Macrophage Proresolving Mediators—the When and Where

Cytokine-mediated regulation of CXCR4 expression in human neutrophils

Nagase, H., Miyamasu, M., Yamaguchi, M., Imanishi, M., Tsuno, N. H., Matsushima, K., Yamamoto, K., Morita, Y., & Hirai, K. (2002) · Journal of Leukocyte Biology · doi:10.1189/jlb.71.4.711 · Cited by 4,713 · see citing works

Pathologic Basis of Disease.

(1980) · Annals of Internal Medicine · doi:10.7326/0003-4819-92-3-460_4 · Cited by 4,593 · see citing works

Pro-resolving lipid mediators are leads for resolution physiology

Serhan, C. N. (2014) · Nature · doi:10.1038/nature13479 · Cited by 3,041 · see citing works

Resolution of inflammation: the beginning programs the end

Serhan, C. N., & Savill, J. (2005) · Nature Immunology · doi:10.1038/ni1276 · Cited by 2,552 · see citing works

Leukotrienes and Lipoxins: Structures, Biosynthesis, and Biological Effects

Samuelsson, B. O., Dahlén, S., LINDGREN, J. Å., Rouzer, C. A., & Serhan, C. N. (1987) · Science · doi:10.1126/science.2820055 · Cited by 2,233 · see citing works

Nonresolving Inflammation

Nathan, C., & Ding, A. (2010) · Cell · doi:10.1016/j.cell.2010.02.029 · Cited by 2,183 · see citing works

Robbins pathologic basis of disease

Cotran, R. S., Kumar, V., & Collins, T. (1989) · Medical Entomology and Zoology · Cited by 1,944 · see citing works

The Nature and Significance of Platelet Products in Human Plasma

Wolf, P. (1967) · British Journal of Haematology · doi:10.1111/j.1365-2141.1967.tb08741.x · Cited by 1,725 · see citing works

The Human Serum Metabolome

Psychogios, N., Hau, D., Peng, J., Guo, A. C., Mandal, R., Bouatra, S., Sinelnikov, I. V., Krishnamurthy, R., Eisner, R., Gautam, B., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016957 · Cited by 1,718 · see citing works

Resolvins

Serhan, C. N., Hong, S., Gronert, K., Colgan, S. P., Devchand, P. R., Mirick, G., & Moussignac, R.-L. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20020760 · Cited by 1,650 · see citing works

Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages.

Savill, J. S., Wyllie, A. H., Henson, J. E., Walport, M. J., Henson, P. M., & Haslett, C. (1989) · Journal of Clinical Investigation · doi:10.1172/jci113970 · Cited by 1,536 · see citing works

Lipid mediator class switching during acute inflammation: signals in resolution

Levy, B. D., Clish, C. B., Schmidt, B., Gronert, K., & Serhan, C. N. (2001) · Nature Immunology · doi:10.1038/89759 · Cited by 1,453 · see citing works

Detection of microRNA Expression in Human Peripheral Blood Microvesicles

Hunter, M. P., Ismail, N., Zhang, X., Aguda, B. D., Lee, E. J., Yu, L., Xiao, T., Schafer, J., Lee, M. T., Schmittgen, T. D., et al. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003694 · Cited by 1,453 · see citing works

Novel Functional Sets of Lipid-Derived Mediators with Antiinflammatory Actions Generated from Omega-3 Fatty Acids via Cyclooxygenase 2–Nonsteroidal Antiinflammatory Drugs and Transcellular Processing

Serhan, C. N., Clish, C. B., Brannon, J., Colgan, S. P., Chiang, N., & Gronert, K. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.8.1197 · Cited by 1,189 · see citing works

Resolvin E1 and protectin D1 activate inflammation-resolution programmes

Schwab, J. M., Chiang, N., Arita, M., & Serhan, C. N. (2007) · Nature · doi:10.1038/nature05877 · Cited by 1,188 · see citing works

Emerging targets in neuroinflammation-driven chronic pain

Ji, R., Xu, Z., & Gao, Y. (2014) · Nature Reviews Drug Discovery · doi:10.1038/nrd4334 · Cited by 1,102 · see citing works

Anti-inflammatory Agents: Present and Future

Dinarello, C. A. (2010) · Cell · doi:10.1016/j.cell.2010.02.043 · Cited by 1,095 · see citing works

Platelets Amplify Inflammation in Arthritis via Collagen-Dependent Microparticle Production

Boilard, É., Nigrovic, P. A., Larabee, K. S., Watts, G. F. M., Coblyn, J. S., Weinblatt, M. E., Massarotti, E. M., Remold‐O’Donnell, E., Farndale, R. W., Ware, J. L., et al. (2010) · Science · doi:10.1126/science.1181928 · Cited by 1,088 · see citing works

Resolution of in flammation: state of the art, definitions and terms

Serhan, C. N., Brain, S. D., Buckley, C. D., Gilroy, D. W., Haslett, C., O'Neill, L. A. J., Perretti, M., Rossi, A. G., & Wallace, J. L. (2007) · The FASEB Journal · doi:10.1096/fj.06-7227rev · Cited by 1,045 · see citing works

Resolvins and protectins in inflammation resolution

Serhan, C. N., & Petasis, N. A. (2011) · Chemical Reviews · doi:10.1021/cr100396c · Cited by 996 · see citing works

Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo

Lämmermann, T., Afonso, P. V., Angermann, B., Wang, J. M., Kastenmüller, W., Parent, C. A., & Germain, R. N. (2013) · Nature · doi:10.1038/nature12175 · Cited by 937 · see citing works

Maresins: Novel macrophage mediators with potent antiinflammatory and proresolving actions

Serhan, C. N., Yang, R., Martinod, K., Kasuga, K., Pillai, P. S., Porter, T. F., Oh, S. F., & Spite, M. (2009) · Journal of Experimental Medicine · doi:10.1084/jem.20081880 · Cited by 908 · see citing works

Proresolving Lipid Mediators and Mechanisms in the Resolution of Acute Inflammation

Buckley, C. D., Gilroy, D. W., & Serhan, C. N. (2014) · Immunity · doi:10.1016/j.immuni.2014.02.009 · Cited by 811 · see citing works

Molecular Circuits of Resolution: Formation and Actions of Resolvins and Protectins

Bannenberg, G. L., Chiang, N., Ariel, A., Arita, M., Tjonahen, E., Gotlinger, K. H., Hong, S., & Serhan, C. N. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.7.4345 · Cited by 699 · see citing works

The macrophage: Past, present and future

Gordon, S. (2007) · European Journal of Immunology · doi:10.1002/eji.200737638 · Cited by 625 · see citing works

Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: A mechanism for cellular human immunodeficiency virus 1 infection

Mack, M., Kleinschmidt, A., Brühl, H., Klier, C. M., Nelson, P. J., Cihak, J., Plachý, J., Stangassinger, M., Erfle, V., & Schlöndorff, D. (2000) · Nature Medicine · doi:10.1038/77498 · Cited by 605 · see citing works

Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain

Serhan, C. N., Dalli, J., Karamnov, S., Choi, A. J. S., Park, C., Xu, Z., Ji, R., Zhu, M., & Petasis, N. A. (2012) · The FASEB Journal · doi:10.1096/fj.11-201442 · Cited by 596 · see citing works

Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections

Tobin, D. M., Roca, F. J., Oh, S. F., McFarland, R., Vickery, T. W., Ray, J. P., Ko, D. C., Zou, Y., Bang, N. D., Chau, T. T. H., et al. (2012) · Cell · doi:10.1016/j.cell.2011.12.023 · Cited by 576 · see citing works

Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators

Dalli, J., & Serhan, C. N. (2012) · Blood · doi:10.1182/blood-2012-04-423525 · Cited by 556 · see citing works

Microvesicles derived from endothelial progenitor cells protect the kidney from ischemia–reperfusion injury by microRNA-dependent reprogramming of resident renal cells

Cantaluppi, V., Gatti, S., Medica, D., Figliolini, F., Bruno, S., Deregibus, M. C., Sordi, A., Biancone, L., Tetta, C., & Camussi, G. (2012) · Kidney International · doi:10.1038/ki.2012.105 · Cited by 535 · see citing works

Inflammation and its Resolution as Determinants of Acute Coronary Syndromes

Libby, P., Tabas, I. A., Fredman, G., & Fisher, E. A. A. (2014) · Circulation Research · doi:10.1161/circresaha.114.302699 · Cited by 523 · see citing works

Taber's Cyclopedic Medical Dictionary

(1963) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1963.tb27140.x · Cited by 447 · see citing works

RvE1 protects from local inflammation and osteoclastmediated bone destruction in periodontitis

Hastürk, H., Kantarcı, A., Ohira, T., Arita, M., Ebrahimi, N., Chiang, N., Petasis, N. A., Levy, B. D., Serhan, C. N., & Dyke, T. E. V. (2005) · The FASEB Journal · doi:10.1096/fj.05-4724fje · Cited by 437 · see citing works

Identification and signature profiles for pro-resolving and inflammatory lipid mediators in human tissue

Colas, R. A., Shinohara, M., Dalli, J., Chiang, N., & Serhan, C. N. (2014) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00024.2014 · Cited by 424 · see citing works

Novel Lipid Mediators and Resolution Mechanisms in Acute Inflammation

Serhan, C. N. (2010) · The American Journal of Pathology · doi:10.2353/ajpath.2010.100322 · Cited by 421 · see citing works

Resolvin D1 and Its Precursor Docosahexaenoic Acid Promote Resolution of Adipose Tissue Inflammation by Eliciting Macrophage Polarization toward an M2-Like Phenotype

Titos, E., Rius, B., González-Périz, A., López-Vicario, C., Morán-Salvador, E., Martínez-Clemente, M., Arroyo, V., & Clària, J. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1100225 · Cited by 412 · see citing works

Identification of resolvin D2 receptor mediating resolution of infections and organ protection

Chiang, N., Dalli, J., Colas, R. A., & Serhan, C. N. (2015) · The Journal of Experimental Medicine · doi:10.1084/jem.20150225 · Cited by 388 · see citing works

Cell death and tissue remodeling in planarian regeneration

Pellettieri, J., Fitzgerald, P., Watanabe, S., Mancuso, J., Green, D. R., & Alvarado, A. S. (2009) · Developmental Biology · doi:10.1016/j.ydbio.2009.09.015 · Cited by 338 · see citing works

Resolution phase lipid mediators of inflammation: agonists of resolution

Serhan, C. N., & Chiang, N. (2013) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2013.05.012 · Cited by 332 · see citing works

Effects of Low-Dose Aspirin on Acute Inflammatory Responses in Humans

Morris, T., Stables, M. J., Hobbs, A. J., de Souza, P., Colville‐Nash, P., Warner, T. D., Newson, J., Bellingan, G. J., & Gilroy, D. W. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0900477 · Cited by 322 · see citing works

Ligand-specific conformational change of the G-protein–coupled receptor ALX/FPR2 determines proresolving functional responses

Cooray, S. N., Gobbetti, T., Montero‐Melendez, T., McArthur, S., Thompson, D., Clark, A. J. L., Flower, R. J., & Perretti, M. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1308253110 · Cited by 301 · see citing works

The novel 13 <i>S</i> ,14 <i>S</i> ‐epoxy‐maresin is converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A ₄ hydrolase (LTA ₄ H), and shifts macrophage phenotype

Dalli, J., Zhu, M., Vlasenko, N. A., Deng, B., Haeggström, J. Z., Petasis, N. A., & Serhan, C. N. (2013) · The FASEB Journal · doi:10.1096/fj.13-227728 · Cited by 283 · see citing works

Resolvin D1 Receptor Stereoselectivity and Regulation of Inflammation and Proresolving MicroRNAs

Krishnamoorthy, S., Recchiuti, A., Chiang, N., Fredman, G., & Serhan, C. N. (2012) · The American Journal of Pathology · doi:10.1016/j.ajpath.2012.01.028 · Cited by 283 · see citing works

Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles

Dalli, J., Norling, L. V., Renshaw, D. W., Cooper, D., Leung, K., & Perretti, M. (2008) · Blood · doi:10.1182/blood-2008-02-140533 · Cited by 277 · see citing works

Resolvins D1, D2, and other mediators of self-limited resolution of inflammation in human blood following n-3 fatty acid supplementation

Mas, E., Croft, K. D., Zahra, P., Barden, A., & Mori, T. A. (2012) · Clinical Chemistry · doi:10.1373/clinchem.2012.190199 · Cited by 270 · see citing works

Omega-3 Fatty Acid-Derived Mediators 17( R )-Hydroxy Docosahexaenoic Acid, Aspirin-Triggered Resolvin D1 and Resolvin D2 Prevent Experimental Colitis in Mice

Bento, A. F., Claudino, R. F., Dutra, R. C., Marcon, R., & Calixto, J. Β. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1101305 · Cited by 258 · see citing works

Resolvin D1 Limits Polymorphonuclear Leukocyte Recruitment to Inflammatory Loci

Norling, L. V., Dalli, J., Flower, R. J., Serhan, C. N., & Perretti, M. (2012) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.112.249508 · Cited by 252 · see citing works

The interaction of human natural killer cells with either unpolarized or polarized macrophages results in different functional outcomes

Bellora, F., Castriconi, R., Dondero, A., Reggiardo, G., Moretta, L., Mantovani, A., Moretta, A., & Bottino, C. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1007654108 · Cited by 246 · see citing works

Rapid Appearance of Resolvin Precursors in Inflammatory Exudates: Novel Mechanisms in Resolution

Kasuga, K., Yang, R., Porter, T. F., Agrawal, N., Petasis, N. A., Irimia, D., Toner, M., & Serhan, C. N. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.12.8677 · Cited by 240 · see citing works

Lipopolysaccharide Signaling without a Nucleus: Kinase Cascades Stimulate Platelet Shedding of Proinflammatory IL-1β–Rich Microparticles

Brown, G. T., & McIntyre, T. M. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1001623 · Cited by 223 · see citing works

Cutting Edge: Humanized Nano-Proresolving Medicines Mimic Inflammation-Resolution and Enhance Wound Healing

Norling, L. V., Spite, M. R., Yang, R., Flower, R. J., Perretti, M., & Serhan, C. N. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1003865 · Cited by 206 · see citing works

The resolution of inflammation: the devil in the flask and in the details

Serhan, C. N. (2011) · The FASEB Journal · doi:10.1096/fj.11-0502ufm · Cited by 195 · see citing works

Resolution of inflammation

Willoughby, D. A., Moore, A., Colville‐Nash, P., & Gilroy, D. W. (2000) · International Journal of Immunopharmacology · doi:10.1016/s0192-0561(00)00064-3 · Cited by 190 · see citing works

Maresin Biosynthesis and Identification of Maresin 2, a New Anti-Inflammatory and Pro-Resolving Mediator from Human Macrophages

Deng, B., Wang, C., Arnardottir, H. H., Li, Y., Cheng, C.-Y. C., Dalli, J., & Serhan, C. N. (2014) · PLoS ONE · doi:10.1371/journal.pone.0102362 · Cited by 188 · see citing works

Transgenic restoration of long-chain n-3 fatty acids in insulin target tissues improves resolution capacity and alleviates obesity-linked inflammation and insulin resistance in high-fat-fed mice

White, P. J., Arita, M., Taguchi, R., Kang, J. X., & Marette, A. (2010) · Diabetes · doi:10.2337/db10-0054 · Cited by 185 · see citing works

Resolution of Inflammation in Murine Autoimmune Arthritis Is Disrupted by Cyclooxygenase-2 Inhibition and Restored by Prostaglandin E2-Mediated Lipoxin A4 Production

Chan, M. M.-Y., & Moore, A. R. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0903816 · Cited by 183 · see citing works

Human ALX receptor regulates neutrophil recruitment in transgenic mice: roles in inflammation and host defense

Devchand, P. R., Arita, M., Hong, S., Bannenberg, G. L., Moussignac, R., Gronert, K., & Serhan, C. N. (2003) · The FASEB Journal · doi:10.1096/fj.02-0770com · Cited by 176 · see citing works

Vagus nerve controls resolution and pro-resolving mediators of inflammation

Mirakaj, V., Dalli, J., Granja, T., Rosenberger, P., & Serhan, C. N. (2014) · Journal of Experimental Medicine · doi:10.1084/jem.20132103 · Cited by 176 · see citing works

Aging Delays Resolution of Acute Inflammation in Mice: Reprogramming the Host Response with Novel Nano-Proresolving Medicines

Arnardottir, H. H., Dalli, J., Colas, R. A., Shinohara, M., & Serhan, C. N. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1401313 · Cited by 171 · see citing works

Metabolic Inactivation of Resolvin E1 and Stabilization of Its Anti-inflammatory Actions

Arita, M., Oh, S. F., Chonan, T., Hong, S., Elangovan, S., Sun, Y., Uddin, J., Petasis, N. A., & Serhan, C. N. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m603766200 · Cited by 168 · see citing works

Sonic hedgehog carried by microparticles corrects endothelial injury through nitric oxide release

AgouTii, A., Mostefai, H. A., Porro, C., Carusio, N., Favre, J., Richard, V. J., Henrion, D., Martínez, M. C., & Andriantsitohaina, R. (2007) · The FASEB Journal · doi:10.1096/fj.07-8079com · Cited by 168 · see citing works

Human inflammatory and resolving lipid mediator responses to resistance exercise and ibuprofen treatment

Markworth, J. F., Vella, L. D., Lingard, B. S., Tull, D., Rupasinghe, T., Sinclair, A. J., Maddipati, K. R., & Cameron‐Smith, D. (2013) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00128.2013 · Cited by 163 · see citing works

Role of Basic Science in the Development of New Medicines: Examples from the Eicosanoid Field

Samuelsson, B. O. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.x112.351437 · Cited by 157 · see citing works

Exploiting the Annexin A1 pathway for the development of novel anti‐inflammatory therapeutics

Perretti, M., & Dalli, J. (2009) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2009.00483.x · Cited by 155 · see citing works

17(R)‐resolvin D1 specifically inhibits transient receptor potential ion channel vanilloid 3 leading to peripheral antinociception

Bang, S., Yoo, S., Yang, T., Cho, H., & Hwang, S. W. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01568.x · Cited by 148 · see citing works

Controlling Herpes Simplex Virus-Induced Ocular Inflammatory Lesions with the Lipid-Derived Mediator Resolvin E1

Rajasagi, N. K., Reddy, P. B. J., Suryawanshi, A. S., Mulik, S., Gjorstrup, P., & Rouse, B. T. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1003456 · Cited by 139 · see citing works

Human milk proresolving mediators stimulate resolution of acute inflammation

Arnardottir, H. H., Orr, S. K., Dalli, J., & Serhan, C. N. (2015) · Mucosal Immunology · doi:10.1038/mi.2015.99 · Cited by 131 · see citing works

Metchnikoff and the Origins of Immunology

Tauber, A. I., & Chernyak, L. (1991) · doi:10.1093/oso/9780195064476.001.0001 · Cited by 129 · see citing works

Resolvin E1 and Chemokine-like Receptor 1 Mediate Bone Preservation

Gao, L., Faibish, D., Fredman, G., Herrera, B. S., Chiang, N., Serhan, C. N., Dyke, T. E. V., & Gyurko, R. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1103688 · Cited by 127 · see citing works

High levels of anti-inflammatory and pro-resolving lipid mediators lipoxins and resolvins and declining docosahexaenoic acid levels in human milk during the first month of lactation

Weiss, G. A., Troxler, H., Klinke, G., Rogler, D., Braegger, C., & Hersberger, M. (2013) · Lipids in Health and Disease · doi:10.1186/1476-511x-12-89 · Cited by 120 · see citing works

Inhaled Carbon Monoxide Accelerates Resolution of Inflammation via Unique Proresolving Mediator–Heme Oxygenase-1 Circuits

Chiang, N., Shinohara, M., Dalli, J., Mirakaj, V., Kibi, M., Choi, A. M. K., & Serhan, C. N. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1202969 · Cited by 117 · see citing works

Metchnikoff and the origins of immunology: from metaphor to theory

(1992) · Choice Reviews Online · doi:10.5860/choice.29-5110 · Cited by 116 · see citing works

Dichotomy in duration and severity of acute inflammatory responses in humans arising from differentially expressed proresolution pathways

Morris, T., Stables, M. J., Colville‐Nash, P., Newson, J., Bellingan, G. J., de Souza, P. M., & Gilroy, D. W. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1000373107 · Cited by 106 · see citing works

Metabolomics‐Lipidomics of Eicosanoids and Docosanoids Generated by Phagocytes

Yang, R., Chiang, N., Oh, S. F., & Serhan, C. N. (2011) · Current Protocols in Immunology · doi:10.1002/0471142735.im1426s95 · Cited by 104 · see citing works

Effects of maternal n-3 fatty acid supplementation on placental cytokines, pro-resolving lipid mediators and their precursors

Keelan, J. A., Mas, E., D’Vaz, N., Dunstan, J. A., Li, S., Barden, A. E., Mark, P. J., Waddell, B. J., Prescott, S. L., & Mori, T. A. (2014) · Reproduction · doi:10.1530/rep-14-0549 · Cited by 100 · see citing works

Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis

Flannigan, K. L., Agbor, T. A., Blackler, R. W., Kim, J., Khan, W. I., Verdu, E. F., Ferraz, J. G., & Wallace, J. L. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1413390111 · Cited by 97 · see citing works

Microparticle alpha‐2‐macroglobulin enhances pro‐resolving responses and promotes survival in sepsis

Dalli, J., Norling, L. V., Montero‐Melendez, T., Canova, D. F., Lashin, H., Pavlov, A. M., Sukhorukov, G. B., Hinds, C., & Perretti, M. (2013) · EMBO Molecular Medicine · doi:10.1002/emmm.201303503 · Cited by 95 · see citing works

A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation

Brancaleone, V., Gobbetti, T., Cénac, N., Faouder, P. L., Colom, B., Flower, R. J., Vergnolle, N., Nourshargh, S., & Perretti, M. (2013) · Blood · doi:10.1182/blood-2013-04-496661 · Cited by 94 · see citing works

Short-term n-3 fatty acid supplementation but not aspirin increases plasma proresolving mediators of inflammation

Barden, A. E., Mas, E., Croft, K. D., Phillips, M. R., & Mori, T. A. (2014) · Journal of Lipid Research · doi:10.1194/jlr.m045583 · Cited by 86 · see citing works

Resolvin D1 and aspirin-triggered resolvin D1 regulate histamine-stimulated conjunctival goblet cell secretion

Li, D., Hodges, R. R., Jiao, J., Carozza, R. B., Shatos, M. A., Chiang, N., Serhan, C. N., & Dartt, D. A. (2013) · Mucosal Immunology · doi:10.1038/mi.2013.7 · Cited by 82 · see citing works

A randomized controlled trial of the effects of n-3 fatty acids on resolvins in chronic kidney disease

Mas, E., Barden, A. E., Burke, V., Beilin, L. J., Watts, G. F., Huang, R., Puddey, I. B., Irish, A. B., & Mori, T. A. (2015) · Clinical Nutrition · doi:10.1016/j.clnu.2015.04.004 · Cited by 73 · see citing works

Mediator-lipidomics: databases and search algorithms for PUFA-derived mediators

Lu, Y., Hong, S., Tjonahen, E., & Serhan, C. N. (2005) · Journal of Lipid Research · doi:10.1194/jlr.d400020-jlr200 · Cited by 71 · see citing works

Maternal dietary omega-3 fatty acid intake increases resolvin and protectin levels in the rat placenta

Jones, M. L., Mark, P. J., Keelan, J. A., Barden, A. E., Mas, E., Mori, T. A., & Waddell, B. J. (2013) · Journal of Lipid Research · doi:10.1194/jlr.m039842 · Cited by 64 · see citing works

Determination of ω-6 and ω-3 PUFA metabolites in human urine samples using UPLC/MS/MS

Sasaki, A., Fukuda, H., Shiida, N., Tanaka, N. K., Furugen, A., Ogura, J., Shuto, S., Mano, N., & Yamaguchi, H. (2015) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-014-8412-5 · Cited by 58 · see citing works

Tonic inhibition of chemotaxis in human plasma

Malawista, S. E., Chevance, A. D. B., Damme, J. V., & Serhan, C. N. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0802572105 · Cited by 54 · see citing works

Baking Reduces Prostaglandin, Resolvin, and Hydroxy-Fatty Acid Content of Farm-Raised Atlantic Salmon ( Salmo salar )

Raatz, S. K., Golovko, M. Y., Brose, S. A., Rosenberger, T. A., Burr, G., Wolters, W. R., & Picklo, M. J. (2011) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf202576k · Cited by 42 · see citing works

Microparticles are novel effectors of immunity

Norling, L. V., & Dalli, J. (2013) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2013.05.008 · Cited by 39 · see citing works

Pro-resolving lipids offer a helping hand to antibiotics

Legg, K. (2012) · Nature Reviews Drug Discovery · doi:10.1038/nrd3760 · Cited by 2 · see citing works

Human Milk Stimulates Resolution of Acute Inflammation

Arnardottir, H. H., Orr, S. K., Dalli, J., & Serhan, C. N. (2015) · The FASEB Journal · doi:10.1096/fasebj.29.1_supplement.913.14 · Cited by 1 · see citing works

Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities

Bäck, M., Yurdagul, A., Tabas, I., Öörni, K., & Kovanen, P. T. (2019) · Nature Reviews Cardiology · doi:10.1038/s41569-019-0169-2 · Cited by 1,341 · see citing works

Efferocytosis in health and disease

Doran, A. C., Yurdagul, A., & Tabas, I. (2020) · Nature Reviews Immunology · doi:10.1038/s41577-019-0240-6 · Cited by 1,066 · see citing works

Skin Acute Wound Healing: A Comprehensive Review

Cañedo‐Dorantes, L., & Cañedo-Ayala, M. (2019) · International Journal of Inflammation · doi:10.1155/2019/3706315 · Cited by 712 · see citing works

Technical challenges of working with extracellular vesicles

Ramirez, M. I., de Amorim, M. G., Gadelha, C., Milic, I., Welsh, J. A., Freitas, V. M., Nawaz, M., Akbar, N., Couch, Y., Makin, L., et al. (2017) · Nanoscale · doi:10.1039/c7nr08360b · Cited by 518 · see citing works

Macrophages: The Good, the Bad, and the Gluttony

Ross, E. A., Devitt, A., & Johnson, J. R. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.708186 · Cited by 436 · see citing works

Innate immune cell-epithelial crosstalk during wound repair.

Brazil, J., Quirós, M., Nusrat, A., & Parkos, C. (2019) · Journal of Clinical Investigation · doi:10.1172/jci124618 · Cited by 225 · see citing works

Arachidonic acid and other unsaturated fatty acids and some of their metabolites function as endogenous antimicrobial molecules: A review

Das, U. N. (2018) · Journal of Advanced Research · doi:10.1016/j.jare.2018.01.001 · Cited by 256 · see citing works

The role of efferocytosis‐fueled macrophage metabolism in the resolution of inflammation

Schilperoort, M., Ngai, D., Sukka, S. R., Avrampou, K., Shi, H., & Tabas, I. A. (2023) · Immunological Reviews · doi:10.1111/imr.13214 · Cited by 181 · see citing works

Macrophages, Wound Healing, and Fibrosis: Recent Insights

Smigiel, K. S., & Parks, W. (2018) · Current Rheumatology Reports · doi:10.1007/s11926-018-0725-5 · Cited by 158 · see citing works

Macrophages and skeletal health

Michalski, M. N., & McCauley, L. K. (2017) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2017.02.017 · Cited by 172 · see citing works

Keep calm: the intestinal barrier at the interface of peace and war

Thoo, L., Noti, M., & Krebs, P. (2019) · Cell Death and Disease · doi:10.1038/s41419-019-2086-z · Cited by 162 · see citing works

High-Risk Atherosclerosis and Metabolic Phenotype: The Roles of Ectopic Adiposity, Atherogenic Dyslipidemia, and Inflammation

Lechner, K., McKenzie, A. L., Kränkel, N., von Schacky, C., Worm, N., Nixdorff, U., Lechner, B., Scherr, J., Weingärtner, O., & Krauss, R. M. (2020) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2019.0115 · Cited by 141 · see citing works

Polyphenols in health and food processing: antibacterial, anti-inflammatory, and antioxidant insights

Sun, S., Liu, Z., Lin, M., Gao, N., & Wang, X. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1456730 · Cited by 125 · see citing works

Regulation of Inflammatory Reaction in Health and Disease

Fioranelli, M., Roccia, M. G., Flavin, D., & Cota, L. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22105277 · Cited by 122 · see citing works

Pathogenic stromal cells as therapeutic targets in joint inflammation

Dakin, S. G., Coles, M. C., Sherlock, J. P., Powrie, F. M., Carr, A. J., & Buckley, C. D. (2018) · Nature Reviews Rheumatology · doi:10.1038/s41584-018-0112-7 · Cited by 107 · see citing works

Staphylococcus aureus-Derived α-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution

Jordan, P. M., Gerstmeier, J., Pace, S., Bilancia, R., Rao, Z., Börner, F., Miek, L., Gutiérrez‐Gutiérrez, Ó., Arakandy, V., Rossi, A., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.108247 · Cited by 93 · see citing works

What Exactly Is Inflammation (and What Is It Not?)

Oronsky, B. T., Caroen, S. Z., & Reid, T. R. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232314905 · Cited by 92 · see citing works

Towards a personalised approach in exercise-based cardiovascular rehabilitation: How can translational research help? A ‘call to action’ from the Section on Secondary Prevention and Cardiac Rehabilitation of the European Association of Preventive Cardiology

Gevaert, A. B., Adams, V., Bahls, M., Bowen, T. S., Cornelissen, V., Dörr, M., Hansen, D., Kemps, H., Leeson, P., Craenenbroeck, E. M. V., et al. (2019) · European Journal of Preventive Cardiology · doi:10.1177/2047487319877716 · Cited by 82 · see citing works

The role of the host—Neutrophil biology

Chapple, I. L. C., Hirschfeld, J., Kantarci, A., Wilensky, A., & Shapira, L. (2023) · Periodontology 2000 · doi:10.1111/prd.12490 · Cited by 83 · see citing works

Inflammatory arthritis disrupts gut resolution mechanisms, promoting barrier breakdown by Porphyromonas gingivalis

Flak, M. B., Colas, R. A., Muñoz-Atienza, E., Curtis, M. A., Dalli, J., & Pitzalis, C. (2019) · JCI Insight · doi:10.1172/jci.insight.125191 · Cited by 72 · see citing works

Specialized pro‐resolving mediators: biosynthesis and biological role in bacterial infections

Jordan, P. M., & Werz, O. (2021) · FEBS Journal · doi:10.1111/febs.16266 · Cited by 69 · see citing works

Specialized Pro-Resolving Mediators Mitigate Cancer-Related Inflammation: Role of Tumor-Associated Macrophages and Therapeutic Opportunities

Lavy, M., Gauttier, V., Poirier, N., Barillé‐Nion, S., & Blanquart, C. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.702785 · Cited by 65 · see citing works

Use of DAMPs and SAMPs as Therapeutic Targets or Therapeutics: A Note of Caution

Land, W. G. (2020) · Molecular Diagnosis & Therapy · doi:10.1007/s40291-020-00460-z · Cited by 65 · see citing works

PDn-3 DPA Pathway Regulates Human Monocyte Differentiation and Macrophage Function

Pistorius, K., Souza, P. R., Matteis, R. D., Austin‐Williams, S., Primdahl, K. G., Vik, A., Mazzacuva, F., Colas, R. A., Marques, R. M., Hansen, T. V., et al. (2018) · Cell chemical biology · doi:10.1016/j.chembiol.2018.04.017 · Cited by 60 · see citing works

Evidence-Based Strategies for the Prehabilitation of the Abdominal Wall Reconstruction Patient

Joslyn, N. A., Esmonde, N. O., Martindale, R. G., Hansen, J., Khansa, I., & Janis, J. E. (2018) · Plastic & Reconstructive Surgery · doi:10.1097/prs.0000000000004835 · Cited by 58 · see citing works

Contribution of Wound-Associated Cells and Mediators in Orchestrating Gastrointestinal Mucosal Wound Repair

Quirós, M., & Nusrat, A. (2018) · Annual Review of Physiology · doi:10.1146/annurev-physiol-020518-114504 · Cited by 47 · see citing works

The Role of Maresins in Inflammatory Pain: Function of Macrophages in Wound Regeneration

Hwang, S.-M., Chung, G., Kim, Y. H., & Park, C. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20235849 · Cited by 56 · see citing works

Maresin-1 suppresses IL-1β-induced MMP-13 secretion by activating the PI3K/AKT pathway and inhibiting the NF-κB pathway in synovioblasts of an osteoarthritis rat model with treadmill exercise

Lu, J., Feng, X., Zhang, H., Wei, Y., Yang, Y., Tian, Y., & Bai, L. (2020) · Connective Tissue Research · doi:10.1080/03008207.2020.1780218 · Cited by 53 · see citing works

Angiotensin-(1-7) Promotes Resolution of Neutrophilic Inflammation in a Model of Antigen-Induced Arthritis in Mice

Barroso, L. C., Magalhães, G. S., Galvão, I., Reis, A. C., Souza, D. G., Sousa, L. P., Santos, R. A. S., Campagnole‐Santos, M. J., Pinho, V., & Teixeira, M. M. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01596 · Cited by 53 · see citing works

Maresin 1 alleviates the inflammatory response, reduces oxidative stress and protects against cardiac injury in LPS-induced mice

Li, D., Wang, M., Ye, J., Zhang, J., Xu, Y. Q., Wang, Z., Zhao, M., Ye, D., & Wan, J. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.119467 · Cited by 52 · see citing works

Resolution therapy: Harnessing efferocytic macrophages to trigger the resolution of inflammation

Saas, P., Vetter, M., Maraux, M., Bonnefoy, F., & Perruche, S. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1021413 · Cited by 52 · see citing works

Dexmedetomidine restores septic renal function via promoting inflammation resolution in a rat sepsis model

Qiu, R., Yao, W., Ji, H., Yuan, D., Gao, X., Sha, W., Wang, F., Huang, P., & Hei, Z. (2018) · Life Sciences · doi:10.1016/j.lfs.2018.05.001 · Cited by 50 · see citing works

M2 macrophage polarization: a potential target in pain relief

Zhao, W., Ma, L., Deng, D., Zhang, T., Han, L., Xu, F., Huang, S., Ding, Y., & Chen, X. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1243149 · Cited by 49 · see citing works

Specialized Pro-Resolving Lipid Mediators: The Future of Chronic Pain Therapy?

Chávez-Castillo, M., Ortega, Á., Cudris–Torres, L., Durán, P., Rojas, M., Manzano, A., Garrido, B., Salazar, J. J., Silva, A., Rojas-Gómez, D. M., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms221910370 · Cited by 48 · see citing works

Cannabidiol acts as molecular switch in innate immune cells to promote the biosynthesis of inflammation-resolving lipid mediators

Peltner, L. K., Gluthmann, L., Börner, F. R., Pace, S., Hoffstetter, R. K., Kretzer, C., Bilancia, R., Pollastro, F., Koeberle, A., Appendino, G., et al. (2023) · Cell Chemical Biology · doi:10.1016/j.chembiol.2023.08.001 · Cited by 43 · see citing works

Soluble epoxide hydrolase inhibition enhances production of specialized pro‐resolving lipid mediator and promotes macrophage plasticity

Abdalla, H. B., Álvarez, C., Wu, Y., Rojas, P., Hammock, B. D., Maddipati, K. R., Trindade‐da‐Silva, C. A., Soares, M. Q. S., Clemente‐Napimoga, J. T., Kantarcı, A., et al. (2022) · British Journal of Pharmacology · doi:10.1111/bph.16009 · Cited by 42 · see citing works

Human macrophage polarization determines bacterial persistence of Staphylococcus aureus in a liver-on-chip-based infection model

Siwczak, F., Cseresnyés, Z., Hassan, M. I. A., Aina, K. O., Carlstedt, S., Sigmund, A., Gröger, M., Surewaard, B. G. J., Werz, O., Figge, M. T., et al. (2022) · Biomaterials · doi:10.1016/j.biomaterials.2022.121632 · Cited by 42 · see citing works

Glucocorticoids regulate lipid mediator networks by reciprocal modulation of 15-lipoxygenase isoforms affecting inflammation resolution

Rao, Z., Brunner, E., Giszas, B., Iyer-Bierhoff, A., Gerstmeier, J., Börner, F., Jordan, P. M., Pace, S., Meyer, K. P. L., Hofstetter, R. K., et al. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2302070120 · Cited by 42 · see citing works

Saving Problematic Mucosae: SPMs in Intestinal Mucosal Inflammation and Repair

Quirós, M., & Nusrat, A. (2019) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2018.12.004 · Cited by 41 · see citing works

Low levels of pro-resolving lipid mediators lipoxin-A4, resolvin-D1 and resolvin-E1 in patients with rheumatoid arthritis

Özdemir, R. B. Ö., Gündüz, Ö. S., Özdemir, A. T., & Akgül, Ö. (2020) · Immunology Letters · doi:10.1016/j.imlet.2020.08.006 · Cited by 40 · see citing works

The Neuroimmune Interplay in Joint Pain: The Role of Macrophages

Vasconcelos, D. P., Jabangwe, C., Lamghari, M., & Alves, C. J. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.812962 · Cited by 41 · see citing works

Unified nexus of macrophages and maresins in cardiac reparative mechanisms

Jadapalli, J. K., & Halade, G. V. (2018) · The FASEB Journal · doi:10.1096/fj.201800254r · Cited by 38 · see citing works

Inhibition of neogenin fosters resolution of inflammation and tissue regeneration

Schlegel, M., Körner, A., Kaussen, T., Knausberg, U., Gerber, C., Hansmann, G., Jónasdóttir, H. S., Giera, M. A., & Mirakaj, V. (2018) · Journal of Clinical Investigation · doi:10.1172/jci96259 · Cited by 37 · see citing works

Immune responsive resolvin D1 programs peritoneal macrophages and cardiac fibroblast phenotypes in diversified metabolic microenvironment

Kain, V., & Halade, G. V. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27165 · Cited by 37 · see citing works

Mesenchymal Stromal Cell Therapy in Solid Organ Transplantation

Podestà, M. A., Remuzzi, G., & Casiraghi, F. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2020.618243 · Cited by 34 · see citing works

Innate Immune Training Initiates Efferocytosis to Protect against Lung Injury

Kang, Y., Kim, D., Lee, S., Kim, H., Kim, T.-B., Cho, J. A., Lee, T., & Choi, E. Y. (2024) · Advanced Science · doi:10.1002/advs.202308978 · Cited by 31 · see citing works

Emergence of Mixed‐Oil Fat Emulsions for Use in Parenteral Nutrition

Mundi, M. S., Martindale, R. G., & Hurt, R. T. (2017) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607117742595 · Cited by 32 · see citing works

Efferocytosis: Unveiling its potential in autoimmune disease and treatment strategies

Xing, J., Wang, K., Xu, Y.-C., Pei, Z.-J., Yu, Q., Liu, X., Dong, Y.-L., Li, S., Chen, Y., Zhao, Y., et al. (2024) · Autoimmunity Reviews · doi:10.1016/j.autrev.2024.103578 · Cited by 31 · see citing works

Vacuolar (H+)-ATPase Critically Regulates Specialized Proresolving Mediator Pathways in Human M2-like Monocyte-Derived Macrophages and Has a Crucial Role in Resolution of Inflammation

Rao, Z., Pace, S., Jordan, P. M., Bilancia, R., Troisi, F., Börner, F., Andreas, N., Kamradt, T., Menche, D., Rossi, A., et al. (2019) · The Journal of Immunology · doi:10.4049/jimmunol.1900236 · Cited by 31 · see citing works

The function of specialized pro-resolving endogenous lipid mediators, vitamins, and other micronutrients in the control of the inflammatory processes: Possible role in patients with SARS-CoV-2 related infection

Gallo, C. G., Fiorino, S., Posabella, G., Antonacci, D., Tropeano, A., Pausini, E., Pausini, C., Guarniero, T., Hong, W., Giampieri, E., et al. (2022) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2022.106619 · Cited by 32 · see citing works

microRNA-181b is increased in cystic fibrosis cells and impairs lipoxin A4 receptor-dependent mechanisms of inflammation resolution and antimicrobial defense

Pierdomenico, A. M., Patruno, S., Codagnone, M., Simiele, F., Mari, V. C., Plebani, R., Recchiuti, A., & Romano, M. (2017) · Scientific Reports · doi:10.1038/s41598-017-14055-y · Cited by 30 · see citing works

Neural and immune roles in osteoarthritis pain: Mechanisms and intervention strategies

Zou, Y., Liu, C., Wang, Z., Li, G., & Xiao, J. (2024) · Journal of Orthopaedic Translation · doi:10.1016/j.jot.2024.07.010 · Cited by 26 · see citing works

Maresin-1 induces cardiomyocyte hypertrophy through IGF-1 paracrine pathway

Wahyuni, T., Kobayashi, A., Tanaka, S., Miyake, Y., Yamamoto, A., Bahtiar, A., Mori, S., Kametani, Y., Tomimatsu, M., Matsumoto, K., et al. (2021) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00568.2020 · Cited by 26 · see citing works

The Natural Combination Medicine Traumeel (Tr14) Improves Resolution of Inflammation by Promoting the Biosynthesis of Specialized Pro-Resolving Mediators

Jordan, P. M., Goethem, E. V., Müller, A. M., Hemmer, K., Gavioli, V., Baillif, V., Burmeister, Y., Krömmelbein, N., Dubourdeau, M., Seilheimer, B., et al. (2021) · Pharmaceuticals · doi:10.3390/ph14111123 · Cited by 25 · see citing works

Novel mechanism of regulation of the 5-lipoxygenase/leukotriene B4 pathway by high-density lipoprotein in macrophages

Tsuda, S., Shinohara, M., Oshita, T., Nagao, M., Tanaka, N. K., Mori, T., Hara, T., Irino, Y., Toh, R., Ishida, T., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-13154-0 · Cited by 25 · see citing works

Lipoxin A4 activates ALX/FPR2 to attenuate inflammation in Aspergillus fumigatus keratitis

Zhu, X., Peng, X., Lin, J., Zhang, Y., He, H. Z., & Zhao, G. (2021) · International Immunopharmacology · doi:10.1016/j.intimp.2021.107785 · Cited by 22 · see citing works

Apoptotic cell-derived metabolites in efferocytosis-mediated resolution of inflammation

Mao, Y. (2021) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2021.10.002 · Cited by 21 · see citing works

Resident macrophages in the healthy and inflamed intestinal muscularis externa

Wehner, S., & Engel, D. R. (2017) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-017-1948-4 · Cited by 21 · see citing works

Matrix stiffness regulates bone repair by modulating 12-lipoxygenase-mediated early inflammation

Yao, D., Qiao, F., Song, C., & Lv, Y. (2021) · Materials Science and Engineering C · doi:10.1016/j.msec.2021.112359 · Cited by 21 · see citing works

Can Specialized Pro-resolving Mediators Deliver Benefit Originally Expected from Fish Oil?

Rosenthal, M. D., Patel, J. J., Staton, K. M., Martindale, R. G., Moore, F. A., & Upchurch, G. R. (2018) · Current Gastroenterology Reports · doi:10.1007/s11894-018-0647-4 · Cited by 20 · see citing works

Protective Potential of Maresins in Cardiovascular Diseases

Liu, M., He, H., & Chen, L. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.923413 · Cited by 19 · see citing works

Molecular Mechanisms for the Inflammation-Resolving Actions of Lenabasum

BURSTEIN, S. H. (2020) · Molecular Pharmacology · doi:10.1124/molpharm.120.000083 · Cited by 19 · see citing works

CF Patients’ Airway Epithelium and Sex Contribute to Biosynthesis Defects of Pro-Resolving Lipids

Shum, M., London, C., Briottet, M., Sy, K. A., Baillif, V., Philippe, R., Zare, A., Ghorbani-Dalini, S., Remus, N., Tarze, A., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.915261 · Cited by 19 · see citing works

Metabolic reprogramming in efferocytosis

Yan, Q., Li, K., Chen, L., Wang, A., Xi, Y., Xiao, H., & Yuan, L. (2025) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2025.1677028 · Cited by 18 · see citing works

Staphylococcus aureus controls eicosanoid and specialized pro‐resolving mediator production via lipoteichoic acid

Miek, L., Jordan, P. M., Günther, K., Pace, S., Beyer, T., Kowalak, D., Hoerr, V., Löffler, B., Tuchscherr, L. P. N., Serhan, C. N., et al. (2022) · Immunology · doi:10.1111/imm.13449 · Cited by 18 · see citing works

The role of transient receptor potential (TRP) channels in phagocytosis: A comprehensive review

Alavi, M. S., Soheili, V., & Roohbakhsh, A. (2023) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2023.176302 · Cited by 17 · see citing works

Pro-resolving lipid mediators in diseases: exploring the molecular basis and clinical implication

Li, C., Wang, Z., Yang, Y., Jiang, Q., Jiang, Y., Xiao, J., Shen, L., Wu, W., & Li, C. (2026) · Molecular Biomedicine · doi:10.1186/s43556-025-00400-5 · Cited by 19 · see citing works

Maresin 1, a specialized proresolving mediator, stimulates intracellular [Ca2+] and secretion in conjunctival goblet cells

Olsen, M. V., Lyngstadaas, A. V., Bair, J. A., Hodges, R. R., Utheim, T. P., Serhan, C. N., & Dartt, D. A. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.29846 · Cited by 16 · see citing works

General Features of Autoimmune Disease

Davidson, A., & Diamond, B. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-812102-3.00003-8 · Cited by 16 · see citing works

The roles of migrasomes in immunity, barriers, and diseases

Cai, C., & Shen, J. (2024) · Acta Biomaterialia · doi:10.1016/j.actbio.2024.09.013 · Cited by 15 · see citing works

Macrophage Long Non-Coding RNAs in Pathogenesis of Cardiovascular Disease

Wysoczynski, M., Kim, J. I., Moore, J. B., & Uchida, S. (2020) · Non-Coding RNA · doi:10.3390/ncrna6030028 · Cited by 14 · see citing works

Efferocytosis in tissue engineering: A comprehensive review of emerging therapeutic strategies for enhanced tissue repair and regeneration

Zhang, Y., Nie, R., Feng, Z.-Y., Fan, M., Shen, Z., Zhang, X., Zhang, Q., Zou, C., Zhang, J., Huang, K., et al. (2025) · Bioactive Materials · doi:10.1016/j.bioactmat.2025.05.026 · Cited by 13 · see citing works

Specialized Pro-Resolving Lipid Mediators and Dietary Omega-3/6 Fatty Acids in Selected Inflammatory Skin Diseases: A Systematic Review

Bielach-Bazyluk, A., Jakubowicz-Zalewska, O., Myśliwiec, H., & Flisiak, I. (2025) · Antioxidants · doi:10.3390/antiox15010009 · Cited by 13 · see citing works

The mechanism of efferocytosis in the pathogenesis of periodontitis and its possible therapeutic strategies

Huang, Z., Zhao, Q., Jiang, X., & Li, Z. (2023) · Journal of Leukocyte Biology · doi:10.1093/jleuko/qiad016 · Cited by 13 · see citing works

Dietary Technologies to Optimize Healing from Injury-Induced Inflammation

Sears, B., Perry, M., & Saha, A. K. (2020) · Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry · doi:10.2174/1871523019666200512114210 · Cited by 12 · see citing works

Low LXA4, RvD1 and RvE1 levels may be an indicator of the development of hypertension

Yücel, H., & Özdemir, A. T. (2021) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2021.102365 · Cited by 12 · see citing works

Oxygenated lipid signaling in tumor-associated macrophages—focus on colon cancer

Colby, J. K., Jaoude, J. C., Liu, F., & Shureiqi, I. (2018) · Cancer and Metastasis Reviews · doi:10.1007/s10555-018-9743-z · Cited by 12 · see citing works

Novel n-3 Docosapentaneoic Acid-Derived Pro-resolving Mediators Are Vasculoprotective and Mediate the Actions of Statins in Controlling Inflammation

Dalli, J., Pistorius, K., & Walker, M. E. (2019) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-21735-8_7 · Cited by 12 · see citing works

Maresin 1 Exerts a Tissue-Specific Regulation of Adipo-Hepato-Myokines in Diet-Induced Obese Mice and Modulates Adipokine Expression in Cultured Human Adipocytes in Basal and Inflammatory Conditions

Martínez‐Fernández, L., Burgos, M., Sáinź, N., Laiglesia, L. M., Arbonés-Mainar, J. M., González‐Muniesa, P., & Moreno-Aliaga, M. J. (2023) · Biomolecules · doi:10.3390/biom13060919 · Cited by 11 · see citing works

Modulation of Inflammation-Related Lipid Mediator Pathways by Celastrol During Human Macrophage Polarization

Zhang, K., Jordan, P. M., Pace, S., Hofstetter, R. K., Werner, M., Chen, X., & Werz, O. (2022) · Journal of Inflammation Research · doi:10.2147/jir.s356964 · Cited by 10 · see citing works

Fatty acid-mediated signaling as a target for developing type 1 diabetes therapies

Ludovico, I. D., Sarkar, S., Elliott, E. C., Virtanen, S. M., Erlund, I., Ramanadham, S., Mirmira, R. G., Metz, T., & Nakayasu, E. S. (2023) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2023.2259099 · Cited by 11 · see citing works

Improving Functional Muscle Regeneration in Volumetric Muscle Loss Injuries by Shifting the Balance of Inflammatory and Pro-Resolving Lipid MediatorsPreprint

Turner, T., Pittman, F. S., Zhang, H., Hymel, L. A., Zheng, T., Behara, M., Anderson, S. E., Harrer, J. A., Link, K. A., Ahammed, M. A., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.09.06.611741 · Cited by 10 · see citing works

Macrophage polarization by potential nutraceutical compounds: A strategic approach to counteract inflammation in atherosclerosis

Sottero, B., Testa, G., Gamba, P., Staurenghi, E., Giannelli, S., & Leonarduzzi, G. (2022) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2022.02.010 · Cited by 9 · see citing works

D-mannose acts as a V-ATPase inhibitor to suppress inflammatory cytokines generation and bacterial killing in macrophage

Zhao, M., Chen, N., Guo, Y., Wu, N., Cao, B., Zhan, B., Li, Y., Zhou, T., Zhu, F., Guo, C. H., et al. (2023) · Molecular Immunology · doi:10.1016/j.molimm.2023.08.013 · Cited by 8 · see citing works

The Immune-Centric Revolution Translated into Clinical Application: Peripheral Blood Mononuclear Cell (PBMNC) Therapy in Diabetic Patients with No-Option Critical Limb-Threatening Ischemia (NO-CLTI)—Rationale and Meta-Analysis of Observational Studies

Rehak, L., Giurato, L., Monami, M., Meloni, M., Scatena, A., Panunzi, A., Manti, G. M., Caravaggi, C. M. F., & Uccioli, L. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13237230 · Cited by 10 · see citing works

The impact of the soluble epoxide hydrolase cascade on periodontal tissues

Abdalla, H. B., & Dyke, T. E. V. (2023) · Frontiers in Dental Medicine · doi:10.3389/fdmed.2023.1129371 · Cited by 7 · see citing works

A review of perioperative immune-modulating and metabolic-modulating nutrition strategies for bowel resection surgery.

Walsh, M., & Martindale, R. (2024) · JPEN - Journal of Parenteral and Enteral Nutrition · doi:10.1002/jpen.2634 · Cited by 6 · see citing works

B10 cells promote pro-resolving macrophage function through direct cell-cell contact and IL-10 secretion in Raw 264.7 cells

Memida, T., Abdolahinia, E. D., Cao, G., Ruiz, S., Huang, S., Shindo, S., Nakamura, S., Lin, J., Kawai, T., & Han, X. (2025) · International Immunology · doi:10.1093/intimm/dxaf012 · Cited by 6 · see citing works

Anti-inflammatory actions of aspirin-triggered resolvin D1 (AT-RvD1) in bronchial epithelial cells stimulated by cigarette smoke extract

de Oliveira, J. R., Pereira, A. B. M., de Souza, H. I., dos Santos, W. M., Farnesi-de-Assunção, T. S., Vito, F. B. D., Moraes‐Souza, H., da Silva, P. R., da Silva, M. V., Rodrigues, V., et al. (2024) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2024.106833 · Cited by 6 · see citing works

Plasminogen and plasmin induce specialized proresolving mediators and promote efferocytosis via 5-lipoxygenase

Perucci, L. O., Carneiro, F. S., Souza, J., Grossi, L. C., Souza, J. A. M., Zaidan, I., Cardoso, C., Lara, E. S., Félix, F. B., Baik, N., et al. (2025) · Journal of Thrombosis and Haemostasis · doi:10.1016/j.jtha.2025.03.018 · Cited by 5 · see citing works

Polyunsaturated Fatty Acid-Derived Lipid Mediators as Potential Biomarkers for Leprosy Among Individuals with Asymptomatic Mycobacterium leprae Infection

Silva, C. A. M., Graham, B. G., Webb, K. J., Islam, M. N., Harton, M. R., Marques, M. A. M., de Carvalho, F. M., Pinheiro, R. O., Spencer, J. S., Sarno, E. N., et al. (2023) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.2c00585 · Cited by 5 · see citing works

Maresin1 is a predictive marker of new digital ulcers in systemic sclerosis patients

Pellicano, C., Romaggioli, L., Miglionico, M., Colalillo, A., Ramaccini, C., Gigante, A., Muscaritoli, M., & Rosato, E. (2022) · Microvascular Research · doi:10.1016/j.mvr.2022.104366 · Cited by 5 · see citing works

Macrophages in endometriosis

Panir, K., Hull, M. L., & Greaves, E. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-820661-4.00019-4 · Cited by 5 · see citing works

Contribution of plasma, placental, inflammatory and pro-resolving mediators in labor induction

Volpato, L. K., Nadkarni, S., Horewicz, V. V., Donatello, N. N., Parma, G. O. C., Martins, D. F., & Piovezan, A. P. (2022) · Placenta · doi:10.1016/j.placenta.2022.03.014 · Cited by 4 · see citing works

DAMP-Promoted Efferent Innate Immune Responses in Human Diseases: Inflammation

Land, W. G. (2020) · Springer eBooks · doi:10.1007/978-3-030-53868-2_5 · Cited by 4 · see citing works

Endogenous DAMPs, Category III: Inducible DAMPs (Cat. III DAMPs)

Land, W. G. (2018) · Springer eBooks · doi:10.1007/978-3-319-78655-1_14 · Cited by 3 · see citing works

Human CD24+CD38+ regulatory B cells promote pro-resolving macrophage function through the synergistic effect of IL-10 and PD-L1

Abdolahinia, E. D., Horta, E. M., Memida, T., Cao, G., Huang, S., Ruiz, S., Shindo, S., Nakamura, S., Lin, J., Vardar, S., et al. (2025) · Journal of Leukocyte Biology · doi:10.1093/jleuko/qiaf141 · Cited by 2 · see citing works

Efferocytosis: a therapeutic strategy for diabetes and its vascular complications

Song, Y., Yuan, J., Li, Y., Liu, Y., & Qin, G. (2025) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2025.1641748 · Cited by 2 · see citing works

Repercussions of microglial efferocytosis on neurodegeneration in Alzheimer’s Disease (AD): a double-edged sword and perplexing factor warranting scrutiny in AD research

Kanuri, S. H. (2024) · The Egyptian Journal of Neurology Psychiatry and Neurosurgery · doi:10.1186/s41983-024-00853-5 · Cited by 2 · see citing works

Lipids as regulators of inflammation and tissue regeneration

Tyurina, Y. Y., Tyurin, V. A., Kapralov, A. A., Hussey, G. S., Timashev, P. S., Shvedova, A. A., Badylak, S. F., & Kagan, V. E. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-821440-4.00005-0 · Cited by 1 · see citing works

Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators

Dalli, J., & Serhan, C. N. (2012) · Blood · doi:10.1182/blood-2012-04-423525 · Cited by 556 · see citing works

Pro‐Resolving Mediator Production by Human Phagocytes and their Transcellular Biosynthesis with Microparticles in Inflammation‐Resolution

Dalli, J., & Serhan, C. N. (2013) · The FASEB Journal · doi:10.1096/fasebj.27.1_supplement.1168.4

Pro-Resolving Mediators in Regulating and Conferring Macrophage Function

Dalli, J., & Serhan, C. N. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01400 · Cited by 147 · see citing works

Novel Lipid Mediators and Resolution Mechanisms in Acute Inflammation

Serhan, C. N. (2010) · The American Journal of Pathology · doi:10.2353/ajpath.2010.100322 · Cited by 421 · see citing works

Macrophages and the Entrance of Resolution Phase Lipid Mediators

Serhan, C. N., Chiang, N., & Dalli, J. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1311-4_13 · Cited by 3 · see citing works