Cited by 311Genomics and Phylogenetic StudiesChromosomal and Genetic VariationsGenetics, Bioinformatics, and Biomedical Research

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The Genome 10K Project: A Way Forward

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Koepfli, Klaus-Peter, Paten, Benedict, the Genome 10K Community of Scientists, O’Brien, Stephen J.·2015·Annual Review of Animal Biosciences

DOI 10.1146/annurev-animal-090414-014900PMC PMC5837290

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Abstract

The Genome 10K Project was established in 2009 by a consortium of biologists and genome scientists determined to facilitate the sequencing and analysis of the complete genomes of 10,000 vertebrate species. Since then the number of selected and initiated species has risen from ∼26 to 277 sequenced or ongoing with funding, an approximately tenfold increase in five years. Here we summarize the advances and commitments that have occurred by mid-2014 and outline the achievements and present challenges of reaching the 10,000-species goal. We summarize the status of known vertebrate genome projects, recommend standards for pronouncing a genome as sequenced or completed, and provide our present and future vision of the landscape of Genome 10K. The endeavor is ambitious, bold, expensive, and uncertain, but together the Genome 10K Consortium of Scientists and the worldwide genomics community are moving toward their goal of delivering to the coming generation the gift of genome empowerment for many vertebrate species.

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Authors: Koepfli, K.-P., Paten, B., Scientists, T. G. 1. C. O., & O’Brien, S. J.
Affiliations: St Petersburg University (RU)
New England Biolabs (United States) (US)
ORCID: Koepfli, Klaus-Peter
Paten, Benedict
Venue: Annual Review of Animal Biosciences
Publisher: Annual Reviews
Published: 2015-02-16
Volume: 3
Issue: 1
Pages: 57-111
ISSN: 2165-8102 (ISSN-L)
2165-8110
DOI: 10.1146/annurev-animal-090414-014900
PMC: PMC5837290
OpenAlex: W2152882637
Cited by: 311
References: 35
Citations by year: 2026: 9 · 2025: 11 · 2024: 16 · 2023: 15 · 2022: 30 · 2021: 41 · 2020: 36 · 2019: 32 · 2018: 43 · 2017: 33 · 2016: 34 · 2015: 11
FWCI: 3.96
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Annual Review of Animal Biosciences (publishedVersion)
PubMed (publishedVersion)
Research at the University of Copenhagen (University of Copenhagen) (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
RECERCAT (Consorci de Serveis Universitaris de Catalunya) (acceptedVersion)
NSUWorks (Nova Southeastern University) (submittedVersion)
University of Canberra Research Portal (submittedVersion)
eScholarship (California Digital Library) (submittedVersion)
Repositori digital de la UPF (Universitat Pompeu Fabra) (submittedVersion)
Funders: National Human Genome Research Institute (U54HG007990)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Chromosomal and Genetic Variations
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genetics, Bioinformatics, and Biomedical Research
Keywords: vertebrate genomes, genome sequencing, species selection
MeSH terms: Animals, Forecasting, Humans, Species Specificity, Vertebrates, Genome, Computational Biology, Genomics

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The Genome 10K Project: A Way Forward

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