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Cited by 2,082Aortic Disease and Treatment ApproachesConnective tissue disorders researchAortic aneurysm repair treatments

2022 ACC/AHA guideline for the diagnosis and management of aortic disease: a report of the American heart association/American college of cardiology joint committee on clinical practice guidelines

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Isselbacher, Eric M., Preventza, Ourania, Hamilton Black, James, Augoustides, John G., Beck, Adam W., Bolen, Michael A., Braverman, Alan C., Bray, Bruce E. +39 more·2022·Circulation
DOI 10.1161/cir.0000000000001106PMC PMC9876736
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Abstract

AIM: The "2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease" provides recommendations to guide clinicians in the diagnosis, genetic evaluation and family screening, medical therapy, endovascular and surgical treatment, and long-term surveillance of patients with aortic disease across its multiple clinical presentation subsets (ie, asymptomatic, stable symptomatic, and acute aortic syndromes). METHODS: A comprehensive literature search was conducted from January 2021 to April 2021, encompassing studies, reviews, and other evidence conducted on human subjects that were published in English from PubMed, EMBASE, the Cochrane Library, CINHL Complete, and other selected databases relevant to this guideline. Additional relevant studies, published through June 2022 during the guideline writing process, were also considered by the writing committee, where appropriate. Structure: Recommendations from previously published AHA/ACC guidelines on thoracic aortic disease, peripheral artery disease, and bicuspid aortic valve disease have been updated with new evidence to guide clinicians. In addition, new recommendations addressing comprehensive care for patients with aortic disease have been developed. There is added emphasis on the role of shared decision making, especially in the management of patients with aortic disease both before and during pregnancy. The is also an increased emphasis on the importance of institutional interventional volume and multidisciplinary aortic team expertise in the care of patients with aortic disease.

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  • Beta-blockers, angiotensin receptor blockers, or both have been shown to prevent aortic dilation and aortic dissections in individuals with other aortopathy conditions.

    “Medical therapy of hypertension for individuals with TS and aortic dilation should preferably include a beta-blocker, angiotensin receptor blocker (ARB), or both, which have been shown to prevent aortic dilation and aortic dissections in individuals with other aortopathy conditions.439”

    From Clinical practice guidelines for the care of girls and women with Turner syndrome. (2024) · cites this paper as [439]

  • Applying the current absolute diameter thresholds for aortic dilation (>4.0 cm) or aneurysm (>4.5 cm) to adults with TS would almost certainly lead to delayed recognition of aortic disease.

    “In this context, applying the current absolute diameter thresholds for aortic dilation (>4.0 cm) or aneurysm (>4.5 cm) to adults with TS would almost certainly lead to delayed recognition of aortic disease.439”

    From Clinical practice guidelines for the care of girls and women with Turner syndrome. (2024) · cites this paper as [439]

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Authors
Isselbacher, E. M., Preventza, O., Hamilton Black, J., Augoustides, J. G., Beck, A. W., Bolen, M. A., Braverman, A. C., Bray, B. E., Brown-Zimmerman, M. M., Chen, E. P., Collins, T. J., DeAnda, A., Fanola, C. L., Girardi, L. N., Hicks, C. W., Hui, D. S., Schuyler Jones, W., Kalahasti, V., Kim, K. M., Milewicz, D. M., Oderich, G. S., Ogbechie, L., Promes, S. B., Gyang Ross, E., Schermerhorn, M. L., Singleton Times, S., Tseng, E. E., Wang, G. J., Woo, Y. J., Faxon, D. P., Upchurch, G. R., Aday, A. W., Azizzadeh, A., Boisen, M., Hawkins, B., Kramer, C. M., Luc, J. G. Y., MacGillivray, T. E., Malaisrie, S. C., Osteen, K., Patel, H. J., Patel, P. J., Popescu, W. M., Rodriguez, E., Sorber, R., Tsao, P. S., & Santos Volgman, A.
Affiliations
  • SCA representative.
  • ACR representative.
  • American Heart Association (US)
  • Lay stakeholder representative.
  • Fraunhofer Institute for Algorithms and Scientific Computing (DE)
  • AATS representative.
  • American Hospital Association (US)
  • AHA/ACC Joint Committee on Clinical Practice Guidelines liaison.
  • STS representative.
  • SVS representative.
  • AHA/ACC staff representative.
ORCID
Venue
Circulation
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2022-12-13
Volume
146
Issue
24
Pages
e334-e482
ISSN
  • 0009-7322 (ISSN-L)
  • 1524-4539
DOI
10.1161/cir.0000000000001106
PMC
PMC9876736
OpenAlex
W4307934708
Cited by
2,082
References
1,104
Citations by year
2026: 600 · 2025: 569 · 2024: 554 · 2023: 348 · 2022: 9
FWCI
239.09
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Circulation (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • U.S. Department of Veterans Affairs
  • American Heart Association
  • Massachusetts General Hospital
  • American College of Cardiology Foundation
  • University of Pennsylvania
  • CryoLife
  • Office of Science
  • National Institute of Diabetes and Digestive and Kidney Diseases (K23DK124515)
  • Division of Cardiothoracic Surgery, University of Colorado School of Medicine, Anschutz Medical Campus
Topics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Aortic Disease and Treatment Approaches
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Connective tissue disorders research
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Aortic aneurysm repair treatments
Keywords
aortic disease, thoracic aortic disease, acute aortic syndrome, aortic aneurysm, aortic dissection, bicuspid aortic valve disease, peripheral arterial disease, genetic evaluation, family screening, endovascular repair, aortic surgery, long-term surveillance, shared decision-making, pregnancy
MeSH terms
Bicuspid Aortic Valve Disease, American Heart Association, Aortic Diseases, Cardiology, Female, Humans, Pregnancy, United States, Research Report

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