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Whole food-based approaches to modulating gut microbiota and associated diseases
Abstract
Intake of whole foods, such as fruits and vegetables, may confer health benefits to the host. The beneficial effects of fruits and vegetables were mainly attributed to their richness in polyphenols and microbiota-accessible carbohydrates (MACs). Components in fruits and vegetables modulate composition and associated functions of the gut microbiota, whereas gut microbiota can transform components in fruits and vegetables to produce metabolites that are bioactive and important for health. The progression of multiple diseases, such as obesity and inflammatory bowel disease, is associated with diet and gut microbiota. Although the exact causality between these diseases and specific members of gut microbiota has not been well characterized, accumulating evidence supported the role of fruits and vegetables in modulating gut microbiota and decreasing the risks of microbiota-associated diseases. This review summarizes the latest findings on the effects of whole fruits and vegetables on gut microbiota and associated diseases.
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“A recent review has highlighted the benefits of whole fruit and vegetables, mostly attributed to their polyphenol and MAC content, on the microbiota and associated diseases, such as obesity and colonic inflammation (16).”
From Diet and the Microbiota–Gut–Brain Axis: Sowing the Seeds of Good Mental Health (2021) · cites this paper as [16]
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Metadata
- Authors
- Han, Y., & Xiao, H.
- Affiliations
- University of Massachusetts Amherst (US)
- Venue
- Annual Review of Food Science and Technology
- Publisher
- Annual Reviews
- Published
- 2020-03-25
- Volume
- 11
- Issue
- 1
- Pages
- 119-143
- ISSN
- 1941-1421 (ISSN-L)
- 1941-1413
- OpenAlex
- W2999951287
- Cited by
- 101
- References
- 143
- Citations by year
- 2026: 12 · 2025: 18 · 2024: 13 · 2023: 17 · 2022: 16 · 2021: 15 · 2020: 10
- FWCI
- 1.39
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annual Review of Food Science and Technology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Center for Complementary and Integrative Health (R01AT010229)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Keywords
- whole foods, gut microbiota, fruits, vegetables, polyphenols, gut microbiota metabolites, obesity, inflammatory bowel disease, diet and disease
- MeSH terms
- Gastrointestinal Microbiome, Diet, Food, Humans
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