The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Selective muscle hypertrophy, changes in EMG and force, and serum hormones during strength training in older women
Abstract
Effects of strength training (ST) for 21 wk were examined in 10 older women (64 ± 3 yr). Electromyogram, maximal isometric force, one-repetition maximum strength, and rate of force development of the leg extensors, muscle cross-sectional area (CSA) of the quadriceps femoris (QF) and of vastus lateralis (VL), medialis (VM), intermedius (VI) and rectus femoris (RF) throughout the lengths of 3/12–12/15 (Lf) of the femur, muscle fiber proportion and areas of types I, IIa, and IIb of the VL were evaluated. Serum hormone concentrations of testosterone, growth hormone (GH), cortisol, and IGF-I were analyzed for the resting, preexercise, and postexercise conditions. After the 21-wk ST, maximal force increased by 37% ( P < 0.001) and 1-RM by 29% ( P < 0.001), accompanied by an increase ( P < 0.01) in rate of force development. The integrated electromyograms of the vastus muscles increased ( P < 0.05). The CSA of the total QF increased ( P < 0.05) throughout the length of the femur by 5–9%. The increases were significant ( P< 0.05) at 7/15–12/15 Lf for VL and at 3/15–8/15 Lf for VM, at 5/15–9/15 for VI and at 9/15 ( P < 0.05) for RF. The fiber areas of type I ( P < 0.05), IIa ( P < 0.001), and IIb ( P < 0.001) increased by 22–36%. No changes occurred during ST in serum basal concentrations of the hormones examined, but the level of testosterone correlated with the changes in the CSA of the QF ( r = 0.64, P < 0.05). An acute increase of GH ( P < 0.05), remaining elevated up to 30 min ( P < 0.05) postloading, was observed only at posttraining. Both neural adaptations and the capacity of skeletal muscle to undergo training-induced hypertrophy even in older women explain the strength gains. The increases in the CSA of the QF occurred throughout its length but differed selectively between the individual muscles. The serum concentrations of hormones remained unaltered, but a low level of testosterone may be a limiting factor in training-induced muscle hypertrophy. The magnitude and time duration of the acute GH response may be important physiological indicators of anabolic adaptations during strength training even in older women.
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Cites
High-Intensity Strength Training in Nonagenarians: Effects on Skeletal Muscle
Fiatarone, M. A. (1990) · JAMA · doi:10.1001/jama.1990.03440220053029 · Cited by 1,593
Leg extensor power and functional performance in very old men and women.
Bassey, E. J., Fiatarone, M. A., O'neill, E. F., Kelly, M., Evans, W. J., & Lipsitz, L. A. (1992) · Clinical Science · doi:10.1042/cs0820321 · Cited by 943
Skeletal muscle adaptations during early phase of heavy-resistance training in men and women.
Staron, R. S., Karapondo, D. L., Kraemer, W. J., Fry, A. C., Gordon, S. E., Falkel, J. E., Hagerman, F. C., & Hikida, R. S. (1994) · Journal of Applied Physiology · doi:10.1152/jappl.1994.76.3.1247 · Cited by 796
Kraemer, W. J., Patton, J. F., Gordon, S. E., Harman, E. A., Deschenes, M. R., Reynolds, K., Newton, R. U., Triplett, N. T., & Dziados, J. E. (1995) · Journal of Applied Physiology · doi:10.1152/jappl.1995.78.3.976 · Cited by 782 · cited 1×
“Type II subtype transformation, going from type IIb to IIab to IIa, has been previously observed in younger (1, 27, 40, 41) and older men (18) but Table 3.”
BackgroundSelf-citationHakkinen, K., Newton, R. U., Gordon, S. E., McCormick, M., Volek, J. S., Nindl, B. C., Gotshalk, L. A., Campbell, W. W., Evans, W. J., Hakkinen, A., et al. (1998) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/53a.6.b415 · Cited by 423
Self-citationPotential for gross muscle hypertrophy in older men
Moritani, T., & Devries, H. A. (1980) · Journal of Gerontology · doi:10.1093/geronj/35.5.672 · Cited by 362 · cited 1×
“This might primarily result from considerable neural adaptations observed, especially during the earlier weeks of training (16, 32), as indicated by large increases in maximal electromyographic (EMG) activity of trained agonist muscles associated with decreases in the coactivation of the antagonists especially in olde…”
Background(2000) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/55.2.b95 · Cited by 255
Self-citationNicklas, B., Ryan, A., Treuth, M., Harman, S., Blackman, M., Hurley, B., & Rogers, M. (1995) · International Journal of Sports Medicine · doi:10.1055/s-2007-973035 · Cited by 126
HÄKKINEN, K., & PAKARINEN, A. (1993) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1993.tb09549.x · Cited by 120
Self-citationStrength improvements with 1 yr of progressive rsistance training in older women
MORGANTI, C. M., NELSON, M. E., FIATARONE, M. A., DALLAL, G. E., ECONOMOS, C. D., CRAWFORD, B. M., & EVANS, W. J. (1995) · Medicine & Science in Sports & Exercise · doi:10.1249/00005768-199506000-00017 · Cited by 114
HÄKKINEN, K., & PAKARINEN, A. (1994) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1994.tb09678.x · Cited by 95
Pyka, G., Taaffe, D., & Marcus, R. (1994) · Hormone and Metabolic Research · doi:10.1055/s-2007-1001697 · Cited by 73 · cited 3×
“However, skeletal muscles of older people of both genders seem to retain the capacity to undergo training-induced hypertrophy provided that the volume, intensity, and the duration of the training period are sufficient (7, 12, 13, 17, 18, 37).”
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Cited by
Rate of force development: physiological and methodological considerations
Maffiuletti, N. A., Aagaard, P., Blazevich, A. J., Folland, J., Tillin, N., & Duchateau, J. (2016) · European Journal of Applied Physiology · doi:10.1007/s00421-016-3346-6 · Cited by 1,424
Folland, J. P., & Williams, A. G. (2007) · Sports Medicine · doi:10.2165/00007256-200737020-00004 · Cited by 1,347
Fragala, M. S., Cadore, E. L., Dorgo, S., Izquierdo, M., Kraemer, W. J., Peterson, M. D., & Ryan, E. D. (2019) · Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000003230 · Cited by 1,290
Self-citationCadore, E. L., Rodríguez-Mañas, L., Sinclair, A., & Izquierdo, M. (2013) · Rejuvenation Research · doi:10.1089/rej.2012.1397 · Cited by 954
Resistance exercise for muscular strength in older adults: a meta-analysis
Peterson, M. D., Rhea, M. R., Sen, A., & Gordon, P. M. (2010) · Ageing Research Reviews · doi:10.1016/j.arr.2010.03.004 · Cited by 808
Metadata
- Authors
- Häkkinen, K., Pakarinen, A., Kraemer, W. J., Häkkinen, A., Valkeinen, H., & Alen, M.
- Venue
- Journal of Applied Physiology
- Publisher
- American Physiological Society
- Published
- 2001-08-01
- Volume
- 91
- Issue
- 2
- Pages
- 569-580
- ISSN
- 0161-7567 (ISSN-L)
- 8750-7587
- 1522-1601
- OpenAlex
- W1953337947
- Cited by
- 367
- References
- 12
- FWCI
- 12.06
- Type
- journal article
- Language
- en
- Open access
- closed
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