Mechanisms of Liver Injury. I. TNF-α-induced liver injury: role of IKK, JNK, and ROS pathways

Missing Pieces in the NF-κB Puzzle

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Role of tumor necrosis factor-alpha in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat.

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Induction of gadd45β by NF-κB downregulates pro-apoptotic JNK signalling

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The E3 Ubiquitin Ligase Itch Couples JNK Activation to TNFα-induced Cell Death by Inducing c-FLIPL Turnover

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IKKβ Is Required for Prevention of Apoptosis Mediated by Cell-Bound but Not by Circulating TNFα

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Reparative inflammation takes charge of tissue regeneration

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Necrosis, a well-orchestrated form of cell demise: Signalling cascades, important mediators and concomitant immune response

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Apoptosis and necroptosis in the liver: a matter of life and death

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Molecular mechanisms of lipotoxicity and glucotoxicity in nonalcoholic fatty liver disease

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Control of cccDNA function in hepatitis B virus infection

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Hepatocyte Death: A Clear and Present Danger

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Mutual cross-talk between reactive oxygen species and nuclear factor-kappa B: molecular basis and biological significance

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Absence of receptor interacting protein kinase 3 prevents ethanol-induced liver injury

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NLRP3 inflammasome driven liver injury and fibrosis: roles of IL-17 and TNF in mice

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Mechanisms of liver disease: cross-talk between the NF-κB and JNK pathways

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Translocation of iron from lysosomes into mitochondria is a key event during oxidative stress-induced hepatocellular injury

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Macrophage autophagy limits acute toxic liver injury in mice through down regulation of interleukin-1β

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Critical role of tumor necrosis factor receptor 1, but not 2, in hepatic stellate cell proliferation, extracellular matrix remodeling, and liver fibrogenesis

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Secreted Factors of Human Liver-Derived Mesenchymal Stem Cells Promote Liver Regeneration Early After Partial Hepatectomy

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Crosstalk between plasma cytokines, inflammation, and liver damage as a new strategy to monitoring NAFLD progression

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Markers of liver regeneration—the role of growth factors and cytokines: a systematic review

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Expression Pattern, Regulation, and Functions of Methionine Adenosyltransferase 2β Splicing Variants in Hepatoma Cells

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Anti-Inflammatory Effect of Resveratrol in Old Mice Liver

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Macrophage-Derived Cathepsin S Remodels the Extracellular Matrix to Promote Liver Fibrogenesis

Zuo, T., Xie, Q., Liu, J., Yang, J., Shi, J., Kong, D., Wang, Y., Zhang, Z., Gao, H., Zeng, D.-B., et al. (2023) · Gastroenterology · doi:10.1053/j.gastro.2023.05.039 · Cited by 70

Accelerated hepatocellular carcinoma development in mice expressing the Pim-3 transgene selectively in the liver

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Trovafloxacin Enhances TNF-Induced Inflammatory Stress and Cell Death Signaling and Reduces TNF Clearance in a Murine Model of Idiosyncratic Hepatotoxicity

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A novel bioscaffold with naturally-occurring extracellular matrix promotes hepatocyte survival and vessel patency in mouse models of heterologous transplantation

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Hepatotoxicity mediated by pyrazole (cytochrome P450 2E1) plus tumor necrosis factor alpha treatment occurs in c-Jun N-terminal kinase 2-/- but not in c-Jun N-terminal kinase 1−/− mice

Wang, X., Wu, D., Yang, L., & Cederbaum, A. I. (2011) · Hepatology · doi:10.1002/hep.24540 · Cited by 19

Complement-5 Inhibition Deters Progression of Fulminant Hepatitis to Acute Liver Failure in Murine Models

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Hepatotoxicity of FDA-approved small molecule kinase inhibitors

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