Continuous non-invasive cardiac output measurements in the neonate by electrical velocimetry: A comparison with echocardiography
Abstract
OBJECTIVE: Electrical velocimetry (EV) is a non-invasive method of continuous left cardiac output monitoring based on measurement of thoracic electrical bioimpedance. The objective was to validate EV by investigating the agreement in cardiac output measurements performed by EV and echocardiography. DESIGN: In this prospective observational study, left ventricular output (LVO) was simultaneously measured by EV (LVO(ev)) using Aesculon and by echocardiography (LVO(echo)) in healthy term neonates during the first 2 postnatal days. To determine the agreement between the two methods, we calculated the bias (mean difference) and precision (1.96×SD of the difference). As LVO(echo) has its own limitations, the authors also calculated the 'true precision' of EV adjusted for echocardiography as the reference method. RESULTS: The authors performed 115 paired measurements in 20 neonates. LVO(ev) and LVO(echo) were similar (534±105 vs 538±105 ml/min, p=0.7). The bias and precision of EV were -4 and 234 ml/min, respectively. The authors found the true precision of EV to be similar to the precision of echocardiography (31.6% vs 30%, respectively). There was no difference in bias and precision between the measurements obtained in patients with or without a haemodynamically significant patent ductus arteriosus. CONCLUSIONS: EV is as accurate in measuring LVO as echocardiography and the variation in the agreement between EV and echocardiography among the individual subjects reflects the limitations of both techniques.
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Noori et al. examined left ventricular output in preterm neonates with and without patent ductus arteriosus, finding good agreement between the two modalities.
“while Noori et al. examined left ventricular output in preterm neonates with and without patent ductus arteriosus, finding good agreement between the two modalities [73].”
From Trends and Challenges in Noninvasive Hemodynamic Monitoring of Neonates Following Cardiac Surgery: A Narrative Review (2025) · cites this paper as [73]
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- Authors
- Noori, S., Drabu, B., Soleymani, S., & Seri, I.
- Affiliations
- University of Southern California (US)
- Children's Hospital of Oklahoma (US)
- 1Division of Neonatology and the Center for Fetal and Neonatal Medicine, Department of Pediatrics, Children's Hospital Los Angeles and the LAC+USC Medical Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
- Corresponding author
- Noori, Shahab
- ORCID
- Noori, Shahab
- Venue
- Archives of Disease in Childhood - Fetal and Neonatal Edition
- Publisher
- BMJ
- Published
- 2012-08-29
- Volume
- 97
- Issue
- 5
- Pages
- F340-F343
- ISSN
- 1359-2998 (ISSN-L)
- 1468-2052
- OpenAlex
- W2114998295
- Cited by
- 146
- References
- 16
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 10 · 2023: 8 · 2022: 8 · 2021: 14 · 2020: 12 · 2019: 15 · 2018: 13 · 2017: 13 · 2016: 17 · 2015: 11 · 2014: 9 · 2013: 1 · 2012: 5
- FWCI
- 8.43
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Disease in Childhood Fetal & Neonatal (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Hemodynamic Monitoring and Therapy
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Electrical and Bioimpedance Tomography
- Keywords
- electrical velocimetry, cardiac output monitoring, neonates, impedance cardiography, echocardiography, left ventricular output, measurement agreement, patent ductus arteriosus, noninvasive hemodynamic monitoring
- MeSH terms
- Cardiac Output, Echocardiography, Female, Humans, Infant, Newborn, Infant, Premature, Male, Monitoring, Physiologic, Prospective Studies, Rheology, Ventricular Function, Left, Critical Illness
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