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Diet-induced obese mice develop peripheral, but not central, resistance to leptin.

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Key enzyme in leptin-induced anorexia

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Attenuation of Leptin Action and Regulation of Obesity by Protein Tyrosine Phosphatase 1B

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SOCS3 Mediates Feedback Inhibition of the Leptin Receptor via Tyr985

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Hypothalamic sensing of fatty acids

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Insulin Activation of Phosphatidylinositol 3-Kinase in the Hypothalamic Arcuate Nucleus

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The hypothalamic arcuate nucleus: A key site for mediating leptin’s effects on glucose homeostasis and locomotor activity

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IRS-2 pathways integrate female reproduction and energy homeostasis

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SOCS-3 Inhibits Insulin Signaling and Is Up-regulated in Response to Tumor Necrosis Factor-α in the Adipose Tissue of Obese Mice

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Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation

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Divergent Roles of SHP-2 in ERK Activation by Leptin Receptors

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Activation of Jak2 Catalytic Activity Requires Phosphorylation of Y 1007 in the Kinase Activation Loop

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CIS3/SOCS-3 Suppresses Erythropoietin (EPO) Signaling by Binding the EPO Receptor and JAK2

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Role of signal transducer and activator of transcription 3 in regulation of hypothalamic proopiomelanocortin gene expression by leptin

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Leptin Receptor (OB-R) Signaling

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The role of leptin receptor signaling in feeding and neuroendocrine function

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Intracerebroventricular Leptin Regulates Hepatic but Not Peripheral Glucose Fluxes

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Roles for leptin receptor/STAT3-dependent and -independent signals in the regulation of glucose homeostasis

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Feedback inhibition of leptin receptor/Jak2 signaling via Tyr1138 of the leptin receptor and suppressor of cytokine signaling 3.

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Arcuate Nucleus-Specific Leptin Receptor Gene Therapy Attenuates the Obesity Phenotype of Koletsky (fak/fak) Rats

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LRb-STAT3 Signaling Is Required for the Neuroendocrine Regulation of Energy Expenditure by Leptin

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Leptin as a Therapeutic Agent--Trials and Tribulations

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Tyrosine Phosphorylation of Jak2 in the JH2 Domain Inhibits Cytokine Signaling

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Tyrosine 813 Is a Site of JAK2 Autophosphorylation Critical for Activation of JAK2 by SH2-Bβ

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Diet-Induced Obesity Causes Severe but Reversible Leptin Resistance in Arcuate Melanocortin Neurons

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Hypothalamic Tanycytes Are an ERK-Gated Conduit for Leptin into the Brain

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