Leptin, neuroinflammation and obesity

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Identification and expression cloning of a leptin receptor, OB-R.

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Role of leptin in the neuroendocrine response to fasting

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A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

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Effects of Recombinant Leptin Therapy in a Child with Congenital Leptin Deficiency

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Obesity is associated with hypothalamic injury in rodents and humans.

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Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action

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Anatomy and regulation of the central melanocortin system

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Recombinant Leptin for Weight Loss in Obese and Lean Adults: A Randomized, Controlled, Dose-Escalation Trial

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Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity

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Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice

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Consumption of a Fat-Rich Diet Activates a Proinflammatory Response and Induces Insulin Resistance in the Hypothalamus

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A leptin missense mutation associated with hypogonadism and morbid obesity

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Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity

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Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans

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Identification of SOCS-3 as a Potential Mediator of Central Leptin Resistance

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Leptin: a review of its peripheral actions and interactions

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Diabetes, a New Mutation in the Mouse

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Leptin Receptor Signaling in Midbrain Dopamine Neurons Regulates Feeding

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Endoplasmic Reticulum Stress Plays a Central Role in Development of Leptin Resistance

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Microglia: Scapegoat, saboteur, or something else?

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Long term maintenance of weight loss with non-surgical interventions in obese adults: Systematic review and meta-analyses of randomised controlled trials

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The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors.

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Activation of Downstream Signals by the Long Form of the Leptin Receptor

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Effects of parabiosis of obese with diabetes and normal mice.

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Physiology of leptin: energy homeostasis, neuroendocrine function and metabolism

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Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity

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Leptin Regulation of the Mesoaccumbens Dopamine Pathway

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The role of SOCS-3 in leptin signaling and leptin resistance

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Molecular and anatomical determinants of central leptin resistance

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Leptin Receptor Signaling and the Regulation of Mammalian Physiology

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Structure, production and signaling of leptin

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Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity

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Effects of parabiosis of normal with genetically diabetic mice

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Direct and indirect effects of leptin on adipocyte metabolism

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TLR4 at the Crossroads of Nutrients, Gut Microbiota, and Metabolic Inflammation

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Trends in child and adolescent obesity prevalence in economically advanced countries according to socioeconomic position: a systematic review

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Why is obesity such a problem in the 21st century? The intersection of palatable food, cues and reward pathways, stress, and cognition

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Defective Hypothalamic Autophagy Directs the Central Pathogenesis of Obesity via the IκB Kinase β (IKKβ)/NF-κB Pathway

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The hardship of obesity: a soft-wired hypothalamus

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Evolution of Leptin Structure and Function

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Altered hypothalamic function in diet-induced obesity

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Hypothalamic ERK Mediates the Anorectic and Thermogenic Sympathetic Effects of Leptin

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Genetic approaches to understanding human obesity

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The Long Form of the Leptin Receptor Regulates STAT5 and Ribosomal Protein S6 via Alternate Mechanisms

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Why treatments for obesity don’t last

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Radiologic evidence that hypothalamic gliosis is associated with obesity and insulin resistance in humans

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Partial Reversibility of Hypothalamic Dysfunction and Changes in Brain Activity After Body Mass Reduction in Obese Subjects

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Could the Quality of Dietary Fat, and Not Just Its Quantity, Be Related to Risk of Obesity?

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Leptin and leptin receptor-related monogenic obesity

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GABAergic signaling by AgRP neurons prevents anorexia via a melanocortin-independent mechanism

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A New Missense Mutation in the Leptin Gene Causes Mild Obesity and Hypogonadism without Affecting T Cell Responsiveness

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Mechanisms of Mononuclear Phagocyte Recruitment in Alzheimers Disease

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A novel homozygous missense mutation of the leptin gene (N103K) in an obese Egyptian patient

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Longitudinal trends in global obesity research and collaboration: a review using bibliometric metadata

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OBESITY AND DIABETES MELLITUS IN A RAT WITH HYPOTHALAMIC LESIONS

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Leptin deficiency andleptingene mutations in obese children from Pakistan

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Homozygosity for a novel missense mutation in the leptin receptor gene (P316T) in two Egyptian cousins with severe early onset obesity

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Saturated Fatty Acids Modulate Autophagy’s Proteins in the Hypothalamus

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Shp2 Controls Female Body Weight and Energy Balance by Integrating Leptin and Estrogen Signals

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Truncated Human Leptin (Δ133) Associated with Extreme Obesity Undergoes Proteasomal Degradation after Defective Intracellular Transport*

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Distinct regulation of hypothalamic and brown/beige adipose tissue activities in human obesity

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Physical activity, fat intake and body fat

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Pregnancy in a Woman with a Leptin-Receptor Mutation

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A novel mutation of the leptin gene in an Indian patient

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Obesity Following Unilateral Hypothalamic Lesions in Rats

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The severely obese patient—a genetic work-up

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A new mutation c.422C>G (p.S141C) in homoand heterozygous forms of the human leptin gene

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Hunting for the functions of short leptin receptor isoforms

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Chronobiology of Recombinant Leptin Therapy

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Untitled work

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The Role of Exercise in the Interplay between Myokines, Hepatokines, Osteokines, Adipokines, and Modulation of Inflammation for Energy Substrate Redistribution and Fat Mass Loss: A Review

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Obesity as a Risk Factor for Dementia and Alzheimer’s Disease: The Role of Leptin

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Structural Brain Changes Associated with Overweight and Obesity

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Hypothalamic Microglial Activation in Obesity: A Mini-Review

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Obesity and Multiple Sclerosis—A Multifaceted Association

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Multiple sclerosis and obesity: The role of adipokines

Correale, J. D., & Marrodán, M. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1038393 · Cited by 67 · see citing works

Quality of Life and a Surveillant Endocannabinoid System

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Visceral Adipose Tissue Accumulation and Residual Cardiovascular Risk

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Leptin and leptin resistance in obesity: current evidence, mechanisms and future directions

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The Role of Physical Exercise to Improve the Browning of White Adipose Tissue via POMC Neurons

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Hypothalamic IRX3: A New Player in the Development of Obesity

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Lipid metabolic dysregulation-induced neuroinflammation in the pathophysiology of major depressive disorder

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Fatty acids role on obesity induced hypothalamus inflammation: From problem to solution – A review

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Emerging roles of leptin in Parkinson’s disease: Chronic inflammation, neuroprotection and more?

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The Vicious Cycle of Obesity and Low Back Pain: A Comprehensive Review

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Frozen Shoulder as a Metabolic and Immune Disorder: Potential Roles of Leptin Resistance, JAK-STAT Dysregulation, and Fibrosis

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The interactions between adipose tissue secretions and Parkinson's disease: The role of leptin

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Hypothalamic Neuropeptides Expression and Hypothalamic Inflammation in Adult Rats that Were Exposed to Tobacco Smoke during Breastfeeding: Sex-Related Differences

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U-Shaped Relationship between Serum Leptin Concentration and Cognitive Performance in Older Asian Adults

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