Differential modulation of human intestinal Bifidobacterium populations after consumption of a wild blueberry (Vaccinium angustifolium) drink
Abstract
Bifidobacteria are gaining increasing interest as health-promoting bacteria. Nonetheless, the genus comprises several species, which can exert different effects on human host. Previous studies showed that wild blueberry drink consumption could selectively increase intestinal bifidobacteria, suggesting an important role for the polyphenols and fiber present in wild blueberries. This study evaluated the modulation of the most common and abundant bifidobacterial taxonomic groups inhabiting the human gut in the same fecal samples. The analyses carried out showed that B. adolescentis, B. breve, B. catenulatum/pseudocatelulatum, and B. longum subsp. longum were always present in the group of subjects enrolled, whereas B. bifidum and B. longum subsp. infantis were not. Furthermore, it was found that the most predominant bifidobacterial species were B. longum subsp. longum and B. adolescentis. The results obtained revealed a high interindividual variability; however, a significant increase of B. longum subsp. infantis cell concentration was observed in the feces of volunteers after the wild blueberry drink treatment. This bifidobacterial group was shown to possess immunomodulatory abilities and to relieve symptoms and promote the regression of several gastrointestinal disorders. Thus, an increased cell concentration of B. longum subsp. infantis in the human gut could be considered of potential health benefit. In conclusion, wild blueberry consumption resulted in a specific bifidogenic effect that could positively affect certain populations of bifidobacteria with demonstrated health-promoting properties.
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Several human and animal studies have indicated that consumption of fruit and vegetables leads to increased microbial diversity and function, a shift in the abundance of bacterial phyla, growth of beneficial bacteria, such as Bifidobacterium and Lactobacillus, and reduction in potentially harmful bacteria, including E. coli and Enterococcus.
“Several human and animal studies have indicated that consumption of fruit and vegetables leads to increased microbial diversity and function, a shift in the abundance of bacterial phyla, growth of beneficial bacteria, such as Bifidobacterium and Lactobacillus, and reduction in potentially harmful bacteria, including E. coli and Enterococcus (51)(52)(53)(54)(55).”
From Diet and the Microbiota–Gut–Brain Axis: Sowing the Seeds of Good Mental Health (2021) · cites this paper as [52]
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- Authors
- Guglielmetti, S., Fracassetti, D., Taverniti, V., Del Bo’, C., Vendrame, S., Klimis-Zacas, D., Arioli, S., Riso, P., & Porrini, M.
- Affiliations
- University of Milan (IT)
- University of Maine (US)
- Department of Food Science and Human Nutrition, University of Maine, Orono, Maine 04469, United States
- Corresponding author
- Guglielmetti, Simone
- ORCID
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2013-08-19
- Volume
- 61
- Issue
- 34
- Pages
- 8134-8140
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W2325693693
- Cited by
- 123
- References
- 53
- Citations by year
- 2026: 4 · 2025: 8 · 2024: 9 · 2023: 8 · 2022: 13 · 2021: 10 · 2020: 15 · 2019: 10 · 2018: 11 · 2017: 9 · 2016: 5 · 2015: 13 · 2014: 7 · 2013: 1
- FWCI
- 3.88
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Agricultural and Food Chemistry (publishedVersion)
- PubMed (publishedVersion)
- BOA (University of Milano-Bicocca) (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
- Keywords
- Bifidobacterium, Vaccinium angustifolium, bifidogenic effect, gut microbiota, Bifidobacterium longum subsp. infantis, Bifidobacterium adolescentis, Bifidobacterium longum subsp. longum, Bifidobacterium catenulatum, dietary polyphenols, dietary fiber, interindividual variability, fecal microbiota, health benefits of probiotics
- MeSH terms
- Adult, Beverages, Bifidobacterium, Feces, Humans, Intestines, Male, Middle Aged, Blueberry Plants, Biodiversity
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