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Cited by 347

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Depression and anxiety in people with inflammatory bowel disease

Open access
Kurina, L M, Goldacre, M J, Yeates, D, Gill, L E·2001·Journal of Epidemiology and Community Health
DOI 10.1136/jech.55.10.716
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Abstract

STUDY OBJECTIVE: To determine whether depression or anxiety co-occurs with ulcerative colitis (UC) or Crohn's disease (CD) more often than expected by chance, and, if so, whether the mental disorders generally precede or follow the inflammatory bowel diseases (IBD). DESIGN: Nested case-control studies using a database of linked hospital record abstracts. SETTING: Southern England. MAIN RESULTS: Both depression and anxiety preceded UC significantly more often than would be predicted from the control population's experience. The associations were strongest when the mental conditions were diagnosed shortly before UC, although the association between depression and UC was also significant when depression preceded UC by five or more years. Neither depression nor anxiety occurred before CD more often than expected by chance. However, depression and anxiety were significantly more common after CD; the associations were strongest in the year after the initial record of CD. UC was followed by anxiety, but not by depression, more often than expected by chance and, again, the association was strongest within one year of diagnosis with UC. CONCLUSIONS: The concentration of risk of depression or anxiety one year or less before diagnosis with UC suggests that the two psychiatric disorders might be a consequence of early symptoms of the as yet undiagnosed gastrointestinal condition. The data are also, however, compatible with the hypothesis that the psychiatric disorders could be aetiological factors in some patients with UC. Most of the excess anxiety or depression diagnosed subsequent to diagnosis of IBD occurs during the year after IBD is diagnosed and the probable explanation is that the mental disorders are sequelae of IBD.

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Metadata

Authors
Kurina, L. M., Goldacre, M. J., Yeates, D., & Gill, L. E.
Venue
Journal of Epidemiology and Community Health
Publisher
BMJ
Published
2001-10-01
Volume
55
Issue
10
Pages
716-720
ISSN
  • 0141-7681 (ISSN-L)
  • 0143-005X
  • 1470-2738
DOI
10.1136/jech.55.10.716
OpenAlex
W2153211583
Cited by
347
References
2
FWCI
1.73
Type
journal article
Language
en
Open access
bronze

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