The DOI matches its Crossref record.
Oscillatory activity in sensorimotor cortex of awake monkeys: synchronization of local field potentials and relation to behavior
Abstract
1. Oscillations of 20-40 Hz were observed in local field potentials (LFPs) and unit activity in sensorimotor cortices of three awake monkeys while the monkeys performed trained wrist movements and untrained exploratory arm movements. The mean frequency of LFP oscillations was 25.9 +/- 1.4 (SD) Hz and the number of cycles of oscillations per episode was variable, with a mean of 4.2 +/- 0.5 (mean +/- SE). 2. Oscillatory episodes occurred most often when the monkeys retrieved raisins from a Klüver board (0.59 +/- 0.23 episodes per s, mean +/- SD) or from unseen locations with the use of somatosensory feedback (0.62 +/- 0.12 episodes per s); they occurred less often when the monkeys performed repetitive wrist flexion and extension movements (0.22 +/- 0.04 episodes per s) or sat quietly at rest (0.23 +/- 0.17 episodes per s). 3. The amplitude of LFP oscillations increased with depth in cortex, reaching a maximum between 1 and 2 mm. LFP oscillations at the surface of the cortex were 180 degrees out of phase with oscillations in the deep cortical layers. The phase shift (with respect to the deep layers) decreased with depth in the cortex and disappeared at depths of > 1 mm. 4. LFPs were recorded simultaneously at multiple sites in the sensorimotor cortex when monkeys retrieved raisins from a Klüver board or from unseen locations. Cross-correlation of LFPs recorded at different sites indicated that oscillations in the 20- to 40-Hz range could become synchronized at sites separated by up to > or = 14 mm in the precentral cortex. 5. The probability of occurrence of significant correlations between LFP oscillations at paired sites and the average correlation amplitude decreased with increasing horizontal separation of sites in precentral cortex. The phase shift between LFP oscillations recorded at paired sites did not change significantly with increasing horizontal separation. 6. For paired sites in precentral cortex, the average strength of correlations and the proportion of oscillations that were significantly correlated were greater during exploratory behaviors such as retrieving raisins from slots of the Klüver board than during periods of rest or overtrained wrist movements. 7. Oscillations could become synchronized with small phase shifts (0.5 +/- 1.6 ms) between pre- and postcentral cortical sites. Average strength and probability of occurrence of significant correlations between pre- and postcentral LFPs increased during exploratory behaviors. 8. Oscillations occurred simultaneously in the left and right motor cortex and could become synchronized with negligible phase shifts when the monkey performed bimanual manipulations. However, synchronization occurred as often and as strongly for unimanual as for bimanual manipulations. 9. These results indicate that episodes of 20- to 40-Hz oscillations occur often and become synchronized over a large cortical area during exploratory forelimb movements. However, they have no reliable relation to particular components of the movement and therefore seem unlikely to be involved directly in movement execution; instead, they may represent a neural correlate of attention during demanding sensorimotor behaviors.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Locomotion is also associated with a simultaneous increase in 30–80 Hz gamma band activity.”
From Waking state: rapid variations modulate neural and behavioral responses (2015) · cites this paper as Murthy and Fetz, 1996
Citations
Cited by
Sorted by citations
Neuronal Synchrony: A Versatile Code for the Definition of Relations?
Singer, W. (1999) · Neuron · doi:10.1016/s0896-6273(00)80821-1 · Cited by 2,581
“In the motor cortex of primates oscillatory modulation of activity in the g frequency range and synchronization of responses both within and across hemispheres were observed in association with self-paced grasping movements or visually guided reaching tasks (Murthy and Fetz, 1996a,b).”
Neural synchrony in brain disorders: Relevance for cognitive dysfunctions and pathophysiology
Uhlhaas, P. J., & Singer, W. (2006) · Neuron · doi:10.1016/j.neuron.2006.09.020 · Cited by 2,194
Neurophysiological and Computational Principles of Cortical Rhythms in Cognition
Wang, X.-J. (2010) · Physiological Reviews · doi:10.1152/physrev.00035.2008 · Cited by 1,939
Correlated neuronal activity and the flow of neural information
Salinas, E., & Sejnowski, T. J. (2001) · Nature Reviews Neuroscience · doi:10.1038/35086012 · Cited by 1,333
Brovelli, A., Ding, M., Ledberg, A., Chen, Y., Nakamura, R., & Bressler, S. L. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308538101 · Cited by 1,073
Temporal structure in neuronal activity during working memory in macaque parietal cortex
Pesaran, B., Pezaris, J. S., Sahani, M., Mitra, P. P., & Andersen, R. A. (2002) · Nature Neuroscience · doi:10.1038/nn890 · Cited by 1,071
“…somatosensory and motor areas reports temporal structure in activity during a period before action (Sanes and Donoghue, 1993; Bressler et al., 1993; Murthy and Fetz, 1996a; Murthy and Fetz, 1996b; Roelfsema et al., 1997) and electroencephalography (EEG) studies in humans report sustained…”
BackgroundTransfer entropy—a model-free measure of effective connectivity for the neurosciences
Vicente, R., Wibral, M., Lindner, M., & Pipa, G. (2010) · Journal of Computational Neuroscience · doi:10.1007/s10827-010-0262-3 · Cited by 1,009
“Coherent activity in the beta band has also been demonstrated between bilateral motor cortices (Mima et al. 2000; Murthy and Fetz 1996).”
BackgroundWaking state: rapid variations modulate neural and behavioral responses
McGinley, M. J., Vinck, M., Reimer, J., Batista-Brito, R., Zagha, E., Cadwell, C. R., Tolias, A. S., Cardin, J. A., & McCormick, D. A. (2015) · Neuron · doi:10.1016/j.neuron.2015.09.012 · Cited by 801
“These striking effects are consistent with those previously reported to occur in the transition from quiet rest to exploration in freely moving animals (reviewed in (Buzsaki, 2006; Murthy and Fetz, 1996; Vanderwolf et al., 1975)).”
Scaling Brain Size, Keeping Timing: Evolutionary Preservation of Brain Rhythms
Buzsáki, G., Logothetis, N., & Singer, W. (2013) · Neuron · doi:10.1016/j.neuron.2013.10.002 · Cited by 886
“An important evolutionary strategy is the myelination of axons and saltatory conduction; the speed of conduction Neuron 80, October 30, 2013 ª2013 Elsevier Inc. 755 Neuron”
Corticothalamic resonance, states of vigilance and mentation
Steriade, M. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00353-5 · Cited by 836
The ups and downs of beta oscillations in sensorimotor cortex
Kilavik, B. E., Zaepffel, M., Brovelli, A., MacKay, W. A., & Riehle, A. (2012) · Experimental Neurology · doi:10.1016/j.expneurol.2012.09.014 · Cited by 854
“Beta oscillations are no exception and they can synchronize over large networks, spanning multiple cortical (Brovelli et al., 2004; Murthy and Fetz, 1992, 1996; Roelfsema et al., 1997) and sub-cortical (Courtemanche and Lamarre, 2005; Courtemanche et al., 2003) areas.”
Intrinsic Fluctuations within Cortical Systems Account for Intertrial Variability in Human Behavior
Fox, M., Snyder, A. Z., Vincent, J. L., & Raichle, M. E. (2007) · Neuron · doi:10.1016/j.neuron.2007.08.023 · Cited by 773
“Coherence has been observed across broad regions of cortex, between cortical hemispheres, and with muscle EMG activity (Baker et al., 1999; Murthy and Fetz, 1996; Salenius and Hari, 2003).”
BackgroundThe thalamic matrix and thalamocortical synchrony
Jones, E. G. (2001) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01922-6 · Cited by 688
Very Slow Activity Fluctuations in Monkey Visual Cortex: Implications for Functional Brain Imaging
Leopold, D. A. (2003) · Cerebral Cortex · doi:10.1093/cercor/13.4.422 · Cited by 675
Dependence of subthalamic nucleus oscillations on movement and dopamine in Parkinson’s disease
Levy, R., Ashby, P., Hutchison, W. D., Lang, A. E., Lozano, A. M., & Dostrovsky, J. O. (2002) · Brain · doi:10.1093/brain/awf128 · Cited by 682
Coherent oscillations in monkey motor cortex and hand muscle EMG show task‐dependent modulation
Baker, S. N., Olivier, E., & LEMON, R. N. (1997) · The Journal of Physiology · doi:10.1111/j.1469-7793.1997.225bo.x · Cited by 668
Shadlen, M. N., & Movshon, J. A. (1999) · Neuron · doi:10.1016/s0896-6273(00)80822-3 · Cited by 606
Constraints on Somatotopic Organization in the Primary Motor Cortex
Schieber, M. H. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.86.5.2125 · Cited by 595
“…interactions within M1, however, comes from studies of local field potential (LFP) oscillations, which occur synchronously over regions of the M1 upper extremity representation extending 14 mm mediolaterally along the central sulcus of monkeys (Donoghue et al. 1998; Murthy and Fetz 1992, 1996a).”
BackgroundMechanisms of deep brain stimulation
Herrington, T. M., Cheng, J. J., & Eskandar, E. N. (2016) · Journal of Neurophysiology · doi:10.1152/jn.00281.2015 · Cited by 551
The Temporal Correlation Hypothesis of Visual Feature Integration
Gray, C. M. (1999) · Neuron · doi:10.1016/s0896-6273(00)80820-x · Cited by 541
Donoghue, J. P., Sanes, J. N., Hatsopoulos, N. G., & Gaál, G. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.79.1.159 · Cited by 538
“…of single cellswith data from visual cortex that suggest a close link between stimulus-driven discharge and LFP oscillations at the same are mixed with aperiodic spiking (Murthy and Fetz 1996b). site (Eckhorn et al. 1988, 1993; Gray and Singer 1989; Gray et al. 1989; Kreiter and Singer 1992).”
BackgroundInfluentialImpact of Network Activities on Neuronal Properties in Corticothalamic Systems
Steriade, M. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.86.1.1 · Cited by 530
Simeral, J. D., Kim, S.-P., Black, M. J., Donoghue, J. P., & Hochberg, L. R. (2011) · Journal of Neural Engineering · doi:10.1088/1741-2560/8/2/025027 · Cited by 496
“Our results are consistent with a number of studies in intact monkeys showing delay period beta activity and subsequent suppression just as movement-related spiking appears at the same site in MI (Sanes and Donoghue 1993, Murthy and Fetz 1996, Donoghue et al 1998).”
von der Malsburg, C. (1999) · Neuron · doi:10.1016/s0896-6273(00)80825-9 · Cited by 501
Propagating waves mediate information transfer in the motor cortex
Rubino, D., Robbins, K. A., & Hatsopoulos, N. G. (2006) · Nature Neuroscience · doi:10.1038/nn1802 · Cited by 508
Murthy, V. N., & Fetz, E. E. (1996) · Journal of Neurophysiology · doi:10.1152/jn.1996.76.6.3968 · Cited by 470
Self-citationThe modulatory effect of adaptive deep brain stimulation on beta bursts in Parkinson’s disease
Tinkhauser, G., Pogosyan, A. H., Little, S. J., Beudel, M., Herz, D. M., Tan, H., & Brown, P. (2017) · Brain · doi:10.1093/brain/awx010 · Cited by 456
On the human sensorimotor-cortex beta rhythm: Sources and modeling
Jensen, O. B., Goel, P., Kopell, N., Pohja, M., Hari, R., & Ermentrout, B. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.02.008 · Cited by 468
“Using intracranial recordings, beta oscillations have also been observed in the motor cortex of monkeys (Baker et al., 1997; Jackson et al., 2002; Murthy and Fetz, 1996; Sanes and Donoghue, 1993).”
BackgroundSynchronous Membrane Potential Fluctuations in Neurons of the Cat Visual Cortex
Lampl, I., Reichova, I., & Ferster, D. (1999) · Neuron · doi:10.1016/s0896-6273(00)81096-x · Cited by 435
Inference of hand movements from local field potentials in monkey motor cortex
Mehring, C., Rickert, J., Vaadia, E., de Oliveira, S. C., Aertsen, A., & Rotter, S. (2003) · Nature Neuroscience · doi:10.1038/nn1158 · Cited by 435
Steriade, M. (1997) · Cerebral Cortex · doi:10.1093/cercor/7.6.583 · Cited by 429
“The view that fast oscillations are implicated in brain attentive processes, either focused or associated with more diffuse arousal, rather than playing a role in sensorimotor binding, is supported by experiments on awake monkeys (Murthy and Fetz, 1997a,b).”
ResultThe role of synchrony and oscillations in the motor output
Baker, S. N., Kilner, J. M., Pinches, E. M., & Lemon, R. (1999) · Experimental Brain Research · doi:10.1007/s002210050825 · Cited by 419
Human Cortical Muscle Coherence Is Directly Related to Specific Motor Parameters
Kilner, J. M., Baker, S. N., Salenius, S., Hari, R., & Lemon, R. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-23-08838.2000 · Cited by 419
“In monkey motor cortex, oscillatory 15–30 Hz activity has been observed in single cells and local field potentials (Murthy and Fetz, 1992, 1996; Baker et al., 1997; Donoghue et al., 1998; Lebedev and Wise, 2000).”
BackgroundBeta burst dynamics in Parkinson’s disease OFF and ON dopaminergic medication
Tinkhauser, G., Pogosyan, A. H., Tan, H., Herz, D. M., Kühn, A. A., & Brown, P. (2017) · Brain · doi:10.1093/brain/awx252 · Cited by 410
“Such a conclusion is supported by studies conducted in healthy non-human primates, which describe beta bursts in the motor network as rather short events, lasting for a few cycles only (Murthy and Fetz, 1992, 1996; Feingold et al., 2015).”
BackgroundResultCortical Correlate of the Piper Rhythm in Humans
Brown, P., Salenius, S., Rothwell, J. C., & Hari, R. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.80.6.2911 · Cited by 405
Information Processing in the Mammalian Olfactory System
Lledo, P., Gheusi, G., & Vincent, J. (2004) · Physiological Reviews · doi:10.1152/physrev.00008.2004 · Cited by 409
EEG–EMG, MEG–EMG and EMG–EMG frequency analysis: physiological principles and clinical applications
Grosse, P., Cassidy, M. J., & Brown, P. (2002) · Clinical Neurophysiology · doi:10.1016/s1388-2457(02)00223-7 · Cited by 393
“However, it was not until the early 1990s that the first evidence emerged supporting a central origin for motor unit synchronisation in humans (McLachlan and Leung, 1991; Farmer et al., 1993) and other primates (Murthy and Fetz, 1992, 1996a,b; Sanes and Donoghue, 1993).”
BackgroundTemporal binding, binocular rivalry, and consciousness
Engel, A. K., Fries, P., König, P., Brecht, M., & Singer, W. (1999) · Consciousness and Cognition · doi:10.1006/ccog.1999.0389 · Cited by 379
“Similar conclusions are suggested by recent studies in monkeys, where synchronization between sensory and motor cortical areas has also been reported (Murthy & Fetz, 1992, 1996a,b).”
ResultCorticomuscular Coherence: A Review
Mima, T., & Hallett, M. (1999) · Journal of Clinical Neurophysiology · doi:10.1097/00004691-199911000-00002 · Cited by 389
Halliday, D. M., Conway, B. A., Farmer, S. F., & Rosenberg, J. R. (1998) · Neuroscience Letters · doi:10.1016/s0304-3940(97)00964-6 · Cited by 386
“In primates, rhythmic correlations between cortical LFPs and EMG have been observed [1,7], which are restricted to periods of maintained contraction [1].”
BackgroundResultInfluentialBeta-Band Activity during Motor Planning Reflects Response Uncertainty
Tzagarakis, C., Ince, N. F., Leuthold, A. C., & Pellizzer, G. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.6026-09.2010 · Cited by 406
“Accordingly, even though the relation between motor cortical oscillatory activity and the spiking activity of single neurons can be complex (Murthy and Fetz, 1996; Donoghue et al., 1998), it was found that there is a strong negative correlation between pyramidal neurons spiking rate and beta-band…”
BackgroundFeingold, J., Gibson, D. J., DePasquale, B., & Graybiel, A. M. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1517629112 · Cited by 370
“Maintenance of the status quo (33), error evaluation and motor adaptation (30, 31), and task difficulty (12, 13) are among the interpretations given to bouts of heightened beta-band activity in normal subjects.”
BackgroundSpatial spectra of scalp EEG and EMG from awake humans
Freeman, W., Holmes, M., Burke, B. C., & Vanhatalo, S. (2003) · Clinical Neurophysiology · doi:10.1016/s1388-2457(03)00045-2 · Cited by 379
“In prior animal studies the narrow-band oscillations at or near 40 Hz, when present prior to action, tended to disappear when the animals become active in a behavioral task (Sanes and Donoghue, 1993; Oram et al., 1996; Murthy and Fetz, 1996; Kay and Freeman, 1998).”
BackgroundSYNCHRONOUS ACTIVITY IN THE VISUAL SYSTEM
Usrey, W. M., & Reid, R. C. (1999) · Annual Review of Physiology · doi:10.1146/annurev.physiol.61.1.435 · Cited by 369
The Role of Neural Mechanisms of Attention in Solving the Binding Problem
Reynolds, J. H., & Desimone, R. (1999) · Neuron · doi:10.1016/s0896-6273(00)80819-3 · Cited by 370
Cortical drives to human muscle: the Piper and related rhythms
Brown, P. (2000) · Progress in Neurobiology · doi:10.1016/s0301-0082(99)00029-5 · Cited by 357
Cellular mechanisms of neuronal population oscillations in the hippocampus in vitro
Traub, R. D., Bibbig, A., LeBeau, F. E. N., Buhl, E. H., & Whittington, M. A. (2004) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.27.070203.144303 · Cited by 358
“…system (Laurent & Davidowitz 1994, Freeman 1972), in sensory and perceptual binding (Gray et al. 1989, Miltner et al. 1999, Rodriguez et al. 1999, Roelfsema et al. 1994, Singer & Gray 1995), in motor programming (Murthy & Fetz 1996), in associative learning (Buzsáki 2002, Larson & ∗Deceased.”
BackgroundRapid feature selective neuronal synchronization through correlated latency shifting
Fries, P., Neuenschwander, S., Engel, A. K., Goebel, R., & Singer, W. (2001) · Nature Neuroscience · doi:10.1038/84032 · Cited by 344
Thalamic circuitry and thalamocortical synchrony
Jones, E. G. (2002) · Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rstb.2002.1168 · Cited by 340
“…binding process by providing a basis for unifying activity in the somatosensory and motor cortex during movement performance (Ribary et al. 1991; Murthy & Fetz 1992, 1996a,b; Sanes & Donoghue 1993), and in parietal areas engaged in perception with that in frontal areas engaged in planning…”
BackgroundBuhl, E. H., Tamás, G., & Fisahn, A. (1998) · The Journal of Physiology · doi:10.1111/j.1469-7793.1998.117by.x · Cited by 337
“Likewise, the dramatic phase-shift at the lower border of layer 4, occurring both in vitro and in vivo (Murthy & Fetz, 1996), is consequently also a phenomenon arising within the isolated cortical network.”
BackgroundDehaene, S., & Changeux, J.-P. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0030141 · Cited by 329
“Overall, our simulations, although obviously very simplified, are not incompatible with experimental observations in awake cats, monkeys, and humans, which indicates that oscillations do occur in awake animals and humans, particularly under conditions of focused, effortful processing, and are typically more prominent…”
ResultRoskies, A. L. (1999) · Neuron · doi:10.1016/s0896-6273(00)80817-x · Cited by 347
Self-paced movements induce high-frequency gamma oscillations in primary motor cortex
Cheyne, D. O., Bells, S., Ferrari, P., Gaetz, W. C., & Bostan, A. C. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.04.178 · Cited by 326
“In recent years, there has been a growing interest in the role of 42 neural oscillations in motor control (Baker et al., 1999; MacKay, 43 1997; Murthy and Fetz, 1996).”
BackgroundKilner, J. M., Baker, S. N., Salenius, S., Jousmäki, V., Hari, R., & Lemon, R. (1999) · The Journal of Physiology · doi:10.1111/j.1469-7793.1999.0559v.x · Cited by 327
Beta activity: a carrier for visual attention
Wróbel, A. (2000) · Acta Neurobiologiae Experimentalis · doi:10.55782/ane-2000-1344 · Cited by 324
MEG studies of sensorimotor rhythms: A review
Cheyne, D. O. (2012) · Experimental Neurology · doi:10.1016/j.expneurol.2012.08.030 · Cited by 321
“, 2011; Murthy and Fetz, 1992; Sanes and Donoghue, 1993) and to be only loosely time-locked to specific phases of motor output, and therefore indicative of non-specific aspects of sensorimotor integration (Murthy and Fetz, 1996).”
Solutions to the Binding Problem
Treisman, A. (1999) · Neuron · doi:10.1016/s0896-6273(00)80826-0 · Cited by 327
Object Selectivity of Local Field Potentials and Spikes in the Macaque Inferior Temporal Cortex
Kreiman, G., Hung, C. P., Kraskov, A., Quiroga, R. Q., Poggio, T., & DiCarlo, J. J. (2006) · Neuron · doi:10.1016/j.neuron.2005.12.019 · Cited by 309
“For example, Murthy and Fetz reported that sites separated by up to 14 mm in precentral cortex showed significant correlation in the LFP activity in the 20–40 Hz band (Murthy and Fetz, 1996).”
BackgroundKristeva, R., Patino, L., & Omlor, W. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.03.025 · Cited by 309
“, 2000), and with the attention paid (Murthy and Fetz, 1996; Kristeva-Feige et al., 2002).”
BackgroundAltered excitatory-inhibitory balance in the NMDA-hypofunction model of schizophrenia
Kehrer, C. (2008) · Frontiers in Molecular Neuroscience · doi:10.3389/neuro.02.006.2008 · Cited by 287
“Network oscillations are thought to be important in sensory processing (Averbeck and Lee, 2004; Laurent and Davidowitz, 1994), motor programming (Murthy and Fetz, 1996) associative learning (Buzsáki, 2002) and attention (Jensen et al., 2007).”
BackgroundFast and Slow Oscillations in Human Primary Motor Cortex Predict Oncoming Behaviorally Relevant Cues
Saleh, M., Reimer, J., Penn, R., Ojakangas, C. L., & Hatsopoulos, N. G. (2010) · Neuron · doi:10.1016/j.neuron.2010.02.001 · Cited by 281
“…a stable posture by inhibiting movement (Baker et al., 1999; Kü hn et al., 2008b), and the second that they are related to some aspect of movement planning or attention (Donoghue et al., 1998; Murthy and Fetz, 1992, 1996; Roux et al., 2006; Sanes and Donoghue, 1993; Schwartz et al., 2005).”
BackgroundCourtemanche, R., Fujii, N., & Graybiel, A. M. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-37-11741.2003 · Cited by 339
“LFPs are not simply a reflection of neuronal spiking, but synchronization of spike timing to these oscillations occurs for some neurons in the sensorimotor and frontal cortex (Lebedev and Nelson, 1995; Murthy and Fetz, 1996b; Baker et al., 1999).”
BackgroundLebedev, M., Carmena, J. M., O’Doherty, J. E., Zacksenhouse, M., Henriquez, C. S., Príncipe, J. C., & Nicolelis, M. A. L. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.4088-04.2005 · Cited by 291
“Interestingly , epochs of high attention to motor performance ( and increased attention is very likely needed for successful learn - ing to control a BMI ) have been found to be associated with increases of synchrony between neurons ( Murthy and Fetz , 1992 , 1996a , b ; Riehle et al .”
BackgroundElectroencephalographic measurement of motor cortex control of muscle activity in humans
Mima, T., Steger, J., Schulman, A. E., Gerloff, C. P., & Hallett, M. (2000) · Clinical Neurophysiology · doi:10.1016/s1388-2457(99)00229-1 · Cited by 289
Rhythmicity, synchronization and binding in human and primate motor systems
Farmer, S. F. (1998) · The Journal of Physiology · doi:10.1111/j.1469-7793.1998.003bo.x · Cited by 272
Compte, A., Constantinidis, C., Tegner, J. N., Raghavachari, S., Chafee, M. V., Goldman, P. S., & Wang, X. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00949.2002 · Cited by 266
“We thank M. N. Franowicz who participated in some of the recordings, Y.-H. Liu for contribution to the initial phase of data analysis, and B. J. Pesaran for helpful comments on the manuscript.”
BackgroundMethodSteriade, M., Timofeev, I., Dürmüller, N., & Grenier, F. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.79.1.483 · Cited by 254
Human motor cortical beta bursts relate to movement planning and response errors
Little, S. J., Bonaiuto, J. J., Barnes, G. R., & Bestmann, S. (2019) · PLoS Biology · doi:10.1371/journal.pbio.3000479 · Cited by 244
Neuper, C., & Pfurtscheller, G. (2001) · Clinical Neurophysiology · doi:10.1016/s1388-2457(01)00661-7 · Cited by 250
Decoding natural grasp types from human ECoG
Pistohl, T., Schulze‐Bonhage, A., Aertsen, A., Mehring, C., & Ball, T. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.06.084 · Cited by 253
Functional Properties of Electrical Synapses Between Inhibitory Interneurons of Neocortical Layer 4
Gibson, J. R., Beierlein, M., & Connors, B. W. (2005) · Journal of Neurophysiology · doi:10.1152/jn.00520.2004 · Cited by 242
High-frequency brain activity: Its possible role in attention, perception and language processing
Friedemann Pulvermüller, A., Birbaumer, N., Lutzenberger, W., & Mohr, B. (1997) · Progress in Neurobiology · doi:10.1016/s0301-0082(97)00023-3 · Cited by 246
Kristeva-Feige, R., Fritsch, C., Timmer, J., et al. (2002) · Clinical Neurophysiology · doi:10.1016/s1388-2457(01)00722-2 · Cited by 244
Neural synchrony within the motor system: what have we learned so far?
van Wijk, B. C. M., Beek, P. J., & Daffertshofer, A. (2012) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2012.00252 · Cited by 263
“Murthy and Fetz (1996a) reported synchronous oscillations between sites within motor areas, between pre- and post-central sites and occasionally also between bilateral motor areas.”
BackgroundRole of the temporal domain for response selection and perceptual binding
Engel, A. (1997) · Cerebral Cortex · doi:10.1093/cercor/7.6.571 · Cited by 237
“Similar evidence is available for the motor system, where neural synchronization in the gamma frequency range has been discovered in cats (Steriade et al., 1996), monkeys (Murthy and Fetz, 1992, 1996a,b; Sanes and Donoghue, 1993) and humans (Kristeva-Feige et al., 1993).”
BackgroundInfluentialIonic Mechanisms Underlying Repetitive High-Frequency Burst Firing in Supragranular Cortical Neurons
Brumberg, J. C., Nowak, L. G., & McCormick, D. A. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-13-04829.2000 · Cited by 234
Multiple Features of Motor-Unit Activity Influence Force Fluctuations During Isometric Contractions
Taylor, A. M., Christou, E. A., & Enoka, R. M. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00056.2003 · Cited by 233
Neural mechanisms of mental fatigue
Ishii, A., Tanaka, M., & Watanabe, Y. (2014) · Reviews in the Neurosciences · doi:10.1515/revneuro-2014-0028 · Cited by 260
The role of GABAergic modulation in motor function related neuronal network activity
Hall, S. D., Stanford, I. M., Yamawaki, N., McAllister, C. J., Rönnqvist, K. C., Woodhall, G. L., & Furlong, P. L. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.02.025 · Cited by 229
“At rest, the primary motor cortex (M1) exhibits ongoing neuronal network oscillations in the beta (15-30Hz) frequency range (Baker et al., 1997; Murthy and Fetz, 1996).”
Baker, S. N., Pinches, E. M., & LEMON, R. N. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00832.2002 · Cited by 214
“Murthy and Fetz (1996b) showed explicitly an increase in pairwise neuronal synchrony during epochs of field potential oscillatory activity.”
BackgroundMethodResultInfluentialGoldberg, J. A., Rokni, U., Boraud, T., Vaadia, E., & Bergman, H. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.4848-03.2004 · Cited by 211
“…that were separated by up to a few millimeters in either cortex or the BG, indicating that the LFPs constitute a signal common to large volumes of tissue (Eckhorn and Obermueller, 1993; Sanes and Donoghue, 1993; Murthy and Fetz, 1996b; Contreras et al., 1997; Bullock, 1999; Destexhe et al., 1999).”
BackgroundResultInfluentialMovement-related change of electrocorticographic activity in human supplementary motor area proper
Ohara, S. (2000) · Brain · doi:10.1093/brain/123.6.1203 · Cited by 215
Gaetz, W. C., & Cheyne, D. O. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.10.009 · Cited by 206
Synchronous oscillatory activity in sensory systems: new vistas on mechanisms
Ritz, R., & B, T. J. S. A. (1997) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(97)80034-7 · Cited by 202
Accurate decoding of reaching movements from field potentials in the absence of spikes
Flint, R. D., Lindberg, E. W., Jordan, L. R., Miller, L. E., & Slutzky, M. W. (2012) · Journal of Neural Engineering · doi:10.1088/1741-2560/9/4/046006 · Cited by 199
“1741-2560/12/046006+13$33.00 1 © 2012 IOP Publishing Ltd Printed in the UK & the USA”
InfluentialSynchronized neuronal oscillations and their role in motor processes
MacKay, W. A. (1997) · Trends in Cognitive Sciences · doi:10.1016/s1364-6613(97)01059-0 · Cited by 202
Coding and transmission of information by neural ensembles
Averbeck, B. B., & Lee, D. (2004) · Trends in Neurosciences · doi:10.1016/j.tins.2004.02.006 · Cited by 192
Baker, S. N., Spinks, R. L., Jackson, A., & Lemon, R. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.85.2.869 · Cited by 198
The Psychophysical Evidence for a Binding Problem in Human Vision
Wolfe, J. M., & Cave, K. R. (1999) · Neuron · doi:10.1016/s0896-6273(00)80818-1 · Cited by 197
Are Cortical Models Really Bound by the “Binding Problem”?
Riesenhuber, M., & Poggio, T. (1999) · Neuron · doi:10.1016/s0896-6273(00)80824-7 · Cited by 194
Brain Oscillations in Sport: Toward EEG Biomarkers of Performance
Cheron, G. A., Petit, G., Chéron, J., Leroy, A., Cebolla, A. M., Cevallos, C., Petieau, M., Hoellinger, T., Zarka, D., Clarinval, A.-M., et al. (2016) · Frontiers in Psychology · doi:10.3389/fpsyg.2016.00246 · Cited by 215
Neurophysiologic correlates of fMRI in human motor cortex
Hermes, D., Miller, K. J., Vansteensel, M. J., Aarnoutse, E. J., Leijten, F. S. S., & Ramsey, N. F. (2011) · Human Brain Mapping · doi:10.1002/hbm.21314 · Cited by 186
Manipulation of peripheral neural feedback loops alters human corticomuscular coherence
Riddle, C. N., & Baker, S. N. (2005) · The Journal of Physiology · doi:10.1113/jphysiol.2005.089607 · Cited by 185
“…much recent interest in motor cortical oscillations, where rhythms at ∼10 Hz and ∼15–30 Hz occur in both animals and humans (Salmelin & Hari, 1994; Murthy & Fetz, 1996; Stancak & Pfurtscheller, 1996; Baker et al. 1997; Salenius et al. 1997; Donoghue et al. 1998; Halliday et al. 1998; Brown et…”
BackgroundSelective inhibition of movement
Coxon, J. P., Stinear, C. M., & Byblow, W. D. (2007) · Journal of Neurophysiology · doi:10.1152/jn.01284.2006 · Cited by 173
The effect of diazepam on motor cortical oscillations and corticomuscular coherence studied in man
Baker, M. R., & Baker, S. N. (2003) · The Journal of Physiology · doi:10.1113/jphysiol.2002.029553 · Cited by 180
“Oscillations around 20–30 Hz (‘beta’ band) arise from the primary motor cortex (Murthy & Fetz, 1996; Baker et al. 1997; Donoghue et al. 1998; Kilner et al. 1999).”
BackgroundIncreased gamma-range activity in human sensorimotor cortex during performance of visuomotor tasks
Aoki, F., Fetz, E. E., Shupe, L., Lettich, E., & Ojemann, G. A. (1999) · Clinical Neurophysiology · doi:10.1016/s1388-2457(98)00064-9 · Cited by 182
“The cortical extent of the synchronous activity was more restricted in these human recordings than previously found in monkey sensorimotor cortex (Bressler et al., 1993; Murthy and Fetz, 1992; Murthy and Fetz, 1996a; Sanes and Donoghue, 1993).”
InfluentialSelf-citationIvry, R. B. (2000) · Human Brain Mapping · doi:10.1002/(sici)1097-0193(200003)9:3 · Cited by 73
Lau, D., de Miera, E. V., Contreras, D., Ozaita, A., Harvey, M., Chow, A., Noebels, J. L., Paylor, R. E., Morgan, J. I., Leonard, C. S., et al. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-24-09071.2000 · Cited by 175
“As shown in Figure 11 A , wild-type mice ( n 5 21) showed the characteristic slow rhythm observed during natural slow-wave sleep and during ketamine–xylazine anesthesia in other species (Steriade et al., 1993a; Contreras and Steriade, 1995).”
Changes in corticospinal drive to spinal motoneurones following visuo‐motor skill learning in humans
Pérez, M. A., Lundbye‐Jensen, J., & Nielsen, J. B. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.105361 · Cited by 174
“…corticospinal input to spinal motoneurones have been shown to take place during a motor task that requires a high degree of attention and precision (Murthy & Fetz, 1996; Schmied et al. 2000; Kilner et al. 2002; Kristeva-Feige et al. 2002), but, so far, the interaction between corticospinal inputs…”
BackgroundThe response of cat visual cortex to flicker stimuli of variable frequency
Rager, G. H., & Singer, W. (1998) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1998.00197.x · Cited by 170
Metadata
- Authors
- Murthy, V. N., & Fetz, E. E.
- Affiliations
- University of Washington (US)
- Venue
- Journal of Neurophysiology
- Publisher
- American Physiological Society
- Published
- 1996-12-01
- Volume
- 76
- Issue
- 6
- Pages
- 3949-3967
- ISSN
- 0022-3077 (ISSN-L)
- 1522-1598
- OpenAlex
- W1787747564
- Cited by
- 544
- References
- 0
- Citations by year
- 2026: 4 · 2025: 12 · 2024: 11 · 2023: 11 · 2022: 13 · 2021: 13 · 2020: 13 · 2019: 11 · 2018: 16 · 2017: 16 · 2016: 16 · 2015: 16 · 2014: 25 · 2013: 17 · 2012: 18
- FWCI
- 14.02
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Neurophysiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Neurological Disorders and Stroke (NS12542)
- National Center for Research Resources (RR00166, P51RR000166)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- sensorimotor cortex, local field potentials, cortical oscillations, neuronal synchronization, precentral cortex, inter-site correlation, exploratory behavior, somatosensory feedback, arm movement, monkey behavior, unit activity
- MeSH terms
- Animals, Electromyography, Evoked Potentials, Somatosensory, Exploratory Behavior, Feedback, Hand, Functional Laterality, Macaca mulatta, Macaca nemestrina, Movement, Neurons, Periodicity, Somatosensory Cortex, Time Factors, Evoked Potentials, Motor
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
