Cited by 668Bone Metabolism and DiseasesAlkaline Phosphatase Research StudiesBone and Dental Protein Studies

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Genetic Control of Bone Formation

Karsenty, Gerard, Kronenberg, Henry M., Settembre, Carmine·2009·Annual Review of Cell and Developmental Biology

DOI 10.1146/annurev.cellbio.042308.113308

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Abstract

In the past few years, our molecular understanding of bone formation has continued to increase. This review aims to present a comprehensive view of the current state of knowledge in the field. Thus, it will cover our current knowledge of chondrogenesis and osteoblastogenesis. It will also cover the most salient aspects of osteoblast function.

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Authors: Karsenty, G., Kronenberg, H. M., & Settembre, C.
Affiliations: Department of Genetics and Development, College of Physicians and Surgeons, Columbia University, New York, New York 10032;
Harvard University (US)
Columbia University (US)
ORCID: Kronenberg, Henry M.
Settembre, Carmine
Venue: Annual Review of Cell and Developmental Biology
Publisher: Annual Reviews
Published: 2009-11-01
Volume: 25
Issue: 1
Pages: 629-648
ISSN: 1081-0706 (ISSN-L)
1530-8995
DOI: 10.1146/annurev.cellbio.042308.113308
OpenAlex: W2149193631
Cited by: 667
References: 116
Citations by year: 2026: 21 · 2025: 22 · 2024: 23 · 2023: 29 · 2022: 28 · 2021: 35 · 2020: 61 · 2019: 42 · 2018: 49 · 2017: 47 · 2016: 57 · 2015: 59 · 2014: 51 · 2013: 38 · 2012: 46
FWCI: 2.70
Type: journal article
Language: en
Open access: closed
Locations: Annual Review of Cell and Developmental Biology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health
National Institute of Diabetes and Digestive and Kidney Diseases (R01DK067936)
National Institute of Dental and Craniofacial Research (R01DE011290)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bone Metabolism and Diseases
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Alkaline Phosphatase Research Studies
Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Bone and Dental Protein Studies
Keywords: bone formation, chondrogenesis, osteoblastogenesis, osteoblast activity, genetic control, skeletal development, osteogenic differentiation
MeSH terms: Animals, Humans, Osteoblasts, Osteogenesis, Transcription Factors, Gene Expression Regulation, Developmental, Chondrogenesis

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Genetic Control of Bone Formation

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