Visual Scene Processing in Familiar and Unfamiliar Environments
Abstract
Humans and animals use information obtained from the local visual scene to orient themselves in the wider world. Although neural systems involved in scene perception have been identified, the extent to which processing in these systems is affected by previous experience is unclear. We addressed this issue by scanning subjects with functional magnetic resonance imaging (fMRI) while they viewed photographs of familiar and unfamiliar locations. Scene-selective regions in parahippocampal cortex (the parahippocampal place area, or PPA), retrosplenial cortex (RSC), and the transverse occipital sulcus (TOS) responded more strongly to images of familiar locations than to images of unfamiliar locations with the strongest effects (>50% increase) in RSC. Examination of fMRI repetition suppression (RS) effects indicated that images of familiar and unfamiliar locations were processed with the same degree of viewpoint specificity; however, increased viewpoint invariance was observed as individual scenes became more familiar over the course of a scan session. Surprisingly, these within-scan-session viewpoint-invariant RS effects were only observed when scenes were repeated across different trials but not when scenes were repeated within a trial, suggesting that within- and between-trial RS effects may index different aspects of visual scene processing. The sensitivity to environmental familiarity observed in the PPA, RSC, and TOS supports earlier claims that these regions mediate the extraction of navigationally relevant spatial information from visual scenes. As locations become familiar, the neural representations of these locations become enriched, but the viewpoint invariance of these representations does not change.
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RSC responds strongly during passive viewing of environmental scenes in fMRI studies, especially when the scenes depict familiar places.
“It responds strongly during passive viewing of environmental scenes in fMRI studies, especially when the scenes depict familiar places24.”
From Anchoring the neural compass: coding of local spatial reference frames in human medial parietal lobe (2014) · cites this paper as [24]
Cites
Marr, D. (1982) · Cumulative Index of Computer Aided Architectural Design · Cited by 5,733 · see citing works
Recognition-by-components: A theory of human image understanding.
Biederman, I. (1987) · Psychological Review · doi:10.1037/0033-295x.94.2.115 · Cited by 5,621 · see citing works
A cortical representation of the local visual environment
Epstein, R. A., & Kanwisher, N. (1998) · Nature · doi:10.1038/33402 · Cited by 2,960 · see citing works
Self-citationRepetition and the brain: neural models of stimulus-specific effects
Grill-Spector, K., Henson, R., & Martin, A. (2006) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2005.11.006 · Cited by 2,256 · see citing works
Synaptic depression and cortical gain control
Abbott, L. F., Varela, J. A., Sen, K., & Nelson, S. B. (1997) · Science · doi:10.1126/science.275.5297.221 · Cited by 1,690 · see citing works
Bar, M. (2004) · Nature Reviews Neuroscience · doi:10.1038/nrn1476 · Cited by 1,613 · see citing works
Knowing Where and Getting There: A Human Navigation Network
Maguire, E. A., Burgess, N., Donnett, J. G., Frackowiak, R. S. J., Frith, C. D., & O'Keefe, J. (1998) · Science · doi:10.1126/science.280.5365.921 · Cited by 1,303 · see citing works
Kalanit Grill-spector, A., Kushnir, T., Edelman, S., Avidan, G., Itzchak, Y., & Malach, R. (1999) · Neuron · doi:10.1016/s0896-6273(00)80832-6 · Cited by 1,156 · see citing works
fMR-adaptation: a tool for studying the functional properties of human cortical neurons
Kalanit Grill-spector, A., & Malach, R. (2001) · Acta Psychologica · doi:10.1016/s0001-6918(01)00019-1 · Cited by 1,068 · see citing works
Mental Imagery of Faces and Places Activates Corresponding Stimulus-Specific Brain Regions
O’Craven, K. M., & Kanwisher, N. (2000) · Journal of Cognitive Neuroscience · doi:10.1162/08989290051137549 · Cited by 1,057 · see citing works
Neural mechanisms for visual memory and their role in attention
Desimone, R. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.24.13494 · Cited by 1,028 · cited 1× · see citing works
“They hypothesized that between-trial effects might be caused by a " sharpening " of object representations as neurons that encode nonessential features drop out of the representation, leading to reduced response (and faster reaction times) for repeated items (Desimone 1996; Wiggs and Martin 1998).”
Henderson, J. M., & Hollingworth, A. (1999) · Annual Review of Psychology · doi:10.1146/annurev.psych.50.1.243 · Cited by 971 · see citing works
Demb, J. B., Desmond, J., Wagner, A., Vaidya, C. J., Glover, G. H., & Gabrieli, J. D. E. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-09-05870.1995 · Cited by 911 · see citing works
Properties and mechanisms of perceptual priming
Wiggs, C. L., & Martin, A. D. (1998) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(98)80144-x · Cited by 852 · see citing works
Role of schemata in memory for places
Brewer, W. F., & Treyens, J. C. (1981) · Cognitive Psychology · doi:10.1016/0010-0285(81)90008-6 · Cited by 839 · see citing works
Schacter, D. L., & Buckner, R. L. (1998) · Neuron · doi:10.1016/s0896-6273(00)80448-1 · Cited by 837 · see citing works
The Parahippocampal Place Area
Epstein, R. A., Harris, A. M., Stanley, D. A., & Kanwisher, N. (1999) · Neuron · doi:10.1016/s0896-6273(00)80758-8 · Cited by 819 · see citing works
Self-citationTopographical disorientation: a synthesis and taxonomy
Aguirre, G. K. (1999) · Brain · doi:10.1093/brain/122.9.1613 · Cited by 772 · see citing works
Center–periphery organization of human object areas
Levy, I., Hasson, U., Avidan, G., Hendler, T., & Malach, R. (2001) · Nature Neuroscience · doi:10.1038/87490 · Cited by 687 · see citing works
Recalling Routes around London: Activation of the Right Hippocampus in Taxi Drivers
Maguire, E. A., Frackowiak, R. S. J., & Frith, C. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-18-07103.1997 · Cited by 655 · see citing works
Neuroimaging Evidence for Dissociable Forms of Repetition Priming
Henson, R. N., Shallice, T., & Dolan, R. J. (2000) · Science · doi:10.1126/science.287.5456.1269 · Cited by 638 · see citing works
The Parahippocampus Subserves Topographical Learning in Man
Aguirre, G. K., Detre, J. A., Alsop, D. C., & D’Esposito, M. (1996) · Cerebral Cortex · doi:10.1093/cercor/6.6.823 · Cited by 622 · see citing works
Buckner, R. L., Goodman, J. M., Burock, M. A., Rotte, M., Koutstaal, W., Schacter, D. L., Rosen, B. R., & Dale, A. M. (1998) · Neuron · doi:10.1016/s0896-6273(00)80456-0 · Cited by 622 · see citing works
The retrosplenial contribution to human navigation: a review of lesion and neuroimaging findings
Maguire, E. (2001) · Scandinavian Journal of Psychology · doi:10.1111/1467-9450.00233 · Cited by 584 · see citing works
The neural basis of object perception
Kalanit Grill-spector, A. (2003) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(03)00040-0 · Cited by 562 · see citing works
The representation of stimulus familiarity in anterior inferior temporal cortex
Li, L., Miller, E. K., & Desimone, R. (1993) · Journal of Neurophysiology · doi:10.1152/jn.1993.69.6.1918 · Cited by 539 · see citing works
Bohbot, V. D., Kalina, M., Stepankova, K., Spackova, N., Petrides, M., & Nadel, L. (1998) · Neuropsychologia · doi:10.1016/s0028-3932(97)00161-9 · Cited by 516 · see citing works
Multiple levels of visual object constancy revealed by event-related fMRI of repetition priming
Vuilleumier, P. O., Henson, R. N., Driver, J., & Dolan, R. J. (2002) · Nature Neuroscience · doi:10.1038/nn839 · Cited by 505 · see citing works
A temporoparietal and prefrontal network for retrieving the spatial context of lifelike events
Burgess, N., Maguire, E. A., Spiers, H. J., & O'Keefe, J. (2001) · NeuroImage · doi:10.1006/nimg.2001.0806 · Cited by 502 · see citing works
Mental navigation along memorized routes activates the hippocampus, precuneus, and insula
Ghaëm, O., Mellet, E., Crivello, F., Tzourio‐Mazoyer, N., Mazoyer, B. M., Berthoz, A., & Denis, M. (1997) · Neuroreport · doi:10.1097/00001756-199702100-00032 · Cited by 477 · see citing works
View-invariant representations of familiar objects by neurons in the inferior temporal visual cortex
Booth, M. J. (1998) · Cerebral Cortex · doi:10.1093/cercor/8.6.510 · Cited by 464 · see citing works
Rapid Adaptation in Visual Cortex to the Structure of Images
Müller, J. R., Metha, A. B., Krauskopf, J., & Lennie, P. (1999) · Science · doi:10.1126/science.285.5432.1405 · Cited by 458 · see citing works
Cabeza, R. E. L., Prince, S. E., Daselaar, S. M., Greenberg, D. L., Budde, M. D., Dolcos, F., LaBar, K. S., & Rubin, D. C. (2004) · Journal of Cognitive Neuroscience · doi:10.1162/0898929042568578 · Cited by 377 · see citing works
A Tonic Hyperpolarization Underlying Contrast Adaptation in Cat Visual Cortex
Carandini, M., & Ferster, D. (1997) · Science · doi:10.1126/science.276.5314.949 · Cited by 372 · see citing works
Selective neural representation of objects relevant for navigation
Janzen, G., & van Turennout, M. (2004) · Nature Neuroscience · doi:10.1038/nn1257 · Cited by 372 · see citing works
Viewpoint-Specific Scene Representations in Human Parahippocampal Cortex
Epstein, R., Graham, K. S., & Downing, P. E. (2003) · Neuron · doi:10.1016/s0896-6273(03)00117-x · Cited by 360 · see citing works
Self-citationLarge-scale mirror-symmetry organization of human occipito-temporal object areas
Hasson, U., Harel, M., Levy, I., & Malach, R. (2003) · Neuron · doi:10.1016/s0896-6273(03)00144-2 · Cited by 336 · see citing works
Pure Topographical Disorientation: A Definition and Anatomical Basis
Habib, M., & Angela Sirigu, B. (1987) · Cortex · doi:10.1016/s0010-9452(87)80020-5 · Cited by 335 · see citing works
Sawamura, H., Orban, G. A., & Vogels, R. (2006) · Neuron · doi:10.1016/j.neuron.2005.11.028 · Cited by 331 · see citing works
Pure topographic disorientation due to right retrosplenial lesion
Takahashi, N., Kawamura, M., Shiota, J., Kasahata, N., & Hirayama, K. (1997) · Neurology · doi:10.1212/wnl.49.2.464 · Cited by 319 · see citing works
Cortical activity reductions during repetition priming can result from rapid response learning
Dobbins, I. G., Schnyer, D. M., Verfaellie, M. H., & Schacter, D. L. (2004) · Nature · doi:10.1038/nature02400 · Cited by 314 · see citing works
Wolbers, T., & Büchel, C. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.4705-04.2005 · Cited by 301 · see citing works
Rosenbaum, R. S., Ziegler, M., Winocur, G., Grady, C. L., & Moscovitch, M. (2004) · Hippocampus · doi:10.1002/hipo.10218 · Cited by 258 · see citing works
Differential Effects of Viewpoint on Object-Driven Activation in Dorsal and Ventral Streams
James, T. W., Humphrey, G. K., Gati, J. S., Menon, R. S., & Goodale, M. A. (2002) · Neuron · doi:10.1016/s0896-6273(02)00803-6 · Cited by 251 · see citing works
Three-dimensional object recognition is viewpoint dependent
Tarr, M. J., Williams, P., Hayward, W. G., & Gauthier, L. (1998) · Nature Neuroscience · doi:10.1038/1089 · Cited by 246 · see citing works
Reductions in neural activity underlie behavioral components of repetition priming
Wig, G. S., Grafton, S. T., Demos, K. E., & Kelley, W. M. (2005) · Nature Neuroscience · doi:10.1038/nn1515 · Cited by 223 · see citing works
Orientation-Tuned fMRI Adaptation in Human Visual Cortex
Fang, F., Murray, S. O., Kersten, D., & He, S. (2005) · Journal of Neurophysiology · doi:10.1152/jn.00378.2005 · Cited by 184 · see citing works
Viewer-Centered Object Representation in the Human Visual System Revealed by Viewpoint Aftereffects
Fang, F., & He, S. (2005) · Neuron · doi:10.1016/j.neuron.2005.01.037 · Cited by 182 · see citing works
Eger, E., Schweinberger, S. R., Dolan, R. J., & Henson, R. N. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.03.010 · Cited by 180 · see citing works
Sugiura, M., Shah, N. J., Zilles, K., & Fink, G. R. (2005) · Journal of Cognitive Neuroscience · doi:10.1162/0898929053124956 · Cited by 167 · see citing works
Epstein, R. A., & Higgins, J. S. (2006) · Cerebral Cortex · doi:10.1093/cercor/bhl079 · Cited by 152 · see citing works
Self-citationNeuropsychological evidence for a topographical learning mechanism in parahippocampal cortex
Epstein, R. A., DeYoe, E. A., Press, D. Z., Rosen, A. C., & Kanwisher, N. (2001) · Cognitive Neuropsychology · doi:10.1080/02643290125929 · Cited by 151 · see citing works
Self-citationEpstein, R. A., Higgins, J. S., & Thompson‐Schill, S. L. (2005) · Journal of Cognitive Neuroscience · doi:10.1162/0898929052879987 · Cited by 149 · see citing works
Self-citationThe cortical basis of visual scene processing
Epstein, R. A. (2005) · Visual Cognition · doi:10.1080/13506280444000607 · Cited by 137 · see citing works
Self-citationObject-Selective Cortex Exhibits Performance-Independent Repetition Suppression
Sayres, R., & Kalanit Grill-spector, A. (2005) · Journal of Neurophysiology · doi:10.1152/jn.00500.2005 · Cited by 137 · see citing works
The representation of visual scenes
Intraub, H. (1997) · Trends in Cognitive Sciences · doi:10.1016/s1364-6613(97)01067-x · Cited by 134 · see citing works
Repetition‐induced changes in BOLD response reflect accumulation of neural activity
James, T. W., & Gauthier, L. (2005) · Human Brain Mapping · doi:10.1002/hbm.20165 · Cited by 131 · see citing works
Mental navigation in humans is processed in the anterior bank of the parieto-occipital sulcus
Ino, T., Inoue, Y., Kage, M., Hirose, S., Kimura, T., & Fukuyama, H. (2002) · Neuroscience Letters · doi:10.1016/s0304-3940(02)00019-8 · Cited by 116 · see citing works
Agnosia for scenes in topographagnosia
Mendez, M. F., & Cherrier, M. M. (2003) · Neuropsychologia · doi:10.1016/s0028-3932(03)00041-1 · Cited by 105 · see citing works
Pure Topographical Disorientation Due to Right Posterior Cingulate Lesion
KATAYAMA, K., TAKAHASHI, N., OGAWARA, K., & HATTORI, T. (1999) · Cortex · doi:10.1016/s0010-9452(08)70801-3 · Cited by 99 · see citing works
Implicit scene learning is viewpoint dependent
Chua, K.-P., & Chun, M. M. (2003) · Perception & Psychophysics · doi:10.3758/bf03194784 · Cited by 95 · see citing works
Ewbank, M., Schluppeck, D., & Andrews, T. J. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.06.036 · Cited by 80 · see citing works
Selectivity of Adaptation in Single Units: Implications for fMRI Experiments
Kalanit Grill-spector, A. (2006) · Neuron · doi:10.1016/j.neuron.2006.01.004 · Cited by 61 · see citing works
Boundary extension: Filling-out scene layout information in human parahippocampal cortex
Park, S., Intraub, H., Widders, D. M., Yi, D.-J., & Chun, M. M. (2010) · Journal of Vision · doi:10.1167/6.6.802 · Cited by 1 · see citing works
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Epstein, R. A. (2008) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2008.07.004 · Cited by 928 · see citing works
Self-citationWinocur, G., Moscovitch, M., & Bontempi, B. (2010) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2010.04.016 · Cited by 486 · see citing works
Neural representation of abstract and concrete concepts: A meta‐analysis of neuroimaging studies
Wang, J., Conder, J. A., Blitzer, D. N., & Shinkareva, S. V. (2010) · Human Brain Mapping · doi:10.1002/hbm.20950 · Cited by 427 · see citing works
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Epstein, R. A., & Baker, C. I. (2019) · Annual Review of Vision Science · doi:10.1146/annurev-vision-091718-014809 · Cited by 350 · see citing works
Self-citationLithfous, S., Dufour, A., & Després, O. (2012) · Ageing Research Reviews · doi:10.1016/j.arr.2012.04.007 · Cited by 349 · see citing works
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Epstein, R. A., Parker, W. E., & Feiler, A. M. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0799-07.2007 · Cited by 331 · see citing works
Self-citationAnchoring the neural compass: coding of local spatial reference frames in human medial parietal lobe
Marchette, S. A., Vass, L. K., Ryan, J., & Epstein, R. A. (2014) · Nature Neuroscience · doi:10.1038/nn.3834 · Cited by 287 · see citing works
Self-citationReal-World Scene Representations in High-Level Visual Cortex: It's the Spaces More Than the Places
Kravitz, D. J., Peng, C. S., & Baker, C. I. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.4588-10.2011 · Cited by 284 · see citing works
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Martinelli, P., Sperduti, M., & Piolino, P. (2013) · Human Brain Mapping · doi:10.1002/hbm.22008 · Cited by 281 · see citing works
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Walther, D. B., Chai, B., Caddigan, E., Beck, D. M., & Fei-Fei, L. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1015666108 · Cited by 235 · see citing works
The neural bases of spatial frequency processing during scene perception
Kauffmann, L., Ramanoël, S., & Peyrin, C. (2014) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2014.00037 · Cited by 210 · see citing works
Park, S., & Chun, M. M. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.04.058 · Cited by 209 · see citing works
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Bonner, M., & Epstein, R. A. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1618228114 · Cited by 198 · see citing works
Self-citationRetrosplenial cortex codes for permanent landmarks
Auger, S. D., Mullally, S. L., & Maguire, E. A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0043620 · Cited by 205 · see citing works
Egocentric boundary vector tuning of the retrosplenial cortex
Alexander, A. S., Carstensen, L. C., Hinman, J. R., Raudies, F., Chapman, G. W., & Hasselmo, M. E. (2020) · Science Advances · doi:10.1126/sciadv.aaz2322 · Cited by 197 · see citing works
Stevens, W. D., Buckner, R. L., & Schacter, D. L. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhp270 · Cited by 188 · see citing works
Cavina‐Pratesi, C., Kentridge, R. W., Heywood, C. A., & Milner, A. D. (2010) · Cerebral Cortex · doi:10.1093/cercor/bhp298 · Cited by 179 · see citing works
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Epstein, R. A., & Vass, L. K. (2013) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2012.0533 · Cited by 168 · see citing works
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He, C., Peelen, M. V., Han, Z., Lin, N., Caramazza, A., & Bi, Y. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.04.051 · Cited by 121 · see citing works
A network linking scene perception and spatial memory systems in posterior cerebral cortex
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Self-citationNeural correlates of real-world route learning
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Self-citationComputational mechanisms underlying cortical responses to the affordance properties of visual scenes
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Self-citationLe, T. M., Borghi, J., Kujawa, A., Klein, D. N., & Leung, H. (2017) · NeuroImage Clinical · doi:10.1016/j.nicl.2017.01.004 · Cited by 91 · see citing works
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MacEvoy, S. P., & Epstein, R. A. (2007) · Journal of Neurophysiology · doi:10.1152/jn.00438.2007 · Cited by 86 · see citing works
Self-citationInvolvement of retrosplenial cortex in forming associations between multiple sensory stimuli.
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Stevens, W. D., Kahn, I., Wig, G. S., & Schacter, D. L. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhr273 · Cited by 70 · see citing works
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A virtual reality-based FMRI study of reward-based spatial learning
Marsh, R., Hao, X., Xu, D., Wang, Z., Duan, Y., Liu, J., Kangarlu, A., Martínez, D., Garcia, F., Tau, G. Z., et al. (2010) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2010.05.033 · Cited by 61 · see citing works
Weibert, K., & Andrews, T. J. (2015) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2015.07.015 · Cited by 60 · see citing works
Cross‐cultural differences in eyewitness memory reports
Anakwah, N., Horselenberg, R., Hope, L., Amankwah‐Poku, M., & Koppen, P. J. V. (2020) · Applied Cognitive Psychology · doi:10.1002/acp.3637 · Cited by 57 · see citing works
An older view on distance perception: older adults perceive walkable extents as farther
Sugovic, M., & Witt, J. K. (2013) · Experimental Brain Research · doi:10.1007/s00221-013-3447-y · Cited by 55 · see citing works
Rethinking Space: A Review of Perception, Attention, and Memory in Scene Processing
Castelhano, M. S., & Krzyś, K. J. (2020) · Annual Review of Vision Science · doi:10.1146/annurev-vision-121219-081745 · Cited by 52 · see citing works
Ganaden, R. E., Mullin, C. R., & Steeves, J. K. E. (2013) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00372 · Cited by 50 · see citing works
Bettencourt, K. C., & Yaoda Xu, A. (2013) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00422 · Cited by 49 · see citing works
A Neural Basis for Developmental Topographic Disorientation
Kim, J. G., Aminoff, E., Kästner, S., & Behrmann, M. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.0640-15.2015 · Cited by 48 · see citing works
Choo, H., & Walther, D. B. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2016.04.021 · Cited by 50 · see citing works
Toward a conceptualization of retrohippocampal contributions to learning and memory
Bucci, D. J., & Robinson, S. (2014) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2014.05.007 · Cited by 47 · see citing works
Familiar environments enhance object and spatial memory in both younger and older adults
Merriman, N. A., Ondřej, J., Roudaia, E., O’Sullivan, C., & Newell, F. N. (2016) · Experimental Brain Research · doi:10.1007/s00221-016-4557-0 · Cited by 48 · see citing works
Category Selectivity for Face and Scene Recognition in Human Medial Parietal Cortex
Woolnough, O., Rollo, P. S., Forseth, K. J., Kadipasaoglu, C. M., Ekstrom, A. D., & Tandon, N. (2020) · Current Biology · doi:10.1016/j.cub.2020.05.018 · Cited by 45 · see citing works
Places in the Brain: Bridging Layout and Object Geometry in Scene-Selective Cortex
Dillon, M. R., Persichetti, A. S., Spelke, E. S., & Dilks, D. D. (2017) · Cerebral Cortex · doi:10.1093/cercor/bhx139 · Cited by 45 · see citing works
Amit, E., Mehoudar, E., Yaacov Trope, B., & Yovel, G. (2012) · Brain and Cognition · doi:10.1016/j.bandc.2012.06.006 · Cited by 46 · see citing works
Çukur, T., Huth, A. G., Nishimoto, S., & Gallant, J. L. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.4033-14.2016 · Cited by 44 · see citing works
Neural Systems for Visual Scene Recognition
Epstein, R. A. (2014) · The MIT Press eBooks · doi:10.7551/mitpress/9780262027854.003.0006 · Cited by 43 · see citing works
Self-citationLee, A. C. H., Brodersen, K. H., & Rudebeck, S. R. (2012) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00301 · Cited by 41 · see citing works
Coarse-to-fine Categorization of Visual Scenes in Scene-selective Cortex
Musel, B., Kauffmann, L., Ramanoël, S., Giavarini, C., Guyader, N., Chauvin, A., & Peyrin, C. (2014) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00643 · Cited by 40 · see citing works
Park, J., & Park, S. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.1991-19.2020 · Cited by 39 · see citing works
Miyakoshi, M., Gehrke, L., Gramann, K., Makeig, S., & Iversen, J. R. (2021) · European Journal of Neuroscience · doi:10.1111/ejn.15131 · Cited by 38 · see citing works
Neural structures and mechanisms involved in scene recognition: A review and interpretation
Sewards, T. V. (2010) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2010.11.018 · Cited by 39 · see citing works
Scene Perception and Visuospatial Memory Converge at the Anterior Edge of Visually Responsive Cortex
Steel, A., Garcia, B. D., Goyal, K., Mynick, A., & Robertson, C. E. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.2043-22.2023 · Cited by 38 · see citing works
Implications of neuroarchitecture for the experience of the built environment: a scoping review
Lee, S., Shin, W., & Park, E. J. (2022) · International Journal of Architectural Research Archnet-IJAR · doi:10.1108/arch-09-2021-0249 · Cited by 36 · see citing works
Regionally-specific adaptation dynamics in human object areas
Gilaie‐Dotan, S., Nir, Y., & Malach, R. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.10.010 · Cited by 35 · see citing works
Lewis, J. W., Talkington, W. J., Tallaksen, K. C., & Frum, C. (2012) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2012.00027 · Cited by 35 · see citing works
Furuya, Y., Matsumoto, J., Hori, E., Boas, C. V., Tran, A. H., Shimada, Y., Ono, T., & Nishijo, H. (2013) · Hippocampus · doi:10.1002/hipo.22209 · Cited by 31 · see citing works
Lewis, J. W., Frum, C., Brefczynski‐Lewis, J. A., Talkington, W. J., Walker, N. A., Rapuano, K. M., & Kovach, A. L. (2011) · Human Brain Mapping · doi:10.1002/hbm.21185 · Cited by 32 · see citing works
Age-Related Differences in Spatial Frequency Processing during Scene Categorization
Ramanoël, S., Kauffmann, L., Cousin, É., Dojat, M., & Peyrin, C. (2015) · PLoS ONE · doi:10.1371/journal.pone.0134554 · Cited by 30 · see citing works
Zweynert, S. (2011) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2011.00144 · Cited by 28 · see citing works
Early Electrophysiological Markers of Navigational Affordances in Scenes
Harel, A., Nador, J., Bonner, M., & Epstein, R. A. (2022) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_01810 · Cited by 26 · see citing works
Self-citationRefreshing and Integrating Visual Scenes in Scene-selective Cortex
Park, S., Chun, M. M., & Johnson, M. K. (2009) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2009.21406 · Cited by 26 · see citing works
Penaud, S., Jebara, N., Zaoui, M., Orriols, E., Berthoz, A., & Piolino, P. (2022) · Journal of Environmental Psychology · doi:10.1016/j.jenvp.2022.101801 · Cited by 22 · see citing works
Motion responses in scene-selective regions
Stark, D., & Bartels, A. (2015) · NeuroImage · doi:10.1016/j.neuroimage.2015.06.031 · Cited by 23 · see citing works
Sledge runner fasciculus: anatomic architecture and tractographic morphology
Koutsarnakis, C., Kalyvas, A., Skandalakis, G. P., Karavasilis, E., Christidi, F., Komaitis, S., Velonakis, G., Liakos, F., Emelifeonwu, J. A., Giavri, Z., et al. (2019) · Brain Structure and Function · doi:10.1007/s00429-018-01822-4 · Cited by 23 · see citing works
Neural representations of Groups and Stereotypes using fMRI repetition suppression
Delplanque, J., Heleven, E., & Overwalle, F. V. (2019) · Scientific Reports · doi:10.1038/s41598-019-39859-y · Cited by 23 · see citing works
Parsing rooms: the role of the PPA and RSC in perceiving object relations and spatial layout
Bilalić, M., Lindig, T. M., & Turella, L. (2019) · Brain Structure and Function · doi:10.1007/s00429-019-01901-0 · Cited by 22 · see citing works
Robin, J., Rivest, J., Rosenbaum, R. S., & Moscovitch, M. (2019) · Cortex · doi:10.1016/j.cortex.2019.04.013 · Cited by 21 · see citing works
Ferrara, K., & Landau, B. (2015) · Cognition · doi:10.1016/j.cognition.2015.07.010 · Cited by 19 · see citing works
Age and the Neural Network of Personal Familiarity
Donix, M., Petrowski, K., Jurjanz, L., Huebner, T., Herold, U., Bäumler, D., Amanatidis, E. C., Poettrich, K., Smolka, M. N., & Holthoff‐Detto, V. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015790 · Cited by 18 · see citing works
Bleau, M., Paré, S., Chebat, D., Kupers, R. C., Nemargut, J. P., & Ptito, M. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.1010354 · Cited by 17 · see citing works
Elshout, J. A., van den Berg, A. V., & Haak, K. V. (2018) · Journal of Vision · doi:10.1167/18.9.22 · Cited by 17 · see citing works
A network linking scene perception and spatial memory systems in posterior cerebral cortexPreprint
Steel, A., Billings, M. M., Silson, E. H., & Robertson, C. E. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.05.25.115147 · Cited by 18 · see citing works
Johnson, J. G., Sharkey, T., Butarbutar, I. C., Xiong, D., Huang, R., Sy, L. E., & Weibel, N. (2023) · CHI Conference on Human Factors in Computing Systems · doi:10.1145/3544548.3581444 · Cited by 16 · see citing works
Klink, H., KAISER, D. H., Stecher, R., Ambrus, G. G., & Kovács, G. (2023) · Cerebral Cortex · doi:10.1093/cercor/bhad397 · Cited by 16 · see citing works
Have you been there before? Decoding recognition of spatial scenes from fMRI signals in precuneus
Bogler, C., Zangrossi, A., Miller, C., Sartori, G., & Haynes, J. (2024) · Human Brain Mapping · doi:10.1002/hbm.26690 · Cited by 16 · see citing works
Noad, K. N., Watson, D. M., & Andrews, T. J. (2024) · Cerebral Cortex · doi:10.1093/cercor/bhae285 · Cited by 16 · see citing works
The role of place attachment and spatial anxiety in environmental knowledge
Pullano, L., Foti, F., Liuzza, M. T., & Palermo, L. (2024) · Journal of Environmental Psychology · doi:10.1016/j.jenvp.2024.102229 · Cited by 15 · see citing works
Ryals, A. J., Cleary, A. M., & Seger, C. A. (2012) · Brain Research · doi:10.1016/j.brainres.2012.10.068 · Cited by 15 · see citing works
Functional Imaging During Recognition of Personally Familiar Faces and Places in Alzheimer's Disease
Donix, M., Jurjanz, L., Meyer, S., Amanatidis, E. C., Bäumler, D., Huebner, T., Poettrich, K., Smolka, M. N., & Holthoff‐Detto, V. (2012) · Archives of Clinical Neuropsychology · doi:10.1093/arclin/acs093 · Cited by 15 · see citing works
Environment-based object values learned by local network in the striatum tail
Kunimatsu, J., Yamamoto, S., Maeda, K., & Hikosaka, O. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2013623118 · Cited by 12 · see citing works
Individual differences in internal models explain idiosyncrasies in scene perception
Wang, G., Foxwell, M. J., Cichy, R. M., Pitcher, D., & KAISER, D. H. (2024) · Cognition · doi:10.1016/j.cognition.2024.105723 · Cited by 12 · see citing works
van Assche, M., Kebets, V., Vuilleumier, P. O., & Assal, F. (2014) · Cerebral Cortex · doi:10.1093/cercor/bhu215 · Cited by 11 · see citing works
Selective scene perception deficits in a case of topographical disorientation
Robin, J., Lowe, M. X., Pishdadian, S., Rivest, J., Cant, J. S., & Moscovitch, M. (2017) · Cortex · doi:10.1016/j.cortex.2017.03.014 · Cited by 11 · see citing works
Steel, A., Prasad, D., Garcia, B. D., & Robertson, C. E. (2025) · Journal of Neuroscience · doi:10.1523/jneurosci.0028-25.2025 · Cited by 15 · see citing works
Nguyen, H. M., Matsumoto, J., Tran, A. H., Ono, T., & Nishijo, H. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00066 · Cited by 10 · see citing works
Welbourne, L. E., Jonnalagadda, A., Giesbrecht, B., & Eckstein, M. P. (2021) · Communications Biology · doi:10.1038/s42003-021-02294-9 · Cited by 10 · see citing works
- Authors
- Epstein, R. A., Higgins, J. S., Jablonski, K., & Feiler, A. M.
- Affiliations
- University of Pennsylvania (US)
- ORCID
- Epstein, Russell A.
- Venue
- Journal of Neurophysiology
- Publisher
- American Physiological Society
- Published
- 2007-05
- Volume
- 97
- Issue
- 5
- Pages
- 3670-3683
- ISSN
- 0022-3077 (ISSN-L)
- 1522-1598
- OpenAlex
- W2107417492
- Cited by
- 153
- References
- 64
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 11 · 2023: 7 · 2022: 5 · 2021: 10 · 2020: 9 · 2019: 8 · 2018: 5 · 2017: 5 · 2016: 10 · 2015: 10 · 2014: 10 · 2013: 9 · 2012: 15
- FWCI
- 3.34
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Neurophysiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Eye Institute (EY016464, R01EY016464)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Physical Sciences › Engineering › Automotive Engineering › Spatial Cognition and Navigation
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Keywords
- visual scene processing, environmental familiarity, parahippocampal place area, retrosplenial cortex, transverse occipital sulcus, repetition suppression, viewpoint invariance, spatial navigation, scene perception
- MeSH terms
- Brain Mapping, Environment, Female, Humans, Image Processing, Computer-Assisted, Functional Laterality, Magnetic Resonance Imaging, Male, Oxygen, Pattern Recognition, Visual, Photic Stimulation, Visual Cortex, Recognition, Psychology
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