO1 or CD38

Johnson, E. E., Southern, W. M., Doud, B., Steiger, B., Razzoli, M., Bartolomucci, A., & Ervasti, J. M. (2024) · Human Molecular Genetics · doi:10.1093/hmg/ddad206 · Cited by 3

Chemoenzymatic Preparation of 4′‐Thioribose NAD+

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Oral administration of ginseng berry concentrate improves lactate metabolism and increases endurance performance in mice

Jin, E., Wei, S., Jo, Y., Nguyen, T. T., Ji, M., Paik, M., Jeong, J., Im, S. J., & Ryu, D. (2023) · BMB Reports · doi:10.5483/bmbrep.2023-0040 · Cited by 3

NAD+ dyshomeostasis in RYR1-related myopathies

Lawal, T. A., Riekhof, W., Groom, L. A., Varma, P., Chrismer, I. C., Kokkinis, A. D., Grunseich, C., Witherspoon, J. W., Razaqyar, M. S., Sinaii, N., et al. (2025) · Skeletal Muscle · doi:10.1186/s13395-025-00390-6 · Cited by 3

β-Hydroxy-β-methylbutyrate enhances fast-twitch muscle and mitochondrial function, histopathology and mTORC1 signalling in the mdx dystrophic mouse

Giourmas, N., Lalunio, H., Wu, C., Bagaric, R. M., Calzoni, M., Goodman, C. A., & Hayes, A. W. (2025) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00722.2025 · Cited by 2

β-Nicotinamide mononucleotide prevents senescence and lipid accumulation in hepatic stellate cells by restoring SIRT1 function

Saka, T., Hayashi, R., Yoshino, Y., Mitsui, T., Maruyama, H., Kono, H., Kawaguchi, M., Nakagawa, H., Ikari, A., & Endo, S. (2026) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2026.112012 · Cited by 2

Antibodies against SARS-CoV-2 non-structural protein 3 cross-react with human muscle cells and neuroglial cells

Yang, X., Liu, T., Jiang, S., Zhang, Z., Fu, Y., Li, Z.-L., Hu, J., & Yuan, S. (2024) · Vaccine · doi:10.1016/j.vaccine.2024.01.074 · Cited by 2

Nicotinamide Phosphoribosyltransferase Acetylation Mediating Muscle Dysfunction Contributes to Sleep Apnoea in Obesity

Zhang, L., Yan, Y. R., Li, S. Q., Lin, Y. N., Wang, Y., Wang, Y. Q., Li, N., Lu, F., Sun, X. W., Zhang, L. Y., et al. (2025) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.13693 · Cited by 3

Poverty and Pellagra’s Penumbras

Williams, A. C., & Hill, L. J. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.100001 · Cited by 3

Accounting for NAD Concentrations in Genome-Scale Metabolic Models Captures Important Metabolic Alterations in NAD-Depleted Systems

Sauter, R., Sharma, S. A., & Heiland, I. (2024) · Biomolecules · doi:10.3390/biom14050602 · Cited by 2

Pharmacological Approaches for Modulating Sirtuins

Kane, A. E., & Sinclair, D. A. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813499-3.00006-x · Cited by 2

Molecular physiological studies on health effects of dietary nicotinamide riboside, a vitamin B3

Shi, W. (2019) · doi:10.18174/471911 · Cited by 2

NAD+ Metabolism in Aging

Palikhe, S., & Nakagawa, T. (2022) · Springer eBooks · doi:10.1007/978-981-16-7977-3_8 · Cited by 1

Computer assisted discovery of novel nicotinamide phosphoribosyltransferase agonists to combat muscle atrophy

Li, L., Wang, R., Zhu, J., Cao, F., Min, J., Ouyang, D., & Lin, L. (2025) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2025.109296 · Cited by 1

Non-cell autonomous effect of neuronal nicotinamide phosphoribosyl transferase on the function of neuromuscular junctions

Lundt, S., & Ding, S. (2020) · Neural Regeneration Research · doi:10.4103/1673-5374.290893 · Cited by 1

Transcriptome profiling of skeletal muscles from Korean patients with Bethlem myopathy

Lee, S., Hong, J., Lee, J. H., Choi, Y., & Park, H. J. (2023) · Medicine · doi:10.1097/md.0000000000033122 · Cited by 1

Skeletal muscle vulnerability in a child with Pitt-Hopkins syndrome

Chiu, C., Küchler, A., Depienne, C., Preuße, C., Marina, A. D., Reis, A., Kaiser, F. J., Nolte, K. W., Hentschel, A., Schara, U., et al. (2024) · Skeletal Muscle · doi:10.1186/s13395-024-00348-0 · Cited by 1

Critical Assessment of the mdx Mouse with Ex Vivo Eccentric Contraction of the Diaphragm Muscle

Addicks, G. C., Marshall, P., Jasmin, B. J., Renaud, J., Zhang, H., & Menzies, K. J. (2018) · Current Protocols in Mouse Biology · doi:10.1002/cpmo.49 · Cited by 1

The effects of acute nicotinamide riboside supplementation on substrate utilisation and 5km time-trial performance

Gray, E. L. (2019) · University of Birmingham Institutional Research Archive (University of Birmingham) · Cited by 1

The TAS1R2 sweet taste receptor regulates skeletal muscle mass and fitnessPreprint

Kyriazis, G. A., Serrano, J., Boyd, J., Mason, C., Smith, K., Károlyi, K., Kondo, S., Brown, I., Maurya, S. K., Meshram, N. N., et al. (2023) · Research Square · doi:10.21203/rs.3.rs-2475555/v1 · Cited by 1

Vitamin B3 salvage and NAD\(^+\) metabolism in skeletal muscle

Fletcher, R. S. (2017) · University of Birmingham Institutional Research Archive (University of Birmingham)

NAD + Modulation

Katsyuba, E., & Auwerx, J. H. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813499-3.00003-4

Consecutive signaling pathways are activated in progression of Duchenne muscular dystrophy in C. elegansPreprint

Hrach, H., Steber, H. S., Newbern, J. M., Rawls, A., & Mangone, M. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/532465

Induction of the nicotinamide riboside kinase NAD + salvage pathway in skeletal myopathy of H6PDH KO micePreprint

Doig, C. L., Zielinska, A. E., Fletcher, R. S., Oakey, L. A., Elhassan, Y., Garten, A., Cartwright, D., Heising, S., Alsheri, A., Watson, D. G., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/567297

Mitochondria as a Key Player in Aging

Banerjee, R., & Rath, P. C. (2020) · Springer eBooks · doi:10.1007/978-981-32-9005-1_10

Tissue repair and stress responses of aged skin epidermis

Wong, W. (2020) · Digital Repository Service (Northeastern University) · doi:10.17760/d20383670

Scope to develop sirtuins modulators as a therapy to attenuate cardiac complications

Bugga, P., & Banerjee, S. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-814118-2.00018-5

Transcriptome and whole genome sequencing profiles in Leber’s Hereditary Optic Neuropathy 14484T>C mutation carrying monozygotic twins reveal that prostanoid receptor is a possible modifier for LHON manifestationPreprint

Tun, K. K. Z., Toosaranont, J., Kaewsutthi, S., Grove, H., Ruchadaariyachat, S., Suthammarak, W., Chuenkongkaew, W. L., Lertrit, P., Suktitipat, B., & Mitrpant, C. (2021) · Research Square · doi:10.21203/rs.3.rs-604500/v1

子宮内膜癌細胞株における抗癌剤感受性の検討(子宮体部悪性腫瘍VI, 第57回日本産科婦人科学会学術講演会)

茂木, 真., 新美, 茂., 高倉, 聡., 柳田, 聡., 岡本, 愛., 落合, 和., & 田中, 忠. (2005) · 日本産科婦人科學會雜誌

Nutraceuticals for targeting NAD+ to restore mitochondrial function

Garten, A., & Lavery, G. G. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-90256-4.00019-9

The vitamin B 3 analogue nicotinamide riboside has only very minor effects on reducing muscle damage in mdx micePreprint

Stan, T. L., Vijver, D. V. D., Verhaart, I. E. C., & Aartsma-Rus, A. M. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.02.02.526793

Nicotinamide Mononucleotide (NMN) as a Solution of Decrease Nicotinamide Adenine Dinucleotide (NAD+) in Aging

Permatasari, N. K. M., Putra, I. G. N. A. K. W. B., & Purnamasidhi, ‪. A. W. (2023) · International Journal of Research and Review · doi:10.52403/ijrr.20230871

NAD + depletion and altered mitochondrial function are key to the establishment of placental dysfunction in an inflammatory-driven subclass of preeclampsiaPreprint

Jahan, F., Vasam, G., Cariaco, Y., Nik-Akhtar, A., Green, A., Menzies, K. J., & Bainbridge, S. A. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.09.09.556974

Impact of the NAD+ salvage pathway on the motor system and bioenergetics

Lundt, S. (2023) · MOspace Institutional Repository (University of Missouri) · doi:10.32469/10355/96990

O papel do exercício físico no desequilíbrio mitonuclear e UPRmt na musculatura esquelética de camundongos idosos

Cordeiro, A. V. (2019) · doi:10.47749/t/unicamp.2019.1157580

Effects of nicotinamide riboside on stressed/fatigued barrow carcass characteristics and loin chop color stability

Gravely, M. E., Hennesy, H. M., Alambarrio, D. A., Ellis, O. G., Xu, X., Stelzleni, A. M., & Gonzalez, J. M. (2025) · Meat Science · doi:10.1016/j.meatsci.2025.109772

Coenzyme I and Skeletal Muscle Disorders

Jiang, Z., Luo, L., Qin, Y., Zhou, Y., & Zhao, F. (2025) · Springer eBooks · doi:10.1007/978-981-97-9877-3_30

Identification and functional analysis of nucleoside hydrolases involved in the degradation of nicotinamide ribose to nicotinamide in kale (Brassica oleracea L. var. acephala DC.)

Hao, T., Liu, R., Tang, Z., Li, Y., Qu, W., Luo, W., Gui, L., Zhu, P., & Zhang, B. (2025) · Industrial Crops and Products · doi:10.1016/j.indcrop.2025.122186

Additional file 1 of Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study

Liao, B., Zhao, Y., Wang, D., Zhang, X., Hao, X., & Hu, M. (2021) · Figshare · doi:10.6084/m9.figshare.14936274

Additional file 1 of Skeletal muscle vulnerability in a child with Pitt-Hopkins syndrome

Chiu, C., Küchler, A., Depienne, C., Preuße, C., Marina, A. D., Reis, A., Kaiser, F. J., Nolte, K. W., Hentschel, A., Schara, U., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26333303

Effets de l’exercice et d’une modulation du métabolisme du NAD sur la fonction cardiaque et musculaire dans la cardiomyopathie dilatée

Deloux, R. (2018) · theses.fr (ABES) · doi:10.70675/187a7874z7c88z4ab7z9392zc08078be5b17

Rôle de la PARylation sur l’apparition des troubles cardiovasculaires dans la progéria de Hutchinson-Gilford

Cardoso, D. (2022) · theses.fr (ABES) · doi:10.70675/e5ce6d96z7253z4119zb119zc07f3977425d

Development of a novel PSC myogenic differentiation protocol to evaluate gene therapy for Duchenne Muscular Dystrophy in vitro

Akar, R. B. (2021) · theses.fr (ABES) · doi:10.70675/b84e7871zd711z4a82zb0aezbd7cd1039b09

Double‐Pronged NAD Preservation: Delaying Cellular Senescence and Initiating Musculoskeletal Regeneration

Yu, J., Hou, M., Deng, Y., Yu, C., Liu, Y., Kang, K., Xia, X., Li, X., Yang, H., Jiang, D., et al. (2026) · Aging Cell · doi:10.1111/acel.70468

Rewiring Glycolysis in Cancer: From Tumor Initiation to Therapeutic Vulnerabilities

Sun, S., Jia, L., Yu, Y., Jeong, S.-J., Zhang, Y., Ryu, D., & Ta, G. (2026) · Cells · doi:10.3390/cells15090771 · Cited by 1

Niacin accelerates skeletal muscle regeneration and enhances C2C12 differentiation by activating the PI3K/Akt signaling pathway

Dai, L., Wang, J., Zheyuan, C., Yu, T., Liu, J., Youchong, L., Zhang, Y., & Xiao, J. (2026) · Biochemical Pharmacology · doi:10.1016/j.bcp.2026.118016

Ion-coupled transfersome complexes for enhanced transdermal NAD+ repletion and mitigation of cellular senescence signatures

Kang, S., Wei, S., Koo, B. I., Jo, Y., Park, J., Xue, Y., Ye, S., Park, J., Hwang, B. W., Kim, J.-H., et al. (2026) · Materials Today Bio · doi:10.1016/j.mtbio.2026.103218 · Cited by 1

From NAD+ metabolism to skeletal muscle function: The emerging role of ADP-ribosylation

Yonamine, C. Y., Espino-González, E., Lozano, S. P. A., & Treebak, J. T. (2026) · Cell Reports · doi:10.1016/j.celrep.2026.117866

β‐hydroxy‐β‐methylbutyrate improves fast‐twitch muscle function, histopathology and mitochondrial respiration in the D2.mdx dystrophic mouse

Giourmas, N., Lalunio, H., Calzoni, M., Bagaric, R. M., Goodman, C. A., & Hayes, A. (2026) · The Journal of Physiology · doi:10.1113/jp291639

An NAD+-responsive adipose signal coordinates inter-organ defense against muscle atrophy

Liang, N., He, J., Guo, X., Yan, J., Zhang, X., Peng, X., & Li, J. (2026) · Cell Metabolism · doi:10.1016/j.cmet.2026.09.016

BindingDB Entry 50000368: α-Amino-β-carboxymuconate-ε-semialdehyde Decarboxylase (ACMSD) Inhibitors as Novel Modulators of De Novo Nicotinamide Adenine Dinucleotide (NAD

BindingDB (2019) · UC San Diego · doi:10.7270/q22j6f80

Replenishing NAD+ content reduces aspects of striated muscle disease in a dog model of Duchenne muscular dystrophy

Cardoso, D., Barthélémy, I., Blot, S., & Muchir, A. (2023) · Skeletal Muscle · doi:10.1186/s13395-023-00328-w · Cited by 6

Restoration of NAD + homeostasis protects C2C12 myoblasts and mouse levator ani muscle from mechanical stress-induced damage

Huang, G., He, Y., Li, H., Zhou, M., Zuo, X., & Zhao, Z. (2022) · Animal Cells and Systems · doi:10.1080/19768354.2022.2106303 · Cited by 7

Study of muscle regeneration in muscular dystrophies

Mechler, F., & Molnar, J. M. (1997) · Neuromuscular Disorders · doi:10.1016/s0960-8966(97)87352-x

277P Single-nuclei RNAseq in myotonic dystrophy type I: DMPK accumulation and myofiber repair

Todorow, V., Hayashi, S., Meinke, P., Schoser, B. G. H., & Nishino, I. (2024) · Neuromuscular Disorders · doi:10.1016/j.nmd.2024.07.095

RNA therapies are delivering as therapies for neuromuscular dystrophy patients: Editorial for the special issue on RNA therapies in Journal of Neuromuscular Diseases

Aartsma-Rus, A. M., & Takeda, S. (2025) · Journal of Neuromuscular Diseases · doi:10.1177/22143602251403854