The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Mammalian G Proteins and Their Cell Type Specific Functions
Abstract
Heterotrimeric G proteins are key players in transmembrane signaling by coupling a huge variety of receptors to channel proteins, enzymes, and other effector molecules. Multiple subforms of G proteins together with receptors, effectors, and various regulatory proteins represent the components of a highly versatile signal transduction system. G protein-mediated signaling is employed by virtually all cells in the mammalian organism and is centrally involved in diverse physiological functions such as perception of sensory information, modulation of synaptic transmission, hormone release and actions, regulation of cell contraction and migration, or cell growth and differentiation. In this review, some of the functions of heterotrimeric G proteins in defined cells and tissues are described.
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Cited by
Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling
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Neural Control of Renal Function*
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Activation of Platelet Function Through G Protein–Coupled Receptors
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Self-citationSignaling pathways controlling skeletal muscle mass
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Regulation, signaling, and physiological functions of G-Proteins
Syrovatkina, V., Alegre, K. O., Dey, R., & Huang, X.-Y. (2016) · Journal of Molecular Biology · doi:10.1016/j.jmb.2016.08.002 · Cited by 498
Metadata
- Authors
- Wettschureck, N., & Offermanns, S.
- Venue
- Physiological Reviews
- Publisher
- American Physiological Society
- Published
- 2005-10
- Volume
- 85
- Issue
- 4
- Pages
- 1159-1204
- ISSN
- 0031-9333 (ISSN-L)
- 1522-1210
- OpenAlex
- W2005614924
- Cited by
- 1,166
- References
- 23
- FWCI
- 2.09
- Type
- journal article
- Language
- en
- Open access
- closed
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