Cited by 238Immune Response and InflammationMicroRNA in disease regulationInflammasome and immune disorders

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MicroRNAs: New Regulators of Toll-Like Receptor Signalling Pathways

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He, Xiaobing, Jing, Zhizhong, Cheng, Guofeng·2014·BioMed Research International

DOI 10.1155/2014/945169PMC PMC3977468

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Abstract

Toll-like receptors (TLRs), a critical family of pattern recognition receptors (PRRs), are responsible for the innate immune responses via signalling pathways to provide effective host defence against pathogen infections. However, TLR-signalling pathways are also likely to stringently regulate tissue maintenance and homeostasis by elaborate modulatory mechanisms. MicroRNAs (miRNAs) have emerged as key regulators and as an essential part of the networks involved in regulating TLR-signalling pathways. In this review, we highlight our understanding of the regulation of miRNA expression profiles by TLR-signalling pathways and the regulation of TLR-signalling pathways by miRNAs. We focus on the roles of miRNAs in regulating TLR-signalling pathways by targeting multiple molecules, including TLRs themselves, their associated signalling proteins and regulatory molecules, and transcription factors and functional cytokines induced by them, at multiple levels.

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MicroRNAs: Target Recognition and Regulatory Functions
Bartel, D. P. (2009) · Cell · doi:10.1016/j.cell.2009.01.002 · Cited by 20,068
Untitled work
(2008) · doi:10.1038/nrg2290 · Cited by 5,199
NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
Taganov, K. D., Boldin, M. P., Chang, K.-J., & Baltimore, D. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0605298103 · Cited by 4,317
Cellular and Molecular Immunology
Abbas, A. K., Lichtman, A. H., & Pillai, S. S. (1994) · Cited by 3,571
Regulation of mRNA Translation and Stability by microRNAs
Fabian, M. R., Sonenberg, N., & Filipowicz, W. (2010) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060308-103103 · Cited by 3,214
MicroRNA-155 is induced during the macrophage inflammatory response
O'Connell, R. M., Taganov, K. D., Boldin, M. P., Cheng, G., & Baltimore, D. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0610731104 · Cited by 1,866
Self-citation
Identification of Virus-Encoded MicroRNAs
Pfeffer, S., Zavolan, M., Grässer, F., Chien, M.-C., Russo, J., Ju, J.-Y., John, B., Enright, A., Marks, D., Sander, C., et al. (2004) · Science · doi:10.1126/science.1096781 · Cited by 1,708
Signaling in innate immunity and inflammation
Newton, K., & Dixit, V. M. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a006049 · Cited by 1,513
Regulation of the Germinal Center Response by MicroRNA-155
Thai, T., Calado, D. P., Casola, S. S., Ansel, K. M., Xiao, C., Xue, Y., Murphy, A. J., Frendewey, D. A., Valenzuela, D. M., Kutok, J. L., et al. (2007) · Science · doi:10.1126/science.1141229 · Cited by 1,477
MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response
Fabbri, M., Paone, A., Calore, F., Galli, R., Gaudio, E., Santhanam, R., Lovat, F., Fadda, P., Mao, C., Nuovo, G. J., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1209414109 · Cited by 1,434
Physiological and pathological roles for microRNAs in the immune system
O'Connell, R. M., Rao, D. S., Chaudhuri, A. A., & Baltimore, D. (2010) · Nature Reviews Immunology · doi:10.1038/nri2708 · Cited by 1,378
An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation
Iliopoulos, D., Hirsch, H. A., & Struhl, K. (2009) · Cell · doi:10.1016/j.cell.2009.10.014 · Cited by 1,374
Modulation of miR-155 and miR-125b Levels following Lipopolysaccharide/TNF-α Stimulation and Their Possible Roles in Regulating the Response to Endotoxin Shock
Tili, E., Michaille, J.-J., Cimino, A., Costinean, S., Dumitru, C. D., Adair, B., Fabbri, M., Alder, H., Liu, C. G., Calin, G. A., et al. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.8.5082 · Cited by 1,304
Regulation of progenitor cell proliferation and granulocyte function by microRNA-223
Johnnidis, J. B., Harris, M. H., Wheeler, R. T., Stehling-Sun, S., Lam, M. H., Kirak, O., Brummelkamp, T. R., Fleming, M. D., & Camargo, F. D. (2008) · Nature · doi:10.1038/nature06607 · Cited by 1,208
Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21
Sheedy, F. J., Palsson-McDermott, E., Hennessy, E. J., Martin, C., O'Leary, J. J., Ruan, Q., Johnson, D. S., Chen, Y., & O'Neill, L. A. J. (2010) · Nature Immunology · doi:10.1038/ni.1828 · Cited by 1,005
MicroRNAs: the fine-tuners of Toll-like receptor signalling
O'Neill, L. A. J., Sheedy, F. J., & McCoy, C. E. (2011) · Nature reviews. Immunology · doi:10.1038/nri2957 · Cited by 881
miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice
Boldin, M. P., Taganov, K. D., Rao, D. S., Yang, L., Zhao, J. L., Kalwani, M., Garcia-Flores, Y., Luong, M., Devrekanli, A., Xu, J., et al. (2011) · Journal of Experimental Medicine · doi:10.1084/jem.20101823 · Cited by 861
Involvement of MicroRNA in AU-Rich Element-Mediated mRNA Instability
Jing, Q., Huang, S., Guth, S., Zarubin, T., Motoyama, A. B., Chen, J., Padova, F. D., Lin, S., Gram, H., & Han, J. (2005) · Cell · doi:10.1016/j.cell.2004.12.038 · Cited by 849
microRNA Regulation of Inflammatory Responses
O'Connell, R. M., Rao, D. S., & Baltimore, D. (2012) · Annual Review of Immunology · doi:10.1146/annurev-immunol-020711-075013 · Cited by 843
Inositol phosphatase SHIP1 is a primary target of miR-155
O'Connell, R. M., Chaudhuri, A. A., Rao, D. S., & Baltimore, D. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0902636106 · Cited by 826
An unconventional role for miRNA: let-7 activates toll-like receptor 7 and causes neurodegeneration
Lehmann, S. M., Krüger, C., Park, B., Derkow, K., Rosenberger, K., Baumgart, J., Trimbuch, T., Eom, G., Hinz, M., Kaul, D., et al. (2012) · Nature Neuroscience · doi:10.1038/nn.3113 · Cited by 786
MicroRNAs: Novel Regulators Involved in the Pathogenesis of Psoriasis?
Sonkoly, E., Wei, T., Janson, P. C. J., Sääf, A., Lundeberg, L., Tengvall-Linder, M., Norstedt, G., Alenius, H., Homey, B., Scheynius, A., et al. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000610 · Cited by 754
MicroRNA-146a Feedback Inhibits RIG-I-Dependent Type I IFN Production in Macrophages by Targeting TRAF6, IRAK1, and IRAK2
Hou, J., Wang, P., Lin, L., Liu, X., Ma, F., An, H., Wang, Z., & Cao, X. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0900707 · Cited by 739
The Long and Short of MicroRNA
Yates, L. A., Norbury, C. J., & Gilbert, R. J. C. (2013) · Cell · doi:10.1016/j.cell.2013.04.003 · Cited by 706
Viruses, microRNAs, and Host Interactions
Skalsky, R. L., & Cullen, B. R. (2010) · Annual Review of Microbiology · doi:10.1146/annurev.micro.112408.134243 · Cited by 689
The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-γ
Ma, F., Xu, S., Liu, X., Zhang, Q., Xu, X., Liu, M., Hua, M.-M., Li, N., Yao, H., & Cao, X. (2011) · Nature Immunology · doi:10.1038/ni.2073 · Cited by 659
AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2
Vasudevan, S., & Steitz, J. A. (2007) · Cell · doi:10.1016/j.cell.2007.01.038 · Cited by 656
MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells
Ceppi, M., Pereira, P. M., Dunand-Sauthier, I., Barras, E., Reith, W., Santos, M. A., & Pierre, P. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811073106 · Cited by 631
Suppression of MicroRNA-Silencing Pathway by HIV-1 During Virus Replication
Triboulet, R., Mari, B. P., Lin, Y., Chable-Bessia, C., Bennasser, Y., Lebrigand, K., Cardinaud, B., Maurin, T., Barbry, P., Baillat, V., et al. (2007) · Science · doi:10.1126/science.1136319 · Cited by 627
NF-κB–YY1–miR-29 Regulatory Circuitry in Skeletal Myogenesis and Rhabdomyosarcoma
Wang, H., Garzon, R., Sun, H., Ladner, K. J., Singh, R. K., Dahlman, J. M., Cheng, A. S. L., Hall, B. M., Qualman, S. J., Chandler, D. S., et al. (2008) · Cancer Cell · doi:10.1016/j.ccr.2008.10.006 · Cited by 601
The Kinase Akt1 Controls Macrophage Response to Lipopolysaccharide by Regulating MicroRNAs
Androulidaki, A., Iliopoulos, D., Arranz, A., Doxaki, C., Schworer, S., Zacharioudaki, V., Margioris, A. N., Tsichlis, P. N., & Tsatsanis, C. (2009) · Immunity · doi:10.1016/j.immuni.2009.06.024 · Cited by 581
MicroRNA-21 Is Up-Regulated in Allergic Airway Inflammation and Regulates IL-12p35 Expression
Lu, T. X., Munitz, A., & Rothenberg, M. E. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0803560 · Cited by 580
Identification of miR-145 and miR-146a as mediators of the 5q– syndrome phenotype
Starczynowski, D. T., Kuchenbauer, F., Argiropoulos, B., Sung, S., Morin, R., Muranyi, A., Hirst, M., Hogge, D., Marra, M., Wells, R. A., et al. (2010) · Nature Medicine · doi:10.1038/nm.2054 · Cited by 577
Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals
Bazzoni, F., Rossato, M., Fabbri, M., Gaudiosi, D., Mirolo, M., Mori, L., Tamassia, N., Mantovani, A., Cassatella, M. A., & Locati, M. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0810909106 · Cited by 548 · cited 3×
“For example, miR-9 expression is directly induced by LPS via the TLR4-MyD88-NF-κB-dependent pathway in human monocytes and neutrophils [58].”
BackgroundInfluential
NLRP3 inflammasome activity is negatively controlled by miR-223
Bauernfeind, F., Rieger, A., Schildberg, F. A., Knolle, P. A., Schmid-Burgk, J. L., & Hornung, V. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1201516 · Cited by 544
MicroRNAs in NF- B signaling
Ma, X., Becker Buscaglia, L. E., Barker, J. R., & Li, Y. (2011) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjr007 · Cited by 542
The Transformation Suppressor Pdcd4 Is a Novel Eukaryotic Translation Initiation Factor 4A Binding Protein That Inhibits Translation
Yang, H.-S., Jansen, A. P., Komar, A. A., Zheng, X., Merrick, W. C., Costes, S., Lockett, S. J., Sonenberg, N., & Colburn, N. H. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.1.26-37.2003 · Cited by 494
A Cellular Micro-RNA, let-7i, Regulates Toll-like Receptor 4 Expression and Contributes to Cholangiocyte Immune Responses against Cryptosporidium parvum Infection
Chen, X., Splinter, P. L., O’Hara, S. P., & LaRusso, N. F. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m702633200 · Cited by 490
Newly described pattern recognition receptors team up against intracellular pathogens
Brož, P., & Monack, D. M. (2013) · Nature reviews. Immunology · doi:10.1038/nri3479 · Cited by 481
Cutting Edge: miR-223 and EBV miR-BART15 Regulate the NLRP3 Inflammasome and IL-1β Production
Haneklaus, M., Gerlic, M., Kurowska‐Stolarska, M., Rainey, A., Pich, D., McInnes, I. B., Hammerschmidt, W., O'Neill, L. A. J., & Masters, S. L. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1200312 · Cited by 466
Rapid Changes in MicroRNA-146a Expression Negatively Regulate the IL-1β-Induced Inflammatory Response in Human Lung Alveolar Epithelial Cells
Perry, M. M., Moschos, S. A., Williams, A. E., Shepherd, N. J., Larner-Svensson, H. M., & Lindsay, M. A. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.8.5689 · Cited by 461
miR-21 Gene Expression Triggered by AP-1 Is Sustained through a Double-Negative Feedback Mechanism
Fujita, S., Ito, T., Mizutani, T., Minoguchi, S., Yamamichi, N., Sakurai, K., & Iba, H. (2008) · Journal of Molecular Biology · doi:10.1016/j.jmb.2008.03.015 · Cited by 448
miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses
Liu, G., Friggeri, A., Yang, Y., Park, Y.-J., Tsuruta, Y., & Abraham, E. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0901216106 · Cited by 438
Inducible microRNA-155 Feedback Promotes Type I IFN Signaling in Antiviral Innate Immunity by Targeting Suppressor of Cytokine Signaling 1
Wang, P., Hou, J., Lin, L., Wang, C., Liu, X., Li, D., Ma, F., Wang, Z., & Cao, X. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1000491 · Cited by 431
miR-146a Is Critical for Endotoxin-induced Tolerance
Nahid, M. A., Pauley, K. M., Satoh, M., & Chan, E. K. L. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.056317 · Cited by 423
Dissecting negative regulation of Toll-like receptor signaling
Kondo, T., Kawai, T., & Akira, S. (2012) · Trends in Immunology · doi:10.1016/j.it.2012.05.002 · Cited by 419
Virus-encoded microRNAs
Grundhoff, A. T., & Sullivan, C. S. (2011) · Virology · doi:10.1016/j.virol.2011.01.002 · Cited by 416
Virus-Encoded microRNAs: An Overview and a Look to the Future
Kincaid, R. P., & Sullivan, C. S. (2012) · PLoS Pathogens · doi:10.1371/journal.ppat.1003018 · Cited by 401
Cutting Edge: The Foxp3 Target miR-155 Contributes to the Development of Regulatory T Cells
Kohlhaas, S. L., Garden, O. A., Scudamore, C. L., Turner, M., Okkenhaug, K., & Vigorito, E. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0803162 · Cited by 381
MicroRNA-132 Potentiates Cholinergic Anti-Inflammatory Signaling by Targeting Acetylcholinesterase
Shaked, I., Meerson, A., Wolf, Y., Avni, R., Greenberg, D., Gilboa-Geffen, A., & Soreq, H. (2009) · Immunity · doi:10.1016/j.immuni.2009.09.019 · Cited by 366
MicroRNA-21 Limits In Vivo Immune Response-Mediated Activation of the IL-12/IFN-γ Pathway, Th1 Polarization, and the Severity of Delayed-Type Hypersensitivity
Lu, T. X., Hartner, J. C., Lim, E. J., Fabry, V., Mingler, M. K., Cole, E. T., Orkin, S. H., Aronow, B. J., & Rothenberg, M. E. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1101235 · Cited by 350
MicroRNAs modulate the noncanonical transcription factor NF-κB pathway by regulating expression of the kinase IKKα during macrophage differentiation
Li, T., Morgan, M. J., Choksi, S., Zhang, Y., Kim, Y., & Liu, Z.-G. (2010) · Nature Immunology · doi:10.1038/ni.1918 · Cited by 342
When Signaling Pathways Collide: Positive and Negative Regulation of Toll-like Receptor Signal Transduction
O'Neill, L. A. J. (2008) · Immunity · doi:10.1016/j.immuni.2008.06.004 · Cited by 333
Epstein-Barr Virus Latent Membrane Protein 1 Induces Cellular MicroRNA miR-146a, a Modulator of Lymphocyte Signaling Pathways
Cameron, J. E., Yin, Q., Fewell, C., Lacey, M. R., McBride, J., Wang, X., Lin, Z. N., Schaefer, B. C., & Flemington, E. K. (2007) · Journal of Virology · doi:10.1128/jvi.02136-07 · Cited by 309
MicroRNA in TLR signaling and endotoxin tolerance
Nahid, M. A., Satoh, M., & Chan, E. K. L. (2011) · Cellular and Molecular Immunology · doi:10.1038/cmi.2011.26 · Cited by 299
miR-132 regulates antiviral innate immunity through suppression of the p300 transcriptional co-activator
Lagos, D., Pollara, G., Henderson, S., Gratrix, F., Fabani, M., Milne, R. S. B., Gotch, F., & Boshoff, C. (2010) · Nature Cell Biology · doi:10.1038/ncb2054 · Cited by 296
Src homology 2 domain–containing inositol-5-phosphatase and CCAAT enhancer-binding protein β are targeted by miR-155 in B cells of Eμ-MiR-155 transgenic mice
Costinean, S., Sandhu, S. K., Pedersen, I. M., Tili, E., Trotta, R., Perrotti, D., Ciarlariello, D., Neviani, P., Harb, J. G., Kauffman, L. R., et al. (2009) · Blood · doi:10.1182/blood-2009-05-220814 · Cited by 292
Regulation of IKKβ by miR-199a affects NF-κB activity in ovarian cancer cells
Chen, R. J., Alvero, A. B., Silasi, D., Kelly, M. G., Fest, S., Visintin, I., Leiser, A., Schwartz, P. E., Rutherford, T., & Mor, G. (2008) · Oncogene · doi:10.1038/onc.2008.112 · Cited by 291
Negative regulation of Toll-like receptor 4 signaling by IL-10–dependent microRNA-146b
Curtale, G., Mirolo, M., Renzi, T. A., Rossato, M., Bazzoni, F., & Locati, M. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1219852110 · Cited by 289
Expression profiling in vivo demonstrates rapid changes in lung microRNA levels following lipopolysaccharide-induced inflammation but not in the anti-inflammatory action of glucocorticoids
Moschos, S. A., Williams, A. E., Perry, M. M., Birrell, M. A., Belvisi, M. G., & Lindsay, M. A. (2007) · BMC Genomics · doi:10.1186/1471-2164-8-240 · Cited by 286
MicroRNA-148/152 Impair Innate Response and Antigen Presentation of TLR-Triggered Dendritic Cells by Targeting CaMKIIα
Liu, X.-G., Zhan, Z.-Z., Xu, L., Ma, F., Li, D., Guo, Z.-H., Li, N., & Cao, X.-T. (2010) · Journal of Immunology · doi:10.4049/jimmunol.1001573 · Cited by 286
The interplay between transcription factors and microRNAs in genome‐scale regulatory networks
Martinez, N. J., & Walhout, A. J. M. (2009) · BioEssays · doi:10.1002/bies.200800212 · Cited by 278
Inducible MicroRNA-223 Down-Regulation Promotes TLR-Triggered IL-6 and IL-1β Production in Macrophages by Targeting STAT3
Chen, Q., Wang, H., Liu, Y., Song, Y., Lai, L., Han, Q., Cao, X., & Wang, Q. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042971 · Cited by 275
MiR-146a inhibits oxidized low-density lipoprotein-induced lipid accumulation and inflammatory response via targeting toll-like receptor 4
Yang, K., He, Y. S., Wang, X. Q., Lu, L., Chen, Q., Liu, J., Sun, Z., & Shen, W. F. (2011) · FEBS Letters · doi:10.1016/j.febslet.2011.02.009 · Cited by 261
IL-10 Inhibits miR-155 Induction by Toll-like Receptors
McCoy, C. E., Sheedy, F. J., Qualls, J. E., Doyle, S., Quinn, S. R., Murray, P. J., & O'Neill, L. A. J. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.102111 · Cited by 256
Epstein–Barr virus latent membrane protein 1 trans-activates miR-155 transcription through the NF-κB pathway
Gatto, G., Rossi, A., Rossi, D. P., Kroening, S., Bonatti, S., & Mallardo, M. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn666 · Cited by 254
MicroRNA-466l Upregulates IL-10 Expression in TLR-Triggered Macrophages by Antagonizing RNA-Binding Protein Tristetraprolin-Mediated IL-10 mRNA Degradation
Ma, F., Liu, X., Li, D., Wang, P., Li, N., Lu, L., & Cao, X. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0902308 · Cited by 251
Sp1/NFκB/HDAC/miR-29b Regulatory Network in KIT-Driven Myeloid Leukemia
Liu, S., Wu, L., Pang, J., Santhanam, R., Schwind, S., Wu, Y., Hickey, C. J., Yu, J., Becker, H., Maharry, K. S., et al. (2010) · Cancer Cell · doi:10.1016/j.ccr.2010.03.008 · Cited by 244
HCV-Induced miR-21 Contributes to Evasion of Host Immune System by Targeting MyD88 and IRAK1
Chen, Y., Chen, J., Wang, H., Shi, J., Wu, K., Liu, S., Liu, Y., & Wu, J. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003248 · Cited by 243
Genome-wide Analysis Identifies Interleukin-10 mRNA as Target of Tristetraprolin
Stoecklin, G., Tenenbaum, S. A., Mayo, T., Chittur, S. V., George, A. D., Baroni, T. E., Blackshear, P. J., & Anderson, P. J. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m709657200 · Cited by 239
B-cell Receptor Activation Induces BIC/miR-155 Expression through a Conserved AP-1 Element
Yin, Q., Wang, X., McBride, J., Fewell, C., & Flemington, E. K. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m708218200 · Cited by 232
miR‐301a as an NF‐κB activator in pancreatic cancer cells
Lu, Z., Li, Y., Takwi, A. A., Li, B., Zhang, J., Conklin, D. J., Young, K. H., Martin, R. C. G., & Li, Y. (2010) · The EMBO Journal · doi:10.1038/emboj.2010.296 · Cited by 232
MicroRNAs as mediators of viral evasion of the immune system
Cullen, B. R. (2013) · Nature Immunology · doi:10.1038/ni.2537 · Cited by 230
IL-10–induced microRNA-187 negatively regulates TNF-α, IL-6, and IL-12p40 production in TLR4-stimulated monocytes
Rossato, M., Curtale, G., Tamassia, N., Castellucci, M., Mori, L., Gasperini, S., Mariotti, B., De Luca, M., Mirolo, M., Cassatella, M. A., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1209100109 · Cited by 215
NF-kappaB p65-Dependent Transactivation of miRNA Genes following Cryptosporidium parvum Infection Stimulates Epithelial Cell Immune Responses
Zhou, R., Hu, G., Liu, J., Gong, A.-Y., Drescher, K. M., & Chen, X. (2009) · PLoS Pathogens · doi:10.1371/journal.ppat.1000681 · Cited by 212
Posttranscriptional regulation of interleukin-10 expression by hsa-miR-106a
Sharma, A. S., Kumar, M., Aich, J., Hariharan, M., Brahmachari, S. K., Agrawal, A., & Ghosh, B. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0808743106 · Cited by 200
Binding of NF-kappaB p65 subunit to the promoter elements is involved in LPS-induced transactivation of miRNA genes in human biliary epithelial cells
Zhou, R., Hu, G., Gong, A.-Y., & Chen, X. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq056 · Cited by 197
Silencing of microRNA-155 in mice during acute inflammatory response leads to derepression of c/ebp Beta and down-regulation of G-CSF
Worm, J., Stenvang, J., Petri, A., Frederiksen, K. S., Obad, S., Elmén, J., Hedtjärn, M., Straarup, E. M., Hansen, J. B., & Kauppinen, S. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp577 · Cited by 192
MicroRNA-155 Silencing Enhances Inflammatory Response and Lipid Uptake in Oxidized Low-Density Lipoprotein-Stimulated Human THP-1 Macrophages
Huang, R., Hu, G., Lin, B., Lin, Z., & Sun, C. (2010) · Journal of Investigative Medicine · doi:10.2310/jim.0b013e3181ff46d7 · Cited by 188
MicroRNA Regulation of IFN-β Protein Expression: Rapid and Sensitive Modulation of the Innate Immune Response
Witwer, K. W., Sisk, J. M., Gama, L., & Clements, J. E. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0902712 · Cited by 186
Identification of MyD88 as a novel target of miR‐155, involved in negative regulation of Helicobacter pylori‐induced inflammation
Tang, B., Xiao, B., Liu, Z., Li, N., Zhu, E.-D., Li, B.-S., Xie, Q.-H., Zhuang, Y., Zou, Q.-M., & Mao, X.-H. (2010) · FEBS Letters · doi:10.1016/j.febslet.2010.02.063 · Cited by 185
MicroRNA-27b Contributes to Lipopolysaccharide-mediated Peroxisome Proliferator-activated Receptor γ (PPARγ) mRNA Destabilization
Jennewein, C., von Knethen, A., Schmid, T., & Brüne, B. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.066399 · Cited by 183
The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor
Papadopoulou, A. S., Dooley, J., Linterman, M. A., Pierson, W., Ucar, O., Kyewski, B., Žuklys, S., Holländer, G. A., Matthys, P., Gray, D. H. D., et al. (2011) · Nature Immunology · doi:10.1038/ni.2193 · Cited by 181
TLR2 Expression Is Regulated by MicroRNA miR-19 in Rheumatoid Fibroblast-like Synoviocytes
Philippe, L., Alsaleh, G., Suffert, G., Meyer, A., Georgel, P., Sibilia, J., Wachsmann, D., & Pfeffer, S. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1102348 · Cited by 178
MicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery components
Asirvatham, A. J., Gregorie, C. J., Hu, Z., Magner, W. J., & Tomasi, T. B. (2007) · Molecular Immunology · doi:10.1016/j.molimm.2007.10.035 · Cited by 175
microRNA‐210 negatively regulates LPS‐induced production of proinflammatory cytokines by targeting NF‐κB1 in murine macrophages
Qi, J., Qiao, Y., Wang, P., Li, S., Zhao, W., & Gao, C. (2012) · FEBS Letters · doi:10.1016/j.febslet.2012.03.011 · Cited by 170
miRNA regulation of cytokine genes
Asirvatham, A. J., Magner, W. J., & Tomasi, T. B. (2009) · Cytokine · doi:10.1016/j.cyto.2008.11.010 · Cited by 168
Regulation of immune responses and tolerance: the micro RNA perspective
Chen, C., Schaffert, S. A., Fragoso, R., & Loh, C. (2013) · Immunological Reviews · doi:10.1111/imr.12060 · Cited by 167
Targeting of microRNA-142-3p in dendritic cells regulates endotoxin-induced mortality.
Sun, Y.-P., Varambally, S., Maher, C., Cao, Q., Chockley, P., Toubai, T., Malter, C., Nieves, E. C., Tawara, I., Wang, Y., et al. (2011) · Blood · doi:10.1182/blood-2010-12-325647 · Cited by 161
Regulation of TLR2-Mediated Tolerance and Cross-Tolerance through IRAK4 Modulation by miR-132 and miR-212
Nahid, M. A., Yao, B., Dominguez‐Gutierrez, P. R., Kesavalu, L. N., Satoh, M., & Chan, E. K. L. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1103060 · Cited by 160
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NF-κB targets miR-16 and miR-21 in gastric cancer: involvement of prostaglandin E receptors
Shin, V. Y., Jin, H., Ng, E. K., Cheng, A. S. L., Chong, W., Wong, C. Y., Leung, W. K., Sung, J. J. �., & Chu, K. (2010) · Carcinogenesis · doi:10.1093/carcin/bgq240 · Cited by 158
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Gazzar, M. E., & McCall, C. E. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.115063 · Cited by 157
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Zhu, Q.-Y., Liu, Q., Chen, J.-X., Lan, K., & Ge, B.-X. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1000798 · Cited by 152
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Fabbri, M., Paone, A., Calore, F., Galli, R., & Croce, C. M. (2013) · RNA Biology · doi:10.4161/rna.23144 · Cited by 148
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Wang, P., Gu, Y., Zhang, Q., Han, Y., Hou, J., Lin, L., Wu, C., Bao, Y., Su, X., Jiang, M., et al. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1200609 · Cited by 148
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Benakanakere, M. R., Li, Q., Eskan, M. A., Singh, A. V., Zhao, J., Galicia, J. C., Stathopoulou, P. G., Knudsen, T. B., & Kinane, D. F. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.013862 · Cited by 147
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Wendlandt, E. B., Graff, J. W., Gioannini, T. L., McCaffrey, A. P., & Wilson, M. E. (2012) · Innate Immunity · doi:10.1177/1753425912443903 · Cited by 147
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Horwood, N. J., Mahon, T., McDaid, J., Campbell, J., Mano, H., Brennan, F. M., Webster, D., & Foxwell, B. M. J. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20021845 · Cited by 145
New Insights into the Regulation of Signalling by Toll-Like Receptors and Nod-Like Receptors
Coll, R. C., & O'Neill, L. A. J. (2010) · Journal of Innate Immunity · doi:10.1159/000315469 · Cited by 141
Toll like receptor signaling in “inflammaging”: microRNA as new players
Olivieri, F., Rippo, M. R., Prattichizzo, F., Babini, L., Graciotti, L., Recchioni, R., & Procopio, A. D. (2013) · Immunity & Ageing · doi:10.1186/1742-4933-10-11 · Cited by 141
Src homology 2 domain-containing inositol-5-phosphatase 1 (SHIP1) negatively regulates TLR4-mediated LPS response primarily through a phosphatase activity- and PI-3K-independent mechanism
An, H., Xu, H., Zhang, M., Zhou, J., Feng, T., Qian, C., Qi, R., & Cao, X. (2005) · Blood · doi:10.1182/blood-2005-01-0191 · Cited by 140
miR-146a Is Differentially Expressed by Myeloid Dendritic Cell Subsets and Desensitizes Cells to TLR2-Dependent Activation
Jurkin, J., Schichl, Y. M., Koeffel, R., Bauer, T., Richter, S., Konradi, S., Gesslbauer, B., & Strobl, H. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0903021 · Cited by 139
MicroRNA Expression Profiles of Human Blood Monocyte-derived Dendritic Cells and Macrophages Reveal miR-511 as Putative Positive Regulator of Toll-like Receptor 4
Tserel, L., Runnel, T., Kisand, K., Pihlap, M., Bakhoff, L., Kolde, R., Peterson, H., Vilo, J., Peterson, P., & Rebane, A. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.213561 · Cited by 136
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Abend, J. R., Ramalingam, D., Kieffer-Kwon, P., Uldrick, T. S., Yarchoan, R., & Ziegelbauer, J. M. (2012) · Journal of Virology · doi:10.1128/jvi.01147-12 · Cited by 135
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Xu, Z. Q., Xiao, S., Xu, P., Xie, Q., Cao, L., Wang, D., Luo, R., Zhong, Y. H., Chen, H., & Fang, L. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.198630 · Cited by 130
Structural basis for translational inhibition by the tumour suppressor Pdcd4
Loh, P. G., Yang, H., Walsh, M. A., Wang, Q., Wang, X., Cheng, Z., Liu, D. X., & Song, H. (2009) · The EMBO Journal · doi:10.1038/emboj.2008.278 · Cited by 128
MicroRNAs in the regulation of TLR and RIG-I pathways
Li, Y., & Shi, X. (2012) · Cellular and Molecular Immunology · doi:10.1038/cmi.2012.55 · Cited by 127
MicroRNA-92a Negatively Regulates Toll-like Receptor (TLR)-triggered Inflammatory Response in Macrophages by Targeting MKK4 Kinase
Lai, L., Song, Y., Liu, Y., Chen, Q., Han, Q., Chen, W., Pan, T., Zhang, Y., Cao, X., & Wang, Q. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.445429 · Cited by 126
MicroRNA-98 and let-7 Confer Cholangiocyte Expression of Cytokine-Inducible Src Homology 2-Containing Protein in Response to Microbial Challenge
Hu, G., Zhou, R., Liu, J., Gong, A., Eischeid, A. N., Dittman, J. W., & Chen, X. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0804362 · Cited by 119
The roles of microRNAs in mammalian virus infection
Grassmann, R., & Jeang, K. (2008) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2008.05.005 · Cited by 118
Control of cytokine mRNA expression by RNA-binding proteins and microRNAs
Palanisamy, V., Jakymiw, A., Van Tubergen, E. A., D’Silva, N. J., & Kirkwood, K. L. (2012) · Journal of Dental Research · doi:10.1177/0022034512437372 · Cited by 117
MicroRNA-146a Represses Mycobacteria-Induced Inflammatory Response and Facilitates Bacterial Replication via Targeting IRAK-1 and TRAF-6
Li, S., Yue, Y., Xu, W., & Xiong, S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0081438 · Cited by 115
Inductive microRNA‐21 impairs anti‐mycobacterial responses by targeting IL‐12 and Bcl‐2
Wu, Z., Lu, H., Sheng, J., & Li, L. (2012) · FEBS Letters · doi:10.1016/j.febslet.2012.06.004 · Cited by 114
MicroRNA regulation of innate immune responses in epithelial cells
Zhou, R., O’Hara, S. P., & Chen, X. (2011) · Cellular and Molecular Immunology · doi:10.1038/cmi.2011.19 · Cited by 111
NFκB p50-CCAAT/Enhancer-binding Protein β (C/EBPβ)-mediated Transcriptional Repression of MicroRNA let-7i following Microbial Infection
O’Hara, S. P., Splinter, P. L., Gajdos, G. B., Trussoni, C. E., Fernández-Zapico, M. E., Chen, X., & LaRusso, N. F. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.041640 · Cited by 104
MicroRNA-mediated downregulation of mTOR/FGFR3 controls tumor growth induced by Src-related oncogenic pathways
Oneyama, C., Ikeda, J., Okuzaki, D., Suzuki, K., Kanou, T., Shintani, Y., Morii, E., Okumura, M., Aozasa, K., & Okada, M. (2011) · Oncogene · doi:10.1038/onc.2011.63 · Cited by 103
MicroRNA-146 inhibits pro-inflammatory cytokine secretion through IL-1 receptor-associated kinase 1 in human gingival fibroblasts
Xie, Y., Shu, R., Jiang, S., Liu, D.-L., Ni, J., & Zhang, X. (2013) · Journal of Inflammation · doi:10.1186/1476-9255-10-20 · Cited by 102
MicroRNA-26a negatively regulates toll-like receptor 3 expression of rat macrophages and ameliorates pristane induced arthritis in rats
Jiang, C., Zhu, W., Xu, J., Wang, B., Hou, W., Zhang, R., Zhong, N., Ning, Q., Han, Y., Yu, H., et al. (2014) · Arthritis Research & Therapy · doi:10.1186/ar4435 · Cited by 102
Differential regulation of microRNA-146a and microRNA-146b-5p in human retinal pigment epithelial cells by interleukin-1β, tumor necrosis factor-α, and interferon-γ.
Kutty, R. K., Nagineni, C. N., Samuel, W., Vijayasarathy, C., Jaworski, C. J., Duncan, T. E., Cameron, J. E., Flemington, E. K., Hooks, J. J., & Redmond, T. M. (2013) · Europe PMC (PubMed Central) · Cited by 101
The Role of Ets2 Transcription Factor in the Induction of MicroRNA-155 (miR-155) by Lipopolysaccharide and Its Targeting by Interleukin-10
Quinn, S. R., Mangan, N. E., Caffrey, B. E., Gantier, M. P., Williams, B. R. G., Hertzog, P. J., McCoy, C. E., & O'Neill, L. A. J. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.522730 · Cited by 100
MiR-199a attenuates endometrial stromal cell invasiveness through suppression of the IKK /NF- B pathway and reduced interleukin-8 expression
Dai, L., Gu, L., & Di, W. J. (2011) · Molecular Human Reproduction · doi:10.1093/molehr/gar066 · Cited by 99
The regulation of toll-like receptor 2 by miR-143 suppresses the invasion and migration of a subset of human colorectal carcinoma cells
Guo, H., Chen, Y., Hu, X., Qian, G., Ge, S., & Zhang, J. (2013) · Molecular Cancer · doi:10.1186/1476-4598-12-77 · Cited by 99
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Xu, G., Zhang, Z., Xing, Y., Wei, J., Ge, Z., Liu, X., Zhang, Y., & Huang, X. (2013) · Journal of Cellular Biochemistry · doi:10.1002/jcb.24734 · Cited by 96
TLRs as miRNA Receptors
Fabbri, M. (2012) · Cancer Research · doi:10.1158/0008-5472.can-12-3229 · Cited by 95
miR-107: a Toll-like receptor-regulated miRNA dysregulated in obesity and type II diabetes
Foley, N. H., & O'Neill, L. A. J. (2012) · Journal of Leukocyte Biology · doi:10.1189/jlb.0312160 · Cited by 88
MicroRNA‐98 andlet‐7Regulate Expression of Suppressor of Cytokine Signaling 4 in Biliary Epithelial Cells in Response toCryptosporidium parvumInfection
Hu, G., Zhou, R., Liu, J., Gong, A., & Chen, X. (2010) · The Journal of Infectious Diseases · doi:10.1086/653212 · Cited by 86
microRNAs are ligands of Toll-like receptors
Chen, X., Liang, H., Zhang, J., Zen, K., & Zhang, C. (2013) · RNA · doi:10.1261/rna.036319.112 · Cited by 84
MicroRNA-146a Is Upregulated by and Negatively Regulates TLR2 Signaling
Quinn, E. M., Wang, J. H., O'Callaghan, G. P., & Redmond, H. P. (2013) · PLoS ONE · doi:10.1371/journal.pone.0062232 · Cited by 82
Absence of SHIP-1 Results in Constitutive Phosphorylation of Tank-Binding Kinase 1 and Enhanced TLR3-Dependent IFN-β Production
Gabhann, J. N., Higgs, R., Brennan, K., Thomas, W., Damen, J. E., Ben Larbi, N., Krystal, G., & Jefferies, C. A. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0902589 · Cited by 81
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Cheng, Y. Z., Kuang, W., Hao, Y., Zhang, D., Lei, M., Du, L., Jiao, H., Zhang, X., & Wang, F. (2012) · Inflammation · doi:10.1007/s10753-012-9443-8 · Cited by 76
MyD88 as a target of microRNA-203 in regulation of lipopolysaccharide or Bacille Calmette-Guerin induced inflammatory response of macrophage RAW264.7 cells
Wei, J., Huang, X., Zhang, Z., Jia, W. P., Zhao, Z., Zhang, Y., Liu, X., & Xu, G. (2013) · Molecular Immunology · doi:10.1016/j.molimm.2013.03.004 · Cited by 75
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Bai, Y., Qian, C., Li, Q., Ma, F., Hou, J., Chen, Y., Wang, Q., & Cao, X. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1102371 · Cited by 74
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Lin, L., Hou, J., Ma, F., Wang, P., Liu, X., Li, N., Wang, J., Wang, Q., & Cao, X. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1203450 · Cited by 73
miR-155 mediates suppressive effect of progesterone on TLR3, TLR4-triggered immune response
Sun, Y., Cai, J., Ma, F., Lü, P., Huang, H., & Zhou, J. (2012) · Immunology Letters · doi:10.1016/j.imlet.2012.04.007 · Cited by 66
MicroRNA-466l inhibits antiviral innate immune response by targeting interferon-alpha
Li, Y., Fan, X., He, X., Sun, H., Zou, Z., Yuan, H., Xu, H., Wang, C., & Shi, X. (2012) · Cellular and Molecular Immunology · doi:10.1038/cmi.2012.35 · Cited by 66
Self-citation
AP-1-Dependent miR-21 Expression Contributes to Chemoresistance in Cancer Stem Cell-Like SP Cells
Misawa, A., Katayama, R., Koike, S., Tomida, A., Watanabe, T., & Fujita, N. (2010) · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics · doi:10.3727/096504010x12828372551759 · Cited by 65
Downregulation of PCAF by miR-181a/b provides feedback regulation to TNF-α-induced transcription of pro-inflammatory genes in liver epithelial cells,
Zhao, J., Gong, A., Zhou, R., Liu, J., Eischeid, A. N., & Chen, X.-M. (2012) · Journal of Immunology · doi:10.4049/jimmunol.1101976 · Cited by 49
PDGF induced microRNA alterations in cancer cells
Shao, M., Rossi, S., Chelladurai, B. S., Shimizu, M., Ntukogu, O., Ivan, M., Calin, G. A., & Matei, D. E. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkq1305 · Cited by 46
Identification of microRNAs That Regulate TLR2-Mediated Trophoblast Apoptosis and Inhibition of IL-6 mRNA
Garg, M., Potter, J. A., & Abrahams, V. M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0077249 · Cited by 45
Letter from the Editor
Schroeder, R., Gardner, P. P., & Riedmann, E. M. (2013) · RNA Biology · doi:10.4161/rna.23502 · Cited by 43
Recognition of pathogen-associated nucleic acids by endosomal nucleic acid-sensing toll-like receptors
He, X., Jia, H., Jing, Z., & Liu, D. X. (2013) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gms122 · Cited by 42
Self-citation
A novel data mining system points out hidden relationships between immunological markers in multiple sclerosis
Gironi, M., Saresella, M., Rovaris, M., Vaghi, M. M. S., Nemni, R., Clerici, M., & Grossi, E. (2013) · Immunity & Ageing · doi:10.1186/1742-4933-10-1 · Cited by 37
Both miR-17-5p and miR-20a Alleviate Suppressive Potential of Myeloid-Derived Suppressor Cells by Modulating STAT3 Expression
Zhang, M.-M., Liu, Q.-F., Mi, S., Liang, X., Zhang, Z.-Q., Su, X.-M., Liu, J., Chen, Y., Wang, M., Zhang, Y., et al. (2011) · Journal of Immunology · doi:10.4049/jimmunol.1002989 · Cited by 29
Cloning and functional characterization of rat stimulator of interferon genes (STING) regulated by miR-24
Huang, Z., Chen, X., Yu, B., & Chen, D. (2012) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2012.02.010 · Cited by 27
Tumor necrosis factor receptor associated factor-4: An adapter protein overexpressed in metastatic prostate cancer is regulated by microRNA-29a
Ahmed, F., Shiraishi, T., Vessella, R. L., & Kulkarni, P. (2013) · Oncology Reports · doi:10.3892/or.2013.2789 · Cited by 26
[Influence of miR-122 on IFN-α treatment for HCV infection].
Li, S., Chen, Z., & Zhu, H. (2011) · PubMed · Cited by 2

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2013, Acta Biochimica et Biophysica Sinica, 45, 240
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2013, Cell, 53, 516
2013, PLoS One, 8
2013, PLoS Pathogens, 9
2012, PLoS One, 7
2013, Proceedings of the National Academy of Sciences of the United States of America, 110, 11449
2013, PLoS One, 8
2013, PLoS One, 8
2012, Cellular & Molecular Immunology, 9, 495
2013, Molecular Vision, 19, 737
10.4255/mcpharmacol.11.19 · DOI
2011, Zhejiang Da Xue Xue Bao Yi Xue Ban, 40, 588
2012, PLoS Pathogens, 8
2013, RNA Biology, 10, 1

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Authors: He, X., Jing, Z., & Cheng, G.
Affiliations: Lanzhou Veterinary Research Institute (CN)
Shanghai Veterinary Research Institute (CN)
Corresponding author: Jing, Zhizhong
Cheng, Guofeng
ORCID: He, Xiaobing
Jing, Zhizhong
Cheng, Guofeng
Venue: BioMed Research International
Publisher: Wiley
Published: 2014
Volume: 2014
Pages: 1-14
ISSN: 1110-7243 (ISSN-L)
2314-6133
2314-6141
DOI: 10.1155/2014/945169
PMC: PMC3977468
OpenAlex: W2066588601
Cited by: 238
References: 150
Citations by year: 2026: 5 · 2025: 7 · 2024: 17 · 2023: 12 · 2022: 14 · 2021: 43 · 2020: 28 · 2019: 21 · 2018: 19 · 2017: 28 · 2016: 21 · 2015: 15 · 2014: 8
FWCI: 2.34
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by
creativecommons.org/licenses/by/3.0/ (unspecified)
Locations: BioMed Research International (publishedVersion, cc-by)
Europe PMC (PubMed Central) (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
Funders: National Natural Science Foundation of China (31302072, 31372423, 30871884)
Topics: Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › MicroRNA in disease regulation
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Inflammasome and immune disorders
Keywords: microRNA, Toll-like receptors, innate immunity, pattern recognition receptors, miRNA expression regulation, microRNA target regulation, transcription factors, cytokines, tissue homeostasis
MeSH terms: Animals, Humans, Signal Transduction, MicroRNAs, Toll-Like Receptors

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MicroRNAs: New Regulators of Toll-Like Receptor Signalling Pathways

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