Abdominal candidiasis is a hidden reservoir of echinocandin resistance

Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance

Magiorakos, A.-P., Srinivasan, A., Carey, R. B., Carmeli, Y., Falagas, M. E., Giske, C. G., Harbarth, S., Hindler, J. F., Kahlmeter, G., Olsson-Liljequist, B., et al. (2012) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2011.03570.x · Cited by 14,449 · see citing works

Clinical and Laboratory Standards Institute

Gressner, A. M., & Arndt, T. (2019) · Springer Reference Medizin · doi:10.1007/978-3-662-48986-4_300416 · Cited by 5,092 · see citing works

Impact of Treatment Strategy on Outcomes in Patients with Candidemia and Other Forms of Invasive Candidiasis: A Patient-Level Quantitative Review of Randomized Trials

Andes, D. R., Safdar, N., Baddley, J. W., Playford, G., Reboli, A. C., Rex, J. H., Sobel, J. D., Pappas, P. G., Kullberg, B. J., & for the Mycoses Study Group (2012) · Clinical Infectious Diseases · doi:10.1093/cid/cis021 · Cited by 793 · see citing works

Increasing Echinocandin Resistance in Candida glabrata: Clinical Failure Correlates With Presence of FKS Mutations and Elevated Minimum Inhibitory Concentrations

Alexander, B. D., Johnson, M. D., Pfeiffer, C. D., Jiménez-Ortigosa, C., Catania, J., Booker, R., Castanheira, M., Messer, S. A., Perlin, D. S., & Pfaller, M. A. (2013) · Clinical Infectious Diseases · doi:10.1093/cid/cit136 · Cited by 778 · see citing works

Defining Responses to Therapy and Study Outcomes in Clinical Trials of Invasive Fungal Diseases: Mycoses Study Group and European Organization for Research and Treatment of Cancer Consensus Criteria

Segal, B. H., Herbrecht, R., Stevens, D. A., Ostrosky‐Zeichner, L., Sobel, J. D., Viscoli, C., Walsh, T. J., Maertens, J. A., Patterson, T. F., Perfect, J. R., et al. (2008) · Clinical Infectious Diseases · doi:10.1086/590566 · Cited by 467 · see citing works

Interlaboratory variability of caspofungin MICs for Candida spp. using CLSI and EUCAST methods: Should the clinical laboratory be testing this agent?

Espinel-Ingroff, A., Arendrup, M. C., Pfaller, M. A., Bonfietti, L. X., Bustamante, B., Canton, E., Chryssanthou, E., Cuenca-Estrella, M., Dannaoui, E., Fothergill, A., et al. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01519-13 · Cited by 216 · see citing works

FKS Mutant Candida glabrata: Risk Factors and Outcomes in Patients With Candidemia

Beyda, N. D., John, J., Kilic, A., Alam, M. J., Lasco, T. M., & Garey, K. W. (2014) · Clinical Infectious Diseases · doi:10.1093/cid/ciu407 · Cited by 174 · see citing works

The Presence of an <i>FKS</i> Mutation Rather than MIC Is an Independent Risk Factor for Failure of Echinocandin Therapy among Patients with Invasive Candidiasis Due to Candida glabrata

Shields, R. K., Nguyen, M. H., Press, E. G., Kwa, A. L., Cheng, S., Du, C., & Clancy, C. J. (2012) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00027-12 · Cited by 171 · see citing works

Pharmacodynamics of Caspofungin in a Murine Model of Systemic Candidiasis: Importance of Persistence of Caspofungin in Tissues to Understanding Drug Activity

Louie, A., Deziel, M. R., Liu, W., Drusano, M. F., Gumbo, T., & Drusano, G. L. (2005) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.49.12.5058-5068.2005 · Cited by 163 · see citing works

Caspofungin MICs correlate with treatment outcomes among patients with Candida glabrata invasive candidiasis and prior echinocandin exposure.

Shields, R. K., Nguyen, M. H., Press, E. G., Updike, C. L., & Clancy, C. J. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00136-13 · Cited by 105 · see citing works

Real-world experience with echinocandin MICs against Candida species in a multicenter study of hospitals that routinely perform susceptibility testing of bloodstream isolates

Eschenauer, G. A., Nguyen, M. H., Shoham, S., Vazquez, J. A., Morris, A. J., Pasculle, W. A., Kubin, C. J., Klinker, K. P., Carver, P. L., Hanson, K. E., et al. (2014) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02163-13 · Cited by 61 · see citing works

Anidulafungin and Micafungin MIC Breakpoints Are Superior to That of Caspofungin for Identifying <i>FKS</i> Mutant Candida glabrata Strains and Echinocandin Resistance

Shields, R. K., Nguyen, M. H., Press, E. G., Updike, C. L., & Clancy, C. J. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01451-13 · Cited by 56 · see citing works

Candida Peritonitis: An Update on the Latest Research and Treatments

Carneiro, H. A., Mavrakis, A., & Mylonakis, E. E. (2011) · World Journal of Surgery · doi:10.1007/s00268-011-1305-2 · Cited by 55 · see citing works

Disposition of Caspofungin, a Novel Antifungal Agent, in Mice, Rats, Rabbits, and Monkeys

Sandhu, P., Xu, X., Bondiskey, P. J., Balani, S. K., Morris, M. L., Tang, Y. S., Miller, A. R., & Pearson, P. G. (2004) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.48.4.1272-1280.2004 · Cited by 49 · see citing works

Distribution of micafungin in the tissue fluids of patients with invasive fungal infections

Yamada, N., Kumada, K., Ogura, S., Kishino, S., Mochizuki, N., & Ohno, K. (2011) · Journal of Infection and Chemotherapy · doi:10.1007/s10156-011-0240-3 · Cited by 42 · see citing works

Undiagnosed invasive candidiasis: incorporating non-culture diagnostics into rational prophylactic and preemptive antifungal strategies

Clancy, C. J., & Nguyen, M. H. (2014) · Expert Review of Anti-infective Therapy · doi:10.1586/14787210.2014.919853 · Cited by 39 · see citing works

In Vitro Susceptibility of Breakthrough Candida Bloodstream Isolates Correlates with Daily and Cumulative Doses of Fluconazole

Clancy, C. J., Staley, B. J., & Nguyen, M. H. (2006) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00741-06 · Cited by 39 · see citing works

Candida glabrata Intra-Abdominal Candidiasis Is Characterized by Persistence within the Peritoneal Cavity and Abscesses

Cheng, S., Clancy, C. J., Hartman, D. J., Hao, B., & Nguyen, M. H. (2014) · Infection and Immunity · doi:10.1128/iai.00062-14 · Cited by 38 · see citing works

Treatment of Candidal Cholangitis with Caspofungin Therapy in a Patient with a Liver Transplant: Documentation of Biliary Excretion of Caspofungin

Goicoechea, M., Fierer, J., & Johns, S. T. (2004) · Clinical Infectious Diseases · doi:10.1086/382082 · Cited by 20 · see citing works

Invasive candidiasis

Kullberg, B. J., & Arendrup, M. C. (2015) · New England Journal of Medicine · doi:10.1056/nejmra1315399 · Cited by 1,315 · see citing works

The global problem of antifungal resistance: prevalence, mechanisms, and management

Perlin, D. S., Rautemaa-Richardson, R., & Alastruey-Izquierdo, A. (2017) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(17)30316-x · Cited by 1,055 · see citing works

Multidrug-Resistant Candida: Epidemiology, Molecular Mechanisms, and Treatment

Arendrup, M. C., & Patterson, T. F. (2017) · The Journal of Infectious Diseases · doi:10.1093/infdis/jix131 · Cited by 707 · see citing works

Candidemia and invasive candidiasis in adults: A narrative review

Antinori, S., Milazzo, L., Sollima, S., Galli, M., & Corbellino, M. (2016) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2016.06.029 · Cited by 259 · see citing works

Defining breakthrough invasive fungal infection–Position paper of the mycoses study group education and research consortium and the European Confederation of Medical Mycology

Cornely, O. A., Hoenigl, M., Lass‐Flörl, C., Chen, S. C. ‐., Kontoyiannis, D. P., Morrissey, C. O., & Thompson, G. R. (2019) · Mycoses · doi:10.1111/myc.12960 · Cited by 224 · see citing works

A multicenter multinational study of abdominal candidiasis: epidemiology, outcomes and predictors of mortality

Bassetti, M., Righi, E., Ansaldi, F., Merelli, M., Scarparo, C., Antonelli, M. M., Garnacho‐Montero, J., Díaz‐Martín, A., Palacios-García, I., Luzzati, R., et al. (2015) · Intensive Care Medicine · doi:10.1007/s00134-015-3866-2 · Cited by 210 · see citing works

Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)

Sartelli, M., Weber, D., Ruppé, É., Bassetti, M., Wright, B. J., Ansaloni, L., Catena, F., Coccolini, F., Abu‐Zidan, F. M., Coimbra, R. S. M., et al. (2016) · World Journal of Emergency Surgery · doi:10.1186/s13017-016-0089-y · Cited by 199 · see citing works

Rezafungin versus caspofungin for treatment of candidaemia and invasive candidiasis (ReSTORE): a multicentre, double-blind, double-dummy, randomised phase 3 trial

Thompson, G. R., Soriano, A., Cornely, O. A., Kullberg, B. J., Kollef, M., Vazquez, J., Honore, P. M., Bassetti, M., Pullman, J., Chayakulkeeree, M., et al. (2023) · The Lancet · doi:10.1016/s0140-6736(22)02324-8 · Cited by 192 · see citing works

Breakthrough invasive fungal infections: Who is at risk?

Jenks, J. D., Cornely, O. A., Chen, S. C. ‐., Thompson, G. R., & Hoenigl, M. (2020) · Mycoses · doi:10.1111/myc.13148 · Cited by 191 · see citing works

Emerging multidrug-resistant Candida species

Colombo, A. L., Júnior, J. N. D. A., & Guinea, J. (2017) · Current Opinion in Infectious Diseases · doi:10.1097/qco.0000000000000411 · Cited by 177 · see citing works

Update on Antifungal Drug Resistance

Perlin, D. S., Shor, E., & Zhao, Y. (2015) · Current Clinical Microbiology Reports · doi:10.1007/s40588-015-0015-1 · Cited by 174 · see citing works

Rezafungin versus caspofungin in a phase 2, randomized, double-blind study for the treatment of candidemia and invasive candidiasis: the STRIVE Trial

Thompson, G. R., Soriano, A., Skoutelis, A., Vazquez, J. A., Honore, P. M., Horcajada, J. P., Spapen, H., Bassetti, M., Ostrosky-Zeichner, L., Das, A. F., et al. (2021) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa1380 · Cited by 163 · see citing works

Intra-Abdominal Candidiasis: The Importance of Early Source Control and Antifungal Treatment

Vergidis, P., Clancy, C. J., Shields, R. K., Park, S. Y., Wildfeuer, B. N., Simmons, R. L., & Nguyen, M. H. (2016) · PLOS ONE · doi:10.1371/journal.pone.0153247 · Cited by 150 · see citing works

Molecular basis of antifungal drug resistance in yeasts

Morio, F., Jensen, R. H., Le Pape, P., & Arendrup, M. C. (2017) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2017.05.012 · Cited by 114 · see citing works

Treatment of Invasive Candidiasis: A Narrative Review

Ben-Ami, R. (2018) · Journal of Fungi · doi:10.3390/jof4030097 · Cited by 111 · see citing works

Unraveling drug penetration of echinocandin antifungals at the site of infection in an intra-abdominal abscess model

Zhao, Y., Prideaux, B., Nagasaki, Y., Lee, M. H., Chen, P.-Y., Blanc, L., Ho, H., Clancy, C. J., Nguyen, M. H., Dartois, V., et al. (2017) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01009-17 · Cited by 102 · see citing works

What has changed in the treatment of invasive candidiasis? A look at the past 10 years and ahead

Bassetti, M., Righi, E., Montravers, P., & Cornely, O. A. (2017) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkx445 · Cited by 101 · see citing works

Pan-Echinocandin-Resistant Candida glabrata Bloodstream Infection Complicating COVID-19: A Fatal Case Report

Posteraro, B., Torelli, R., Vella, A., Leone, P. M., Angelis, G. D., Carolis, E. D., Ventura, G., Sanguinetti, M., & Fantoni, M. (2020) · Journal of Fungi · doi:10.3390/jof6030163 · Cited by 97 · see citing works

Resistance to Antifungal Drugs

Ben‐Ami, R., & Kontoyiannis, D. P. (2021) · Infectious Disease Clinics of North America · doi:10.1016/j.idc.2021.03.003 · Cited by 101 · see citing works

Multicenter Study of Method-Dependent Epidemiological Cutoff Values for Detection of Resistance in Candida spp. and Aspergillus spp. to Amphotericin B and Echinocandins for the Etest Agar Diffusion Method

Espinel‐Ingroff, A., Arendrup, M. C., Cantón, R., Córdoba, S. B., Dannaoui, É., García‐Rodríguez, J., González, G. M., Govender, N. P., Martín‐Mazuelos, E., Lackner, M., et al. (2016) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01792-16 · Cited by 90 · see citing works

Posttreatment Antifungal Resistance among Colonizing Candida Isolates in Candidemia Patients: Results from a Systematic Multicenter Study

Jensen, R. H., Johansen, H. K., Søes, L. M., Lemming, L. E., Rosenvinge, F. S., Nielsen, L., Olesen, B., Kristensen, L., Dzajic, E., Astvad, K. M. T., et al. (2016) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01763-15 · Cited by 77 · see citing works

Epidemiology of antifungal resistance in human pathogenic yeasts: current viewpoint and practical recommendations for management

Farmakiotis, D., & Kontoyiannis, D. P. (2017) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2017.05.019 · Cited by 76 · see citing works

Clinical perspectives on echinocandin resistance among Candida species

Shields, R. K., Nguyen, M. H., & Clancy, C. J. (2015) · Current Opinion in Infectious Diseases · doi:10.1097/qco.0000000000000215 · Cited by 75 · see citing works

Multicenter Study of Epidemiological Cutoff Values and Detection of Resistance in Candida spp. to Anidulafungin, Caspofungin, and Micafungin Using the Sensititre YeastOne Colorimetric Method

Espinel‐Ingroff, A., Álvarez-Fernández, M., Cantón, R., Carver, P. L., Chen, S. C. A., Eschenauer, G. A., Getsinger, D., González, G. M., Govender, N. P., Grancini, A., et al. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01250-15 · Cited by 67 · see citing works

Caspofungin: Pharmacodynamics, pharmacokinetics, clinical uses and treatment outcomes

Song, J., & Stevens, D. A. (2015) · Critical Reviews in Microbiology · doi:10.3109/1040841x.2015.1068271 · Cited by 62 · see citing works

Invasive fungal infections in acute and chronic liver impairment: A systematic review

Lahmer, T., Pietrobom, P. M. P., Schmid, R. M., & Colombo, A. L. (2021) · Mycoses · doi:10.1111/myc.13403 · Cited by 56 · see citing works

Invasive Fungal Infections in Patients with Hematological Malignancies: Emergence of Resistant Pathogens and New Antifungal Therapies

Gamaletsou, M. N., Walsh, T. J., & Sipsas, N. V. (2018) · Turkish Journal of Hematology · doi:10.4274/tjh.2018.0007 · Cited by 56 · see citing works

Rate of<i>FKS</i>Mutations among Consecutive Candida Isolates Causing Bloodstream Infection

Shields, R. K., Nguyen, M. H., Press, E. G., Cumbie, R., Driscoll, E., Pasculle, A. W., & Clancy, C. J. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01973-15 · Cited by 55 · see citing works

Management of intra-abdominal infections: recommendations by the Italian council for the optimization of antimicrobial use

Sartelli, M., Tascini, C., Coccolini, F., Dellai, F., Ansaloni, L., Antonelli, M. M., Bartoletti, M., Bassetti, M., Boncagni, F., Carlini, M., et al. (2024) · World Journal of Emergency Surgery · doi:10.1186/s13017-024-00551-w · Cited by 62 · see citing works

Invasive Candida Infections in Liver Transplant Recipients: Clinical Features and Risk Factors for Mortality

Bassetti, M., Peghin, M., Carnelutti, A., Righi, E., Merelli, M., Ansaldi, F., Trucchi, C., Alicino, C., Sartor, A., Wauters, J., et al. (2017) · Transplantation Direct · doi:10.1097/txd.0000000000000673 · Cited by 54 · see citing works

Spontaneous Mutational Frequency and FKS Mutation Rates Vary by Echinocandin Agent against Candida glabrata

Shields, R. K., Kline, E. G., Healey, K. R., Kordalewska, M., Perlin, D. S., Nguyen, M. H., & Clancy, C. J. (2018) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01692-18 · Cited by 50 · see citing works

Deciphering the epidemiology of invasive candidiasis in the intensive care unit: is it possible?

Soulountsi, V., Schizodimos, T., & Kotoulas, S. (2021) · Infection · doi:10.1007/s15010-021-01640-7 · Cited by 50 · see citing works

Imaging and spatially resolved quantification of drug distribution in tissues by mass spectrometry

Prideaux, B., Lenaerts, A. J. M., & Dartois, V. A. (2018) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2018.05.007 · Cited by 45 · see citing works

Echinocandin Resistance in Candida Species Isolates from Liver Transplant Recipients

Prigent, G., Aït‐Ammar, N., Levesque, É., Fekkar, A., Costa, J., Anbassi, S. E., Foulet, F., Duvoux, C., Merle, J., Dannaoui, É., et al. (2016) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01229-16 · Cited by 44 · see citing works

Clinical and Laboratory Development of Echinocandin Resistance in Candida glabrata: Molecular Characterization

Rivero-Menéndez, O., Navarro-Rodríguez, P., Bernal‐Martínez, L., Martin-Cano, G., Lopez-Perez, L., Sánchez‐Romero, I., Pérez‐Ayala, A., Capilla, J., Zaragoza, Ó., & Alastruey‐Izquierdo, A. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.01585 · Cited by 45 · see citing works

Echinocandin Resistance in Candida Species: a Review of Recent Developments

Wiederhold, N. P. (2016) · Current Infectious Disease Reports · doi:10.1007/s11908-016-0549-2 · Cited by 41 · see citing works

Antifungal susceptibility testing in Candida, Aspergillus and Cryptococcus infections: are the MICs useful for clinicians?

Bassetti, M., Vena, A., Bouza, E., Peghin, M., Muñoz, P., Righi, E., Pea, F., Lackner, M., & Lass-Flörl, C. (2020) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2020.02.017 · Cited by 40 · see citing works

Intra-abdominal infections survival guide: a position statement by the Global Alliance For Infections In Surgery

Sartelli, M., Barie, P. S., Agnoletti, V., Al‐Hasan, M. N., Ansaloni, L., Biffl, W. L., Buonomo, L. A., Blot, S. I., Cheadle, W. G., Coimbra, R. S. M., et al. (2024) · World Journal of Emergency Surgery · doi:10.1186/s13017-024-00552-9 · Cited by 51 · see citing works

Pharmacokinetics of echinocandins in suspected candida peritonitis: A potential risk for resistance

Gioia, F., Gómez‐López, A., Alvarez, M. E., de la Pedrosa, E. G., Martín‐Dávila, P., Cuenca‐Estrella, M., Moreno, S., & Fortün, J. (2020) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2020.09.019 · Cited by 40 · see citing works

Antifungal therapy for patients with proven or suspected Candida peritonitis: Amarcand2, a prospective cohort study in French intensive care units

Montravers, P., Pérrigault, P.-F., Timsit, J., Mira, J. P., Lortholary, O., Leroy, O., Gangneux, J., Guillemot, D., Bensoussan, C., Bailly, S., et al. (2016) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2016.10.001 · Cited by 39 · see citing works

The Role of Novel Antifungals in the Management of Candidiasis: A Clinical Perspective

Ordaya, E. E., Clement, J., & Vergidis, P. I. (2023) · Mycopathologia · doi:10.1007/s11046-023-00759-5 · Cited by 37 · see citing works

Critical appraisal beyond clinical guidelines for intraabdominal candidiasis

Maseda, E., Martín‐Loeches, I., Zaragoza, R., Pemán, J., Fortün, J., Grau, S., Aguilar, G., Varela, M., Borges-Sa, M., Giménez, M.-J., et al. (2023) · Critical Care · doi:10.1186/s13054-023-04673-6 · Cited by 35 · see citing works

How urgent is the need for new antifungals?

Stewart, A. G., & Paterson, D. L. (2021) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2021.1935868 · Cited by 36 · see citing works

Invasive Fungal Infections after Liver Transplantation

Senoner, T., Breitkopf, R., Treml, B., & Rajšić, S. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12093238 · Cited by 31 · see citing works

In Vitro Exposure to Increasing Micafungin Concentrations Easily Promotes Echinocandin Resistance in Candida glabrata Isolates

Bordallo-Cardona, M. Á., Escribano, P., de la Pedrosa, E. G. G., Marcos-Zambrano, L. J., Cantón, R., Bouza, E., & Guinea, J. (2016) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01542-16 · Cited by 32 · see citing works

Beyond Conventional Antifungals: Combating Resistance Through Novel Therapeutic Pathways

Hetta, ‏. F., Melhem, T., Aljohani, H. M., Salama, A., Ahmed, R., Elfadil, H., Alanazi, F. E., Ramadan, Y. N., Battah, B., Rottura, M., et al. (2025) · Pharmaceuticals · doi:10.3390/ph18030364 · Cited by 31 · see citing works

Essentials in Candida bloodstream infection

Mellinghoff, S. C., Cornely, O. A., & Jung, N. (2018) · Infection · doi:10.1007/s15010-018-1218-1 · Cited by 29 · see citing works

Antifungal Susceptibility Testing Identifies the Abdominal Cavity as a Source of Candida glabrata-Resistant Isolates

Díaz-García, J., Mesquida, A., Gómez, A., Machado, M., Martín-Rabadán, P., Alcalá, L., Sánchez-Carrillo, C., Reigadas, E., Vicente, T., Muñoz, P., et al. (2021) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01249-21 · Cited by 27 · see citing works

Penetration of Ibrexafungerp (Formerly SCY-078) at the Site of Infection in an Intra-abdominal Candidiasis Mouse Model

Lee, A., Prideaux, B., Zimmerman, M., Carter, C. L., Barat, S., Angulo, D. A., Dartois, V. A., Perlin, D. S., & Zhao, Y. (2019) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02268-19 · Cited by 26 · see citing works

Beyond tissue concentrations: antifungal penetration at the site of infection

Zhao, Y., Prideaux, B., Baistrocchi, S. R., Sheppard, D. C., & Perlin, D. S. (2018) · Medical Mycology · doi:10.1093/mmy/myy067 · Cited by 23 · see citing works

Anidulafungin Susceptibility Testing of Candida glabrata Isolates from Blood Cultures by the MALDI Biotyper Antibiotic (Antifungal) Susceptibility Test Rapid Assay

Vatanshenassan, M., Arastehfar, A. A., Boekhout, T., Berman, J. G., Lass‐Flörl, C., Sparbier, K., & Kostrzewa, M. (2019) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00554-19 · Cited by 21 · see citing works

Echinocandin resistance among Candida isolates at an academic medical centre 2005–15: analysis of trends and outcomes

McCarty, T. P., Lockhart, S. R., Moser, S. A., Whiddon, J., Zurko, J., Pham, C. D., & Pappas, P. G. (2018) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dky059 · Cited by 21 · see citing works

Mutant Prevention Concentration and Mutant Selection Window of Micafungin and Anidulafungin in Clinical Candida glabrata Isolates

Bordallo-Cardona, M. Á., Marcos-Zambrano, L. J., Sánchez‐Carrillo, C., de la Pedrosa, E. G. G., Cantón, R., Bouza, E., Escribano, P., & Guinea, J. (2018) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01982-17 · Cited by 21 · see citing works

Pharmacokinetic and pharmacodynamic considerations for antifungal therapy optimisation in the treatment of intra-abdominal candidiasis

Novy, E., Roger, C., Roberts, J. A., & Cotta, M. O. (2023) · Critical Care · doi:10.1186/s13054-023-04742-w · Cited by 21 · see citing works

Caspofungin Population Pharmacokinetic Analysis in Plasma and Peritoneal Fluid in Septic Patients with Intra-Abdominal Infections: A Prospective Cohort Study

Garbez, N., Mbatchi, L., Wallis, S. C., Müller, L., Lipman, J., Roberts, J. A., Lefrant, J., & Roger, C. (2021) · Clinical Pharmacokinetics · doi:10.1007/s40262-021-01062-6 · Cited by 20 · see citing works

Mind the gaps: challenges in the clinical management of invasive candidiasis in critically ill patients

Pietrobom, P. M. P., & Colombo, A. L. (2020) · Current Opinion in Infectious Diseases · doi:10.1097/qco.0000000000000684 · Cited by 20 · see citing works

Therapeutic Potential of Fosmanogepix (APX001) for Intra-abdominal Candidiasis: from Lesion Penetration to Efficacy in a Mouse Model

Lee, A., Wang, N., Carter, C. L., Zimmerman, M., Dartois, V. A., Shaw, K. J., Perlin, D. S., & Zhao, Y. (2021) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02476-20 · Cited by 20 · see citing works

Breakthrough invasive fungal infection after liver transplantation in patients on targeted antifungal prophylaxis: A prospective multicentre study

Rinaldi, M., Bartoletti, M., Ferrarese, A., Franceschini, E., Campoli, C., Coladonato, S., Pascale, R., Tedeschi, S., Gatti, M., Cricca, M., et al. (2021) · Transplant Infectious Disease · doi:10.1111/tid.13608 · Cited by 20 · see citing works

Current recommendations and importance of antifungal stewardship for the management of invasive candidiasis

Miyazaki, T., & Kohno, S. (2015) · Expert Review of Anti-infective Therapy · doi:10.1586/14787210.2015.1058157 · Cited by 18 · see citing works

Jávea consensus guidelines for the treatment of Candida peritonitis and other intra-abdominal fungal infections in non-neutropenic critically ill adult patients

Pemán, J., Aguilar, G., Valía, J. C., Salavert, M., Navarro, D., & Zaragoza, R. (2017) · Revista Iberoamericana de Micología · doi:10.1016/j.riam.2016.12.001 · Cited by 18 · see citing works

Prospective Cohort Study of Micafungin Population Pharmacokinetic Analysis in Plasma and Peritoneal Fluid in Septic Patients with Intra-abdominal Infections

Garbez, N., Mbatchi, L., Wallis, S. C., Müller, L., Lipman, J., Roberts, J. A., Lefrant, J., & Roger, C. (2021) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02307-20 · Cited by 17 · see citing works

Commercial Methods for Antifungal Susceptibility Testing of Yeasts: Strengths and Limitations as Predictors of Resistance

Espinel‐Ingroff, A. (2022) · Journal of Fungi · doi:10.3390/jof8030309 · Cited by 19 · see citing works

Low and constant micafungin concentrations may be sufficient to lead to resistance mutations in FKS2 gene of Candida glabrata

Bordallo-Cardona, M. Á., Escribano, P., Marcos-Zambrano, L. J., Díaz-García, J., de la Pedrosa, E. G. G., Cantón, R., Bouza, E., & Guinea, J. (2017) · Medical Mycology · doi:10.1093/mmy/myx124 · Cited by 16 · see citing works

Liposomal amphotericin B—the future

Hoenigl, M., Lewis, R. E., van de Veerdonk, F. L., Verweij, P. E., & Cornely, O. A. (2022) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkac353 · Cited by 17 · see citing works

Virulence and susceptibility patterns of clinical Candida spp. isolates from a tertiary hospital, Tanzania

Mushi, M. F., Bader, O., Bii, C. C., Groß, U., & Mshana, S. E. (2018) · Medical Mycology · doi:10.1093/mmy/myy107 · Cited by 16 · see citing works

In Vivo Efficacy of Rezafungin, Anidulafungin, Caspofungin, and Micafungin against Four Candida auris Clades in a Neutropenic Mouse Bloodstream Infection Model

Balázsi, D., Tóth, Z., Locke, J. B., Borman, A. M., Forgács, L., Balla, N., Kovács, F., Kovács, R., Amano, C., Baran, T. I., et al. (2024) · Journal of Fungi · doi:10.3390/jof10090617 · Cited by 15 · see citing works

A Narrative Review of Invasive Candidiasis in the Intensive Care Unit

Noppè, E., Eloff, J. R. P., Keane, S., & Martín‐Loeches, I. (2024) · Therapeutic Advances in Pulmonary and Critical Care Medicine · doi:10.1177/29768675241304684 · Cited by 15 · see citing works

Breakthrough invasive fungal infections in liver transplant recipients exposed to prophylaxis with echinocandins vs other antifungal agents: A systematic review and meta‐analysis

Gatti, M., Rinaldi, M., Ferraro, G., Toschi, A., Caroccia, N., Arbizzani, F., Raschi, E., Poluzzi, E., Pea, F., Viale, P., et al. (2021) · Mycoses · doi:10.1111/myc.13362 · Cited by 13 · see citing works

Antifungal resistance in Candida spp within the intra-abdominal cavity: study of resistance acquisition in patients with serial isolates

Díaz-García, J., Machado, M., Alcalá, L., Reigadas, E., Sánchez‐Carrillo, C., Pérez‐Ayala, A., de la Pedrosa, E. G., González‐Romo, F., Merino, P., Cuétara, M. S., et al. (2023) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2023.08.021 · Cited by 13 · see citing works

Tolerability of pulsed high-dose L-AmB as pre-emptive therapy in patients at high risk for intra-abdominal candidiasis: A phase 2 study (LAMBDA study)

Rinaldi, M., Bartoletti, M., Bonazzetti, C., Caroccia, N., Gatti, M., Tazza, B., Horna, C. S., Giannella, M., & Viale, P. (2023) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2023.106998 · Cited by 13 · see citing works

Case Report: Echinocandin-Resistance Candida glabrata FKS Mutants From Patient Following Radical Cystoprostatectomy Due to Muscle-Invasive Bladder Cancer

Szymankiewicz, M., Kamecki, K., Jarzynka, S., Koryszewska-Bagińska, A., Olędzka, G., & Nowikiewicz, T. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.794235 · Cited by 13 · see citing works

Evolutionary dynamics in gut-colonizing Candida glabrata during caspofungin therapy: Emergence of clinically important mutations in sphingolipid biosynthesis

Hassoun, Y., Aptekmann, A. A., Keniya, M. V., Gomez, R. Y., Alayo, N., Novi, G., Quinteros, C., Kaya, F., Zimmerman, M. D., Caceres, D. H., et al. (2024) · PLoS Pathogens · doi:10.1371/journal.ppat.1012521 · Cited by 11 · see citing works

Resistance to Echinocandins Complicates a Case of Candida albicans Bloodstream Infection: A Case Report

Trovato, L., Bongiorno, D., Calvo, M., Migliorisi, G., Borraccino, A., Musso, N., Oliveri, S. M., Stefani, S., & Scalia, G. (2021) · Journal of Fungi · doi:10.3390/jof7060405 · Cited by 11 · see citing works

Bring it on: Top five antimicrobial stewardship challenges in transplant infectious diseases and practical strategies to address them

So, M., Tsai, H., Swaminathan, N., & Bartash, R. M. (2022) · Antimicrobial Stewardship & Healthcare Epidemiology · doi:10.1017/ash.2022.53 · Cited by 11 · see citing works

Invasive Fungal Breakthrough Infections under Targeted Echinocandin Prophylaxis in High-Risk Liver Transplant Recipients

Breitkopf, R., Treml, B., Senoner, T., Bukumirić, Z., & Rajšić, S. (2023) · Journal of Fungi · doi:10.3390/jof9020272 · Cited by 13 · see citing works

Current Trends in Candidiasis

Uppuluri, P., Khan, A. A., & Edwards, J. E. (2017) · Springer eBooks · doi:10.1007/978-3-319-50409-4_2 · Cited by 14 · see citing works

Mechanisms of multidrug resistance caused by an Ipi1 mutation in the fungal pathogen Candida glabrata

Miyazaki, T., Shimamura, S., Nagayoshi, Y., Nakayama, H., Morita, A., Tanaka, Y., Matsumoto, Y., Inamine, T., Nishikawa, H., Nakada, N., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-56269-z · Cited by 10 · see citing works

Early use of the novel antifungal rezafungin: a case series and literature review

Davidson, H., Yau, T. Y., Dunstan, I., Houston, A., Basarab, M., & Bicanic, T. A. (2025) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkaf143 · Cited by 10 · see citing works

Detection of Echinocandin-Resistant Candida glabrata in Blood Cultures Spiked with Different Percentages of FKS2 Mutants

Bordallo-Cardona, M. Á., Sánchez‐Carrillo, C., Bouza, E., Muñóz, P., Escribano, P., & Guinea, J. (2018) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02004-18 · Cited by 10 · see citing works

Rezafungin acetate for the treatment of candidemia and invasive candidiasis: a pharmacokinetic evaluation

Bassetti, M., Stewart, A. G., Bartalucci, C., Vena, A., Giacobbe, D. R., & Roberts, J. A. (2024) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1080/17425255.2024.2424899 · Cited by 9 · see citing works

Empiric Antifungal Therapy for Intra-Abdominal Post-Surgical Abscesses in Non-ICU Patients

Taddei, E., Giovannenze, F., Birocchi, E., Murri, R., Cerolini, L., Segala, F. V., Vecchio, P. D., Taccari, F., & Fantoni, M. (2023) · Antibiotics · doi:10.3390/antibiotics12040701 · Cited by 7 · see citing works

A Child With COVID-19, Type 1 Diabetes, and Candida glabrata : A Case Report and Literature Review

Brothers, E. M., Lidsky, K. B., Simmons, J., & Nakagawa, T. A. (2021) · Clinical Pediatrics · doi:10.1177/00099228211052471 · Cited by 7 · see citing works

Pharmacokinetics/Pharmacodynamics of Caspofungin in Plasma and Peritoneal Fluid of Liver Transplant Recipients

Pressiat, C., Aït‐Ammar, N., Daniel, M., Lesne-Hulin, A., Botterel, F., & Levesque, É. (2021) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01187-21 · Cited by 7 · see citing works

Invasive Fungal Infections: The Early Killer after Liver Transplantation

Breitkopf, R., Treml, B., Bukumirić, Z., Innerhofer, N., Fodor, M., & Rajšić, S. (2023) · Journal of Fungi · doi:10.3390/jof9060655 · Cited by 7 · see citing works

Efficacy of humanized single large doses of caspofungin on the lethality and fungal tissue burden in a deeply neutropenic murine model against Candida albicans and Candida dubliniensis

Prépost, E., Tóth, Z., Perlin, D. S., Gesztelyi, R., Kardos, G., Kovács, R., Nagy, F., Forgács, L., & Majoros, L. (2019) · Infection and Drug Resistance · doi:10.2147/idr.s198764 · Cited by 6 · see citing works

Comparison of Killing Activity of Micafungin Against Six Candida Species Isolated from Peritoneal and Pleural Cavities in RPMI-1640, 10 and 30% Serum

Tóth, Z., Kardos, T., Kovács, R., Kardos, G., Nagy, F., Prépost, E., Barta, Z., Takács, I., & Majoros, L. (2018) · Mycopathologia · doi:10.1007/s11046-018-0302-5 · Cited by 5 · see citing works

Personalized Approaches to Patients with Intra-Abdominal Infections

Sartelli, M., Coccolini, F., Labricciosa, F. M., Siquini, W., Pipitone, G., Palmieri, M., Sbacco, V., Vallicelli, C., Marmorale, C., & Catena, F. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14217774 · Cited by 4 · see citing works

Risk Factors and Outcomes of Invasive Candida Infections in Heart Transplant Recipients: A Case‐Control Study

Alsoubani, M., Vazquez, G. A., Strand, A. M., Doron, S., & Chow, J. K. L. (2025) · Clinical Transplantation · doi:10.1111/ctr.70091 · Cited by 4 · see citing works

Invasive Candida in the abdomen: how to differentiate infection from colonization

Deckers, C., Montesinos, I., Plum, P. E., Bassetti, M., & Honoré, P. M. (2025) · Expert Review of Anti-infective Therapy · doi:10.1080/14787210.2025.2516553 · Cited by 4 · see citing works

BASES DA RESISTÊNCIA ANTIFÚNGICA: UMA REVISÃO COMENTADA

Berto, C., Wirth, F., Barth, N., & Hermes, D. M. (2018) · Revista Uningá · doi:10.46311/2318-0579.55.euj773 · Cited by 4 · see citing works

Killing Activity of Micafungin Against Candida albicans, C. dubliniensis and Candida africana in the Presence of Human Serum

Kovács, R., Saleh, Q., Bozó, A., Tóth, Z., Gesztelyi, R., Kardos, T., Kardos, G., Takács, I., & Majoros, L. (2017) · Mycopathologia · doi:10.1007/s11046-017-0178-9 · Cited by 4 · see citing works

Evaluation of Candida peritonitis with underlying peritoneal fibrosis and efficacy of micafungin in murine models of intra-abdominal candidiasis

Ashizawa, N., Miyazaki, T., Abe, S., Takazono, T., Saijo, T., Obata, Y., Shimamura, S., Yamamoto, K., Imamura, Y., Koji, T., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-45776-x · Cited by 4 · see citing works

Evolution in the Management of Invasive Fungal Infections in Liver Transplant Recipients

Verma, A., Weigel, K., Dexter, S. Y. K., & Dhawan, A. K. (2018) · OBM Transplantation · doi:10.21926/obm.transplant.1802009 · Cited by 3 · see citing works

Diagnosis and Management of Invasive Candida Infections in Critically Ill Patients

Zakhem, A. E., Istambouli, R., Jabbour, J.-F., Hindy, J.-R., Gharamti, A. A., & Kanj, S. S. (2022) · Seminars in Respiratory and Critical Care Medicine · doi:10.1055/s-0041-1741009 · Cited by 3 · see citing works

Clinical outcomes and risk factors of invasive candidiasis in patients with infected pancreatic necrosis

Liu, T., & Li, G. (2025) · Pancreatology · doi:10.1016/j.pan.2025.09.019 · Cited by 2 · see citing works

Emerging of Fatal Colitis with Multidrug-Resistant Candida glabrata after Small Bowel Transplantation

Zareshahrabadi, Z., Shafiekhani, M., Nikoupour, H., Nouraei, H., Morovati, H., & Zomorodian, K. (2021) · Case Reports in Transplantation · doi:10.1155/2021/9995583 · Cited by 2 · see citing works

BASES DA RESISTÊNCIA ANTIFÚNGICA: UMA REVISÃO COMENTADA

Berto, C., & Hermes, D. M. (2023) · Editora Científica Digital eBooks · doi:10.37885/221211599 · Cited by 2 · see citing works

Temporal changes in fungal epidemiology in ICU post-operative peritonitis cases

Montravers, P., Bonnal, C., Andrei, S., Augustin, P., Grall, N., & Zappella, N. (2025) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-025-05314-2 · Cited by 1 · see citing works

Resistenz bei Pilzen

Vehreschild, M. J. G. T., & Cornely, O. A. (2015) · Der Internist · doi:10.1007/s00108-015-3704-1 · Cited by 1 · see citing works

Update on the management of intra-abdominal Candida infections

Calabuig, E., Camarena, J. J., & Carbonell, N. (2017) · Revista Iberoamericana de Micología · doi:10.1016/j.riam.2017.02.005 · Cited by 1 · see citing works

FKS Mutant Candida glabrata: Risk Factors and Outcomes in Patients With Candidemia

Beyda, N. D., John, J., Kilic, A., Alam, M. J., Lasco, T. M., & Garey, K. W. (2014) · Clinical Infectious Diseases · doi:10.1093/cid/ciu407 · Cited by 174 · see citing works

Emerging echinocandin-resistant Candida albicans and glabrata in Switzerland

Coste, A. T., Kritikos, A., Li, J., Khanna, N., Goldenberger, D., Garzoni, C., Zehnder, C., Boggian, K., Neofytos, D., Riat, A., et al. (2020) · Infection · doi:10.1007/s15010-020-01475-8 · Cited by 69 · see citing works

Increasing Echinocandin Resistance in Candida glabrata: Clinical Failure Correlates With Presence of FKS Mutations and Elevated Minimum Inhibitory Concentrations

Alexander, B. D., Johnson, M. D., Pfeiffer, C. D., Jiménez-Ortigosa, C., Catania, J., Booker, R., Castanheira, M., Messer, S. A., Perlin, D. S., & Pfaller, M. A. (2013) · Clinical Infectious Diseases · doi:10.1093/cid/cit136 · Cited by 778 · see citing works

Candida glabrata FKS1 and FKS2 Mutations are Linked to Echinocandin Resistance

Perlin, D. S. (2008) · 46th Annual Meeting

Candida albicans and Candida glabrata Clinical Isolates Exhibiting Reduced Echinocandin Susceptibility

Katiyar, S. K., Pfaller, M. A., & Edlind, T. D. (2006) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00349-06 · Cited by 189 · see citing works